Abstract：
:A meeting was held to outline a comprehensive research plan, based on recent advances in biomedical sciences, for the development of improved methods for the control of tuberculosis. Such a plan requires a stepwise approach. The meeting focused on the initial activities to be carried out and on setting priorities.In the setting of priorities, the meeting considered not only feasibility and potential benefit of various studies but also activities already being undertaken and their funding. Thus, emphasis was put on the exploitation of new technological approaches, such as recombinant DNA technology, T-cell cloning and hybrid-cell methodology, and the production of monoclonal antibodies and immunoregulatory substances. The following subjects were proposed for targeted research: molecular biology, monoclonal antibodies, immunoregulation in human tuberculosis, experimental immunology of tuberculosis, and cloning of mycobacteria.A strategic plan has been drawn up to indicate the link between the initial activities and the ultimate goals of the programme. It was recommended that a comprehensive research programme on the immunology and molecular biology of tuberculosis should be established and, as funds become available, the programme should be advertised to the scientific community on a worldwide basis.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
subject
Has Abstractpub_date
1983-01-01 00:00:00pages
779-85issue
5eissn
0042-9686issn
1564-0604journal_volume
61pub_type
杂志文章abstract：:The acute toxicity of most of the commonly used organophosphorus insecticides is essentially the same. A few compounds with low toxicity, such as malathion, have been developed but further efforts in that direction are needed. Most of the organophosphorus insecticides exert a generalized cholinergic action by inhibiti...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1971-01-01 00:00:00
abstract：:Inherited resistance to anticoagulant rodenticides was discovered in populations of Rattus norvegicus about 14 years ago. Similar resistance has now been reported from several countries in north-western Europe and from the USA. In order to detect resistance and to control it effectively, basic data on the susceptibili...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1972-01-01 00:00:00
abstract：:Separation and concentration of parasitized erythrocytes from infected blood was achieved by centrifugation of a sample placed in a layer on top of a cushion of a Ficoll solution with a critical density. Pure suspensions of parasitized erythrocytes were obtained from Plasmodium berghei infected rodent blood, whereas r...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:There is considerable exigency to take all necessary steps to cure tuberculosis cases and prevent further emergence of drug-resistant tuberculosis. The most important of these steps is to ensure that the treatment, particularly of sputum smear-positive cases, is adequate and that patients adhere to their treatment by ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:The lack of a simple and reliable test for sulfonamides has created a problem because of the increasing use of these drugs in the chemotherapy of malaria. This paper describes a modification of the Bratton-Marshall technique, for which the reagents are easily obtainable and which can be carried out in simply equipped ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:A study was undertaken in Bangalore City, India, to find out whether people with chest symptoms, including tuberculosis patients, attend general health institutions or report directly to tuberculosis clinics. The attendance for one day at 19 general dispensaries was investigated. Of the total of 2506 eligible persons ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1970-01-01 00:00:00
abstract：:This paper reviews recent experimental evidence in support of inoculation with antirabies serum, the value of which, as a prophylactic measure, is compared with that of vaccine treatment alone. The author concludes that the chief advantages of combined antiserum-vaccine prophylaxis lie in the rapid treatment of cases ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1954-01-01 00:00:00
abstract：:Many global health institutions, including the World Health Organization, consider primary health care as the path towards achieving universal health coverage (UHC). However, there remain concerns about the feasibility and effectiveness of this approach in low-resource countries. Ethiopia has been implementing the pri...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.19.248328
更新日期：2020-12-01 00:00:00
abstract：:Strains of Vibrio cholerae-1156 from various parts of the world-were examined by standardized antibiotic sensitivity tests in one centre, to determine the global incidence of antibiotic resistance in this organism and to assess the extent to which differences in methods of sensitivity testing might be responsible for ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:The paper presents clinical observations on 1 233 persons with smallpox who were admitted to the Infectious Diseases Hospital, Calcutta, in 1973. The disease was of the modified type in 53 patients (4.3%), the ordinary type in 717 (58.2%), the flat type in 249 (20.2%), and the haemorrhagic type in 214 (17.3%). The fat...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：:New global public health institutions are increasingly emphasizing transparency in decision-making, developing-country ownership of projects and programmes, and merit- and performance-based funding. Such principles imply an institutional response to the challenge of bridging the "know-do gap", by basing decisions expl...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/blt.05.028704
更新日期：2006-08-01 00:00:00
abstract：OBJECTIVE:To determine the demographic and health impact of deploying health service nurses and volunteers to village locations with a view to scaling up results. METHODS:A four-celled plausibility trial was used for testing the impact of aligning community health services with the traditional social institutions that...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/blt.06.030064
更新日期：2006-12-01 00:00:00
abstract：OBJECTIVE:To document the prevalence, age-distribution, and risk factors for anaemia in Tanzanian children less than 5 years old, thereby assisting in the development of effective strategies for controlling anaemia. METHODS:Cluster sampling was used to identify 2417 households at random from four contiguous districts ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:The Haemosporidia, which comprise the malaria parasites, have probably evolved from Coccidia of the intestinal epithelium of the vertebrate host by adaptation first to some tissues of the internal organs and then to life in the circulating cells of the blood.The present opinion is that, among the malaria parasites of ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1965-01-01 00:00:00
abstract：OBJECTIVE:To compare the effectiveness of oral ivermectin (IV) and two different modalities of topical benzyl benzoate (BB) for treating scabies in a community setting. METHODS:The trial included patients aged 5-65 years with scabies who attended the dermatology department at the Institut d'Hygiène Sociale in Dakar, S...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,随机对照试验
doi：10.2471/blt.08.052308
更新日期：2009-06-01 00:00:00
abstract：:A national cross-sectional survey of the heights and weights of Kuwaiti preschool-age children of 0-5 years was conducted on a stratified multistage sample of 2554 subjects from high and low socioeconomic levels. The collected data were used to compare the nutritional status of these children with their American count...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Israel has faced the challenge presented by epidemic poliomyelitis by using different immunization strategies. In the 1950s, inactivated poliovirus vaccine (IPV) helped to reduce the total burden of the disease, but cases continued to occur. Introduction of oral poliovirus vaccine (OPV) in mid-1961 had a dramatic effe...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：:Since the first attempt at vaccination more than 200 years ago, debate has been ongoing about the relative benefits and risks. However, debate was overshadowed by the threat of crippling illness and death. Over the years, vaccination programs succeeded in its goals: eradication of smallpox, near eradication of polio,...
journal_title：Bulletin of the World Health Organization
pub_type： 评论,杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVE:To assess the effect of tobacco smoking on the outcome of tuberculosis treatment in Tbilisi, Georgia. METHODS:We conducted a prospective cohort study of adults with laboratory-confirmed tuberculosis from May 2011 to November 2013. History of tobacco smoking was collected using a standardized questionnaire ad...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.14.147439
更新日期：2015-06-01 00:00:00
abstract：OBJECTIVE:To assess government actions to improve the healthiness of food environments in New Zealand, based on the healthy food environment policy index. METHODS:A panel of 52 public health experts rated the extent of government implementation against international best practice for 42 indicators of food environment ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.14.145540
更新日期：2015-05-01 00:00:00
abstract：:The isolation of West Nile virus from the brain tissue of three children who died of encephalitis in Mysore and Kolar districts of Karnataka State, India, is reported. This is the first such report from India. The significance of these isolations with reference to the role of West Nile virus in encephalitis in childre...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:Comprehensive labelling forms a vital part of any steps to control the quality of commercially distributed diagnostic reagents. This Memorandum gives recommendations for such labelling. Specifications are given for the recommended minimum information to be given on the label attached to the immediate container of clin...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:Among 1109 patients with bacteriologically confirmed El Tor cholera admitted to the San Lazaro Hospital, Manila, in 1969, 11 patients continued to excrete vibrios of the same biotype and serotype in stools for more than 1 week in spite of antibiotic treatment.The strains isolated from these patients all belonged to th...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1970-01-01 00:00:00
abstract：:Acute respiratory infections (ARI) are a leading cause of childhood morbidity and mortality in Pakistan. The National ARI Control Programme was launched in 1989 in order to reduce the mortality attributed to pneumonia, and rationalize the use of drugs in the management of patients with ARI. WHO's standard ARI case man...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:In 1963 the World Health Organization established a system for the collection and distribution of information on viruses. By 1973 laboratories in 45 countries were participating in this scheme. The present study is an analysis of the reports on adenovirus, influenza viruses A, B, and C, parainfluenza virus, respirator...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1974-01-01 00:00:00
abstract：:Analysis of three years of data from a malaria clinic operated by the Indian Council of Medical Research (ICMR) in the Government Medical College Hospital in Jabalpur, central India, showed a high malaria prevalence among pregnant women, which was statistically highly significant (P < 0.0001) compared with the situati...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:Catalina Devandas Aguilar talks to Stephanie Cheng about the impact of the 2008 Convention on the Rights of Persons with Disabilities, the importance of listening to people living with disabilities and what United Nations agencies can do to support their further empowerment. ...
journal_title：Bulletin of the World Health Organization
pub_type： 面试,新闻
doi：10.2471/BLT.19.030119
更新日期：2019-01-01 00:00:00
abstract：:From the standpoint of nutritional needs, physiological maturation, and immunological safety the provision of foods other than breast milk before about four months of age is unnecessary and may also be harmful. On the other hand, many infants require some complementary feeding by about six months of age. There are a n...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:The frequent experience in the tropics of poor results of BCG vaccination is sometimes explained by a hypothetical interaction with "non-specific" tuberculin sensitivity. However, samples of data from five tropical countries, reported in this paper, demonstrate a slight, positive correlation between the individual tub...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1966-01-01 00:00:00
abstract：:While relapses following clinical cure of American cutaneous leishmaniasis are frequent, no test has been described until now to predict such relapses. A cohort of 318 American cutaneous leishmaniasis patients was followed up for two years after treatment with meglumine antimoniate, during which time 32 relapses occur...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
