Stereomammography: evaluation of depth perception using a virtual 3D cursor.

Abstract:

:We are evaluating the usefulness of stereomammography in improving breast cancer diagnosis. One area that we are investigating is whether the improved depth perception associated with stereomammography might be significantly enhanced with the use of a virtual 3D cursor. A study was performed to evaluate the accuracy of absolute depth measurements made in stereomammograms with such a cursor. A biopsy unit was used to produce digital stereo images of a phantom containing 50 low contrast fibrils (0.5 mm diam monofilaments) at depths ranging from 1 to 11 mm, with a minimum spacing of 2 mm. Half of the fibrils were oriented perpendicular (vertical) and half parallel (horizontal) to the stereo shift direction. The depth and orientation of each fibril were randomized, and the horizontal and vertical fibrils crossed, simulating overlapping structures in a breast image. Left and right eye images were generated by shifting the x-ray tube from +2.5 degrees to -2.5 degrees relative to the image receptor. Three observers viewed these images on a computer display with stereo glasses and adjusted the position of a cross-shaped virtual cursor to best match the perceived location of each fibril. The x, y, and z positions of the cursor were indicated on the display. The z (depth) coordinate was separately calibrated using known positions of fibrils in the phantom. The observers analyzed images of two configurations of the phantom. Thus, each observer made 50 vertical filament depth measurements and 50 horizontal filament depth measurements. These measurements were compared with the true depths. The correlation coefficients between the measured and true depths of the vertically oriented fibrils for the three observers were 0.99, 0.97, and 0.89 with standard errors of the estimates of 0.39 mm, 0.83 mm, and 1.33 mm, respectively. Corresponding values for the horizontally oriented fibrils were 0.91, 0.28, and 0.08, and 1.87 mm, 4.19 mm, and 3.13 mm. All observers could estimate the absolute depths of vertically oriented objects fairly accurately in digital stereomammograms; however, only one observer was able to accurately estimate the depths of horizontally oriented objects. This may relate to different aptitudes for stereoscopic visualization. The orientations of most objects in actual mammograms are combinations of horizontal and vertical. Further studies are planned to evaluate absolute depth measurements of fibrils oriented at various intermediate angles and of objects of different shapes. The effects of the shape and contrast of the virtual cursor and the stereo shift angle on the accuracy of the depth measurements will also be investigated.

journal_name

Med Phys

journal_title

Medical physics

authors

Goodsitt MM,Chan HP,Hadjiiski L

doi

10.1118/1.599008

subject

Has Abstract

pub_date

2000-06-01 00:00:00

pages

1305-10

issue

6

eissn

0094-2405

issn

2473-4209

journal_volume

27

pub_type

杂志文章
  • Cascade convolutional neural networks for automatic detection of thyroid nodules in ultrasound images.

    abstract:PURPOSE:It is very important for calculation of clinical indices and diagnosis to detect thyroid nodules from ultrasound images. However, this task is a challenge mainly due to heterogeneous thyroid nodules with distinct components are similar to background in ultrasound images. In this study, we employ cascade deep co...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12134

    authors: Ma J,Wu F,Jiang T,Zhu J,Kong D

    更新日期:2017-05-01 00:00:00

  • Accuracy of cranial coplanar beam therapy using an oblique, stereoscopic x-ray image guidance system.

    abstract::A system for measuring two-dimensional (2D) dose distributions in orthogonal anatomical planes in the cranium was developed and used to evaluate the accuracy of coplanar conformal therapy using ExacTrac image guidance. Dose distributions were measured in the axial, sagittal, and coronal planes using a CIRS (Computeriz...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2955751

    authors: Vinci JP,Hogstrom KR,Neck DW

    更新日期:2008-08-01 00:00:00

  • Focal spot motion of linear accelerators and its effect on portal image analysis.

    abstract::The focal spot of a linear accelerator is often considered to have a fully stable position. In practice, however, the beam control loop of a linear accelerator needs to stabilize after the beam is turned on. As a result, some motion of the focal spot might occur during the start-up phase of irradiation. When acquiring...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1576229

    authors: Sonke JJ,Brand B,van Herk M

    更新日期:2003-06-01 00:00:00

  • Model-based calculations of off-axis ratio of conic beams for a dedicated 6 MV radiosurgery unit.

    abstract:PURPOSE:Because the small-radius photon beams shaped by cones in stereotactic radiosurgery (SRS) lack lateral electronic equilibrium and a detector's finite cross section, direct experimental measurement of dosimetric data for these beams can be subject to large uncertainties. As the dose calculation accuracy of a trea...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3488900

    authors: Yang JN,Ding X,Du W,Pino R

    更新日期:2010-10-01 00:00:00

  • Oxygen distribution in tumors: a qualitative analysis and modeling study providing a novel Monte Carlo approach.

    abstract:PURPOSE:To construct a Monte Carlo (MC)-based simulation model for analyzing the dependence of tumor oxygen distribution on different variables related to tumor vasculature [blood velocity, vessel-to-vessel proximity (vessel proximity), and inflowing oxygen partial pressure (pO2)]. METHODS:A voxel-based tissue model c...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4892386

    authors: Lagerlöf JH,Kindblom J,Bernhardt P

    更新日期:2014-09-01 00:00:00

  • Active energy selective image detector for dual-energy computed radiography.

    abstract::A new energy selective detector for dual energy computed radiography has been developed that combines many of the advantages of x-ray tube voltage switching and single exposure double screen detectors. The new active detector utilizes electro-optical modulation of the response of the storage phosphor screens to allow ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597831

    authors: Alvarez RE

    更新日期:1996-10-01 00:00:00

  • Electron dosimetry based on the absorbed dose to water concept: a comparison of the AAPM TG-51 and DIN 6800-2 protocols.

    abstract::The dosimetry protocols DIN 6800-2 and AAPM TG-51, both based on the absorbed dose to water concept, are compared in their theoretical background and in their application to electron dosimetry. The agreement and disagreement in correction factors and energy parameters used in both protocols will be shown and discussed...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1414008

    authors: Dohm OS,Christ G,Nüsslin F,Schüle E,Bruggmoser G

    更新日期:2001-11-01 00:00:00

  • Real-time direct diaphragm tracking using kV imaging on a standard linear accelerator.

    abstract:PURPOSE:As the predominant driver of respiratory motion, the diaphragm represents a key surrogate for motion management during the irradiation of thoracic cancers. Existing approaches to diaphragm tracking often produce phase-based estimates, suffer from lateral side failures or are not executable in real-time. In this...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13738

    authors: Hindley N,Keall P,Booth J,Shieh CC

    更新日期:2019-10-01 00:00:00

  • Large field of view distortion assessment in a low-field MR-linac.

    abstract:PURPOSE:MR-guided radiation therapy (RT) offers unparalleled soft tissue contrast for localization and target tracking. However, MRI distortions may be detrimental to high precision RT. This work characterizes the gradient nonlinearity (GNL) and total distortions over the first year of clinical operation of a 0.35T MR-...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13467

    authors: Nejad-Davarani SP,Kim JP,Du D,Glide-Hurst C

    更新日期:2019-05-01 00:00:00

  • Sci-Fri PM: Planning-03: Fundamental understanding of the inter-relation of arc range, angular dose rate and MLC leaf position optimization of Intensity Modulated Arc Therapy for a concave target.

    abstract::Intensity Modulated Arc Therapy (IMAT) is a rotational variant of Intensity Modulated Radiation Therapy (IMRT) that can be implemented with or without angular dose rate optimization. The purpose of this study is to determine the inter-relationship among arc range, Multi-Leaf Collimator (MLC) leaf positions and angular...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2965975

    authors: Oliver M,Chen J,Wong E

    更新日期:2008-07-01 00:00:00

  • The NMR blood flowmeter--applications.

    abstract::Nuclear Magnetic Resonance (NMR) permits the noninvasive measurement of blood flow signals unimpaired by clothes, bandages, casts, etc. The cylindrical crossed-coil NMR blood flowmeter was used to measure blood flow through a cross-section of the human forearm. Two calibration procedures are described: one for pulsati...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594989

    authors: Salles-Cunha SX,Halbach RE,Battocletti JH,Sances A Jr

    更新日期:1981-07-01 00:00:00

  • A systematic Monte Carlo study of secondary electron fluence perturbation in clinical proton beams (70-250 MeV) for cylindrical and spherical ion chambers.

    abstract::Current dosimetry protocols for clinical protons do not take into account any secondary electron fluence perturbation in ion chambers. In this work, we performed a systematic study of secondary electron fluence perturbation factors for spherical and cylindrical ion chambers in proton beams (70-250 MeV). The electron f...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1406519

    authors: Verhaegen F,Palmans H

    更新日期:2001-10-01 00:00:00

  • Depth dose characteristics of 24-MV x-ray beams at extended SSD.

    abstract::Depth dose characteristics of 24-MV beams from a medical linear accelerator at various SSDs have been measured. The dose buildup, percent depth dose (PDD), and output were measured using ionization chambers and a diode detector under full scatter. Surface dose ranged from 8% to 51% depending upon the collimator settin...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596673

    authors: Jani SK,Pennington EC

    更新日期:1991-03-01 00:00:00

  • Tissue equivalence in clinical neutron dosimetry: comparison of dose distributions in nine tissue substitutes for a d(14)Be neutron beam.

    abstract::Depth dose distributions for a d(14)Be neutron beam, measured separately for total and gamma absorbed dose, are presented for nine tissue substitutes and for two field sizes. These data are used to examine methods to transform depth dose curves from one material to another. Best results are found when the local depths...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595695

    authors: Hensley FW,Rassow J,Temme A

    更新日期:1985-05-01 00:00:00

  • Semiautomated four-dimensional computed tomography segmentation using deformable models.

    abstract::The purpose of this work is to demonstrate a proof of feasibility of the application of a commercial prototype deformable model algorithm to the problem of delineation of anatomic structures on four-dimensional (4D) computed tomography (CT) image data sets. We acquired a 4D CT image data set of a patient's thorax that...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1929207

    authors: Ragan D,Starkschall G,McNutt T,Kaus M,Guerrero T,Stevens CW

    更新日期:2005-07-01 00:00:00

  • Practical cone-beam lambda tomography.

    abstract::As a potentially important technology for medical x-ray computed tomography (CT), lambda tomography (LT) is to reconstruct a gradient-like image only from local projection data. Based on our recently derived exact fan-beam LT formula, [H. Y. Gu and G. Wang, Int. J. Biomed. Imaging 2006(1), 1-9 (2006)] here we propose ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2348767

    authors: Yu H,Ye Y,Wang G

    更新日期:2006-10-01 00:00:00

  • Attenuation, scattering, and absorption of ultrasound in the skull bone.

    abstract:PURPOSE:Measured values of ultrasound attenuation in bone represent a combination of different loss mechanisms. As a wave is transmitted from a fluid into bone, reflections occur at the interface. In the bone, mode conversion occurs between longitudinal and shear modes and the mechanical wave is scattered by its comple...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3668316

    authors: Pinton G,Aubry JF,Bossy E,Muller M,Pernot M,Tanter M

    更新日期:2012-01-01 00:00:00

  • High-resolution fiber-optic dosimeters for microbeam radiation therapy.

    abstract:PURPOSE:A high resolution, water equivalent, optical and passive x-ray dosimeter has been constructed using plastic scintillator and optical fiber. This dosimeter has a peak edge-on spatial resolution of 100 μm in one dimension, with a 10 μm resolution dosimeter under investigation. The dosimeter design has a potential...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12209

    authors: Archer J,Li E,Petasecca M,Lerch M,Rosenfeld A,Carolan M

    更新日期:2017-05-01 00:00:00

  • Image-based 3D modeling study of the influence of vessel density and blood hemoglobin concentration on tumor oxygenation and response to irradiation.

    abstract:PURPOSE:Hypoxia is one of the most important factors influencing clinical outcome after radiotherapy. Improved knowledge of factors affecting the levels and distribution of oxygen within a tumor is needed. The authors constructed a theoretical 3D model based on histological images to analyze the influence of vessel den...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4773886

    authors: Lagerlöf JH,Kindblom J,Cortez E,Pietras K,Bernhardt P

    更新日期:2013-02-01 00:00:00

  • SU-E-T-118: Characterization of EBT3 Films in Photon and Proton Beams.

    abstract:PURPOSE:To measure the calibration curves of EBT3 dosimetry films in photon and proton beams and to quantify the related uncertainties from one beam type to another. METHODS:EBT3 Gafchromic films have similar properties than EBT2 with a symmetric construction and a matte polyester substrate to prevent Newton's ring ar...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735176

    authors: Sorriaux J,Rossomme S,Kacperek A,Bertrand D,Vynckier S,Sterpin E

    更新日期:2012-06-01 00:00:00

  • Monte Carlo dosimetry for 103Pd, 125I, and 131Cs ocular brachytherapy with various plaque models using an eye phantom.

    abstract:PURPOSE:To investigate dosimetry for ocular brachytherapy for a range of eye plaque models containing(103)Pd, (125)I, or (131)Cs seeds with model-based dose calculations. METHODS:Five representative plaque models are developed based on a literature review and are compared to the standardized COMS plaque, including pla...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4864474

    authors: Lesperance M,Martinov M,Thomson RM

    更新日期:2014-03-01 00:00:00

  • Investigation of three radiation detectors for accurate measurement of absorbed dose in nonstandard fields.

    abstract:PURPOSE:To establish accurate experimental dosimetry techniques for reference dose measurements in nonstandard composite fields. METHODS:A cylindrical PMMA phantom filled with water was constructed, at the center of which reference absorbed dose to water for a head and neck IMRT delivery was measured. Based on the pro...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3392247

    authors: Chung E,Bouchard H,Seuntjens J

    更新日期:2010-06-01 00:00:00

  • An improved electron energy-loss straggling algorithm for Monte Carlo transport codes.

    abstract::The commonly used Blunck and Leisegang electron energy-loss distribution falls off too rapidly with increasing energy loss. Also, for large thicknesses and/or low-Z media, where their distribution should approach Landau's, it normalizes to 0.92 rather than 1.0, it overestimates the number of very small energy-loss eve...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595500

    authors: Weinhous MS,Nath R

    更新日期:1984-05-01 00:00:00

  • SU-E-J-160: 4D Dynamic Arc of Non-Modulated Variable-Dose-Rate Fields for Lung SBRT: A Feasibility Study.

    abstract:PURPOSE:Conformal SBRT plans for Lung cancer with static gantry angles are ideal candidates for applying motion tracking because of: (1) better dosimetric conformity with reduced target margin and (2) easier and more faithful target tracking without intensity modulation. This work is to demonstrate that by delivering t...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4734998

    authors: Yi B,Yang X,Niu Y,Yu C

    更新日期:2012-06-01 00:00:00

  • Relaxing leaf-motion restrictions in dynamic multileaf collimator leaf sequencing.

    abstract:PURPOSE:Traditionally, unidirectional leaf-sweeping schemes have been employed to deliver IMRT plans using the dynamic multileaf collimator (DMLC) technique. The goal of this research is to investigate the potential impact of relaxing the leaf-motion restrictions in DMLC IMRT on the beam-modulation quality and the deli...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13158

    authors: Mirzapour SA,Salari E

    更新日期:2018-11-01 00:00:00

  • Transient noise characterization and filtration in CCD cameras exposed to stray radiation from a medical linear accelerator.

    abstract::Charge coupled devices (CCDs) are being increasingly used in radiation therapy for dosimetric purposes. However, CCDs are sensitive to stray radiation. This effect induces transient noise. Radiation-induced noise strongly alters the image and therefore limits its quantitative analysis. The purpose of this work is to c...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2975147

    authors: Archambault L,Briere TM,Beddar S

    更新日期:2008-10-01 00:00:00

  • A novel approach in electron beam radiation therapy of lips carcinoma: a Monte Carlo study.

    abstract:PURPOSE:Squamous cell carcinoma (SCC) is commonly treated by electron beam radiotherapy (EBRT) followed by a boost via brachytherapy. Considering the limitations associated with brachytherapy, in this study, a novel boosting technique in EBRT of lip carcinoma using an internal shield as an internal dose enhancer tool (...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4795756

    authors: Shokrani P,Baradaran-Ghahfarokhi M,Zadeh MK

    更新日期:2013-04-01 00:00:00

  • A clinically feasible method for the detection of potential collision in proton therapy.

    abstract:PURPOSE:Potential collision between the patient∕couch and the gantry could delay the start of the treatment and reduce clinical efficiency. The ability to accurately detect possible collisions during the treatment planning phase is desired. Such collision detection should account for the specific proton gantry design, ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4760988

    authors: Zou W,Lin H,Plastaras JP,Wang H,Bui V,Vapiwala N,McDonough J,Tochner Z,Both S

    更新日期:2012-11-01 00:00:00

  • Experimental test of theoretical models for time-resolved reflectance.

    abstract::Four different expressions, derived from the diffusion theory or the random walk model, were used to fit time-resolved reflectance data for the evaluation of tissue optical properties. The experimental reflectance curves were obtained from phantoms of known optical parameters (absorption and transport scattering coeff...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597739

    authors: Cubeddu R,Pifferi A,Taroni P,Torricelli A,Valentini G

    更新日期:1996-09-01 00:00:00

  • Design of a focused collimator for proton therapy spot scanning using Monte Carlo methods.

    abstract:PURPOSE:When designing a collimation system for pencil beam spot scanning proton therapy, a decision must be made whether or not to rotate, or focus, the collimator to match beamlet deflection as a function of off-axis distance. If the collimator is not focused, the beamlet shape and fluence will vary as a function of ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14139

    authors: Geoghegan TJ,Nelson NP,Flynn RT,Hill PM,Rana S,Hyer DE

    更新日期:2020-07-01 00:00:00