Cerebral fractional oxygen extraction in very low birth weight infants is high when there is low left ventricular output and hypocarbia but is unaffected by hypotension.

abstract：:We assessed the patterns of Helicobacter pylori (H. pylori) specific maternal antibodies in maternal serum, cord blood, and milk, which might play a role in prevention of H. pylori infection because transferred to the infant. Between November 2000 and November 2001, mothers were recruited after delivery of their offsp...

journal_title：Pediatric research

authors： Weyermann M,Borowski C,Bode G,Gürbüz B,Adler G,Brenner H,Rothenbacher D

更新日期：2005-11-01 00:00:00

abstract：:Our goal was to determine the relationship between 4 amniotic fluid (AF) proteomic biomarkers (human neutrophil defensins 2 and 1, calgranulins C and A) characteristic of intra-amniotic inflammation, and funisitis and early-onset sepsis in premature neonates. The mass restricted (MR) score was generated from AF obtain...

journal_title：Pediatric research

authors： Buhimschi CS,Buhimschi IA,Abdel-Razeq S,Rosenberg VA,Thung SF,Zhao G,Wang E,Bhandari V

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:We examined the extent of fetal lung hypoplasia and lung maturation using the amniotic lamellar body count (LBC) in congenital diaphragmatic hernia (CDH). METHODS:We obtained 30 amniotic fluid samples from human CDH cases during cesarean section. We assessed LBC, magnetic resonance imaging (MRI), and ultras...

journal_title：Pediatric research

authors： Watanabe Y,Tsuda H,Kotani T,Sumigama S,Mano Y,Hayakawa M,Sato Y,Kikkawa F

更新日期：2013-03-01 00:00:00

abstract：:Normal values for the percentages of lymphocytes carrying surface membrane-bound immunoglobulin, or rosetting with sheep erythrocytes, ox erythrocytes coated with rabbit immunoglobulin G, or ox erythrocytes coated with rabbit immunoglobulin M and reacted with human serum partially de-complemented with zymozan, have be...

journal_title：Pediatric research

authors： Stern CM

更新日期：1979-06-01 00:00:00

abstract：:We investigated the role of circulating bone marrow cells (BMC) in cardiomyocyte regeneration. BMC, isolated from transgenic mice expressing enhanced green fluorescent protein (GFP), were transplanted into lethally irradiated C57BL6 mice. Five weeks after bone marrow transplantation (BMT), flow cytometric analysis for...

journal_title：Pediatric research

authors： Kuramochi Y,Fukazawa R,Migita M,Hayakawa J,Hayashida M,Uchikoba Y,Fukumi D,Shimada T,Ogawa S

更新日期：2003-09-01 00:00:00

abstract：:The classical model of gene regulation by hormones involves a hormone-bound receptor interacting with a DNA response element to increase or decrease gene transcription. Steroid hormone regulation more commonly involves atypical cis-elements, co-receptors, accessory proteins, and unique modes of interaction on differen...

journal_title：Pediatric research

authors： McNab TC,Tseng YT,Stabila JP,McGonnigal BG,Padbury JF

更新日期：2001-11-01 00:00:00

abstract：INTRODUCTION:The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) serves 50% of infants and 25% of preschool-aged children in the United States and collects height and weight measurements from eligible children every 6 mo, making WIC data a valuable resource for studying childhood growth an...

journal_title：Pediatric research

authors： Crespi CM,Alfonso VH,Whaley SE,Wang MC

更新日期：2012-03-01 00:00:00

abstract：:Carlo Agostoni, MD, and Kwang Sik Kim, MD, are the Guest Editors for this annual review issue on Nutrition and the Microbiome. Dr Agostoni is a Professor of Pediatrics at the Department of Clinical Sciences and Community Health, University of Milan, within the Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, ...

journal_title：Pediatric research

authors： Agostoni C,Kim KS

更新日期：2015-01-01 00:00:00

abstract：:The effects of passive respiratory syncytial virus (RSV) immune serum given as preinoculation prophylaxis, postinoculation prophylaxis, and as therapy on d 5 after inoculation were evaluated in an illness model of RSV infection in BALB/c mice. Pre- and postinoculation prophylaxis reduced RSV replication in lung after ...

journal_title：Pediatric research

authors： Graham BS,Davis TH,Tang YW,Gruber WC

更新日期：1993-08-01 00:00:00

abstract：:To localize fetal rabbit lung beta-adrenoreceptors before and after glucocorticoid treatment, light microscopic autoradiography was performed with the reversible radiolabeled beta-adrenergic antagonist, [3H]dihydroalprenolol, on day 26 of gestation. Autoradiograms of adult lung and fetal myocardium were also prepared....

journal_title：Pediatric research

authors： Barnes P,Jacobs M,Roberts JM

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Aminoglycoside exposure is a common cause of acute kidney injury (AKI). Delay in the diagnosis of AKI using conventional biomarkers has been one of the important obstacles in applying early effective interventions. We tested the hypothesis that urinary metabolomics could identify novel early biomarkers for t...

journal_title：Pediatric research

authors： Hanna MH,Segar JL,Teesch LM,Kasper DC,Schaefer FS,Brophy PD

更新日期：2013-05-01 00:00:00

abstract：:Circadian rhythms of plasma renin activity (PRA) and plasma aldosterone (PA) were studied in eight healthy children, 7 to 15 years old. Blood samples were obtained at 7:00 AM, 10:00 AM, 1:00 PM, 4:00 PM, 5:00 PM, 8.00 PM, and midnight on day 1 and 4:00 AM and 7:00 AM on day 2. Children had normal activity during this ...

journal_title：Pediatric research

authors： Dechaux M,Broyer M,Lenoir G,Limal JM,Sachs C

更新日期：1982-05-01 00:00:00

abstract：:Recombinant human erythropoietin (rEpo) is neuroprotective in neonatal models of hypoxic-ischemic brain injury. However, the optimal rEpo dose, dosing interval, and number of doses for reducing brain injury are still undetermined. We compared the neuroprotective efficacy of several subcutaneous rEpo treatment regimens...

journal_title：Pediatric research

authors： Kellert BA,McPherson RJ,Juul SE

更新日期：2007-04-01 00:00:00

abstract：:Infantile Refsum's disease is characterized by high levels of phytanic acid and the absence of normal hepatic peroxisomes. We investigated the in vivo influence of phytol, a precursor of phytanic acid, on peroxisomes by both biochemical and morphological methods. Enhanced supply of phytol in the diet of adult mice cau...

journal_title：Pediatric research

authors： Van den Branden C,Vamecq J,Wybo I,Roels F

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:A lack of consensus exists as to the timing of kidney biopsy in children with steroid-dependent nephrotic syndrome (SDNS) where minimal change disease (MCD) predominates. This study aimed at examining the applicability of a biomarker-assisted risk score model to select SDNS patients at high risk of focal seg...

journal_title：Pediatric research

authors： Chan CY,Resontoc LP,Qader MA,Chan YH,Liu ID,Lau PY,Than M,Yeo WS,Loh AH,Tan PH,Wei C,Reiser J,Biswas SK,Ng KH,Yap HK

更新日期：2019-03-01 00:00:00

abstract：:Cerebral magnetic resonance imaging (MRI) has revealed white matter changes in patients with phenylketonuria (PKU), an inborn error of metabolism with increased plasma phenylalanine level. Because the significance of these lesions is unknown, this study was undertaken to determine whether glucose metabolism was depres...

journal_title：Pediatric research

authors： Hasselbalch S,Knudsen GM,Toft PB,Høgh P,Tedeschi E,Holm S,Videbaek C,Henriksen O,Lou HC,Paulson OB

更新日期：1996-07-01 00:00:00

abstract：:To study the effects of podocyte injury on glomerular maturation and underlying mechanisms of such effects, puromycin aminonucleoside (PAN) was given to neonatal mice at 1 d post partum (1 dpp). Mice with PAN injection had smaller kidney weight (KW) and body weight (BW) at all times and smaller KW/BW at 4, 8, and 12 d...

journal_title：Pediatric research

authors： Ma J,Rossini M,Yang HC,Zuo Y,Fogo AB,Ichikawa I

更新日期：2007-10-01 00:00:00

abstract：:Based on the serum phenylalanine levels under free diet patients with hyperphenylalaninemia are classified as "classical" (>1200 micromol/L), "mild" (600-1200 micromol/L), or "non-phenylketonuria (PKU)-hyperphenylalaninemia" (<600 micromol/L). Recent studies revealed intellectual, neurologic, and neuropsychologic defi...

journal_title：Pediatric research

authors： Weglage J,Ullrich K,Pietsch M,Fünders B,Güttler F,Harms E

更新日期：1997-09-01 00:00:00

abstract：:We have previously discovered that the adult Drosophila melanogaster is tolerant to a low O2 environment, withstanding hours of total O2 deprivation without showing any evidence of cell injury. Subsequently, our laboratory embarked on the study of hypoxia tolerance using a mutagenesis and overexpression screens to beg...

journal_title：Pediatric research

authors： Zhou D,Visk DW,Haddad GG

更新日期：2009-09-01 00:00:00

abstract：:LBW infants are at risk of iron deficiency (ID), which is associated with impaired nervous system development and may lead to prolonged auditory brainstem response (ABR) latencies. We hypothesized that iron supplementation shortens ABR latencies in marginally LBW (MLBW, 2000-2500 g) infants. In a randomized, controlle...

journal_title：Pediatric research

authors： Berglund SK,Westrup B,Haraldsson E,Engström B,Domellöf M

更新日期：2011-12-01 00:00:00

abstract：:To delineate the role of growth hormone (GH) in the development and function of the immune system, immunological parameters including quantitative immunoglobulins, T and B lymphocytes, phytohemagglutinin lymphoproliferative response and delayed hypersensitivity skin tests were studied in nine GH-deficient children pri...

journal_title：Pediatric research

authors： Abbassi V,Bellanti JA

更新日期：1985-03-01 00:00:00

abstract：:BackgroundHyperoxic lung injury is characterized by cellular damage from high oxygen concentrations that lead to an inflammatory response and it disrupts normal alveolarization in the developing newborn lung. Adenosine is a signaling molecule that is generated extracellularly by ecto-5'-nucleotidase (CD73) in response...

journal_title：Pediatric research

authors： Li H,Karmouty-Quintana H,Chen NY,Mills T,Molina J,Blackburn MR,Davies J

更新日期：2017-08-23 00:00:00

abstract：:In Chinese children with steroid-resistant nephrotic syndrome (SRNS), it was reported that NPHS2 mutation was detected in 4.3%, which was lower than that in Caucasians (10-30%). However, there were no data on WT1 mutation in nephrotic syndrome (NS), especially in early-onset NS of Chinese children. Thus, a study, whic...

journal_title：Pediatric research

authors： Li J,Ding J,Zhao D,Yu Z,Fan Q,Chen Y,Zhang H,Zhong X,Huang J,Yao Y,Xiao H

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:General movements (GMs) in infants occur as fidgety movements (FMs) between postterm 9 and 20 weeks. We aimed to evaluate FMs and motor repertoire in infants with cystic fibrosis (CF) and their relation with clinical findings. METHODS:Demographic and clinical characteristics were recorded. FMs and motor rep...

journal_title：Pediatric research

authors： Tekerlek H,Mutlu A,Inal-Ince D,Livanelioglu A,Kahraman A,Eryilmaz-Polat S,Karakaya J,Ozcelik U

更新日期：2020-07-27 00:00:00

abstract：:We recently demonstrated that recombinant hGH exacerbates renal functional and structural injury in chronic puromycin aminonucleoside (PAN) nephropathy, an experimental model of glomerular disease. Therefore, we examined whether recombinant human (rh) IGF-I is a safer alternative for the treatment of growth failure in...

journal_title：Pediatric research

authors： Trachtman H,Maesaka J,Futterweit S,Ma C,Valderrama E,Chan JC,Chan W

更新日期：1996-01-01 00:00:00

abstract：:Acute postasphyxial encephalopathy around the time of birth remains a major cause of death and disability. The possibility that hypothermia may be able to prevent or lessen asphyxial brain injury is a "dream revisited". In this review, a historical perspective is provided from the first reported use of therapeutic hyp...

journal_title：Pediatric research

authors： Gunn AJ,Laptook AR,Robertson NJ,Barks JD,Thoresen M,Wassink G,Bennet L

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Mevalonate kinase deficiency (MKD) is a rare genetic autoinflammatory disease caused by blocking of the enzyme mevalonate kinase in the pathway of cholesterol and isoprenoids. The pathogenic mechanism originating an immune response in MKD patients has not been clearly understood. METHODS:We investigated the...

journal_title：Pediatric research

authors： Marcuzzi A,Zanin V,Kleiner G,Monasta L,Crovella S

更新日期：2013-09-01 00:00:00

abstract：:Catecholamines (CA) are released from and resynthesized in the adrenal medulla in response to stress. In the mature animal, stimulus-secretion-synthesis coupling occurs through transsynaptic (neuronal) activity. In contrast, in the immature animal, before functional adrenal innervation, certain stressors (hypoglycemia...

journal_title：Pediatric research

authors： DeCristofaro JD,LaGamma EF

更新日期：1994-12-01 00:00:00

abstract：:The present study examined the extent to which abundance of the prolactin receptor (PRLR) and a range of primary mitochondrial proteins are influenced by either maternal nutrition and/or fetal number in adipose tissue. Pregnant sheep were control fed [consuming 100% of total metabolizable energy (ME) requirements (tak...

journal_title：Pediatric research

authors： Budge H,Dandrea J,Mostyn A,Evens Y,Watkins R,Sullivan C,Ingleton P,Stephenson T,Symonds ME

更新日期：2003-02-01 00:00:00

abstract：:Our objective was to determine the quantitative changes of individual triacylglycerol (TG) species in liver and carcass during early postnatal growth. Pregnant rats were killed at d 21 of pregnancy, and neonatal rats were killed at d 3 or 9 after birth. Quantitative changes in fatty acids and TG species of fetal/neona...

journal_title：Pediatric research

authors： Chen ZY,Cunnane SC

更新日期：1992-01-01 00:00:00