The neural code for taste in the brain stem: response profiles.

Abstract:

:In the study of the neural code for taste, two theories have dominated the literature: the across neuron pattern (ANP), and the labeled line theories. Both of these theories are based on the observations that taste cells are multisensitive across a variety of different taste stimuli. Given a fixed array of taste stimuli, a cell's particular set of sensitivities defines its response profile. The characteristics of response profiles are the basis of both major theories of coding. In reviewing the literature, it is apparent that response profiles are an expression of a complex interplay of excitatory and inhibitory inputs that derive from cells with a wide variety of sensitivity patterns. These observations suggest that, in the absence of inhibition, taste cells might be potentially responsive to all taste stimuli. Several studies also suggest that response profiles can be influenced by the taste context, defined as the taste stimulus presented just before or simultaneously with another, under which they are recorded. A theory, called dynamic coding, was proposed to account for context dependency of taste response profiles. In this theory, those cells that are unaffected by taste context would provide the signal, i.e., the information-containing portion of the ANP, and those cells whose responses are context dependent would provide noise, i.e., less stimulus specific information. When singular taste stimuli are presented, noise cells would provide amplification of the signal, and when complex mixtures are presented, the responses of the noise cells would be suppressed (depending on the particular combination of tastants), and the ratio of signal to noise would be enhanced.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Di Lorenzo PM

doi

10.1016/s0031-9384(00)00191-8

subject

Has Abstract

pub_date

2000-04-01 00:00:00

pages

87-96

issue

1-2

eissn

0031-9384

issn

1873-507X

pii

S0031-9384(00)00191-8

journal_volume

69

pub_type

信件,评审
  • Effects of septal lesions on shock thresholds in weanling male and female rats.

    abstract::Twenty-four-day old weanling male and female rats were either lesioned in the septal area, gonadectomized, lesioned and gonadectomized, or untreated. Tests for reactivity to electric shock were conducted at 26 and at 40 days of age. Neither males nor females showed any effect of the lesions are measured by flinch and ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(77)90046-4

    authors: Stewart J,Atkinson S,Cygan D

    更新日期:1977-11-01 00:00:00

  • Conditioned taste aversion to saccharin induced by 2, 4, 5-trichlorophenoxyacetic acid in albino rats.

    abstract::Four groups of Wistar rats were exposed either to saccharin + 2,4,5-T (taste-aversion group, T-A), saccharin + oil vehicle (taste-aversion control, T-A C), water + 2,4,5-T (enhanced neophobia, E-N), or water + oil (neophobia, N). Rats in the T-A group evidenced a marked aversion to saccharin in 3 consecutive preferenc...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(77)90174-3

    authors: Sjödén PO,Archer T

    更新日期:1977-07-01 00:00:00

  • The effects of small but abrupt change in temperature on the behavior of larval zebrafish.

    abstract::The zebrafish has become increasingly utilized in behavioral neuroscience, psychopharmacology, and behavior genetics research. However, little attention has been paid to the potential effects of environmental conditions fish are exposed to before and during behavioral testing. One such important factor is temperature,...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2020.113169

    authors: Abozaid A,Tsang B,Gerlai R

    更新日期:2020-12-01 00:00:00

  • Brood patch innervation and its role in the onset of incubation in the turkey hen.

    abstract::The source of innervation to the brood patch in turkey hens was determined by recording the electrophysiological activity of cutaneous nerves while manually stimulating various regions of the skin. The entire area of the brood patch was innervated by eight nerves, arising from thoracic vertebra 3 to synsacrothoracic v...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(91)90067-x

    authors: Book CM,Millam JR,Guinan MJ,Kitchell RL

    更新日期:1991-08-01 00:00:00

  • Long- and short-term habituation of acoustic startle is not frequency specific in the rat.

    abstract::Two experiments examined the frequency specificity of habituation of the acoustic startle response in the rat. Following the long-term habituation of startle to one of two pure tone stimuli in Experiment 1, animals were presented with the other stimulus. Startle response asymptotes were unaffected by this change in st...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(97)00512-x

    authors: Jordan WP,Poore LH

    更新日期:1998-02-15 00:00:00

  • Sex differences in the programming effects of prenatal stress on psychopathology and stress responses: an evolutionary perspective.

    abstract::There is strong evidence from animal studies that prenatal stress has different effects on male and female offspring. In general, although not always, prenatal stress increases anxiety, depression and stress responses, both hypothalamic-pituitary-adrenal and cardiovascular, in female offspring rather than in male. Mal...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.physbeh.2012.02.011

    authors: Glover V,Hill J

    更新日期:2012-07-16 00:00:00

  • Morphine and dextrorphan lose antinociceptive activity but exhibit an antispastic action in chronic spinal rats.

    abstract::Within 3-4 weeks after spinal transection, morphine-induced antinociception, assessed with the tail flick reflex in rats, is profoundly reduced. The cause of this decrement is unknown. The present studies were conducted to determine whether this phenomenon reflects a general loss in opiate activity or a selective decl...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(97)00240-0

    authors: Advokat C,Mosser H,Hutchinson K

    更新日期:1997-10-01 00:00:00

  • Long-term dietary restriction influences plasma ghrelin and GOAT mRNA level in rats.

    abstract::The objective of this study was to examine the effect of chronic dietary restriction on the physical characteristics of the intestine and gut-derived satiety hormone production. Male Wistar rats (8 weeks) were randomized to ad libitum (AL) or 35% dietary restriction (DR) for 5 months. At the end of the study, physical...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2010.01.034

    authors: Reimer RA,Maurer AD,Lau DC,Auer RN

    更新日期:2010-04-19 00:00:00

  • Food intake, body weight and lordosis in male and female mongolian gerbils: effects of ovarian steroids.

    abstract::The effects of gonadectomy and ovarian hormone treatment on food intake, body weight, and lordosis in male and female Mongolian gerbils were examined. In female gerbils, a significant decrease in food intake and body weight was observed after ovariectomy, with estradiol benzoate (1, 10, or 100 micrograms/day) increasi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(85)90410-x

    authors: Raible LH,Gorzalka BB

    更新日期:1985-11-01 00:00:00

  • Early development in mice. IV: Quantity and gross composition of milk in five inbred strains.

    abstract::An analysis of the gross composition of milk in five inbred strains of mice (NZB, CBA/H, BALB/c, C57BL/6, XLII) was conducted for two different days during the lactating period (6th and 9th day after parturition). The quantity of milk and the concentration of proteins, lactose and lipids were measured. Results show a ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(87)90027-8

    authors: Ragueneau S

    更新日期:1987-01-01 00:00:00

  • Effects of repeated stress on plasma arginine levels in young and old rats.

    abstract::The effect of age and recurring stress responses on endogenous plasma arginine (ARG) concentrations were determined. Blood from catheterized young (3 months) and old (24 months) were used to ascertain the plasma concentrations of ARG under baseline conditions, during a 30-min immobilization experience and during a 3.5...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90083-r

    authors: Milakofsky L,Harris N,Vogel WH

    更新日期:1993-10-01 00:00:00

  • The use of hypothermia in surgical pinealectomy of the neonate rat.

    abstract::A technique is described in which rat pups (5-7 days old) are induced into a state of suspended animation by placing them in the freezing compartment of a refrigerator at -20 degrees C for 8-10 minutes. This induces cessation of respiration and heart beat for 12-15 minutes. Surgical pinealectomy is undertaken during t...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(89)90088-7

    authors: Cairncross KD,Parks AA,Everitt AV,Destefanis P,Maxwell CA

    更新日期:1989-03-01 00:00:00

  • Daily fluctuation of urine serotonin and cortisol in healthy shelter dogs and influence of intraspecific social exposure.

    abstract::The aim of this study was to evaluate the effects of intraspecific social exposure (socialization vs rest) and habituation factors on the levels of urinary serotonin and cortisol [corrected respectively for creatinine to give the serotonin-creatinine ratio (5-HT/Cr) and cortisol-creatinine ratio (C/Cr)] and how they f...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2019.03.016

    authors: Alberghina D,Piccione G,Pumilia G,Gioè M,Rizzo M,Raffo P,Panzera M

    更新日期:2019-07-01 00:00:00

  • Scent-marking and sexual activity may reflect social hierarchy among group-living male Mongolian gerbils (Meriones unguiculatus).

    abstract::Social hierarchy plays an important role in the lives of gregarious species. We investigated how social hierarchy between male Mongolian gerbils (Meriones unguiculatus) housed together before sexual maturity affected their scent-marking behavior, endocrine status and physical traits as adults. The social rank between ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2006.08.001

    authors: Shimozuru M,Kikusui T,Takeuchi Y,Mori Y

    更新日期:2006-12-30 00:00:00

  • Aerobic exercise with blood flow restriction affects mood state in a similar fashion to high intensity interval exercise.

    abstract::We investigated the acute effects of aerobic exercise with blood flow restriction (BFR) on mood state in American football athletes. Twenty-two male American football athletes were randomly assigned to three experimental conditions: 1) aerobic exercise (AE: 40% VO2max), 2) aerobic exercise with BRF (AE + BFR: 40% VO2 ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.physbeh.2019.112677

    authors: da Silva JCG,Silva KF,Domingos-Gomes JR,Batista GR,da Silva Freitas ED,Torres VBC,do Socorro Cirilo-Sousa M

    更新日期:2019-11-01 00:00:00

  • Human interaction and cortisol: can human contact reduce stress for shelter dogs?

    abstract::Animal shelters are an extremely stressful environment for a dog, most specifically due to social isolation and novel surroundings. The stress response of dogs housed in this environment may be alleviated through human interaction shortly after arrival. During their second day in a public animal shelter, adult stray d...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.physbeh.2005.12.001

    authors: Coppola CL,Grandin T,Enns RM

    更新日期:2006-03-30 00:00:00

  • Age differences in the controls of ring doves' pecking.

    abstract::Three experiments investigated the endogenous and exogenous controls of ring dove pecking. Experiment 1 confirmed that deprivation modulates adult pecking although nondeprived subjects peak at high levels. Experiment 2 determined that the level of pecking in nondeprived birds is modulated by exogenous cues such as the...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90334-c

    authors: Iskrant KR,Balsam PD

    更新日期:1993-12-01 00:00:00

  • Maximal exercise and acute mood response in women.

    abstract::The present study was designed to characterize and assess the reliability of acute mood responses to maximal exercise in women. All subjects (N = 22; age = 45 +/- 2.5 yr; BMI = 24.3 +/- 0.9 kg/m2) participated in two maximal walking tests spaced approximately one month apart. The abbreviated Profile of Mood States (PO...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(94)00195-b

    authors: Pronk NP,Crouse SF,Rohack JJ

    更新日期:1995-01-01 00:00:00

  • The effect of feeding on defecation behaviour in pigs.

    abstract::The effect of eating on defecation behaviour was investigated in four 20-30 kg pigs. Rectal distention stimulation was performed pre- and postprandially at 10 cm from the anus with a 5 cm latex balloon. Volume was increased in steps of 10 ml up to 200 ml of air or until balloon defecation. Dependent measures were volu...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(92)90190-d

    authors: Musial F,Crowell MD,French AW

    更新日期:1992-03-01 00:00:00

  • Sex differences in HPA axis activity in response to a meal.

    abstract:BACKGROUND:Sex may influence the relationship between HPA axis functioning and obesity. This has been suggested to be due to sex-specific differences in body composition, body fat distribution and psychological variables. Age and the use of oral contraceptives may also influence the relationship between HPA axis functi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2012.02.016

    authors: Martens EA,Lemmens SG,Adam TC,Westerterp-Plantenga MS

    更新日期:2012-05-15 00:00:00

  • Effects of early postnatal gonadal steroids on extinction of a continuously food-rewarded running response.

    abstract::In the present work the existence of sex differences (Experiment 1) on the acquisition and extinction of a continuously reinforced response in a short and narrow runway (100 x 9 x 10 cm) were investigated. In addition to the investigation of the basic sex differences in Experiment 1, the effect of postpuberal gonadect...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(91)90230-l

    authors: Enriquez P,Calés JM,Sánchez-Santed F,Guillamón A

    更新日期:1991-01-01 00:00:00

  • Water adulteration with citric acid: effects on drinking and responsivity to regulatory challenges.

    abstract::Rats with permanent access to a water supply adulterated with citric acid (CA) displayed persistent reductions in fluid intake and fluid/food ratios; and at appropriate concentrations of CA, they also exhibited lowered body weights and drinking deficits after fluid deprivation and after hypertonic NaCl injections. Unl...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(86)90025-9

    authors: Watson PJ,Beatey S,Wagner F,Stahl T

    更新日期:1986-01-01 00:00:00

  • Of mice and mazes: similarities between mice and rats on dry land but not water mazes.

    abstract::Mice are impaired relative to rats in place and matching-to-place learning when tests are given in a swimming pool. The rat advantage may stem from a superior spatial ability or from adaptation to a niche that has prepared them for competency in the water. In the present study, mice (C57BL/6) were compared with rats (...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(96)00176-x

    authors: Whishaw IQ,Tomie J

    更新日期:1996-11-01 00:00:00

  • Schisantherin A recovers Aβ-induced neurodegeneration with cognitive decline in mice.

    abstract::Schisantherin A (STA) is a main bioactive lignan isolated from Schisandra chinensis (Turcz.) Baill., which has been widely used as a tonic in traditional Chinese medicine for many years. Lots of studies have reported that STA exhibited anti-inflammatory and antioxidant effects. This paper was designed to investigate t...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2014.04.046

    authors: Li X,Zhao X,Xu X,Mao X,Liu Z,Li H,Guo L,Bi K,Jia Y

    更新日期:2014-06-10 00:00:00

  • Genetic differences in female house mice in aggressive response to sex steroid hormone treatment.

    abstract::Male mice, genetically selected for aggression, characterized by short attack latency (SAL) or long attack latency (LAL), differ on several testosterone (T)-related parameters during ontogeny and adult age. The variation in aggressive behavior at adult age may be due to differences in degree of androgenization prenata...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90299-u

    authors: Compaan JC,van Wattum G,de Ruiter AJ,van Oortmerssen GA,Koolhaas JM,Bohus B

    更新日期:1993-11-01 00:00:00

  • The effect of odours on stimulated parotid salivary flow in humans.

    abstract::We have previously shown that smell has no effect on resting parotid salivary flow in humans. In this study we investigated the effect of two odours on unilateral parotid salivary flow stimulated by either mastication or mastication with gustation. Neither odour stimulated flow above that elicited by either masticatio...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(92)90470-m

    authors: Lee VM,Linden RW

    更新日期:1992-12-01 00:00:00

  • Behaviors of rats with insidious, multifocal brain damage induced by seizures following single peripheral injections of lithium and pilocarpine.

    abstract::Several domains of behavior were measured in rats (n = 465) 10 days to 100 days after induction of limbic seizures by a single subcutaneous injection of lithium and pilocarpine. These rats displayed enhanced intragroup aggression but normal muricide; gustatory neophobia and conditioned taste aversion were virtually el...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90261-d

    authors: Persinger MA,Bureau YR,Kostakos M,Peredery O,Falter H

    更新日期:1993-05-01 00:00:00

  • Opioid mechanisms that mediate the palatability of and appetite for salt in sodium replete and deficient states.

    abstract::Sodium deficiency reliably produces a robust intake of saline in rats, which is associated with an increased preference for sodium solutions at hypertonic concentrations that would normally be avoided. The mechanisms underlying the shift to an increased preference for sodium in the deficient state are not well underst...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2012.01.019

    authors: Na ES,Morris MJ,Johnson AK

    更新日期:2012-05-15 00:00:00

  • Effect of chronic insulin administration on food intake and body weight in rats.

    abstract::Insulin was chronically administered to rats to determine its effect on the daily changes in food intake and body weight. Animals received regular insulin via 14-day osmotic minipumps in doses of 0.0, 0.5, 1.0, 3.0, and 5.0 IU/day treated either with (+GLU) or without glutamic acid (-GLU). Previous studies have shown ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(91)90021-f

    authors: Destefano MB,Stern JS,Castonguay TW

    更新日期:1991-10-01 00:00:00

  • Incubation temperature and satiety influence general locomotor and exploratory behaviors in the common snapping turtle (Chelydra serpentina).

    abstract::Temperature during embryogenesis determines sex and has been shown to influence other physiological traits in reptiles. The common snapping turtle (Chelydra serpentina) is an ideal model for testing how temperature impacts behavior in species that display temperature-dependent sex determination. Behavioral assays are ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2020.112875

    authors: Miller S,Derenne A,Ellis-Felege S,Rhen T

    更新日期:2020-06-01 00:00:00