Abstract:
:The paper presents clinical observations on 1 233 persons with smallpox who were admitted to the Infectious Diseases Hospital, Calcutta, in 1973. The disease was of the modified type in 53 patients (4.3%), the ordinary type in 717 (58.2%), the flat type in 249 (20.2%), and the haemorrhagic type in 214 (17.3%). The fatality of these types of smallpox was found to be 5.7%, 26.8%, 88.4%, and 98.1%, respectively, and the overall case fatality was 50.7%. The haemorrhagic type was found mainly among older patients and affected males more often than females. The vaccination status of 1 218 patients was known. Of these, 901 (73.9%) were unvaccinated and had a fatality rate of 53.4%, whereas the 317 (26.1%) vaccinated patients had a fatality rate of 36.5%. Among the 201 haemorrhagic cases, 145 patients were unvaccinated (16.09% of the total number unvaccinated) and 56 (17.67%) had been vaccinated. Of 34 patients vaccinated during the incubation period, 19 (41.1%) died, whereas of 18 patients who had been vaccinated after the onset of fever, but before the appearance of rash, 9 (50%) died.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Mazumder DN,Mitra AC,Mukherjee MKsubject
Has Abstractpub_date
1975-01-01 00:00:00pages
301-6issue
3eissn
0042-9686issn
1564-0604journal_volume
52pub_type
杂志文章abstract:OBJECTIVE:To evaluate the cost-effectiveness of pulse oximetry--compared with no peri-operative monitoring--during surgery in low-income countries. METHODS:We considered the use of tabletop and portable, hand-held pulse oximeters among patients of any age undergoing major surgery in low-income countries. From earlier ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:10.2471/BLT.14.137315
更新日期:2014-12-01 00:00:00
abstract::The insecticide propoxur was applied as 2 non-overlapping bands approximately 1 m wide to the interior of houses in El Salvador once every 35 days for a period of 9 months. Air samples were collected from the interior of the houses once every seventh day during the entire period. In the study area, air temperatures re...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1974-01-01 00:00:00
abstract::As a result of extensive travel and temporary residence by people in areas where malaria is endemic, the disease is being reimported into countries from which it has been eradicated. Owing to the lack of experience of malaria on the part of present-day physicians and the atypical presentation of some forms of the dise...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1974-01-01 00:00:00
abstract::Previous investigations have shown that in the Lake Region of Sukumaland, Tanganyika, where Schistosoma haematobium is highly endemic, Bulinus (Physopsis) nasutus is responsible for the transmission of that schistosome in small, temporary rain pools. This area is one of low rainfall, and large artificial reservoirs ar...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1964-01-01 00:00:00
abstract::There is a need for additional data on the distribution of pneumococcal serotypes in developing countries. We report the use of a coagglutination (COA) and a latex agglutination (LA) test for serotyping Streptococcus pneumoniae which were evaluated using 114 clinical isolates in Vellore, India. In tests to serotype 30...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:To assess the effect of tobacco smoking on the outcome of tuberculosis treatment in Tbilisi, Georgia. METHODS:We conducted a prospective cohort study of adults with laboratory-confirmed tuberculosis from May 2011 to November 2013. History of tobacco smoking was collected using a standardized questionnaire ad...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.14.147439
更新日期:2015-06-01 00:00:00
abstract::Two, 30-cluster, retrospective surveys of deaths from neonatal tetanus in Indonesia were conducted during 1982. The first survey, in the city of Jakarta, identified 16 deaths from neonatal tetanus among 2310 live births, giving a mortality rate of 6.9 per 1000 live births. The second survey covered 19 of Indonesia's 2...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::The idea that malaria in South-East Asia is synonymous with adult malaria is questioned in this paper. In the Lao People's Democratic Republic, community-based malariometric data were collected in Savannakhet Province, which shares borders with Viet Nam in the east and Thailand in the west. The data indicate that ende...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,多中心研究
doi:
更新日期:1998-01-01 00:00:00
abstract::This paper summarizes recent thinking on stimulating industrial research and development (R&D) for neglected infectious diseases and argues that it is critical to enlarge the value of the market for medicines and vaccines through, for example, global purchase funds. The most important economic barriers to R&D are that...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::Schistosoma mansoni and Schistosoma haematobium are widely distributed throughout East Africa, each being transmitted by several intermediate hosts. It is feared that the increased use of irrigation, which is proposed in Tanganyika to expand agricultural productivity, will also increase the incidence and intensity of ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1965-01-01 00:00:00
abstract:OBJECTIVE:To determine whether vaccination against measles in a population with sustained high vaccination coverage and relatively low child mortality reduces overall child mortality. METHODS:In April and May 2000, a population-based, case-control study was conducted at Ballabgarh (an area in rural northern India). El...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:To determine paediatric blood sample volume limits that are consistent with physiological "minimal risk." METHODS:A literature review was performed to search for evidence concerning the adverse effects of blood sampling in children and for guidelines on sampling volume in paediatric research. The search incl...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:10.2471/BLT.10.080010
更新日期:2011-01-01 00:00:00
abstract::Among 1109 patients with bacteriologically confirmed El Tor cholera admitted to the San Lazaro Hospital, Manila, in 1969, 11 patients continued to excrete vibrios of the same biotype and serotype in stools for more than 1 week in spite of antibiotic treatment.The strains isolated from these patients all belonged to th...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1970-01-01 00:00:00
abstract:PROBLEM:As national antiretroviral treatment (ART) programmes scale-up, it is essential that information is complete, timely and accurate for site monitoring and national planning. The accuracy and completeness of reports independently compiled by ART facilities, however, is often not known. APPROACH:This study assess...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.07.044685
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:To increase case-finding of infection with human immunodeficiency virus (HIV) in Zambia and their referral to HIV care and treatment by supplementing existing client-initiated voluntary counselling and testing (VCT), the dominant mode of HIV testing in the country. METHODS:Lay counsellors offered provider-in...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.10.084442
更新日期:2011-05-01 00:00:00
abstract::The cross-reactivity of filarial heteroantigens, the non-availability of adult Wuchereria bancrofti for antigen extraction, and the lack of structural information on purified filarial heteroantigens make the serological diagnosis of W. bancrofti infection in man a difficult problem. The use of immune sera from cattle ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Division of Brucella strains into three species has long been based on differences in growth characteristics on certain dye-agar media and on variations in H(2)S production on liver agar slants. But certain workers believe these differences to be merely quantitative, such as are found between varieties of one species....
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1961-01-01 00:00:00
abstract::A taxonomic approach using cluster analysis and principal component analysis has grouped the countries of the world in eight clusters, in an initial attempt to propose a worldwide spatial classification based on the following health-related indicators: (a) those directly related to the health status of the population;...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::A new straightforward photometric method for the assay of the antimalarial drug chloroquine and its metabolites in urine is described. The method involves an ion-pair extraction procedure with dichloromethane using the acid-base indicator bromthymol blue as counter-ion. The ion pair formed with chloroquine in the orga...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::Dengue haemorrhagic fever/dengue shock syndrome (DHF/DSS) is an enigmatic and growing public health problem which is confined at present to countries of South-East Asia. Since 1956, over 350 000 patients have been hospitalized and nearly 12 000 deaths have been reported. Dengue viruses, a group of four flaviviruses, a...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Smallpox vaccinations were performed in a well-vaccinated prison population by multiple-pressure technique and by intradermal jet injection using serial dilutions of vaccine. A total of 140 subjects were divided into groups, and each group was vaccinated by the multiple-pressure technique or by jet injection using 1 o...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章
doi:
更新日期:1969-01-01 00:00:00
abstract::In 1995, the WHO Regional Office for Africa launched a logistics project to address the four main areas of immunization logistics: the cold chain, transport, vaccine supply and quality, and the safety of injections in the countries of the region. The impact of this logistic approach on immunization injection safety wa...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::Thiomersal-iodine-formalin (TIF) has been used as a faecal preservative in many prevalence surveys of intestinal helminths and protozoa. In helminth surveys, however, estimates of worm burden are no less essential than those of prevalence. Direct-smear and dilution egg-counting techniques, using fresh faeces, have bee...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1968-01-01 00:00:00
abstract::This paper is an attempt to relate modifications observed in general and infant mortality rates with the dynamic changes in transmission induced by malaria control measures. The observations indicated relationships between the efficacy of control and a decrease in mortality. The daily parasitological inoculation rate ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::The findings in a highly selected group of patients, such as those attending clinics or sanatoria, cannot be used as the basis for assessing the true prevalence of strains of Mycobacterium tuberculosis with acquired or primary resistance or of sensitive strains in a community. The present report describes the prevalen...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1968-01-01 00:00:00
abstract::Reported is an enzyme-linked immunosorbent assay (ELISA) that has been optimized and validated for the determination of chloroquine in urine or dried blood spots. The assay employs antisera raised in sheep to a chloroquine derivative conjugated to keyhole limpet haemocyanin and chloroquine conjugated to porcine thyrog...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:To ascertain the reliability of applying the WHO Cardiovascular Risk Management Package by non-physician health-care workers (NPHWs) in typical primary health-care settings. METHODS:Based on an a priori 80% agreement level between the NPHWs and the "expert" physicians (gold standard), 649 paired (matched) ap...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.06.032177
更新日期:2007-06-01 00:00:00
abstract::In the USA, the concept of an occupational health programme has grown steadily, and now embraces the total health of the worker. Elements of basic in-plant health programmes have been identified and patterns developed for successful operation.Today, health services in small plants still fall far short of optimal requi...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1955-01-01 00:00:00
abstract:OBJECTIVE:To determine the fraction of individuals with high total serum cholesterol who get diagnosed and effectively treated in eight high- and middle-income countries. METHODS:Using data from nationally representative health examination surveys conducted in 1998-2007, we studied a probability sample of 79 039 adult...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.10.079947
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:To identify the long-term patterns of drowning mortality in the state of Victoria, Australia, and to describe the historical context in which the decrease occurred. METHODS:We obtained data on drowning deaths and population statistics from the Australian Bureau of Statistics and its predecessors for the peri...
journal_title:Bulletin of the World Health Organization
pub_type: 历史文章,杂志文章
doi:10.2471/BLT.16.174425
更新日期:2017-03-01 00:00:00