Expression of intrapulmonary surfactant apoprotein-A in autopsied lungs: comparative study of cases with or without pulmonary hypoplasia.

abstract：:The ciliated, mucus-secreting urn cell complex (UCC) is found swimming in the coelomic cavity of the marine invertebrate Sipunculus nudus. This cell complex, which can be maintained in suspension cultures, responds to various stimuli by hypersecreting mucus in the form of a cohesive mucus "tail." This tail can be meas...

journal_title：Pediatric research

authors： Kurlandsky LE,Berninger RW,Talamo RC

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:We examined the extent of fetal lung hypoplasia and lung maturation using the amniotic lamellar body count (LBC) in congenital diaphragmatic hernia (CDH). METHODS:We obtained 30 amniotic fluid samples from human CDH cases during cesarean section. We assessed LBC, magnetic resonance imaging (MRI), and ultras...

journal_title：Pediatric research

authors： Watanabe Y,Tsuda H,Kotani T,Sumigama S,Mano Y,Hayakawa M,Sato Y,Kikkawa F

更新日期：2013-03-01 00:00:00

abstract：:We studied the effect of maternal concentration and mode of administration on transfer rate of TSH-releasing hormone (TRH) in an in vitro model of dually perfused isolated lobule of human term placenta. Varying concentrations (4-40 microg dL(-1)) of TRH were added either to the open maternal circulation to mimic an in...

journal_title：Pediatric research

authors： Bajoria R,Fisk NM

更新日期：1997-05-01 00:00:00

abstract：:The effect of ingestion of uncooked cornstarch (2 g/kg body weight) in water, uncooked starch (1 g/kg) added to a meal, and glucose (2 g/kg) in water, was studied in eight patients with type IA glycogen storage disease (GSD) and one patient with type IB GSD. Blood glucose concentrations were determined at 30-min inter...

journal_title：Pediatric research

authors： Smit GP,Berger R,Potasnick R,Moses SW,Fernandes J

更新日期：1984-09-01 00:00:00

abstract：:The possible role played by albumin in regulating brain metabolism during development has been studied. The effects of fatty acid-free BSA on lactate, glucose, 3-hydroxybutyrate, and glutamine oxidation and lipogenesis by rat neurons and astrocytes from primary culture were studied. The rate of lactate oxidation and l...

journal_title：Pediatric research

authors： Vicario C,Tabernero A,Medina JM

更新日期：1993-12-01 00:00:00

abstract：:The lipid profile, total cholesterol, triglycerides, and lipoproteins (beta-, pre-beta-, and alpha-) of cord blood, is presented for 419 black and white infants (94% of the eligible population) born during an 18-month period in Bogalusa, Louisiana. At birth, white neonates of both sexes had higher average levels than ...

journal_title：Pediatric research

authors： Frerichs RR,Srinivasan SR,Webber LS,Rieth MC,Berenson GS

更新日期：1978-08-01 00:00:00

abstract：:Mutations in multidrug resistance 3 gene (MDR3 or ABCB4) underlie progressive familial intrahepatic cholestasis type 3 (PFIC3), a severe pediatric liver disease progressing to cirrhosis. Abcb4-/- mice exhibit slowly developing hepatic lesions that can be accelerated by feeding a cholic acid (CA)-supplemented diet. We ...

journal_title：Pediatric research

authors： Lamireau T,Bouchard G,Yousef IM,Clouzeau-Girard H,Rosenbaum J,Desmoulière A,Tuchweber B

更新日期：2007-02-01 00:00:00

abstract：:Treatment with phototherapy or with the lipase inhibitor orlistat decreases plasma unconjugated bilirubin (UCB) concentrations in hyperbilirubinemic Gunn rats. We investigated the mechanism(s) underlying the effects of orlistat, phototherapy, and combined treatment, using steady-state 3H-UCB kinetics. After three week...

journal_title：Pediatric research

authors： Hafkamp AM,Havinga R,Ostrow JD,Tiribelli C,Pascolo L,Sinaasappel M,Verkade HJ

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Some of the health advantages of breast-fed as compared to formula-fed infants have been suggested to be due to metabolic programming effects resulting from early nutrition. METHODS:In a prospective double-blinded randomized trial, 160 infants <2 mo of age were randomized to experimental formula (EF) with a...

journal_title：Pediatric research

authors： Timby N,Lönnerdal B,Hernell O,Domellöf M

更新日期：2014-10-01 00:00:00

abstract：:In seven patients with mucopolysaccharidoses (1 Hurler, 1 Hurler-Scheie, 4 Hunter, 1 Sly), cranial (1)H-magnetic resonance spectroscopy was performed to evaluate the accumulation of mucopolysaccharides and biochemical changes in the CNS in vivo before and after bone marrow transplantation (BMT). In two of seven patien...

journal_title：Pediatric research

authors： Takahashi Y,Sukegawa K,Aoki M,Ito A,Suzuki K,Sakaguchi H,Watanabe M,Isogai K,Mizuno S,Hoshi H,Kuwata K,Tomatsu S,Kato S,Ito T,Kondo N,Orii T

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Current tools to predict the severity of respiratory syncytial virus (RSV) infection might be improved by including immunological parameters. We hypothesized that a combination of inflammatory markers would differentiate between severe and mild disease in RSV-infected children. METHODS:Blood and nasopharyng...

journal_title：Pediatric research

authors： Brand HK,Ferwerda G,Preijers F,de Groot R,Neeleman C,Staal FJ,Warris A,Hermans PW

更新日期：2013-02-01 00:00:00

abstract：:The influence of maternal stress during pregnancy on the postpartum iron status and immune maturation of infants was investigated in a nonhuman primate model. Forty infant rhesus monkeys were generated from two types of disturbed pregnancies, early or late gestation stress, and compared with 24 undisturbed controls. P...

journal_title：Pediatric research

authors： Coe CL,Lubach GR,Shirtcliff EA

更新日期：2007-05-01 00:00:00

abstract：:Prenatal maternal stress has been shown to impair functioning in nonhuman primate offspring. Little is known about the effects of prenatal stress on intellectual and language development in humans because it is difficult to identify sufficiently large samples of pregnant women who have been exposed to an independent s...

journal_title：Pediatric research

authors： Laplante DP,Barr RG,Brunet A,Galbaud du Fort G,Meaney ML,Saucier JF,Zelazo PR,King S

更新日期：2004-09-01 00:00:00

abstract：:A 2-month-old white girl had severe liver disease (but without signs of hepatic necrosis, infection or cirrhosis), urinary cytomegalovirus, transient reduction of alpha 1-antitrypsin concentration and transient abnormal alpha 1-antitrypsin phenotype that were not present in her parents. Five serum specimens that were ...

journal_title：Pediatric research

authors： Hug G,Chuck G,Bowles B

更新日期：1982-03-01 00:00:00

abstract：:The placenta is essential to nutrition before birth. Recent work has shown that a range of clearly defined alterations can be found in the placentas of infants with intrauterine growth restriction (IUGR). In the mouse, a placental specific knockout of a single imprinted gene, encoding IGF-2, results in one pattern of ...

journal_title：Pediatric research

authors： Sibley CP,Turner MA,Cetin I,Ayuk P,Boyd CA,D'Souza SW,Glazier JD,Greenwood SL,Jansson T,Powell T

更新日期：2005-11-01 00:00:00

abstract：:A recently introduced test measures the concentration of transferrin receptor (TfR) in serum, which increases shortly after the onset of iron deficiency. In adults this increase reflects the degree to which tissue iron availability is impaired. We developed a fluoroimmunoassay to quantify TfR. The purpose of this stud...

journal_title：Pediatric research

authors： Kivivuori SM,Anttila R,Viinikka L,Pesonen K,Siimes MA

更新日期：1993-09-01 00:00:00

abstract：:Long-term EEG monitoring (LTM) with several electrodes could be a useful tool for surveillance of the brain during the first critical days of life. This study aimed to assess the feasibility of multichannel LTM for automated analysis of EEG activity from d 1 to 3 using eight electrodes. Premature infants (GA <31 wk; n...

journal_title：Pediatric research

authors： Schumacher EM,Westvik AS,Larsson PG,Lindemann R,Westvik J,Stiris TA

更新日期：2011-05-01 00:00:00

abstract：:Amplitude-integrated EEG (aEEG) is used to select patients for neuroprotective therapy after perinatal asphyxia because of its prognostic accuracy within several hours after birth. We aimed to determine the natural course of aEEG patterns during the first 72 h of life, in relation to neurologic outcome, in a group of ...

journal_title：Pediatric research

authors： ter Horst HJ,Sommer C,Bergman KA,Fock JM,van Weerden TW,Bos AF

更新日期：2004-06-01 00:00:00

abstract：:We describe a method based on a Fabry-Perot interferometer at the tip of an optic fiber with a diameter of 0.25 mm for direct measurement of tracheal pressure in pediatric respiratory monitoring. The response time of the pressure transducer and its influence on the resistance of pediatric endotracheal tubes (internal ...

journal_title：Pediatric research

authors： Sondergaard S,Karason S,Hanson A,Nilsson K,Hojer S,Lundin S,Stenqvist O

更新日期：2002-03-01 00:00:00

abstract：:Although tyrosine is considered indispensable during the neonatal period, its poor solubility has limited its inclusion in parenteral amino acid solutions to less than 1% of total amino acids. Dipeptides of tyrosine are highly soluble, have been shown to be well used and safe in animal models and humans, and, therefor...

journal_title：Pediatric research

authors： Roberts SA,Ball RO,Moore AM,Filler RM,Pencharz PB

更新日期：2001-01-01 00:00:00

abstract：:This study examined the relationships between cerebral fractional oxygen extraction (FOE), mean arterial blood pressure (MABP), left ventricular output (LVO), blood gases, and other physiologic variables in 36 very-low-birth-weight preterm infants during the first 3 d after birth. There was a decrease in cerebral FOE ...

journal_title：Pediatric research

authors： Kissack CM,Garr R,Wardle SP,Weindling AM

更新日期：2004-03-01 00:00:00

abstract：:In order to study the neonatal microcirculation, the capillary hemodynamics in skin was investigated in 43 full-term infants 2-7 days after birth. The nailfold capillaries of the thumb were visualized by means of television microscopy and the capillary blood cell velocity (CBV) was videophotometrically quantified in 1...

journal_title：Pediatric research

authors： Norman M,Herin P,Fagrell B,Zetterström R

更新日期：1988-06-01 00:00:00

abstract：:To determine the pathophysiologic significance of pertussis toxin (PT) on the human beta-adrenergic system, beta-adrenoceptor (beta-R)-density and cyclic AMP response of peripheral mononuclear blood cells (MN leukocytes) were studied in children during the paroxysmal stage of natural pertussis infection, after vaccina...

journal_title：Pediatric research

authors： Griese M,Sideropoulou O,Reinhardt D

更新日期：1989-02-01 00:00:00

abstract：:Sudden infant death syndrome (SIDS) is multifactorial and may result from the interaction of a number of environmental, genetic, and developmental factors. We studied three major genes causing long QT syndrome in 42 Japanese SIDS victims and found five mutations, KCNQ1-K598R, KCNH2-T895M, SCN5A-F532C, SCN5A-G1084S, an...

journal_title：Pediatric research

authors： Otagiri T,Kijima K,Osawa M,Ishii K,Makita N,Matoba R,Umetsu K,Hayasaka K

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Secreted frizzled-related protein 5 (SFRP5) is an adipokine protecting against obesity-related insulin resistance and diabetes. SFRP5 binds to wingless type mouse mammary tumor virus (MMTV) integration site family member 5A (WNT5A) to improve insulin sensitivity. We performed the first study of SFRP5 and WNT...

journal_title：Pediatric research

authors： Prats-Puig A,Soriano-Rodríguez P,Carreras-Badosa G,Riera-Pérez E,Ros-Miquel M,Gomila-Borja A,de Zegher F,Ibáñez L,Bassols J,López-Bermejo A

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The epithelial-mesenchymal transition (EMT) has been implicated as a key mechanism in the pathogenesis of liver fibrosis. The miR-200 family has been shown to inhibit EMT. METHODS:Liver fibrosis levels were assessed with Masson's trichrome staining of liver samples obtained from biliary atresia (BA) patient...

journal_title：Pediatric research

authors： Xiao Y,Zhou Y,Chen Y,Zhou K,Wen J,Wang Y,Wang J,Cai W

更新日期：2015-02-01 00:00:00

abstract：:Prothrombin of newborns was investigated by means of the quantitative immunoelectrophoresis and the two-dimensional immunoelectrophoresis. The plasma of 10 of 24 healthy term newborns and of 5 preterm infants taken immediately after birth showed one prothrombin precipitate in the alpha-2-beta-globulin position when a ...

journal_title：Pediatric research

authors： Muntean W,Petek W,Rosanelli K,Mutz ID

更新日期：1979-11-01 00:00:00

abstract：:Plasma, amniotic fluid, and tissue concentrations of IGF-I were examined in nutritionally deprived, growth-retarded fetal rats to determine whether IGF-I concentration serves as a marker for nutritional status. Growth retardation was induced by 72 h of maternal fasting. Twenty-three control and 17 growth-retarded fetu...

journal_title：Pediatric research

authors： Bernstein IM,DeSouza MM,Copeland KC

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Therapeutic hypothermia (TH) has become standard treatment for severe and moderate hypoxic-ischemic neonatal encephalopathy (HIE). Our group has developed an optically based, noninvasive concept of assessing the capacity for oxygen delivery from the microcirculation to the cells of a tissue under investigati...

journal_title：Pediatric research

authors： Fredly S,Fugelseth D,Nygaard CS,Salerud EG,Stiris T,Kvernebo K

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:To determine associations of low superior vena cava (SVC) flow (≤55 ml/kg/min) and low right ventricular output (RVO) (≤150 ml/kg/min) in preterm infants. DESIGN/METHODS:An observational study in infants <30 weeks gestation randomized to receive immediate (<10 s) or delayed cord clamping (DCC) (≥60 s). RESU...

journal_title：Pediatric research

authors： Popat H,Robledo KP,Kirby A,Sebastian L,Evans N,Gill A,Kluckow M,Sinhal S,de Waal K,Tarnow-Mordi W,Osborn D

更新日期：2019-07-01 00:00:00