Serum lipids and lipoproteins at birth in a biracial population: the Bogalusa heart study.

Abstract:

:The lipid profile, total cholesterol, triglycerides, and lipoproteins (beta-, pre-beta-, and alpha-) of cord blood, is presented for 419 black and white infants (94% of the eligible population) born during an 18-month period in Bogalusa, Louisiana. At birth, white neonates of both sexes had higher average levels than black neonates of total cholesterol and beta-lipoproteins. White girls among the four race-sex groups had the highest cord blood levels of total cholesterol, beta-lipoproteins, and alpha-lipoproteins. Neither stress at delivery, birthweight, socioeconomic status, nor season of the year had an observable effect on any of the lipid or lipoprotein levels. The magnitude and direction of the relationships between the respective lipids and lipoproteins in cord blood were similar to those we have observed in preschool and school-aged children in the same community. Total cholesterol was highly correlated with both beta- and alpha-lipoproteins; triglycerides were correlated with pre-beta-lipoproteins but inversely with alpha-lipoproteins. These observations suggest that basic biochemical relationships are already established at birth.

journal_name

Pediatr Res

journal_title

Pediatric research

authors

Frerichs RR,Srinivasan SR,Webber LS,Rieth MC,Berenson GS

doi

10.1203/00006450-197808000-00011

subject

Has Abstract

pub_date

1978-08-01 00:00:00

pages

858-63

issue

8

eissn

0031-3998

issn

1530-0447

journal_volume

12

pub_type

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