Abstract：
:There is a need for additional data on the distribution of pneumococcal serotypes in developing countries. We report the use of a coagglutination (COA) and a latex agglutination (LA) test for serotyping Streptococcus pneumoniae which were evaluated using 114 clinical isolates in Vellore, India. In tests to serotype 30 fresh isolates of pneumococci from meningitis (8 isolates), bacteraemia/septicaemia (21 isolates) and peritonitis (1 isolate) cases, there was complete concordance among the three methods. An additional 20 isolates (11 from cerebrospinal fluid and 9 from blood cultures) were serotyped using both LA and COA, with full agreement between the results. With a further 30 isolates, there was 93% concordance for the COA types with serotypes assigned by a WHO reference laboratory. The COA and LA serotyping results were equivalent in accuracy to those obtained using quellung serotyping. Both these agglutination tests are rapid, valid, and relatively cheap, and with appropriate validation by reference laboratories they could be more widely used in developing countries to obtain local and regional data on pneumococcal serotype distribution.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Lalitha MK,Pai R,John TJ,Thomas K,Jesudason MV,Brahmadathan KN,Sridharan G,Steinhoff MCsubject
Has Abstractpub_date
1996-01-01 00:00:00pages
387-90issue
4eissn
0042-9686issn
1564-0604journal_volume
74pub_type
杂志文章abstract：Objective:To assess the outcomes of children diagnosed with hearing impairment 3 years earlier in terms of referral uptake, treatment received and satisfaction with this treatment, and social participation. Methods:We conducted a population-based longitudinal analysis of children with a hearing impairment in two rural...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.18.226241
更新日期：2019-10-01 00:00:00
abstract：OBJECTIVE:To estimate the burden of road traffic injuries and deaths for all road users and among different road user groups in Africa. METHODS:We searched MEDLINE, EMBASE, Global Health, Google Scholar, websites of African road safety agencies and organizations for registry- and population-based studies and reports o...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,meta分析,评审
doi：10.2471/BLT.15.163121
更新日期：2016-07-01 00:00:00
abstract：:Cardiovascular diseases are often found to be associated with certain physicochemical characteristics of the environment-namely, the hardness of the water and the types of rock and soil underlying the area. Areas supplied with soft water usually have higher cardiovascular death rates than do areas supplied with hard w...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1972-01-01 00:00:00
abstract：:Highly sensitive case definitions were first introduced by national poliomyelitis eradication programmes to avoid missing true cases of the disease, though false-positive diagnostic errors could still occur owing to low specificity. Extensive data from all 1620 cases of acute, flaccid paralysis reported in Brazil duri...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:In most countries of the world there is a shortage of nurses but nowhere is it so acute as in the developing world. With International Nursing Day on 12 May 2010, Kathryn Senior investigates. ...
journal_title：Bulletin of the World Health Organization
pub_type： 新闻
doi：10.2471/BLT.10.020510
更新日期：2010-05-01 00:00:00
abstract：:Many countries in Latin America and the Caribbean (LAC) are currently reforming their national health sectors and also implementing a comprehensive approach to reproductive health care. Three regional workshops to explore how health sector reform could improve reproductive health services have revealed the inherently ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：2000-01-01 00:00:00
abstract：:A study was undertaken in Bangalore City, India, to find out whether people with chest symptoms, including tuberculosis patients, attend general health institutions or report directly to tuberculosis clinics. The attendance for one day at 19 general dispensaries was investigated. Of the total of 2506 eligible persons ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1970-01-01 00:00:00
abstract：:Some time ago the WHO Expert Committee on Biological Standardization asked the National Institute for Medical Research, London, to consult with the WHO International Blood Group Reference Laboratory concerning the establishment of an international standard for albumin-potentiated anti-Rh(o) (anti-D) blood-typing serum...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1967-01-01 00:00:00
abstract：:To assess its potential applications in plague surveillance and control programmes, an enzyme-linked immunosorbent assay (ELISA) that captures the specific Yersinia pestis F1 antigen was used to determine the amounts of this antigen present in samples of blood and spleens from laboratory rats with acute plague, in the...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:A simple force-of-infection model for onchocerciasis has been developed for a study of the age-specific epidemiological trends during a period of vector control in the Onchocerciasis Control Programme in the Volta River basin area (OCP). The most important factors included in the model are the longevity of an infectio...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:In order to determine the effectiveness of anti-typhoid vaccines in man a controlled field trial, the first of its kind, was organized in 1954-60 in the town and district of Osijek, Yugoslavia. Heat-killed, phenol-preserved and alcohol-killed, alcohol-preserved anti-typhoid monovaccines were used, with phenolized dyse...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1962-01-01 00:00:00
abstract：:Histochemical staining methods for acid phosphatase were used to study the differences among microfilariae of various West African strains of Onchocerca volvulus in both forest and Sudan-savanna onchocerciasis zones. The results have shown statistically significant differences in the staining patterns of microfilarial...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：OBJECTIVE:To determine whether a complex community intervention in rural Zambia improved understanding of maternal health and increased use of maternal health-care services. METHODS:The intervention took place in six rural districts selected by the Zambian Ministry of Health. It involved community discussions on safe ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.13.122721
更新日期：2014-01-01 00:00:00
abstract：:A simple technique for achieving high yields of Plasmodium falciparum parasites on a continuous basis is described. The technique is applicable in any laboratory. The culture apparatus is also simple and inexpensive and allows multiple cultures to be run simultaneously. A total of approximately 1-2 x 10(9) parasites c...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:The source (species of origin), type, and subgroup (where applicable) of the immunoglobulin chain are indicated prior to the numbers of the first and last amino acid residues comprising the synthesized sequence (stated in parentheses), e.g., human gamma 1 (289-298) or rat epsilon (143-147). Square brackets indicate th...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Ten male subjects from a region of the state of Pará, Brazil, where malaria is endemic received a single oral dose of 1000 mg mefloquine. The plasma levels of the drug and of its metabolite, 2,8-bis(trifluoromethyl)-4-quinolinecarboxylic acid, were determined densitometrically on thin-layer chromatography plates. The ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:A study spanning 10 years indicates that the erythrocytic stages of malarial parasites can be stored indefinitely in the vapour phase of liquid nitrogen without significant loss of infectivity. The results also suggest that loss due to the recovery procedures exceeds any loss that may have occurred during freezing and...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:Measurements of spermatheca diameter and wing length were made on 8 East African mosquito populations comprising Anopheles merus and A. gambiae species A, species B, and the "Bwamba cytotype" (=species D). The results showed that, on average, the spermatheca in species A females is larger than in species B. In each of...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1972-01-01 00:00:00
abstract：:Acute respiratory infections (ARI) are a leading cause of childhood morbidity and mortality in Pakistan. The National ARI Control Programme was launched in 1989 in order to reduce the mortality attributed to pneumonia, and rationalize the use of drugs in the management of patients with ARI. WHO's standard ARI case man...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Hospital- and community-based studies were conducted in central Sudan to investigate the association between pesticide exposure and perinatal mortality. The cases were 197 stillbirths in the hospital and 36 perinatal deaths in the community; the controls were 812 liveborn, normal-birth-weight infants in the hospital, ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:In 1963 the World Health Organization established a system for the collection and distribution of information on viruses. By 1973 laboratories in 45 countries were participating in this scheme. The present study is an analysis of the reports on adenovirus, influenza viruses A, B, and C, parainfluenza virus, respirator...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1974-01-01 00:00:00
abstract：:Field trials of various molluscicides-notably sodium pentachlorophenate, copper sulfate and dinitro-o-cyclohexylphenol-were carried out in Brazil in order to test their effectiveness against the aquatic intermediate hosts of human bilharziasis. Sodium pentachlorophenate was found to be the most effective in relation t...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1958-01-01 00:00:00
abstract：:Chikungunya (CHIK) virus, harvested from infected BHK-21 cell cultures and highly purified by a method combining zinc acetate precipitation, Sephadex-Sepharose column chromatography, and sucrose density gradient centrifugation, was subjected to ultraviolet (UV) irradiation and treatment with formalin. Inactivation of ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1973-05-01 00:00:00
abstract：:Aortic and coronary atherosclerosis and the prevalence of coronary stenosis and thrombosis were studied in subjects who had died of fresh or recurrent myocardial infarction or had suffered from myocardial infarction in the past. In general, severe atherosclerosis of the coronary arteries with stenosis and calcificatio...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:Although trench fever appears to be endemic in many areas of the world, recognition of the disease has been handicapped by the difficulties of making a clinical diagnosis and the unavailability of a simple laboratory procedure to establish the etiology. The author describes a method for the in vitro cultivation of Ric...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1966-01-01 00:00:00
abstract：:Measurements of child growth have become the most accepted means of assessing the protein-calorie nutritional status of economically developing populations. International reference standards have been suggested for a number of body measurements, but there has been little evaluation of their applicability in South-East...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1971-01-01 00:00:00
abstract：:Catalina Devandas Aguilar talks to Stephanie Cheng about the impact of the 2008 Convention on the Rights of Persons with Disabilities, the importance of listening to people living with disabilities and what United Nations agencies can do to support their further empowerment. ...
journal_title：Bulletin of the World Health Organization
pub_type： 面试,新闻
doi：10.2471/BLT.19.030119
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:To examine the prevalence of multiple types of maltreatment (MTM), potentially confounding factors and associations with depression, anxiety and self-esteem among adolescents in Viet Nam. METHODS:In 2006 we conducted a cross-sectional survey of 2591 students (aged 12-18 years; 52.1% female) from randomly-sel...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.08.060061
更新日期：2010-01-01 00:00:00
abstract：:It remains unclear why there is such marked variation in the severity of the human immunodeficiency virus (HIV) epidemic between African countries. The prevalence of HIV infection has reached high levels in many parts of southern Africa but in most countries of West Africa the levels are much lower. Although there is ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：2001-01-01 00:00:00
abstract：:Despite the rising burden of noncommunicable diseases, access to quality decentralized noncommunicable disease services remain limited in many low- and middle-income countries. Here we describe the strategies we employed to drive the process from adaptation to national endorsement and implementation of the 2016 Botswa...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.18.221424
更新日期：2019-02-01 00:00:00
