Abstract:
:A method of assessing "atherosclerosis", if used according to certain rules, was shown in an earlier study to be capable of discriminating between groups of aortas or coronary arteries according to the quantity of certain defined lesions. It would not measure absolute amounts, but would show whether one group of specimens had more or less of the factor assessed than another and would indicate the statistical significance of this finding according to the number of specimens in each group.The method has now been applied to a study of material from six communities in three countries.This paper outlines how the rules of procedure were applied. Intra-observer and inter-observer calibration tests carried out in a routine manner during four "grading sessions" and inter-sessional tests are described.The discriminatory power in comparing groups of specimens from nearly 3000 subjects is calculated and shown according to artery (thoracic aorta, descending aorta, right coronary, left anterior descending coronary, left circumflex coronary) and type of lesion ("total amount of atherosclerosis", "fatty streak", "fibrous plaque", "complicated lesion" and "calcification"). Observations on "coronary stenosis" were also made. The discriminatory power of the method was calculated for this factor and, contrary to many expectations, was found to be of practical value.Definitions and general procedure are described in annexes.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
UEMURA K,STERNBY N,VANECEK R,VIHERT A,KAGAN Asubject
Has Abstractpub_date
1964-01-01 00:00:00pages
297-320eissn
0042-9686issn
1564-0604journal_volume
31pub_type
杂志文章abstract::This paper is a report on an attempt to study seasonal variations in endemic cholera in West Bengal by statistical analysis of monthly mortality records over a 21-year period. The annual death-rates have been calculated for each month in each district and the average of the seven lowest rates in each district is plott...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1961-01-01 00:00:00
abstract::It is likely that everyone will, at some time, suffer from a problem related to the musculoskeletal system, ranging from a very common problem such as osteoarthritis or back pain to severely disabling limb trauma or rheumatoid arthritis. Many musculoskeletal problems are chronic conditions. The most common symptoms ar...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:To determine whether integrating antiretroviral therapy (ART) into antenatal care (ANC) and maternal and child health (MCH) clinics could improve programmatic and patient outcomes. METHODS:The authors systematically searched PubMed, Embase, African Index Medicus and LiLACS for randomized controlled trials, p...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,meta分析,评审
doi:10.2471/BLT.12.107003
更新日期:2013-01-01 00:00:00
abstract::Strains of Vibrio cholerae-1156 from various parts of the world-were examined by standardized antibiotic sensitivity tests in one centre, to determine the global incidence of antibiotic resistance in this organism and to assess the extent to which differences in methods of sensitivity testing might be responsible for ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::In China, alcohol consumption is increasing faster than anywhere else in the world. A steady increase in alcohol production has also been observed in the country, together with a rise in alcohol-related harm. Despite these trends, China's policies on the sale and consumption of alcoholic beverages are weak compared wi...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.12.107318
更新日期:2013-04-01 00:00:00
abstract::Schistosoma mansoni and Schistosoma haematobium are widely distributed throughout East Africa, each being transmitted by several intermediate hosts. It is feared that the increased use of irrigation, which is proposed in Tanganyika to expand agricultural productivity, will also increase the incidence and intensity of ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1965-01-01 00:00:00
abstract::Perinatal, fetal and early neonatal mortality rates were determined in a population of 7392 babies born in hospitals in Pelotas (total population, 260 000) during 1982. These babies represented over 99% of all births in the city in that year. The perinatal mortality rate for singletons was 31.9 per 1000 total births, ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::There is considerable exigency to take all necessary steps to cure tuberculosis cases and prevent further emergence of drug-resistant tuberculosis. The most important of these steps is to ensure that the treatment, particularly of sputum smear-positive cases, is adequate and that patients adhere to their treatment by ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::A possible method for genetic control of insect vector species involves the use of translocation heterozygotes. The potential of single and double heterozygotes already available in Aedes aegypti has been investigated with computer simulations of release strategies. Such simulations indicate a possible role for transl...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1971-01-01 00:00:00
abstract::Recombinant proteins directed against the circumsporozoite (CS) protein of Plasmodium vivax were tested for safety, immunogenicity, and efficacy in Saimiri sciureus boliviensis monkeys. The monkeys were immunized 3 times with either alum or muramyl tripeptide as adjuvant, and were challenged with 10,000 sporozoites (P...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::This report from the Tuberculosis Chemotherapy Centre, Madras, summarizes the progress over a 5-year period of 193 patients with newly diagnosed, sputum-positive pulmonary tuberculosis who were admitted to a concurrent comparison of home and sanatorium treatment for one year with isoniazid plus PAS. Previous reports h...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1966-01-01 00:00:00
abstract:OBJECTIVE:To determine if educating caregivers in providing zinc supplements to infants < 6 months old with acute diarrhoea is effective in treating diarrhoea and preventing acute lower respiratory infections (ALRIs), and whether it leads to a decrease in the use of oral rehydration salts (ORS). METHODS:In this retros...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,随机对照试验
doi:10.2471/BLT.10.075986
更新日期:2010-10-01 00:00:00
abstract::In a community study during a reference period of 1 year, 192 cases of jaundice were detected in an urban population of 69,440 in Alwar, Rajasthan. Detected by paramedics and confirmed by physicians, these cases gave an annual incidence of 2.76 (95% CI: 2.37-3.15) per 1000 population. At least one of these patients di...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::When mice are immunized with radiation-attenuated sporozoites they are solidly protected against sporozoite challenge by an immune response that has been shown to require CD8+ lymphocytes in several strains of mice. The target of this CD8+ T-cell-dependent immunity has not been established. Immune BALB/c mice were sho...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::This article reviews the development of the WHO project on the histological classification of tumours, which has included the establishment of several collaborating centres and has involved more than 300 pathologists in over 50 countries. The project has resulted in the publication, over the last 14 years, of 25 volum...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::Health technology assessment (HTA) is the multidisciplinary study of the implications of the development, diffusion and use of health technologies. It supports health-policy decisions by providing a joint knowledge base for decision-makers. To increase its policy relevance, HTA tries to extend beyond effectiveness and...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.08.051078
更新日期:2008-08-01 00:00:00
abstract::To assess its potential applications in plague surveillance and control programmes, an enzyme-linked immunosorbent assay (ELISA) that captures the specific Yersinia pestis F1 antigen was used to determine the amounts of this antigen present in samples of blood and spleens from laboratory rats with acute plague, in the...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Reported are the results of a randomized, double-masked, placebo-controlled trial of annual ivermectin dosing in 34 rural communities, Kaduna State, northern Nigeria, where guinea savanna onchocerciasis is mesoendemic. A total of 939 individuals underwent Friedmann field analysis at the first examination and saw at le...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1997-01-01 00:00:00
abstract::The usefulness of a recently developed portable haemoglobinometer in primary health care was assessed in a survey of anaemia carried out in an isolated Indian community living in the jungles of northern Peru. This haemoglobinometer requires only one drop of blood to be added to a disposable cuvette without predilution...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::The single radial haemolysis reaction has been shown to be suitable for the quantitative assay of specific antibody to West Nile and Sindbis viruses. Only 5 mul of undiluted serum are needed for the test, which can be performed on crude preparations of antigen and without removal of nonspecific inhibitors. It is there...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::A very large private health sector exists in low-income countries. It consists of a great variety of providers and is used by a wide cross-section of the population. There are substantial concerns about the quality of care given, especially at the more informal end of the range of providers. This is particularly true ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::The evaluation of nutritional status using anthropometry has been widely employed in field studies and nutritional surveillance programmes. Two of the primary indicators used, weight-for-age and height-for-age, require accurate age information for proper assessments to be made. Three data sets on nutritional status we...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Dracontiasis is one of the most easily preventable of the tropical parasitic diseases, yet in India the infection is still present in large numbers of people and causes extreme degrees of morbidity and incapacitation.The 10 000 inhabitants of 4 villages in South India were interviewed and the prevalence of guinea-worm...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1969-04-01 00:00:00
abstract::The author reviews the agricultural use of night-soil, sewage, and sewage sludge from two points of view: the purely agricultural and the sanitary.Knowledge of the chemistry and bacteriology of human faecal matter is still rather scant, and much further work has to be done to find practical ways of digesting night-soi...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1954-01-01 00:00:00
abstract::In laboratory experiments sterile males produced by crossing member species of the Anopheles gambiae complex competed very successfully with normal males for normal females and the latter when mated with sterile males laid sterile eggs.A field trial was arranged in a small isolated village near Bobo-Dioulasso, Upper V...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1970-01-01 00:00:00
abstract:Problem:Slovenia's model of primary health care relied on reactive, episodic care and was ill-equipped to address the country's burden of disease dominated by noncommunicable diseases. Approach:The government has developed a multidisciplinary, community-based, prevention-oriented service delivery model for primary hea...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.19.239616
更新日期:2020-05-01 00:00:00
abstract::The Purchase price report released in August 2004 by the Global Fund to Fight AIDS, Tuberculosis, and Malaria (Global Fund) was the first publication of a significant amount of real transaction purchase data for antiretrovirals (ARVs). We did an observational study of the ARV transaction data in the Purchase price rep...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.05.025684
更新日期:2006-05-01 00:00:00
abstract::The immunizing potency of liquid BCG vaccine prepared by the Tween 80 method was compared with that of control vaccine prepared by the usual grinding method. The former vaccine revealed higher immunizing properties than the latter although its inoculation dose was only one-fifth as great.With sodium glutamate as adjuv...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1957-01-01 00:00:00
abstract::The author describes the design and operation of an automatic molluscicide dispenser for use in flowing water. The equipment, which consists basically of a measuring weir coupled to a float-activated siphon, was designed for simplicity, low cost, construction with commonly available materials, and operation by untrain...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1956-01-01 00:00:00
abstract::Evaluation of disease outcome is central to the assessment of tuberculosis (TB) control programmes. In the study reported in this article we examined the factors influencing the measurement of outcome, survival rates during and after treatment, smear conversion rates, and relapse rates for patients diagnosed with TB i...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00