Gestational changes in renal responsiveness to cortisol in the ovine fetus.

abstract：:Early childhood overweight and obesity have alarmingly increased over the years. Adulthood obesity is a well demonstrated significant independent predictor of cardiovascular risk (CVR) and/or mortality, which predisposes to the major components of metabolic syndrome (MS). Evidence of MS in obese children has been also...

journal_title：Pediatric research

authors： Aggoun Y

更新日期：2007-06-01 00:00:00

abstract：:Matrix metalloproteinases (MMP) are likely effectors of normal lung development, especially branching morphogenesis, angiogenesis, and extracellular matrix degradation. Because hyperoxia exposure (>95% O(2)) from d 4 to 14 in newborn rat pups leads to arrest of alveolarization and mimics newborn chronic lung disease, ...

journal_title：Pediatric research

authors： Hosford GE,Fang X,Olson DM

更新日期：2004-07-01 00:00:00

abstract：:We studied properties of saliva and of dental plaque which affect the caries process in an effort to understand the low prevalence of caries in patients with chronic renal failure. Plaque pH, before and following carbohydrate exposure, saliva pH, and saliva composition were evaluated in children and adolescents with c...

journal_title：Pediatric research

authors： Peterson S,Woodhead J,Crall J

更新日期：1985-08-01 00:00:00

abstract：:The purpose of this study was to investigate the effect of constant light in a neonatal care unit on the development of the sleep-and-wakefulness rhythm in preterm infants. Two groups of infants (57 preterm infants without other complications and 58 healthy term infants) were prospectively studied over infancy by a da...

journal_title：Pediatric research

authors： Shimada M,Segawa M,Higurashi M,Akamatsu H

更新日期：1993-02-01 00:00:00

abstract：INTRODUCTION:Very early preterm infants (VPIs) are exposed to unpredictable noise in neonatal intensive care units. Their ability to perceive moderate acoustic environmental changes has not been fully investigated. RESULTS:Physiological values of the 598 isolated sound peaks (SPs) that were 5-10 and 10-15 dB slow-resp...

journal_title：Pediatric research

authors： Kuhn P,Zores C,Pebayle T,Hoeft A,Langlet C,Escande B,Astruc D,Dufour A

更新日期：2012-04-01 00:00:00

abstract：:EBV has been associated with several malignancies in humans. EBV can also infect marmoset B lymphocytes, which, as opposed to human B cells, are permissive for lytic Epstein-Barr viral replication. Mice with a severe combined immunodeficiency phenotype (SCID mice) are extremely susceptible to EBV-induced lymphomagenes...

journal_title：Pediatric research

authors： Katz BZ,Salimi B,Saini U,McNamara JG,Eisen R

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Kawasaki disease (KD) is the most common systemic vasculitis syndrome primarily affecting medium-sized arteries, particularly the coronary arteries. Though KD may be associated with immunological problems, the involvement of microRNAs (miRs) has not been fully described. METHODS:We enrolled 23 KD patients a...

journal_title：Pediatric research

authors： Saito K,Nakaoka H,Takasaki I,Hirono K,Yamamoto S,Kinoshita K,Miyao N,Ibuki K,Ozawa S,Watanabe K,Bowles NE,Ichida F

更新日期：2016-09-01 00:00:00

abstract：:The age-related changes in fasting arterial levels of energy substrates and insulin were studied at birth and/or 6 wk in eleven baboon infants. In addition, the renal contribution to glucose release in the primate infant was estimated. Arterial blood glucose levels were similar in six fasted newborns and in nine faste...

journal_title：Pediatric research

authors： Levitsky LL,Paton JB,Fisher DE,Delannoy CW

更新日期：1980-08-01 00:00:00

abstract：:Mother's milk represents a foundational step in the proper development of newborn immunity. This is achieved, in part, through the action of numerous regulatory proteins such as soluble cluster of differentiation 14 (sCD14) found in significant quantities in human milk (~25-50 μg/mL). In adults, CD14 stimulates cytoki...

journal_title：Pediatric research

authors： Spencer WJ,Binette A,Ward TL,Davis LD,Blais DR,Harrold J,Mack DR,Altosaar I

更新日期：2010-12-01 00:00:00

abstract：:Serial plasma concentrations of immunoreactive 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), the stable hydration product of prostacyclin (PGI2), were measured with radioimmunoassay during the first month of life in 25 preterm infants with idiopathic respiratory distress syndrome (IRDS) and 38 preterm controls wi...

journal_title：Pediatric research

authors： Kääpä P,Koivisto M,Viinikka L,Ylikorkala O

更新日期：1982-10-01 00:00:00

abstract：:Previous studies have shown that early life stress in the form of intermittent maternal separation (MS) predisposes adult rats to develop stress-induced intestinal mucosal dysfunction and visceral hypersensitivity. However, the mechanism involved in the functional abnormalities is unclear. Our aim was to study immatur...

journal_title：Pediatric research

authors： Gareau MG,Jury J,Yang PC,MacQueen G,Perdue MH

更新日期：2006-01-01 00:00:00

abstract：:Escherichia coli which elaborate heat stable enterotoxin (ST) are a major cause of endemic diarrhea in infants. The reason(s) for this increased susceptibility of infants to ST-mediated diarrhea is unknown. We investigated the possibility that the immature (14 and 21 day old) rat small intestine is more sensitive to S...

journal_title：Pediatric research

authors： Cohen MB,Moyer MS,Luttrell M,Giannella RA

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PH) in patients with bronchopulmonary dysplasia (BPD) results from vasoconstriction and/or vascular remodeling, which can be regulated by mitogen-activated protein kinases (MAPKs). MAPKs are deactivated by dual-specificity phosphatases (DUSPs). We hypothesized that single-nucleotide p...

journal_title：Pediatric research

authors： Chen LL,Zmuda EJ,Talavera MM,Frick J,Brock GN,Liu Y,Klebanoff MA,Trittmann JK

更新日期：2020-01-01 00:00:00

abstract：:Apoptosis of CD4+ and CD8+ T cells has been shown in peripheral blood mononuclear cells (PBMCs) from HIV-infected adults analyzed after overnight culture. Because cell death may be an artifact of in vitro culture, and because there is little information on apoptosis in pediatric HIV disease, we undertook a cross-secti...

journal_title：Pediatric research

authors： Cotton MF,Ikle DN,Rapaport EL,Marschner S,Tseng PO,Kurrle R,Finkel TH

更新日期：1997-11-01 00:00:00

abstract：:Galactose metabolism was studied in human ovarian tissue obtained from 14 women controls between 21 and 72 y of age, and one 21-y-old galactosemic patient with hypergonadotrophic hypogonadism. Tissue slices were incubated with 1-14C-galactose, and labeled intermediates were analyzed by anion-exchange column chromatogr...

journal_title：Pediatric research

authors： Xu YK,Ng WG,Kaufman FR,Lobo RA,Donnell GN

更新日期：1989-02-01 00:00:00

abstract：:Meconium aspiration syndrome (MAS) is a serious condition in newborns, associated with a poorly characterized inflammatory reaction. The aim of this study was to investigate a possible role for complement in pulmonary pathophysiology and systemic inflammation in experimental MAS. MAS was induced by instillation of mec...

journal_title：Pediatric research

authors： Lindenskov PH,Castellheim A,Aamodt G,Saugstad OD,Mollnes TE

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Continuous and intermittent bolus orogastric feedings are strategies used in infants unable to tolerate normal feeds. METHODS:To determine the effects of feeding modality on protein synthesis in different tissues, neonatal pigs received a balanced formula by orogastric tube as an intermittent bolus feed eve...

journal_title：Pediatric research

authors： El-Kadi SW,Gazzaneo MC,Suryawan A,Orellana RA,Torrazza RM,Srivastava N,Kimball SR,Nguyen HV,Fiorotto ML,Davis TA

更新日期：2013-08-01 00:00:00

abstract：:Milk gangliosides inhibit Vibrio cholerae enterotoxin and Escherichia coli heat-labile enterotoxin. Human milk gangliosides showed considerably higher enterotoxin-inhibitory activity compared to bovine and formula milk gangliosides as measured in vitro by enzyme-linked immunosorbent assay and in vivo in rabbit small b...

journal_title：Pediatric research

authors： Laegreid A,Otnaess AB,Fuglesang J

更新日期：1986-05-01 00:00:00

abstract：:Necrotizing enterocolitis (NEC) is a devastating intestinal disease of premature infants. Maternal milk has been suggested to be partially protective against NEC; however, the mechanisms of this protection are not defined. The aim of this study was to examine the effect(s) of artificial feeding of rat milk (RM)-versus...

journal_title：Pediatric research

authors： Dvorak B,Halpern MD,Holubec H,Dvorakova K,Dominguez JA,Williams CS,Meza YG,Kozakova H,McCuskey RS

更新日期：2003-03-01 00:00:00

abstract：:Supine sleeping, recommended to prevent sudden infant death, should be started in the delivery hospital, but meets concern that neonates may exhibit more intermittent hypoxia in this position. We aimed to demonstrate that intermittent hypoxia is equally rare in supine and side position. We enrolled 609 term neonates i...

journal_title：Pediatric research

authors： Poets A,Urschitz MS,Poets CF

更新日期：2009-06-01 00:00:00

abstract：:Hypoxia and other adverse conditions are commonly encountered by rapidly growing cells. The RNA-binding protein RBM3 (RNA-binding motif protein 3), which is transcriptionally induced by low temperature and hypoxia, has recently been implicated in survival of colon cancer cells by mechanisms involving cyclooxygenase-2 ...

journal_title：Pediatric research

authors： Wellmann S,Truss M,Bruder E,Tornillo L,Zelmer A,Seeger K,Bührer C

更新日期：2010-01-01 00:00:00

abstract：:The presence of high concentrations of sodium in the sweat of patients with cystic fibrosis is widely accepted by all investigators as one of the most important manifestations of the genetic defect. However, the simple means of sweat collection utilized for diagnostic purposes has been extended to the biochemical and ...

journal_title：Pediatric research

authors： Sens DA,Simmons MA,Spicer SS

更新日期：1985-08-01 00:00:00

abstract：:A series of in vivo experiments is described in which [1-13C]phytanic acid was given as an oral substrate to a healthy subject and two patients showing an impairment in phytanic acid degradation, one with Refsum's disease and one with chondrodysplasia punctata. After intake of the substrate by the control in a dose of...

journal_title：Pediatric research

authors： ten Brink HJ,Schor DS,Kok RM,Stellaard F,Kneer J,Poll-The BT,Saudubray JM,Jakobs C

更新日期：1992-11-01 00:00:00

abstract：:Bubble continuous positive airway pressure (B-CPAP) applies small-amplitude, high-frequency oscillations in airway pressure (DeltaPaw) that may improve gas exchange in infants with respiratory disease. We developed a device, high-amplitude B-CPAP (HAB-CPAP), which provides greater DeltaPaw than B-CPAP provides. We stu...

journal_title：Pediatric research

authors： Diblasi RM,Zignego JC,Tang DM,Hildebrandt J,Smith CV,Hansen TN,Richardson CP

更新日期：2010-06-01 00:00:00

abstract：:The risk of pulmonary hemorrhage is increased in extremely low birth weight infants treated with surfactant. The pathogenesis of this increased risk is far from clear. We tested whether exposure of cell membranes to surfactant may lead to increased membrane permeability, hypothesizing that this process may contribute ...

journal_title：Pediatric research

authors： Findlay RD,Taeusch HW,David-Cu R,Walther FJ

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Some of the health advantages of breast-fed as compared to formula-fed infants have been suggested to be due to metabolic programming effects resulting from early nutrition. METHODS:In a prospective double-blinded randomized trial, 160 infants <2 mo of age were randomized to experimental formula (EF) with a...

journal_title：Pediatric research

authors： Timby N,Lönnerdal B,Hernell O,Domellöf M

更新日期：2014-10-01 00:00:00

abstract：:Human and ovine placental tissue homogenates were assayed for dipeptidase activity in vitro. Glycyl-L-leucine, L-leucyl glycine, glycyl-L-lysine, and L-lysyl glycine were hydrolyzed by placental homogenates. The pH optimum for the reaction was 8.0. The relationship between enzyme activity and concentration was linear ...

journal_title：Pediatric research

authors： Crandell SS,Adcock EW 3rd,Morriss FH Jr

更新日期：1981-04-01 00:00:00

abstract：:The incidence of allergic diseases has increased, and a relation between allergy and dietary fatty acids has been proposed. Modulation of the maternal immune function during pregnancy may have an impact on future clinical outcomes in the child. The aim of this study was to determine the effects of omega (omega)-3 long...

journal_title：Pediatric research

authors： Warstedt K,Furuhjelm C,Duchén K,Fälth-Magnusson K,Fagerås M

更新日期：2009-08-01 00:00:00

abstract：:Children with inborn errors of urea synthesis who survive neonatal hyperammonemic coma commonly exhibit cognitive deficits and neurologic abnormalities. Yet, there is evidence that ammonia is not the only neurotoxin. Hyperammonemia appears to induce a number of neurochemical alterations. In rodent models of hyperammon...

journal_title：Pediatric research

authors： Robinson MB,Heyes MP,Anegawa NJ,Gorry E,Djali S,Mellits ED,Batshaw ML

更新日期：1992-10-01 00:00:00

abstract：:Evidence is inconsistent or poorly understood for links between polychlorinated biphenyls (PCBs), 1,1'-dichloro-2,2'-bis(4-chlorophenyl)ethylene (DDE), and organophosphate (OP) pesticides and adverse pregnancy outcomes, although they are known developmental toxicants. We measured biomarkers of maternal exposure to DDE...

journal_title：Pediatric research

authors： Wolff MS,Engel S,Berkowitz G,Teitelbaum S,Siskind J,Barr DB,Wetmur J

更新日期：2007-02-01 00:00:00