Abstract：
:Some time ago the WHO Expert Committee on Biological Standardization asked the National Institute for Medical Research, London, to consult with the WHO International Blood Group Reference Laboratory concerning the establishment of an international standard for albumin-potentiated anti-Rh(o) (anti-D) blood-typing serum. This paper describes the collection and testing of sera, the removal of unwanted antibodies, the pooling of the sera and the distribution in equal amounts in 3350 ampoules, which were subsequently freeze-dried. The titres were determined by 29 laboratories in 21 countries by means of four methods-suspension in albumin, replacement with albumin, enzyme (papain) treatment and the anti-human-globulin test. On the basis of the results obtained, the material has been established as the International Standard for Anti-Rh(o) (Anti-D) Incomplete Blood-Typing Serum and the International Unit has been defined, with the agreement of the participants in the collaborative study, as the activity contained in 0.95 mg of the International Standard for Anti-Rh(o) (Anti-D) Incomplete Blood-Typing Serum.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Goldsmith KL,Mourant AE,Bangham DRsubject
Has Abstractpub_date
1967-01-01 00:00:00pages
435-45issue
3eissn
0042-9686issn
1564-0604journal_volume
36pub_type
杂志文章abstract：:Although Aëdes aegypti shows extensive physiological, bionomic and morphological variation in different populations, the genetic basis for this variation has never been determined. Genetic plasticity influences disease transmission, resistance to control measures, and breeding behaviour. Solutions to problems of publi...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1961-01-01 00:00:00
abstract：:Studying the susceptibility of 189 Neisseria meningitidis strains to penicillin, amoxicillin, cefotaxime, ceftriaxone, chloramphenicol and rifampicin by determination of minimum inhibitory concentrations (MICs) by agar dilution (reference method), E-test and disc diffusion method on Mueller-Hinton agar at 37 degrees C...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:It is often impossible to measure the reference standard of cardiorespiratory fitness (the maximum oxygen intake) directly, and there is thus a need for subsidiary standard procedures based on body responses to submaximal exercise. In order to reach agreement on such procedures, a recent international working party ha...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1968-01-01 00:00:00
abstract：OBJECTIVE:To determine whether home visits for neonatal care by community health workers can reduce infant and neonatal deaths and stillbirths in resource-limited settings. METHODS:We conducted a systematic review up to 2008 of controlled trials comparing various intervention packages, one of them being home visits fo...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,meta分析,评审
doi：10.2471/BLT.09.069369
更新日期：2010-09-01 00:00:00
abstract：:Malarial antibody levels were measured by the enzyme-linked immunosorbent assay (ELISA) in two West African populations, one exposed to intense malaria transmission and the other protected. The results reflected the transmission of maternal antibody and, in the unprotected population, the subsequent increase of the EL...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:The eradication of smallpox required a unique, fully collaborative international effort on the part of WHO and Member States. In the course of the programme, many lessons were learned in its organization, execution and evaluation which have implications for other international activities. Most important among these wa...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：1987-01-01 00:00:00
abstract：:Health interventions vary substantially in the degree of effort required to implement them. To some extent this is apparent in their financial cost, but the nature and availability of non-financial resources is often of similar importance. In particular, human resource requirements are frequently a major constraint. W...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：/S0042-96862005000400013
更新日期：2005-04-01 00:00:00
abstract：:Monoclonal antibody NYS4 recognizes a single 140 kDa antigen on the surface of Plasmodium yoelii sporozoites, an antigen which is distinct from the extensively characterized circumsporozoite (CS) protein. To more thoroughly characterize this additional surface component, a genomic expression library was screened with ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:An epidemic of sleeping sickness, which started in 1976 in a focus within the county of Luuka in Central Busoga, has spread to cover the three districts of Busoga and large parts of the neighbouring districts of Tororo and Mukono. Forty-three isolates of the subgenus Trypanozoon from Busoga and Tororo (27 from man, 9 ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:The authors describe some experiments carried out to determine the effect of moisture, temperature, and pressure on the suspensibility of DDT water-dispersible powders.It was found that the removal of moisture brought about a slight increase in suspensibility; that heating for one hour at temperatures below 70 degrees...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1959-01-01 00:00:00
abstract：:Lay health workers are key to achieving universal health-care coverage, therefore measuring worker attrition and identifying its determinants should be an integral part of any lay health worker programme. Both published and unpublished research on lay health workers has largely focused on the types of interventions th...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.11.087825
更新日期：2011-12-01 00:00:00
abstract：:Part 1 of this Memorandum appeared in Vol. 49, pages 81-91. Part 2 covers neoplasia of the bovine urinary bladder; tumours of unknown cause (including melanomas, osteosarcomas, mammary tumours, lymphosarcomas, mastocytomas, transmissible venereal tumours, and histiocytomas); and the applications of animal models in st...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1973-01-01 00:00:00
abstract：:A simple force-of-infection model for onchocerciasis has been developed for a study of the age-specific epidemiological trends during a period of vector control in the Onchocerciasis Control Programme in the Volta River basin area (OCP). The most important factors included in the model are the longevity of an infectio...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:The author examines in detail the symptomatology, diagnosis, and treatment of plague, and outlines the problem of the length of the incubation period.The clinical features commonly met with in all severely-affected plague patients, regardless of the primary localization of the infection, are described. The author then...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1953-01-01 00:00:00
abstract：:Mice infected with Schistosoma mansoni were given an intramuscular injection of a single 80 mg/kg dose of randomly tritiated hycanthone. The uptake of the drug in male and female worms, as well as its concentration in the red blood cells and plasma of the mice, was followed for a period of 24 hours.Blood and plasma dr...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1970-01-01 00:00:00
abstract：:It is likely that everyone will, at some time, suffer from a problem related to the musculoskeletal system, ranging from a very common problem such as osteoarthritis or back pain to severely disabling limb trauma or rheumatoid arthritis. Many musculoskeletal problems are chronic conditions. The most common symptoms ar...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:To characterize patent and proprietary medicine vendors and shops in Nigeria and to assess their ability to help improve access to high-quality, primary health-care services. METHODS:In 2013 and 2014, a census of patent and proprietary medicine shops in 16 states of Nigeria was carried out to determine: (i) ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.15.154666
更新日期：2016-04-01 00:00:00
abstract：:One of the hazards involved in the use of antibiotics in animal feeds is that it may lead to the development of bacterial drug-resistance. An analysis of the phenomenon shows that this possibility largely depends on the size of the bacterial populations involved and on the possibility of selective multiplication of th...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：1963-01-01 00:00:00
abstract：:At present there is no reliable test for use under field conditions for assessing cure in schistosomal infections. It had previously been found that in such infections the excretion of beta-glucuronidase in the urine is increased, but a test based on this fact would be impracticable in the field because of the need to...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1966-01-01 00:00:00
abstract：:In the Lamia Plain, Greece, 12 years after the cessation of DDT spraying, Anopheles sacharovi is still present in very high densities and appears to have the same biting habits and host preferences as previously. Mosquitos of this species are still resistant to DDT and dieldrin. ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1973-06-01 00:00:00
abstract：:The concept proposed by WHO of an essential drugs list that should comprise drugs corresponding to the health needs of the majority of the people has been embraced by countries, which have adapted it to their needs. In this study, the essential antibacterial drug lists of 16 countries chosen from the six WHO regions a...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:The efficacy of BCG vaccine in preventing the clinical manifestations of leprosy in a tuberculosis-free area of Papua New Guinea is reported. Between 1963 and 1966 a total of 5356 subjects, randomized to receive BCG or saline inoculations, were examined for leprosy before the vaccination and surveillance was continued...
journal_title：Bulletin of the World Health Organization
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1989-01-01 00:00:00
abstract：:As stocks of the first International Standard for Chorionic Gonadotrophin were running low, the WHO Expert Committee on Biological Standardization authorized the National Institute for Medical Research, London, in 1960 to proceed with arrangements to replace it. This paper describes the nature and handling of the prop...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1964-01-01 00:00:00
abstract：:This paper describes the organization of an epidemiological survey, carried out by the Lipid Centre of the Institute of Experimental Medicine in Leningrad, particularly the ways in which subjects were recruited. The different methods of recruitment resulted in a total population response of 78.14%. A time index is int...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：:Achieving universal health coverage (UHC) involves distributing resources, especially human resources for health (HRH), to match population needs. This paper explores the policy lessons on HRH from four countries that have achieved sustained improvements in UHC: Brazil, Ghana, Mexico and Thailand. Its purpose is to in...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.13.118729
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVE:To describe the adaptation and scaling-up of an intervention to improve the visual health of children in the Apurimac region, Peru. METHODS:In a pilot screening programme in 2009-2010, 26 schoolteachers were trained to detect and refer visual acuity problems in schoolchildren in one district in Apurimac. To ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.15.163634
更新日期：2016-09-01 00:00:00
abstract：:Registration of births, recording deaths by age, sex and cause, and calculating mortality levels and differentials are fundamental to evidence-based health policy, monitoring and evaluation. Yet few of the countries with the greatest need for these data have functioning systems to produce them despite legislation prov...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：/S0042-96862005000800015
更新日期：2005-08-01 00:00:00
abstract：OBJECTIVE:To determine the extent to which the community-directed approach used in onchocerciasis control in Africa could effectively and efficiently provide integrated delivery of other health interventions. METHODS:A three-year experimental study was undertaken in 35 health districts from 2005 to 2007 in seven resea...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.2471/BLT.09.069203
更新日期：2010-07-01 00:00:00
abstract：:New initiatives are aiming to reduce the global burden of schistosomiasis, mainly through the large-scale application of chemotherapy. To target chemotherapy effectively, rapid assessment procedures are needed for identifying high-risk communities that are foci for the disease. In this review, we examine the developme...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：Objective:To determine the prevalence of and factors associated with dispensing antibiotics without a prescription in online and community pharmacies in China. Methods:We conducted a nationwide cross-sectional study of online and community pharmacies in 27 cities and counties in nine provinces in China (selected by mu...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.19.242370
更新日期：2020-07-01 00:00:00
