Experimental test of theoretical models for time-resolved reflectance.

Abstract:

:Four different expressions, derived from the diffusion theory or the random walk model, were used to fit time-resolved reflectance data for the evaluation of tissue optical properties. The experimental reflectance curves were obtained from phantoms of known optical parameters (absorption and transport scattering coefficients) covering the range of typical values for biological tissues between 600 and 900 nm. The measurements were performed using an instrumentation for time-correlated single-photon counting. The potential of the four methods in the assessment of the absorption and transport scattering coefficients was evaluated in terms of absolute error, linearity error, and dispersion of data. Each method showed different performances depending on the optical properties of the sample and the experimental conditions. We propose some criteria for the optimal choice of the fitting method to be used in different applications.

journal_name

Med Phys

journal_title

Medical physics

authors

Cubeddu R,Pifferi A,Taroni P,Torricelli A,Valentini G

doi

10.1118/1.597739

subject

Has Abstract

pub_date

1996-09-01 00:00:00

pages

1625-33

issue

9

eissn

0094-2405

issn

2473-4209

journal_volume

23

pub_type

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