ATR-FTIR spectroscopic investigation of imipenem-susceptible and -resistant Pseudomonas aeruginosa isogenic strains.

abstract：:Successful seed germination depends on the rapid repair of cell membrane damaged by dry storage. However, little is known about the reorganization of lipids during this process. In this study, the changes of intracellular redox environment, cell membrane integrity, lipid composition, and expression of genes related to...

journal_title：Biochemical and biophysical research communications

authors： Lin YX,Xin X,Yin GK,He JJ,Zhou YC,Chen JY,Lu XX

更新日期：2019-07-23 00:00:00

abstract：:It has been shown that the protein serine/threonine phosphatase type 2A alpha catalytic subunit (PP2A alpha) has a mutation consisting of a glycine substitution for cysteine at 269 in the okadaic acid resistant variant of CHO cells, and that the mutant protein is resistant to okadaic acid (Shima, H. et al. Proc. Natl....

journal_title：Biochemical and biophysical research communications

authors： Kaneko S,Shima H,Amagasa T,Takagi M,Sugimura T,Nagao M

更新日期：1995-09-14 00:00:00

abstract：:Hepatocyte expression of inducible nitric oxide synthase (iNOS) is initiated by the presence of pro-inflammatory cytokines, such as interleukin-1beta (IL-1). In the presence of oxidative stress, IL-1beta mediated hepatocyte iNOS expression and NO synthesis are significantly increased. To determine the underlying molec...

journal_title：Biochemical and biophysical research communications

authors： Kuo PC,Abe KY,Schroeder RA

更新日期：1997-05-19 00:00:00

abstract：:High level of palmitate is associated with metabolic disorders. We recently showed that enhanced level of S-palmitoylated cytosolic thioredoxin (Trx1) in mouse liver was new characteristic feature of insulin resistance. However, our understanding of the effect of S-palmitoylation on Trx1 is limited, and the tissue spe...

journal_title：Biochemical and biophysical research communications

authors： Xu Z,Zhong L

更新日期：2015-05-15 00:00:00

abstract：:The radiation inactivation method was applied to brush border membrane vesicles from rat kidney, in order to estimate the molecular size of the Na+-H+ antiporter. Sodium influx (1mM) driven by an acid intravesicular pH was unaffected by the high osmolarity of the cryoprotective solution. Initial rate of influx was est...

journal_title：Biochemical and biophysical research communications

authors： Béliveau R,Demeule M,Potier M

更新日期：1988-04-15 00:00:00

abstract：:The distribution of SQSC1 mRNA in tissues of squid Loligo bleekeri was studied by the blot hybridization method. The complete cDNA for the coding region of SQSC1, the invertebrate putative sodium channel, was prepared from squid optic lobe (Sato and Matsumoto, Biochem. Biophys. Res. Comm. 186, 61-68, 1992). Transcript...

journal_title：Biochemical and biophysical research communications

authors： Sato C,Hirota K,Matsumoto G

更新日期：1995-01-26 00:00:00

abstract：:Fut8 (α1,6-Fucosyltransferase) heterozygous knock-out (Fut8(+/-)) mice had an increased influx of inflammatory cells into the lungs, and this was associated with an up-regulation of matrix metalloproteinases, MMP-2 and MMP-9, after treatment with porcine pancreatic elastase (PPE), exhibiting an emphysema-prone phenoty...

journal_title：Biochemical and biophysical research communications

authors： Kamio K,Yoshida T,Gao C,Ishii T,Ota F,Motegi T,Kobayashi S,Fujinawa R,Ohtsubo K,Kitazume S,Angata T,Azuma A,Gemma A,Nishimura M,Betsuyaku T,Kida K,Taniguchi N

更新日期：2012-07-20 00:00:00

abstract：:Asialofetuin-tacked liposomes (AF-liposomes) encapsulating interferon (IFN)-gamma were bound and internalized into a human hepatoma cell line, HepG2 cells, selectively through asialoglycoprotein receptor, but not non-tacked liposomes (N-liposomes). AF-liposomal IFN-gamma was more effective for inhibition of viral DNA ...

journal_title：Biochemical and biophysical research communications

authors： Ishihara H,Hayashi Y,Hara T,Aramaki Y,Tsuchiya S,Koike K

更新日期：1991-01-31 00:00:00

abstract：:2H-NMR spectroscopy has been used to study the distribution of 2H atoms in brain lactate, after intraperitoneal injection of 2H2O. Information on brain metabolism was obtained from the ratio [(3-2H) lactate]/[(2-2H)-lactate] which was found very sensitive to the PO2 in the breathing air. The dependence of this ratio o...

journal_title：Biochemical and biophysical research communications

authors： Vianello F,Scarpa M,Viglino P,Rigo A

更新日期：1997-08-28 00:00:00

abstract：:A cDNA encoding non-selective type (ETB) of endothelin receptor was isolated from a human liver cDNA library. The cDNA had an open reading frame encoding a protein of 442 amino acid residues with a relative Mr of 49,643. The deduced amino acid sequence of human ETB receptor was 88% and 64% identical to those of rat lu...

journal_title：Biochemical and biophysical research communications

authors： Nakamuta M,Takayanagi R,Sakai Y,Sakamoto S,Hagiwara H,Mizuno T,Saito Y,Hirose S,Yamamoto M,Nawata H

更新日期：1991-05-31 00:00:00

abstract：:Synthetic block copolymers composed of polyoxyethylene and poly-oxypropylene have been demonstrated to possess ionophore activity selective for monovalent cations and to cause histamine release from mouse mast cells and human basophils. We now report calcium-dependent release of granule contents from human neutrophils...

journal_title：Biochemical and biophysical research communications

authors： Atkinson P,Berkow RL

更新日期：1989-08-30 00:00:00

abstract：:Hepatitis C virus (HCV), a hepacivirus member of the Flaviviridae family, has a positive-stranded RNA genome, which consists of a single open reading frame (ORF) and nontranslated regions (NTRs) at the 5' and 3' ends. The 5'NTR was found to contain an internal ribosomal entry site (IRES), which is required for the tra...

journal_title：Biochemical and biophysical research communications

authors： Kim YK,Kim CS,Lee SH,Jang SK

更新日期：2002-01-11 00:00:00

abstract：:Mycobacterium tuberculosis (TB) small heat shock protein Hsp16.3 was found to be a major membrane protein that is most predominantly expressed under oxidative stress and is localized to the thickened cell envelope. Gene knock-out studies indicate that the Hsp16.3 protein is required for TB to grow in its host macropha...

journal_title：Biochemical and biophysical research communications

authors： Abulimiti A,Qiu X,Chen J,Liu Y,Chang Z

更新日期：2003-05-23 00:00:00

abstract：BACKGROUND:Cyclosporine-A (CsA) is an immunosuppressant indicated for various immunological diseases; however, it can induce chronic kidney injury. Oxidative stress and apoptosis play a crucial role in CsA-induced nephrotoxicity. The present study evaluated the protective effect of combining 5-aminolaevulinic acid with...

journal_title：Biochemical and biophysical research communications

authors： Liu C,Zhu P,Fujino M,Isaka Y,Ito H,Takahashi K,Nakajima M,Tanaka T,Zhuang J,Li XK

更新日期：2019-01-08 00:00:00

abstract：:To identify the target autoantigens in Vogt-Koyanagi-Harada disease, we made use of an immunoscreening of a bovine uveal cDNA expression library with serum samples obtained from patients with Vogt-Koyanagi-Harada disease. We identified a novel bovine antigen and homologous human autoantigen and designated it as UACA (...

journal_title：Biochemical and biophysical research communications

authors： Yamada K,Senju S,Nakatsura T,Murata Y,Ishihara M,Nakamura S,Ohno S,Negi A,Nishimura Y

更新日期：2001-02-02 00:00:00

abstract：:Two novel neuropeptides, urechistachykinin I (H-Leu-Arg-Gln-Ser-Gln-Phe-Val-Gly-Ser-Arg-NH2) and urechistachykinin II (H-Ala-Ala-Gly-Met-Gly-Phe-Phe-Gly-Ala-Arg-NH2), were isolated from the ventral nerve cords of the echiuroid worm, Urechis unicinctus. These peptides showed a contractile action on the inner circular b...

journal_title：Biochemical and biophysical research communications

authors： Ikeda T,Minakata H,Nomoto K,Kubota I,Muneoka Y

更新日期：1993-04-15 00:00:00

abstract：:Nitrosporeusine A (NA) has been recently reported to exert anti-inflammatory and renal protective effects, but whether NA can attenuate sepsis-associated acute kidney injury (AKI) has not yet been reported. In this study, our results found that cecal ligation and puncture (CLP) reduced renal PGC-1α expression and indu...

journal_title：Biochemical and biophysical research communications

authors： Zhao Y,Nie M,Xu P,Li H,Xu L,Cheng XQ,Lei YQ

更新日期：2019-07-30 00:00:00

abstract：:By analyzing The Cancer Genome Atlas (TCGA) datasets, we discovered that the zinc finger protein 692 (ZNF692) were over-expressed in Lung adenocarcinoma (LUAD) tissues compared to adjacent non-tumor tissues (P < 0.0001). In this study, we investigated the function of ZNF692 in the progression of LUAD. We found that ZN...

journal_title：Biochemical and biophysical research communications

authors： Zhang Q,Zheng X,Sun Q,Shi R,Wang J,Zhu B,Xu L,Zhang G,Ren B

更新日期：2017-09-02 00:00:00

abstract：:The exposure of organ cultured pineal glands of Syrian hamsters to forskolin, an adenylate cyclase activator, caused marked increases in serotonin N-acetyltransferase activity and melatonin content in a dose-related manner (1-100 microM) when glands were collected in the second half of the dark period. However, additi...

journal_title：Biochemical and biophysical research communications

authors： Santana C,Guerrero JM,Reiter RJ,Gonzalez-Brito A,Menendez-Pelaez A

更新日期：1988-08-30 00:00:00

abstract：:SAP90/PSD95-associated proteins (SAPAPs) are one type of scaffold protein in the postsynaptic density (PSD). Scaffold proteins play an important role in synaptic function. Recently, many studies have shown that mutations associated with scaffold proteins cause dysfunction in neuronal circuitry and in behavior. SAPAP4,...

journal_title：Biochemical and biophysical research communications

authors： Wu B,Li C,Lei H

更新日期：2018-11-10 00:00:00

abstract：:The IGFBP7 gene encodes insulin-like growth factor protein 7. IGFPB7 is involved in diverse biological functions including cell growth regulation, senescence and apoptosis, and also acts as a tumor suppressor in multiple cancers. The IGFBP7 mRNA is subject to A-to-I RNA editing mediated by adenosine deaminases acting ...

journal_title：Biochemical and biophysical research communications

authors： Larsen K,Kristensen KK,Momeni J,Farajzadeh L,Bendixen C

更新日期：2016-10-21 00:00:00

abstract：:The effect of 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] on the growth of normal human keratinocytes cultured in serum-free medium was investigated. 1,25(OH)2D3 inhibited the cell growth at 10(-7) M by 75.3% and at 10(-6) M almost completely. The growth inhibition was accompanied by changes related to proliferation: (1) r...

journal_title：Biochemical and biophysical research communications

authors： Matsumoto K,Hashimoto K,Nishida Y,Hashiro M,Yoshikawa K

更新日期：1990-01-30 00:00:00

abstract：:Hypoxic/ischemic trauma is a primary factor in the pathology of various disease states. Yet, very little is known about the molecular mechanisms involved in cellular responses and adaptations to hypoxia. As a means of identifying intracellular signaling systems that are regulated in response to hypoxia, the effects of...

journal_title：Biochemical and biophysical research communications

authors： Beitner-Johnson D,Leibold J,Millhorn DE

更新日期：1998-01-06 00:00:00

abstract：:Recombinant human leukocyte interferon (IFN-alpha A) inhibits growth of the human promyelocytic leukemic cell line HL-60 without inducing these cells to differentiate terminally. When IFN-alpha A is combined with agents capable of inducing differentiation in HL-60 cells, such as 12-O-tetradecanoyl-phorbol-13-acetate (...

journal_title：Biochemical and biophysical research communications

authors： Grant S,Bhalla K,Weinstein B,Pestka S,Mileno MD,Fisher PB

更新日期：1985-07-16 00:00:00

abstract：:Recent studies have reported elevated expression of miR-181a in patients with non-alcoholic fatty liver disease (NAFLD), suggesting that it may play an important role in liver lipid metabolism and insulin resistance. We aimed to investigate the effect of miR-181a in lipid metabolism and find new treatments for NAFLD. ...

journal_title：Biochemical and biophysical research communications

authors： Huang R,Duan X,Liu X,Cao H,Wang Y,Fan J,Wang B

更新日期：2019-01-22 00:00:00

abstract：:Aldose reductase has been purified to homogeneity from bovine retina. It has an apparent molecular weight of 32,000 daltons and shares immunological and kinetic properties with the much studied aldose reductases purified from various sources. Retinal aldose reductase displays a K(m) of approximately 40 microM with 4-h...

journal_title：Biochemical and biophysical research communications

authors： He Q,Khanna P,Srivastava S,van Kuijk FJ,Ansari NH

更新日期：1998-06-29 00:00:00

abstract：:Specific ligands of the peripheral benzodiazepine receptor (PBR) have been shown to induce both apoptosis and G1/G0 cell cycle arrest in colorectal cancers. The signaling pathways leading to cell cycle arrest are still unknown. Using cDNA array technology, we identified signaling molecules involved in cell cycle arres...

journal_title：Biochemical and biophysical research communications

authors： Maaser K,Sutter AP,Krahn A,Höpfner M,Grabowski P,Scherübl H

更新日期：2004-11-12 00:00:00

abstract：:The renal proximal tubule (RPT) is a central locale for Na+ reabsorption, and blood pressure regulation. Na+ reabsorption in the RPT depends upon the Na,K-ATPase, which is controlled by a complex regulatory network, including Salt-Inducible Protein Kinase (SIK). SIKs are recently discovered members of the AMP-activate...

journal_title：Biochemical and biophysical research communications

authors： Taub M,Springate JE,Cutuli F

更新日期：2010-03-12 00:00:00

abstract：:Bovine myocardial sarcolemma and sarcoplasmic reticulum vesicle preparations contained calcium-dependent protease inhibitor protein. No inhibitor was detected in mitochondrial membranes. The membrane-bound inhibitor co-purified with the marker enzymes for sarcolemma and sarcoplasmic reticulum, Na+,K+-ATPase and Ca2+,K...

journal_title：Biochemical and biophysical research communications

authors： Mellgren RL,Lane RD,Kakar SS

更新日期：1987-02-13 00:00:00

abstract：:We have recently reported a novel finding that a candidate tumor suppressor gene prox1 suffered adenosine-to-inosine (A-to-I) RNA mutation without genomic mutation in a subset of human cancer cells and lost its function. Hence, screening of mutations in both cDNA and genomic DNA could be important in the analysis of c...

journal_title：Biochemical and biophysical research communications

authors： Yoshimoto T,Takahashi M,Nagayama S,Watanabe G,Shimada Y,Sakasi Y,Kubo H

更新日期：2007-07-27 00:00:00