Murine Cyp1a-1 induction in mouse hepatoma Hepa-1C1C7 cells by myristicin.

abstract：:Glucuronidated and/or methylated metabolites of the proanthocyanidin (PA) monomer (-)-epicatechin are detected in both blood and brain following feeding of rodents with a monomeric grape seed PA extract shown to reduce symptoms in a mouse model of Alzheimer's disease. To generate metabolites for future mechanistic stu...

journal_title：Biochemical and biophysical research communications

authors： Blount JW,Ferruzzi M,Raftery D,Pasinetti GM,Dixon RA

更新日期：2012-01-06 00:00:00

abstract：:Chorea-acanthocytosis (ChAc) is a hereditary neurodegenerative disorder caused by loss of function mutations in the VPS13A gene encoding chorein. Recently, using a gene-targeting technique to delete exons 60-61, we produced a ChAc-model mouse that corresponds to a human disease mutation. In this study, a comparative m...

journal_title：Biochemical and biophysical research communications

authors： Kurano Y,Nakamura M,Ichiba M,Matsuda M,Mizuno E,Kato M,Izumo S,Sano A

更新日期：2006-12-15 00:00:00

abstract：:A novel DNA sequence belonging to a new genotype of TT virus (TTV) was detected by long-distance PCR in the serum of a chronically HCV-infected patient. The isolate was designated KAV according to the patient's initials. Extending the sequence to full length revealed a 3705-nt viral genome, which is about 100 nucleoti...

journal_title：Biochemical and biophysical research communications

authors： Heller F,Zachoval R,Koelzer A,Nitschko H,Froesner GG

更新日期：2001-12-21 00:00:00

abstract：:Many organisms do not contain the necessary biochemical armoury to carry out the initial oxidative attack of many pollutant chemicals. In the present study, Acinetobacter sp. strain BD413 has been genetically engineered to express the cytochrome P450 xenobiotic-metabolising enzyme CYP105D1 from Streptomyces griseus th...

journal_title：Biochemical and biophysical research communications

authors： Lamb DC,Kelly DE,Masaphy S,Jones GL,Kelly SL

更新日期：2000-09-24 00:00:00

abstract：:Colorectal cancer is one of the leading causes of cancer-related deaths. Due to relapse after current therapy regimens, cancer stem cells (CSCs) are being studied to target this small tumor-initiating population. Anterior gradient 2 (AGR2), a disulfide isomerase protein, is a well-known pro-oncogenic/metastatic oncoge...

journal_title：Biochemical and biophysical research communications

authors： Dahal Lamichane B,Jung SY,Yun J,Kang S,Kim DY,Lamichane S,Kim YJ,Park JH,Jang WB,Ji ST,Dehua L,Ha JS,Kim YH,Kwon SM

更新日期：2019-08-06 00:00:00

abstract：:We have studied the importance of charge and hydrogen-bonding potential of the phosphodiester backbone for binding and cleavage by EcoRI restriction endonuclease. We used 12-mer oligodeoxynucleotide substrates with single substitutions of phosphates by chiral methylphosphonates at each position of the recognition sequ...

journal_title：Biochemical and biophysical research communications

authors： Rosati O,Srivastava TK,Katti SB,Alves J

更新日期：2002-07-05 00:00:00

abstract：:Type III polyketide synthases (PKSs) play an important role in biosynthesis of various plant secondary metabolites and plant adaptation to environmental stresses. Aquilaria sinensis (A. sinensis) is the main plant species for production of agarwood, little is known about its PKS family. In this study, AsCHS1 and two n...

journal_title：Biochemical and biophysical research communications

authors： Wang X,Zhang Z,Dong X,Feng Y,Liu X,Gao B,Wang J,Zhang L,Wang J,Shi S,Tu P

更新日期：2017-05-13 00:00:00

abstract：:Quite extraordinarily molybdenum is an essential element in life for the uptake of nitrogen from both nitrogen gas and nitrate, yet it is a relatively rare heavy trace element. It also functions in a few extremely important oxygen-atom transfer reactions at low redox potential. This review poses the question "Why does...

journal_title：Biochemical and biophysical research communications

authors： Williams RJ,Fraústo da Silva JJ

更新日期：2002-03-29 00:00:00

abstract：:The present study provides the first evidence for in vitro metabolic conversion of a 1,1-disubstituted hydrazine to the corresponding nitrosamine. The study shows that superoxide radical which is generated by NADPH-cytochrome c reductase is involved in the oxidation of 1,1-diphenylhydrazine to N-nitrosodiphenylamine c...

journal_title：Biochemical and biophysical research communications

authors： Tatsumi K,Kitamura S,Sumida M

更新日期：1984-02-14 00:00:00

abstract：:Alkaline elastase YaB, produced by alkalophilic Bacillus YaB, is an extracellular serine protease having 55% homology to subtilisin BPN' and thus could be called subtilisin YaB. It is synthesized as a 378-amino acid preproenzyme and secreted into the culture medium as a 265-amino acid mature protease. To examine if th...

journal_title：Biochemical and biophysical research communications

authors： Chang YC,Kadokura H,Yoda K,Yamasaki M

更新日期：1996-02-15 00:00:00

abstract：:The effects of isolated platelet surface membranes on DNA synthesis and proliferation of bovine coronary artery smooth muscle cells (SMC) were studied. Platelet membranes were very potent mitogens for SMC. The potency was about 10-fold higher than the maximum effects of platelet-derived growth factor-BB (PDGF). Platel...

journal_title：Biochemical and biophysical research communications

authors： Weber AA,Zucker TP,Schrör K

更新日期：1999-06-07 00:00:00

abstract：:Renin is produced from an inactive precursor, prorenin, through endoproteolytic cleavage at paired basic amino-acid residues. Using (35S)methionine-labeled prorenin, that was synthesized with Xenopus oocyte expression system, as a substrate, we have determined the tissue distribution and the nature of prorenin-convert...

journal_title：Biochemical and biophysical research communications

authors： Nakayama K,Kim WS,Hatsuzawa K,Hashiba K,Murakami K

更新日期：1989-01-31 00:00:00

abstract：:The I domains of CD11 are responsible for the binding of ligands and have a unique structure with 6-7 alpha helices and 6 beta sheets with interconnecting loops. To determine loops recognizing fibrinogen in CD11c I domain, five oligopeptides corresponding to CD11c loops were used to prevent fibrinogen binding to isola...

journal_title：Biochemical and biophysical research communications

authors： Choi J,Nham SU

更新日期：2002-04-05 00:00:00

abstract：:Earlier, we showed that antibodies specific for human serum albumin are able to bind to erythrocyte-associated albumin and inhibit complement mediated hemolysis. In the present study we determine if inhibition is occurring at the membrane attack phase of complement activation or at an earlier step. We show that althou...

journal_title：Biochemical and biophysical research communications

authors： Houle JJ,Hoffmann EM

更新日期：1994-04-15 00:00:00

abstract：:A cDNA for murine transcription factor S-II (Hirashima et al., J. Biol. Chem (1988) 263, 3858-3863) was inserted into a silkworm baculovirus vector and expressed in Bm-N cells, a cell line of Bombyx mori maintained in the laboratory. Recombinant S-II was purified from virus-infected cell extracts to near homogeneity b...

journal_title：Biochemical and biophysical research communications

authors： Hirashima S,Horikoshi N,Sekimizu K,Natori S

更新日期：1989-05-15 00:00:00

abstract：:Bovine brain smg p25A, a guanine nucleotide-binding protein with a Mr of about 25,000, bound specifically GTP, guanosine 5'-(3-O-thio)triphosphate (GTP gamma S) and GDP. The initial velocities of the binding of GTP gamma S to GDP-bound smg p25A and the dissociation of GDP from this protein increased by decreasing Mg2+...

journal_title：Biochemical and biophysical research communications

authors： Shoji I,Kikuchi A,Kuroda S,Takai Y

更新日期：1989-07-14 00:00:00

abstract：:Recently studies have revealed that CUEDC2, a CUE domain-containing protein, plays critical roles in many biological processes, such as cell cycle, inflammation and tumorigenesis. In this study, to further explore the function of CUEDC2, we performed affinity purification combined with mass spectrometry analysis to id...

journal_title：Biochemical and biophysical research communications

authors： Gong L,Wang CH,Huang YJ,Liu F,Li T,Dai J,Li AL,Zhou T,Xia Q,Chen L

更新日期：2014-04-25 00:00:00

abstract：:Glucocorticoids cause the delayed wound healing by suppressing inflammation that is required for wound healing process. Adipose tissue-derived mesenchymal stem cells (AT-MSCs) play an important role for wound healing by their cytokine productions including stromal derived factor 1 (SDF-1). However, it has not been cle...

journal_title：Biochemical and biophysical research communications

authors： Kato T,Khanh VC,Sato K,Takeuchi K,Carolina E,Yamashita T,Sugaya H,Yoshioka T,Mishima H,Ohneda O

更新日期：2017-11-18 00:00:00

abstract：:Glycosmis parva is a small shrub found in Thailand. Ethyl acetate (EtOAc) extract from its leaves has been shown to exert anticancer effects in vitro; however, the compound responsible for this activity has not been isolated and characterized. In this study, we demonstrate that arborinine, a major acridone alkaloid in...

journal_title：Biochemical and biophysical research communications

authors： Piboonprai K,Khumkhrong P,Khongkow M,Yata T,Ruangrungsi N,Chansriniyom C,Iempridee T

更新日期：2018-06-12 00:00:00

abstract：:Regulation of phospholipase D (PLD) activation by protein kinase C (PKC) was studied in membranes isolated from human promyelocytic leukemia HL60 cells. The activation of membrane-bound PLD by PKC partially purified from rat brain was most effectively induced with phorbol 12-myristate 13-acetate (PMA) and Ca2+ (1 micr...

journal_title：Biochemical and biophysical research communications

authors： Ohguchi K,Banno Y,Nakashima S,Nozawa Y

更新日期：1995-06-06 00:00:00

abstract：:This study was designed to investigate the protective effect of the autophagy signaling pathway against Mycobacterium tuberculosis infection in type II alveolar epithelial cells. An in vitro M. tuberculosis system was established using human A549 cells. Infection-induced changes in the expression of the autophagic mar...

journal_title：Biochemical and biophysical research communications

authors： Guo XG,Ji TX,Xia Y,Ma YY

更新日期：2013-03-08 00:00:00

abstract：:Centrin is an EF-hand calcium-binding protein found in microtubule organizing centers of organisms ranging from algae and yeast to man. Phosphorylation in the centrin C-terminal domain occurs in mitosis and is associated with alterations in contractile fibers. To obtain insight into the structural basis for the functi...

journal_title：Biochemical and biophysical research communications

authors： Meyn SM,Seda C,Campbell M,Weiss KL,Hu H,Pastrana-Rios B,Chazin WJ

更新日期：2006-03-31 00:00:00

abstract：:Activation of reactive oxygen and nitrogen species (RONS) by redox-active metal ions has been proposed to contribute to oxidative damage in inflamed tissues. Here, we report a dual-function anti-oxidant conjugate comprising an anti-inflammatory agent (5-aminosalicylic acid) and a chelator with potential as a superoxid...

journal_title：Biochemical and biophysical research communications

authors： Bailey MA,Ingram MJ,Naughton DP

更新日期：2004-05-14 00:00:00

abstract：:The ouabain-resistant and ouabain-sensitive alpha-subunit cRNAs in various molar ratios were injected into Xenopus oocytes together with cRNA for the beta-subunit. The ouabain-resistant ATPase activity, as well as ouabain-resistant Rb+ uptake, of the injected oocytes increased linearly with increasing the amount of cR...

journal_title：Biochemical and biophysical research communications

authors： Takeda K,Kawamura M

更新日期：2001-02-09 00:00:00

abstract：:We have isolated and characterized the cDNA encoding a novel protein designated DJ-1. DJ-1, sharing no significant homology with the sequences so far reported, did not show transactivation activity in the Gal4 recombinant system, but transformed mouse NIH3T3 cells by itself. Furthermore, DJ-1 showed a cooperative tran...

journal_title：Biochemical and biophysical research communications

authors： Nagakubo D,Taira T,Kitaura H,Ikeda M,Tamai K,Iguchi-Ariga SM,Ariga H

更新日期：1997-02-13 00:00:00

abstract：:We have used RT-PCR with degenerate transmembrane primers to clone members of the G-coupled protein receptor family from rat hypothalamic suprachiasmatic nuclei. We report here a novel clone, UHR-1, which encodes a candidate receptor that is most similar to the neuropeptide receptor family, including the tachykinins, ...

journal_title：Biochemical and biophysical research communications

authors： Welch SK,O'Hara BF,Kilduff TS,Heller HC

更新日期：1995-04-17 00:00:00

abstract：:Bacillus thuringiensis (Bt), considered a safe insecticide, produces insecticidal proteins named Cry during sporulation, which possess exceptional immunological properties. In this work using an immunohistochemical test we demonstrated that Cry1Ac protoxin (pCry1Ac) binds to the mucosal surface of the mouse small inte...

journal_title：Biochemical and biophysical research communications

authors： Vázquez-Padrón RI,Gonzáles-Cabrera J,García-Tovar C,Neri-Bazan L,Lopéz-Revilla R,Hernández M,Moreno-Fierro L,de la Riva GA

更新日期：2000-04-29 00:00:00

abstract：:Estrogen and androgen and their receptors play critical roles in physiological processes such as sexual differentiation and development. Using the available structural models for the human estrogen receptors alpha and beta and androgen receptor as templates, we designed in silico agonist and antagonist models of medak...

journal_title：Biochemical and biophysical research communications

authors： Cui J,Shen X,Yan Z,Zhao H,Nagahama Y

更新日期：2009-02-27 00:00:00

abstract：:Neural stem cells (NSCs) have the potential for differentiation into neurons known as a groundbreaking therapeutic solution for central nervous system (CNS) diseases. To resolve the therapeutic efficiency of NSCs, recent researchers have focused on the study on microRNA's role in CNS. Some micro RNAs have been reporte...

journal_title：Biochemical and biophysical research communications

authors： Song J,Cho KJ,Oh Y,Lee JE

更新日期：2015-07-10 00:00:00

abstract：:Recent studies indicate that galactoside-binding proteins may bind the poly-N-acetyllactosamine sequences of laminin. We questioned whether human galactoside-binding protein (hL-31) binds to laminin and whether cells that express hL-31 on their surface use it as a laminin receptor to promote cellular attachment. The d...

journal_title：Biochemical and biophysical research communications

authors： Ochieng J,Gerold M,Raz A

更新日期：1992-08-14 00:00:00