ELISA in the diagnosis of Wuchereria bancrofti infection in man: a technique for reducing cross-reactivity.

Abstract:

:The cross-reactivity of filarial heteroantigens, the non-availability of adult Wuchereria bancrofti for antigen extraction, and the lack of structural information on purified filarial heteroantigens make the serological diagnosis of W. bancrofti infection in man a difficult problem. The use of immune sera from cattle infected with Setaria digitata when carrying out the enzyme-linked immunosorbent assay (ELISA) largely eliminated the cross-reactions with serum antibodies generally seen in subjects showing no evidence of W. bancrofti infection.

authors

Dissanayake S,Ismail MM

subject

Has Abstract

pub_date

1980-01-01 00:00:00

pages

655-7

issue

4

eissn

0042-9686

issn

1564-0604

journal_volume

58

pub_type

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