Abstract：
:This paper is a report on the first (serological) phase of a study organized by WHO in collaboration with the WHO International Reference Centre for Respiratory Virus Diseases other than Influenza in Bethesda, Md., USA, to define the viral etiology of severe respiratory infections in children, particularly in tropical areas. Paired sera from 528 children up to 5 years old admitted to hospital with severe respiratory illness of probable viral etiology were collected in 10 countries and sent frozen to the International Reference Centre, where standard complement-fixation tests were made for the following agents: parainfluenza virus types 1, 2 and 3, influenza virus types A and B, adenoviruses, respiratory syncytial virus, Mycoplasma pneumoniae, Coxiella burneti and psittacosis-ornithosis.Some 41% of paired sera showed rising antibody titres for one or more of these agents, multiple infections being observed in 8%. In most of the countries the pattern of infection was similar. RS virus was the most important respiratory tract pathogen of early life, particularly in the first year of life and in cases of bronchiolitis and pneumonia; the parainfluenza viruses were next in importance, particularly in cases of croup, but, in contra-distinction to RS virus infections, they were commoner in older children. Influenza, adenoviruses, and M. pneumoniae were of moderate importance, and C. burneti and the psittacosis-ornithosis agents were relatively rare. This pattern is similar to that which has been observed in temperate climates.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Chanock R,Chambon L,Chang W,Gonçalves Ferreira F,Gharpure P,Grant L,Hatem J,Imam I,Kalra S,Lim K,Madalengoitia J,Spence L,Teng P,Ferreira Wsubject
Has Abstractpub_date
1967-01-01 00:00:00pages
363-9issue
3eissn
0042-9686issn
1564-0604journal_volume
37pub_type
杂志文章abstract：:In a community study during a reference period of 1 year, 192 cases of jaundice were detected in an urban population of 69,440 in Alwar, Rajasthan. Detected by paramedics and confirmed by physicians, these cases gave an annual incidence of 2.76 (95% CI: 2.37-3.15) per 1000 population. At least one of these patients di...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：OBJECTIVE:To derive regional weight-for-age growth references to help optimize age-based dosing of antimalarials in Africa, the Americas, South-East Asia and the Western Pacific. METHODS:A weight-for-age database was constructed from pre-existing population-based anthropometric data obtained from household surveys and...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.14.139113
更新日期：2015-02-01 00:00:00
abstract：:Since 1990 the WHO Global Tuberculosis Programme (GTB) has promoted the revision of national tuberculosis programmes to strengthen the focus on directly observed treatment, short-course (DOTS) and close monitoring of treatment outcomes. GTB has encouraged in-depth evaluation of activities through a comprehensive progr...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：1997-01-01 00:00:00
abstract：OBJECTIVE:To assess the usefulness of the general framework of the smoking epidemic. METHODS:We use lung cancer mortality as an indicator for smoking intensity and employ an age-cohort model to accommodate the long-lasting and cumulative effects. RESULTS:Dutch males have higher risks than Danish males, but the risks ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:The deposit or precipitate formed after storage at -20 degrees C of allantoic fluids infected with influenza virus contains a considerable amount of the virus. It has been found that by treatment of this material, after thawing, with sodium chloride and subsequent purification of the treated fluid, all the virus origi...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1961-01-01 00:00:00
abstract：:This article provides a framework for the design of future eradication programmes so that the greatest benefit accrues to health systems development from the implementation of such programmes. The framework focuses on weak and fragile health systems and assumes that eradication leads to the cessation of the interventi...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:In the course of a research project on atherosclerosis, an international group of pathologists studied lesions in the aorta and coronary arteries obtained at autopsy from 3174 subjects from Czechoslovakia, Sweden and the USSR in an effort to determine what factors, recognizable in life, might be used to predict the pr...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1965-01-01 00:00:00
abstract：OBJECTIVE:To compare the efficacy of seven pyrethroid insecticides for impregnation of mosquito nets, six currently recommended by WHO and one candidate (bifenthrin), under laboratory conditions. METHODS:Tests were conducted using pyrethroid-susceptible and pyrethroid-resistant strains of Anopheles gambiae and Culex q...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：Objective:To determine the prevalence of and factors associated with dispensing antibiotics without a prescription in online and community pharmacies in China. Methods:We conducted a nationwide cross-sectional study of online and community pharmacies in 27 cities and counties in nine provinces in China (selected by mu...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.19.242370
更新日期：2020-07-01 00:00:00
abstract：:For several years after the First World War calcium oxide was the main compound used in the control of Oncomelania nosophora in Japan. This was generally replaced in 1944 by calcium cyanamide; since 1952 the prefectural authorities in areas of endemic bilharziasis have increasingly turned to the use of sodium pentachl...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1961-01-01 00:00:00
abstract：:There is a need to reassess the role of the trypanosomiases, both human and animal, in African ecology and economy. Withdrawal of control services from the Congo basin was followed by a resurgence of infection from ancient foci, many of them thought to have been extinguished. Successful elimination of Glossina in sava...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1969-01-01 00:00:00
abstract：:The serological identification of antibodies to human immunodeficiency virus (HIV) in blood is the most widely used method to diagnose HIV infection. Recently, however, the use of oral fluid samples for the detection of antibodies to HIV has been suggested as an alternative. This review describes some basic informatio...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：:A description is given of laboratory and field trials with a new molluscicide, Bayer 73. Following successful laboratory trials at one part per million, a river containing much vegetation and many semi-stagnant pools was treated at this dosage, the application resulting in a complete disappearance of snails and eggs f...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1960-01-01 00:00:00
abstract：:Twenty-six patients suffering from methylmercury poisoning were treated by different therapeutic regimes. Seven received penicillamine or N-acetyl-d-L-penicillamine, 10 were treated with dimercaprol sulfonate and 9, who could not be treated, were given a placebo and were used as controls. Penicillamine, N-acetyl-d-L-p...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：OBJECTIVE:To compare sentinel and population-based surveillance of the effect of seven-valent pneumococcal conjugate vaccine (PCV7), introduced in 2000, on the hospitalization of children aged under 5 years with invasive pneumococcal disease (IPD) in the United States of America. METHODS:Population surveillance data w...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.11.098178
更新日期：2012-08-01 00:00:00
abstract：:Since 1970, WHO has conducted a collaborative study on the use of "excess mortality" from respiratory diseases (that is, the number of deaths actually recorded in excess of the number expected on the basis of past seasonal experience) in order to assess in 13 different countries the severity of influenza epidemics. Th...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1973-01-01 00:00:00
abstract：:The author reviews the published findings on the carriage of Staphylococcus pyogenes var. aureus during the last two decades, dealing mainly with observations made in British Commonwealth countries, Scandinavia and the USA. The importance of the role played by staphylococcal carriers in the spread of infection both in...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1961-01-01 00:00:00
abstract：OBJECTIVE:To compare the effectiveness of oral ivermectin (IV) and two different modalities of topical benzyl benzoate (BB) for treating scabies in a community setting. METHODS:The trial included patients aged 5-65 years with scabies who attended the dermatology department at the Institut d'Hygiène Sociale in Dakar, S...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,随机对照试验
doi：10.2471/blt.08.052308
更新日期：2009-06-01 00:00:00
abstract：:A combination of chemotherapy and mollusciciding has been used in Khuzestan, south-west Iran, since 1966, to try to control urinary schistosomiasis. The total amount of molluscicide used each year varied between 702 and 3505 kg and between 287 and 1320 infected persons were detected and treated annually. The prevalenc...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:The dynamics of transmission of disease agents by vectors depends, in part, on the probability of host-vector contact, which can vary with fluctuations of both host and vector. As important as seasonal variations is 24-hour periodicity in activity. Periodicity in the landing of males and females of Aedes aegypti on ma...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1973-05-01 00:00:00
abstract：OBJECTIVE:To assess the consistent availability of basic surgical resources at selected facilities in seven countries. METHODS:In 2010-2014, we used a situational analysis tool to collect data at district and regional hospitals in Bangladesh (n = 14), the Plurinational State of Bolivia (n = 18), Ethiopia (n = 19), Gua...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.16.175885
更新日期：2017-06-01 00:00:00
abstract：:Villages associated with the Lesotho Highlands Development Agency were randomized with a bias in favour of larger villages, and children < 5 years of age from cluster-randomized households in these villages were chosen for the assessment of antibiotic resistance in pneumococci. Children of the same age group attending...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:The International Consortium in Psychiatric Epidemiology (ICPE) was established in 1998 by WHO to carry out cross-national comparative studies of the prevalences and correlates of mental disorders. This article describes the findings of ICPE surveys in seven countries in North America (Canada and USA), Latin America (...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:This month the World Health Assembly discusses the post-2015 global tuberculosis strategy and accompanying set of targets. Giovanni Battista Migliori tells Fiona Fleck how his institute - one of WHO's thousands of partners across the globe - can contribute in future to its implementation, once it is approved. ...
journal_title：Bulletin of the World Health Organization
pub_type： 面试,新闻
doi：10.2471/BLT.14.030514
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVE:To determine trends in mortality from respiratory disease in several areas of Latin America between 1998 and 2009. METHODS:The numbers of deaths attributed to respiratory disease between 1998 and 2009 were extracted from mortality data from Argentina, southern Brazil, Chile, Costa Rica, Ecuador, Mexico and P...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.12.116871
更新日期：2013-07-01 00:00:00
abstract：:In the course of a village-scale trial of fenthion, carried out in a village near Lagos, Nigeria, 40% fenthion water-dispersible powder was used at a 3.75% concentration. This was applied by Galeazzi "OM" sprayers with constant-pressure assemblies. The target concentration was 1.5 g/m(2). Filter-papers were placed on ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1963-01-01 00:00:00
abstract：:A method of assessing "atherosclerosis", if used according to certain rules, was shown in an earlier study to be capable of discriminating between groups of aortas or coronary arteries according to the quantity of certain defined lesions. It would not measure absolute amounts, but would show whether one group of speci...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1964-01-01 00:00:00
abstract：:The biological effects of tuberculin in an organism infected with tubercle bacilli are due to an unknown number of different substances, which are present in varying concentrations in different tuberculin preparations. Consequently, the response to tuberculin tests with various products is likely to vary with the biol...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1964-01-01 00:00:00
abstract：:Of 10 000 compounds tested for tissue schizontocidal activity in a Plasmodium gallinaceum-chick model, 157 were also tested in a definitive mouse test (DMT) and 277 in a rhesus monkey test (RMT). The results in the avian model were 78% and 55% in agreement with those of the DMT and RMT, respectively. This result is no...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Cholera, which had been spreading throughout the south-west Pacific in 1961, broke out in Hong Kong in August of that year. The outbreak lasted about six weeks, and recurred in 1962 and 1963; but whereas the 1961 outbreak resembled classical cholera, in the succeeding years the pattern changed. The disease, though sti...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1965-01-01 00:00:00
