Physical damage to rat cortical axons mimics early Alzheimer's neuronal pathology.

abstract：:The so-called 40 Hz oscillations are found at almost all stages of visual processing are thought to play a critical role in perception. The goal of this investigation was to look at the presence of stimulus-specific oscillations in the lateral posterior-pulvinar complex of the thalampus (LP-P) for which the oscillatio...

journal_title：Neuroreport

authors： Shumikhina S,Molotchnikoff S

更新日期：1995-11-27 00:00:00

abstract：:The current study aimed to investigate the altered cerebellar-cerebral functional connectivity (FC) induced by radiotherapy to nasopharyngeal carcinoma (NPC) patients. Twenty-four NPC patients without treatment, and 35 NPC patients receiving radiotherapy underwent functional MRI scanning. Montreal cognitive assessment...

journal_title：Neuroreport

authors： Ma Q,Zeng LL,Qin J,Luo Z,Su J,Wu D,Qiu S,Hu D

更新日期：2017-08-16 00:00:00

abstract：:Changes in nitric oxide (NO) concentration and cerebral blood flow (CBF) in the parietal cortex during hypercapnoea were investigated in anaesthetized rats, using a NO-selective electrode and laser Doppler flowmetry. When hypercapnoea was induced by inhalation of 5% CO2 for 10 min, both the NO concentration and CBF in...

journal_title：Neuroreport

authors： Harada M,Fuse A,Tanaka Y

更新日期：1997-03-03 00:00:00

abstract：:A polymorphism of the apolipoprotein E gene, in particular the epsilon 4 allele (ApoE4), has been associated with impaired neuronal phospholipid metabolism and synapse reorganization and has been implicated in several neurodegenerative disorders. Since selective neuronal cell lose and aberrant axonal reorganization re...

journal_title：Neuroreport

authors： Blümcke I,Brockhaus A,Scheiwe C,Rollbrocker B,Wolf HK,Elger CE,Wiestler OD

更新日期：1997-03-24 00:00:00

abstract：:CEP-1347 inhibits the signalling pathway of c-jun-N-terminal kinase, and is neuroprotective in vivo and in vitro. Embryonic chick dorsal root ganglion neurones are dependent on NGF for survival and neurite outgrowth; NGF withdrawal results in apoptotic cell death. We examined the neuroprotective and neurite outgrowth ...

journal_title：Neuroreport

authors： Bilsland JG,Harper SJ

更新日期：2003-05-23 00:00:00

abstract：:To test the hypothesis that the pedunclopontine tegmental nucleus (PPTg) plays a role in anxiety, rats with electrolytic lesions of the PPTg were tested in two animal models of anxiety, the elevated plus maze and the social interaction tests. Histological analysis showed that lesions were concentrated on the caudal ha...

journal_title：Neuroreport

authors： Podhorna J,Franklin KB

更新日期：1998-06-01 00:00:00

abstract：:Regulation of CNTF mRNA was investigated in primary cortical astrocytes cultured from newborn rats and in C6 glioma cells. Northern blot analysis indicated that semi-confluent astrocyte cell cultures. CNTF added to confluent astrocyte cultures down-regulated CNTF message in a dose-dependent fashion. In contrast, when ...

journal_title：Neuroreport

authors： Meyer V,Unsicker K

更新日期：1994-10-03 00:00:00

abstract：:4-Aminobenzovesamicol was used to test whether activation of protein kinase C protects the vesicular acetylcholine transporter from interaction with vesamicol-like drugs. The essentially irreversible vesamicol analog inhibits the release of newly synthesized [3H]acetylcholine from stimulated hippocampal slices. Prior ...

journal_title：Neuroreport

authors： Clarizia AD,Gomez MV,Romano-Silva MA,Parsons SM,Prado VF,Prado MA

更新日期：1999-09-09 00:00:00

abstract：:The spatial-temporal expression and function of Drosophila melanogaster homothorax (hth) and its vertebrate homologue Meis2 in the eye anlage show a high degree of evolutionary conservation. Both are expressed by progenitor cells ahead of the neurogenic wave front, promote rapid proliferation of these cells, and are d...

journal_title：Neuroreport

authors： Heine P,Dohle E,Schulte D

更新日期：2009-02-18 00:00:00

abstract：:This study was undertaken to establish a method for the culture of organotypic spinal cord slices. A long-term organotypic spinal cord slice culture was conducted from postnatal rats. Lumbar spinal cord was isolated, and meninges were removed from the spinal cord. The spinal cord was embedded in 4% agarose, and was se...

journal_title：Neuroreport

authors： Liu JJ,Huang YJ,Xiang L,Zhao F,Huang SL

更新日期：2017-11-08 00:00:00

abstract：:The phonemic structure of the maternal language determines the way of perceiving speech signals. A typical example is that native Japanese listeners map two English phonemes, /r/ and /l/, onto the same /R/. This perceptual assimilation of speech sounds has been associated with the left and/or right posterior perisylvi...

journal_title：Neuroreport

authors： Hara NF,Nakamura K,Kuroki C,Takayama Y,Ogawa S

更新日期：2007-10-08 00:00:00

abstract：:The purpose of the present study was to determine the cortical areas contributing to the influence of the previous movement on the current movement. Right-handed healthy human participants abducted and then adducted the left index finger in response to a start cue. Twenty consecutive trials with 10 s intertrial interv...

journal_title：Neuroreport

authors： Oda H,Sawaguchi Y,Kunimura H,Kawasaki T,Hiraoka K

更新日期：2020-12-30 00:00:00

abstract：:Although decision-making is typically seen as a rational process, emotions play a role in tasks that include unfairness. Recently, activation in the right dorsolateral prefrontal cortex during offers experienced as unfair in the Ultimatum Game was suggested to subserve goal maintenance in this task. This is restricted...

journal_title：Neuroreport

authors： van 't Wout M,Kahn RS,Sanfey AG,Aleman A

更新日期：2005-11-07 00:00:00

abstract：:A prominent theory of the N2 event-related potential component holds that the 'oddball' N2 is generated in the anterior cingulate cortex. However, observations of oddball N2s with posterior scalp distributions are inconsistent with this hypothesis. We suggest that variability in the topology of the oddball N2 is a key...

journal_title：Neuroreport

authors： Warren CM,Tanaka JW,Holroyd CB

更新日期：2011-12-07 00:00:00

abstract：:In previous studies, we demonstrated functional neuronal and dopaminergic differentiation of fetal mesencephalic neural precursor cells. The major factors for orienting their progeny towards a dopaminergic phenotype are forskolin and interleukin-1beta. Here, we investigated the effects of dexamethasone (10 microM) on ...

journal_title：Neuroreport

authors： Sabolek M,Herborg A,Schwarz J,Storch A

更新日期：2006-11-06 00:00:00

abstract：:Sulphated cholecystokinin-8 (CCK-8) given into the neostriatum of the rat by in vivo microdialysis produced a concentration-dependent (1-100 microM) increase in extracellular aspartate (Asp) and dynorphin B (Dyn B), but not in glutamate, GABA or dopamine levels. The increase in Asp levels produced by 10 microM CCK-8 w...

journal_title：Neuroreport

authors： You ZB,Pettersson E,Herrera-Marschitz M,Hökfelt T,Terenius L,Nylander I,Goiny M,Hughes J,O'Connor WT,Ungerstedt U

更新日期：1994-11-21 00:00:00

abstract：:The first step in olfactory transduction is the recognition of odor molecules by membrane bound receptors belonging to the superfamily of G-protein coupled receptors; other members of this family are involved in neurotransmission. Based on the considerable homology between individual members of this family, we have in...

journal_title：Neuroreport

authors： Firestein S,Shepherd GM

更新日期：1992-08-01 00:00:00

abstract：:Although prenatal stress has been repeatedly shown to inhibit adult neurogenesis in the dentate gyrus of offspring, its effects on embryonic and early postnatal brain development are not well described. Here, using the cell proliferation marker 5-bromo-2'-deoxyuridine, we examine for the first time the effect of prena...

journal_title：Neuroreport

authors： Kawamura T,Chen J,Takahashi T,Ichitani Y,Nakahara D

更新日期：2006-10-02 00:00:00

abstract：:The neuroprotective effects of netrin-1 after spinal cord injury and its specific molecular mechanisms have not been elucidated. In our study, Western blot, transferase UTP nick end labeling staining and immunofluorescence staining first showed that netrin-1 significantly decreased the expression levels of caspase-3, ...

journal_title：Neuroreport

authors： Gao K,Niu J,Dang X

更新日期：2020-05-07 00:00:00

abstract：:Glutamate excitotoxicity has been suggested to play a role in amyotrophic lateral sclerosis (ALS), yet it remains unclear why some groups of motoneurons (MNs) are more vulnerable to degeneration than others. Our aim was to compare, in normal adult rats, the expression of Group I metabotropic glutamate receptors (mGluR...

journal_title：Neuroreport

authors： Laslo P,Lipski J,Funk GD

更新日期：2001-07-03 00:00:00

abstract：:Episodic memory for simple commands is better following enacted than verbal encoding. This has been proposed to be due to the possibility to base retrieval on motor information. Here we used PET to test the hypothesis that motor brain areas show increased retrieval-related activity following enacted compared to verbal...

journal_title：Neuroreport

authors： Nilsson LG,Nyberg L,Klingberg T,Aberg C,Persson J,Roland PE

更新日期：2000-07-14 00:00:00

abstract：:Subcortical visual inputs to motion-selective cortex in primates survive after damage to the primary visual cortex (area 17/V1). Activation of human motion cortex was examined using scalp electrodes in a V1-damaged hemianope. Blind field motion-onset visual evoked potentials (VEPs) shared many of the characteristics a...

journal_title：Neuroreport

authors： Benson PJ,Guo K,Hardiman MJ

更新日期：1999-11-26 00:00:00

abstract：:Retinal gamma-aminobutyric acid type C (GABA[C]) receptors are believed to consist of rho subunits. The pharmacological properties of GABA(C) receptors appear to vary among different species. Since the mouse is an important model for gene targeting and behavioral studies, this study was aimed at cloning rho subunits i...

journal_title：Neuroreport

authors： Greka A,Koolen JA,Lipton SA,Zhang D

更新日期：1998-01-26 00:00:00

abstract：:The pattern of distribution and co-localization of nitric oxide synthase (NOS) and quinacrine fluorescence (indicative of vesicular adenosine 5'-triphosphate, ATP), and co-localization of NADPH-diaphorase (NADPH-d) activity and NOS-immunoreactivity in the myenteric plexus of pre-term human fetal (6-17 weeks of gestati...

journal_title：Neuroreport

authors： Belai A,Burnstock G

更新日期：2000-01-17 00:00:00

abstract：:Amygdala and insula hyper-reactivity to threat is implicated in social anxiety disorder (SAD) yet inconsistencies in activation have been reported. One source of variance are individual differences in 5-HTTLPR genotype where the short (S), relative to long (L) allele, corresponds with greater amygdala activation. Howe...

journal_title：Neuroreport

authors： Klumpp H,Fitzgerald DA,Cook E,Shankman SA,Angstadt M,Phan KL

更新日期：2014-08-20 00:00:00

abstract：:Voltage-dependent outward currents were examined in CA1 neurones by whole-cell recording in slices. Nine cells were recorded with the 'standard' internal solution (KMeSO4, HEPES, EGTA, CaCl2, and MgCl2) and held a potential (-54 +/- 3 mV) at which there was no significant outward current. Cromakalim (CROM, 100 microM)...

journal_title：Neuroreport

authors： Erdemli G,Krnjević K

更新日期：1994-06-27 00:00:00

abstract：:The role of the right hemisphere in recovery of language function after left hemisphere stroke remains unclear. This prospective study aimed to determine the relationship between bilateral hemispheric changes and severity of aphasia in patients with chronic left hemisphere stroke. Twenty-three patients with left hemis...

journal_title：Neuroreport

authors： Lee WM,Kyeong S,Park EY,Yang HS,Kang H,Kim DH

更新日期：2018-01-03 00:00:00

abstract：:Brain activation of 11 healthy right-handed subjects was studied with magnetoencephalography to estimate individual hemispheric dominance for speech sounds. The auditory stimuli comprised binaurally presented Finnish vowels, tones, and piano notes in groups of two or four stimuli. The subjects were required to detect ...

journal_title：Neuroreport

authors： Gootjes L,Raij T,Salmelin R,Hari R

更新日期：1999-09-29 00:00:00

abstract：:Extrasynaptic transmission is mediated by the diffusion of transmitters, through the extracellular space (ECS) to receptors on neurons and glia. The three-dimensional diffusion of tetramethylammonium (mol. wt 74.1 kDa) was investigated in the isolated rat spinal cord at postnatal days 4-20. The diffusion parameters of...

journal_title：Neuroreport

authors： Prokopová S,Vargová L,Syková E

更新日期：1997-11-10 00:00:00

abstract：:Participation of the neuronal nicotinic receptor subunit alpha6 in a physiologically relevant receptor has yet to be demonstrated, but its high degree of expression in catecholaminergic nuclei has attracted considerable interest. To investigate the pattern of expression of the alpha6 protein, a subunit specific antibo...

journal_title：Neuroreport

authors： Göldner FM,Dineley KT,Patrick JW

更新日期：1997-08-18 00:00:00