Molecular epidemiology of a nosocomial outbreak due to Enterobacter cloacae and Enterobacter agglomerans in Campinas, São Paulo, Brazil.

Abstract:

:A total of 73 isolates (57 Enterobacter cloacae and 16 Enterobacter agglomerans), recovered during an outbreak of bacteremia in the Campinas area, São Paulo, Brazil, were studied. Of these isolates, 61 were from parenteral nutrition solutions, 9 from blood cultures, 2 from a sealed bottle of parenteral nutrition solution, and one was of unknown origin. Of the 57 E. cloacae isolates, 54 were biotype 26, two were biotype 66 and one was non-typable. Of 39 E. cloacae isolates submitted to ribotyping, 87.2% showed the same banding pattern after cleavage with EcoRI and BamHI. No important differences were observed in the antimicrobial susceptibility patterns among E. cloacae isolates exhibiting the same biotype, serotype and ribotype. All E. agglomerans isolates, irrespective of their origin, showed same patterns when cleaved with EcoRI and BamHI. The results of this investigation suggest an intrinsic contamination of parenteral nutrition solutions and incriminate these products as a vehicle of infection in this outbreak.

authors

Gonçalves CR,Vaz TM,Leite D,Pisani B,Simoes M,Prandi MA,Rocha MM,Cesar PC,Trabasso P,von Nowakonski A,Irino K

doi

10.1590/s0036-46652000000100001

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

1-7

issue

1

eissn

0036-4665

issn

1678-9946

pii

S0036-4665(00)04200101

journal_volume

42

pub_type

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