MRI characteristics of the MLF in MS patients with chronic internuclear ophthalmoparesis.

abstract：:We used two analytic methods (a multichannel coulometric electrode array with high-performance liquid chromatography, and gas chromatography-mass spectrophotometry) to measure CSF dopamine (DA) and its metabolites in mildly affected, unmedicated subjects with Parkinson's disease (PD). The mean (+/- SD) concentration o...

journal_title：Neurology

authors： LeWitt PA,Galloway MP,Matson W,Milbury P,McDermott M,Srivastava DK,Oakes D

更新日期：1992-11-01 00:00:00

abstract：:We evaluated 14 patients with idiopathic optic neuritis, 50 years of age or older, within 1 month of symptomatic onset from 1980 through 1985. We obtained follow-up information from case records an average of 13 months after initial examination and from telephone interviews an average of 57 months after initial evalua...

journal_title：Neurology

authors： Jacobson DM,Thompson HS,Corbett JJ

更新日期：1988-12-01 00:00:00

abstract：OBJECTIVE:To describe the characteristics of late-onset multiple sclerosis (MS) (LOMS, 50+ years) vs adult-onset MS (AOMS, 16 to <50 years) and examine prognosis and associated risk factors. METHODS:Patients with definite MS, onset prior to July 1988, registered with a BCMS clinic before July 1998, with at least one E...

journal_title：Neurology

authors： Tremlett H,Devonshire V

更新日期：2006-09-26 00:00:00

abstract：:We report a family with Machado-Joseph disease (MJD) that was previously diagnosed with dentatorubral-pallidoluysian atrophy (DRPLA), on the basis of the neuropathologic findings. Because the clinical and pathologic reevaluation strongly suggested a diagnosis of MJD, we conducted a genetic study in the family. Two pat...

journal_title：Neurology

authors： Sakai T,Antoku Y,Kawakami H,Maruyama H,Nakamura S,Tanaka K

更新日期：1996-04-01 00:00:00

abstract：:This double-blind, placebo-controlled, crossover study of the acute treatment of migraine investigated the efficacy and tolerability of oral sumatriptan 100 mg (Imitrex) administered for up to nine attacks compared with placebo administered for up to three attacks. Patients were randomized to receive oral sumatriptan ...

journal_title：Neurology

authors： Rederich G,Rapoport A,Cutler N,Hazelrigg R,Jamerson B

更新日期：1995-08-01 00:00:00

abstract：:The authors describe two novel mutations of the acid alpha-glucosidase gene, P361L and R437C, which define the juvenile-onset glycogen storage disease type II (GSDII) in a 16-year-old Chinese patient. The asymptomatic 13-year-old brother of the proband is also a compound heterozygote of the two mutations. These result...

journal_title：Neurology

authors： Lam CW,Yuen YP,Chan KY,Tong SF,Lai CK,Chow TC,Lee KC,Chan YW,Martiniuk F

更新日期：2003-02-25 00:00:00

abstract：:The motor effects of direct agonists which act selectively on certain dopamine receptors were studied in monkeys rendered hemiparkinsonian by unilateral intracarotid injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The D-2 dopamine agonist, LY 171555, but not the D-1 agonist, SKF 38393, reduced parkin...

journal_title：Neurology

authors： Barone P,Bankiewicz KS,Corsini GU,Kopin IJ,Chase TN

更新日期：1987-10-01 00:00:00

abstract：:The incidence of contrast-induced nephropathy was examined in 1,075 patients receiving routine CT angiography and CT perfusion brain imaging at a single institution. Fifty-two patients had a creatinine rise of > or =0.5 mg/dL. In four patients (0.37%), the administration of IV contrast medium possibly contributed to r...

journal_title：Neurology

authors： Josephson SA,Dillon WP,Smith WS

更新日期：2005-05-24 00:00:00

abstract：OBJECTIVE:To evaluate the retinal nerve fiber layer (RNFL) thickness and macular volume in neuromyelitis optica (NMO) spectrum patients using optical coherence tomography (OCT). BACKGROUND:OCT can quantify damage to retinal ganglion cell axons and can identify abnormalities in multiple sclerosis and optic neuritis (ON...

journal_title：Neurology

authors： Ratchford JN,Quigg ME,Conger A,Frohman T,Frohman E,Balcer LJ,Calabresi PA,Kerr DA

更新日期：2009-07-28 00:00:00

abstract：:A 41-year-old man presented with bilateral posterior cerebral artery infarcts. He had visual object agnosia and prosopagnosia with preservation of reading abilities. There was also defective visual memory, topographic orientation, and color perception, as well as simultanagnosia. From the clinical facts and CT finding...

journal_title：Neurology

authors： Gomori AJ,Hawryluk GA

更新日期：1984-07-01 00:00:00

abstract：:Previous studies have suggested that an abnormal release of potassium from muscle may accompany attacks of paramyotonic weakness. We investigated 3 patients with paramyotonia congenita before and after the induction of forearm muscle weakness by exercise in cold water. Two of these patients had paralysis periodica par...

journal_title：Neurology

authors： Moxley RT 3rd,Ricker K,Kingston WJ,Böhlen R

更新日期：1989-07-01 00:00:00

abstract：:We evaluated the neuroprotective effect of MK-801, a noncompetitive, selective N-methyl-D-aspartate receptor antagonist, in a neonatal hypoxic-ischemic animal model. Seven-day-old rats underwent bilateral ligation of the carotid arteries followed by exposure to an 8% oxygen atmosphere for 1 hr. We sacrificed the anima...

journal_title：Neurology

authors： Hattori H,Morin AM,Schwartz PH,Fujikawa DG,Wasterlain CG

更新日期：1989-05-01 00:00:00

abstract：:We investigated the heterogeneity of serum antibodies to acetylcholine receptor (AChR) by competition with nine antihuman monoclonal antibodies in a cross-sectional study of 36 patients with myasthenia gravis (MG), and in three who showed clinical improvement associated with decrease in total anti-AChR following immun...

journal_title：Neurology

authors： Whiting PJ,Vincent A,Newsom-Davis J

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Epidemiologic and laboratory studies suggest that nonsteroidal antiinflammatory drugs (NSAIDs) reduce risk of Alzheimer disease (AD). We therefore investigated the association between use of NSAIDs, aspirin, and the non-NSAID analgesic acetaminophen with incidence of dementia and AD. METHODS:Participants in...

journal_title：Neurology

authors： Szekely CA,Breitner JC,Fitzpatrick AL,Rea TD,Psaty BM,Kuller LH,Zandi PP

更新日期：2008-01-01 00:00:00

abstract：:A 16-year-old male with a 9-year history of spontaneously arrested hydrocephalus was noted to have hydrosyringomyelia and increased intracranial pressure shortly after sustaining minor head trauma. His symptoms resolved completely following ventriculoperitoneal shunt replacement. Hydrosyringomyelia may occur in the se...

journal_title：Neurology

authors： Olson DM,Milstein JM

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Many studies have examined the role of APOE genotype in the development of dementia, specifically Alzheimer disease (AD). The APOE epsilon4 allele (APOE4) is a risk factor for both clinical and neuropathologic AD whereas the APOE epsilon2 allele (APOE2) seems to be protective. This would predict, even with a...

journal_title：Neurology

authors： Berlau DJ,Corrada MM,Head E,Kawas CH

更新日期：2009-03-03 00:00:00

abstract：OBJECTIVE:To determine the prevalence of developmental venous anomaly in adult patients with diffuse glioma. METHODS:We performed a retrospective cohort study (2010-2016) of consecutive adult patients harboring a supratentorial diffuse glioma in 2 centers: Sainte-Anne Hospital (experimental and control sets) and Pitié...

journal_title：Neurology

authors： Roux A,Edjlali M,Porelli S,Tauziede-Espariat A,Zanello M,Dezamis E,Zah-Bi G,Sanson M,Puget S,Capelle L,Varlet P,Oppenheim C,Pallud J

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential efficacy of immediate-release methylphenidate (MPH) for treating cognitive deficits in epilepsy. METHODS:This was a double-blind, randomized, single-dose, 3-period crossover study in patients with epilepsy and chronic cognitive complaints comparing the effects of placebo and MPH 10 ...

journal_title：Neurology

authors： Adams J,Alipio-Jocson V,Inoyama K,Bartlett V,Sandhu S,Oso J,Barry JJ,Loring DW,Meador K

更新日期：2017-01-31 00:00:00

abstract：OBJECTIVE:To study the difference in risk for dementing diseases between men and women. BACKGROUND:Previous studies suggest women have a higher risk for dementia than men. However, these studies include small sample sizes, particularly in the older age groups, when the incidence of dementia is highest. METHODS:Pooled...

journal_title：Neurology

authors： Andersen K,Launer LJ,Dewey ME,Letenneur L,Ott A,Copeland JR,Dartigues JF,Kragh-Sorensen P,Baldereschi M,Brayne C,Lobo A,Martinez-Lage JM,Stijnen T,Hofman A

更新日期：1999-12-10 00:00:00

abstract：:We studied acetaminophen sulfation, plasma sulfate levels, and the activity of sulfotransferase in blood platelets in patients with Parkinson's disease, Huntington's disease, and in controls and did not find any abnormality in the patient groups, independent of the use of medication. ...

journal_title：Neurology

authors： Roos RA,Steenvoorden JM,Mulder GJ,Van Kempen GM

更新日期：1993-07-01 00:00:00

abstract：:We enrolled 116 patients in a multicenter, randomized, double-blind controlled trial of an 8-week course of 11 plasma exchange (PE) treatments in exacerbations of MS. The control group received sham PE, and both groups received identical treatment with IM ACTH and oral cyclophosphamide. Serum IgG decreased in the PE a...

journal_title：Neurology

authors： Weiner HL,Dau PC,Khatri BO,Petajan JH,Birnbaum G,McQuillen MP,Fosburg MT,Feldstein M,Orav EJ

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVE:To assess whether the association between reperfusion and improved clinical outcomes after stroke differs depending on the site of the arterial occlusive lesion (AOL). METHODS:We pooled data from Solitaire With the Intention for Thrombectomy (SWIFT), Solitaire FR Thrombectomy for Acute Revascularisation (STA...

journal_title：Neurology

authors： Lemmens R,Hamilton SA,Liebeskind DS,Tomsick TA,Demchuk AM,Nogueira RG,Marks MP,Jahan R,Gralla J,Yoo AJ,Yeatts SD,Palesch YY,Saver JL,Pereira VM,Broderick JP,Albers GW,Lansberg MG,DEFUSE 2, IMS III, STAR, and SWIFT trial

更新日期：2016-02-23 00:00:00

abstract：BACKGROUND:Affective-motivational and sensory-discriminative aspects of pain were investigated in patients with mild to moderate Alzheimer disease (AD) and healthy elderly controls using the cold pressor test tolerance and repetitive stimuli of warmth and heat stimuli, evaluating the stimulus-response function. METHOD...

journal_title：Neurology

authors： Jensen-Dahm C,Werner MU,Jensen TS,Ballegaard M,Andersen BB,Høgh P,Waldemar G

更新日期：2015-04-14 00:00:00

abstract：OBJECTIVE:To determine the diagnostic value of high-resolution ultrasound (HRUS) for detection of chronic inflammatory demyelinating polyneuropathy (CIDP), Lewis-Sumner syndrome (LSS), and multifocal motor neuropathy (MMN). METHODS:Between January 2013 and January 2015, we enrolled 75 consecutive treatment-naive patie...

journal_title：Neurology

authors： Goedee HS,van der Pol WL,van Asseldonk JH,Franssen H,Notermans NC,Vrancken AJ,van Es MA,Nikolakopoulos S,Visser LH,van den Berg LH

更新日期：2017-01-10 00:00:00

abstract：:A prospective trial of plasmapheresis and azathioprine or azathioprine alone was carrier out on 20 patients with chronic progressive MS. Seven of 10 patients in each group continued therapy for 12 months. When the groups were compared by disability ratings, the combination of plasmapheresis and azathioprine was no bet...

journal_title：Neurology

authors： Tindall RS,Walker JE,Ehle AL,Near L,Rollins J,Becker D

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:Plasma exchange (PE) is used to treat severe episodes of CNS demyelination unresponsive to corticosteroids. Predictors of long-term response are not well known. METHODS:We retrospectively reviewed the medical records of 41 patients consecutively treated by PE between January 1995 and July 2007. The primary ...

journal_title：Neurology

authors： Llufriu S,Castillo J,Blanco Y,Ramió-Torrentà L,Río J,Vallès M,Lozano M,Castellà MD,Calabia J,Horga A,Graus F,Montalban X,Saiz A

更新日期：2009-09-22 00:00:00

abstract：OBJECTIVE:To evaluate relationships among cognitive, behavioral, and psychiatric/psychosocial measures assessed in a multicenter cohort of patients with amyotrophic lateral sclerosis (ALS). METHODS:Recently diagnosed patients with definite or probable ALS diagnosis were administered 7 standardized psychiatric/psychoso...

journal_title：Neurology

authors： Rabkin J,Goetz R,Murphy JM,Factor-Litvak P,Mitsumoto H,ALS COSMOS Study Group.

更新日期：2016-09-27 00:00:00

abstract：OBJECTIVE:Asians who carry the HLA-B*1502 allele have an elevated risk of developing Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) when treated with the antiepileptic drugs (AEDs) carbamazepine (CBZ) and phenytoin (PHT). With a focus on Singapore, this analysis identifies circumstances in which ge...

journal_title：Neurology

authors： Dong D,Sung C,Finkelstein EA

更新日期：2012-09-18 00:00:00

abstract：OBJECTIVE:To verify whether the change in L-dopa plasma levels after a single dose of carbidopa/L-dopa 50/200 (controlled-release) transiently modifies frontal components of somatosensory evoked potentials (SEPs) in patients with PD in parallel with improvement of motor performance. BACKGROUND:Apomorphine, a potent do...

journal_title：Neurology

authors： Ulivelli M,Rossi S,Pasqualetti P,Rossini PM,Ghiglieri O,Passero S,Battistini N

更新日期：1999-10-22 00:00:00

abstract：:The authors report a case of hereditary multiple exostoses (HME) with neurologic complications, and review the literature. A 23-year-old man exhibited a worsening spastic paraparesis with sphincter dysfunction. The cranial nerves and the exteroceptive and deep sensations were apparently undamaged. The family history, ...

journal_title：Neurology

authors： Ferrari G,Taddei L,Vivenza C,Rossi G

更新日期：1979-07-01 00:00:00