Abstract：
:The serological identification of antibodies to human immunodeficiency virus (HIV) in blood is the most widely used method to diagnose HIV infection. Recently, however, the use of oral fluid samples for the detection of antibodies to HIV has been suggested as an alternative. This review describes some basic information about oral fluids, the application of these samples for HIV testing, and summarizes results from many of the studies performed using HIV tests with oral fluids. The fluids obtained from the oral cavity include saliva and crevicular fluid, and can be collected directly (by dribbling) or by using commercially available devices. The immunoglobulin content of oral fluids is similar to that of blood, but their levels are less. However, the use of an HIV IgG antibody capture assay (GAC ELISA) designed specifically for testing oral fluids, and certain routine HIV blood tests that have been optimized for use with oral fluids, has produced encouraging results. A number of studies, including several in developing countries, report that the sensitivities and specificities of these optimized tests lie in the range 95-100% and 98-100%, respectively. Also, the performance of the GAC ELISA was consistent and in general, excellent. The article identifies several issues that need to be addressed before a recommendation on the routine use of oral fluid samples for HIV antibody detection can be made.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Tamashiro H,Constantine NTsubject
Has Abstractpub_date
1994-01-01 00:00:00pages
135-43issue
1eissn
0042-9686issn
1564-0604journal_volume
72pub_type
杂志文章,评审abstract：:It is likely that everyone will, at some time, suffer from a problem related to the musculoskeletal system, ranging from a very common problem such as osteoarthritis or back pain to severely disabling limb trauma or rheumatoid arthritis. Many musculoskeletal problems are chronic conditions. The most common symptoms ar...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:Recombinant proteins directed against the circumsporozoite (CS) protein of Plasmodium vivax were tested for safety, immunogenicity, and efficacy in Saimiri sciureus boliviensis monkeys. The monkeys were immunized 3 times with either alum or muramyl tripeptide as adjuvant, and were challenged with 10,000 sporozoites (P...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Studies were conducted each month for one year to determine the cercarial-incubation periods of Schistosoma haematobium and Schistosoma bovis in Bulinus truncatus for different months of infection. The snails were kept in outdoor aquaria in order to simulate the natural temperature conditions in the endemic bilharzias...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1966-01-01 00:00:00
abstract：:The basic problem in the study of tick-borne virus diseases is to establish where the virus is maintained in nature. In general, this focus will be found where there are large and relatively stable populations of ticks, small rodents and insectivores. In the Tribec region the principal vector of tick-borne encephaliti...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1967-01-01 00:00:00
abstract：:Although none of the currently available methods of contraception can be considered ideal for use by adolescents, many come reasonably close. The present article reviews the relative benefits and risks associated with each method. Oral contraceptives (OCs) appear to bear few specific risks for adolescents. Pills co...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:Up-to-date information is given on the epidemiological situation of zoonotic visceral leishmaniasis (ZVL) in nine Mediterranean countries, and on drug regimens adopted in the management of ZVL patients in each country. Results of experimental and clinical trials on the efficacy and tolerability of liposomal amphoteric...
journal_title：Bulletin of the World Health Organization
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：1995-01-01 00:00:00
abstract：PROBLEM:In 1999, a tuberculosis (TB) crisis was declared in the Western Pacific Region. APPROACH:In response, WHO established the Stop TB Special Project, which sought to halve 2000 levels of TB prevalence and mortality by 2010 through first reaching the global 2005 TB targets. LOCAL SETTING:Particular issues in the ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/blt.06.038521
更新日期：2007-05-01 00:00:00
abstract：:The Haemosporidia, which comprise the malaria parasites, have probably evolved from Coccidia of the intestinal epithelium of the vertebrate host by adaptation first to some tissues of the internal organs and then to life in the circulating cells of the blood.The present opinion is that, among the malaria parasites of ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1965-01-01 00:00:00
abstract：:The author reviews the agricultural use of night-soil, sewage, and sewage sludge from two points of view: the purely agricultural and the sanitary.Knowledge of the chemistry and bacteriology of human faecal matter is still rather scant, and much further work has to be done to find practical ways of digesting night-soi...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1954-01-01 00:00:00
abstract：:The results of a WHO-assisted survey of the distribution of Q fever in 32 countries and an analysis of reports published to date indicate that Q fever exists in 51 countries on five continents. Q-fever infection was most often reported in man and the domestic ruminants, such as cattle, sheep, and goats.The disease was...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1955-01-01 00:00:00
abstract：:Toxorhynchites brevipalpis, a predator on larvae of Aedes aegypti and other mosquitos, was successfully colonized in the laboratory. At 25 degrees C, embryonic development was completed within 50 hours of oviposition, while larval and pupal development together took a further 27-41 days. The adult mosquitos mated in c...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1973-05-01 00:00:00
abstract：:The author describes the design and operation of an automatic molluscicide dispenser for use in flowing water. The equipment, which consists basically of a measuring weir coupled to a float-activated siphon, was designed for simplicity, low cost, construction with commonly available materials, and operation by untrain...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1956-01-01 00:00:00
abstract：:Between July 1966 and May 1972 the Vesicular Disease Laboratory, Center for Disease Control, Atlanta, Ga., USA, tested specimens from 849 suspected smallpox cases by at least 2 methods, electron microscopy and chick embryo chorioallantoic membrane (CAM) cultures. A smaller number of specimens was tested by each of 4 m...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1973-05-01 00:00:00
abstract：:As a result of extensive travel and temporary residence by people in areas where malaria is endemic, the disease is being reimported into countries from which it has been eradicated. Owing to the lack of experience of malaria on the part of present-day physicians and the atypical presentation of some forms of the dise...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1974-01-01 00:00:00
abstract：:Four points are made about globalization and health. First, economic integration is a powerful force for raising the incomes of poor countries. In the past 20 years several large developing countries have opened up to trade and investment, and they are growing well--faster than the rich countries. Second, there is no ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：OBJECTIVE:To document the inclusion of key medicines for children in national essential medicines lists (EMLs) and standard treatment guidelines, and to assess the availability and cost of these medicines in 14 countries in central Africa. METHODS:Surveys were conducted in 12 public and private sector medicine outlets...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/blt.08.053645
更新日期：2009-03-01 00:00:00
abstract：:The acute toxicity of most of the commonly used organophosphorus insecticides is essentially the same. A few compounds with low toxicity, such as malathion, have been developed but further efforts in that direction are needed. Most of the organophosphorus insecticides exert a generalized cholinergic action by inhibiti...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1971-01-01 00:00:00
abstract：OBJECTIVE:To perform a comprehensive assessment of maternal mortality in Argentina, the ultimate purpose being to strengthen the surveillance system and reorient reproductive health policies to prevent maternal deaths. METHODS:Our multicentre population-based study combining qualitative and quantitative methodologies ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,多中心研究
doi：10.2471/blt.06.032334
更新日期：2007-08-01 00:00:00
abstract：:Although no full-scale survey of the prevalence of bilharziasis in Swaziland has been carried out, examinations of schoolchildren have revealed S. mansoni infection rates of up to 49% in some areas, and S. haematobium infection rates ranging from 3% to 75%. The highest prevalence occurs in areas where there are thickl...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1958-01-01 00:00:00
abstract：:Perinatal, fetal and early neonatal mortality rates were determined in a population of 7392 babies born in hospitals in Pelotas (total population, 260 000) during 1982. These babies represented over 99% of all births in the city in that year. The perinatal mortality rate for singletons was 31.9 per 1000 total births, ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:In comparison with other rodents, the mastomys is unique as regards the patterns of neoplastic and non-neoplastic diseases that it develops, some of which may constitute suitable animal models for corresponding diseases of man. Among the spontaneous diseases commonly encountered in necropsies of 600 mastomys maintaine...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：:The development of several DDT-resistant strains of Anopheles atroparvus is described. They were selected by larval treatment only (RL), selection of larval and adult females (RLAF), and selection of adult females and males (RAFM). Their rate of DDT-resistance was measured in the larval and adult states (mainly in the...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1959-01-01 00:00:00
abstract：OBJECTIVE:To investigate the impact of violence against mothers on mortality risks for their offspring before 5 years of age in Nicaragua. METHODS:From a demographic database covering a random sample of urban and rural households in Le n, Nicaragua, we identified all live births among women aged 15-49 years. Cases wer...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:This report presents the results of a six-month survey of the nature and extent of venereal diseases in Turkey which was undertaken by the author, on behalf of WHO, at the request of the Turkish Government. The first part of the report outlines the present venereal-disease-control system and includes descriptions of t...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1954-01-01 00:00:00
abstract：:Administration of live influenza vaccine produces an asymptomatic immunizing infection of the respiratory tract with the appearance of antibodies in the secretions of the respiratory passages.Because of natural variation in the antigenic and biological properties of the influenza virus, new vaccines must be developed ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1969-01-01 00:00:00
abstract：:A meeting was held to outline a comprehensive research plan, based on recent advances in biomedical sciences, for the development of improved methods for the control of tuberculosis. Such a plan requires a stepwise approach. The meeting focused on the initial activities to be carried out and on setting priorities.In t...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:This account of the conduct of the Similium Control Scheme at Abuja, Northern Nigeria, over the period 1956-66 shows that, by larvicide treatment of some 160 km of rivers with DDT in the early wet season, the Simulium damnosum density has been reduced by about 90% of its precontrol level each year over an area of more...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1968-01-01 00:00:00
abstract：OBJECTIVE:To examine infant feeding intentions of HIV-infected and uninfected women and the appropriateness of their choices according to their home resources; and to determine their adherence to their intentions in the first postnatal week. METHODS:Feeding intentions of pregnant women were compared against four resou...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/blt.06.032441
更新日期：2007-04-01 00:00:00
abstract：:Immunization of non-pregnant women in rural Bangladesh with two doses of aluminium-adsorbed tetanus-diphtheria toxoids reduced neonatal mortality by one-third during a period of 9-32 months after vaccination. The reduction in mortality rate was attributable almost entirely to a 75% lower mortality rate among 4-14-day-...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:In Iran, microscopic examination of skin scrapings from 2202 individuals with clinically diagnosed cutaneous leishmaniasis (CL) lesions revealed the presence of amastigotes in 1123 cases (51.0%). Bacteriological examinations of the lesions indicated that 788 individuals (35.7%) were also infected with one or more path...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
