Alpha 1-antitrypsin phenotype: transient cathodal shift in serum of infant girl with urinary cytomegalovirus and fatty liver.

abstract：:This study tested the hypothesis that the sexually dimorphic adrenocortical response to stress is already established before birth. Chronically instrumented late gestation pregnant sheep carrying 16 male and 15 female age-matched singleton fetuses were subjected to an acute episode of hypoxic stress. Maternal and feta...

journal_title：Pediatric research

authors： Giussani DA,Fletcher AJ,Gardner DS

更新日期：2011-02-01 00:00:00

abstract：INTRODUCTION:To examine the immune-modulatory effects of probiotics during early infancy, Bifidobacterium breve M-16V (B. breve) was administered to rat pups during the newborn or weaning period, and the expression of inflammatory genes was investigated using a cDNA microarray and real-time PCR. RESULTS:After B. breve...

journal_title：Pediatric research

authors： Ohtsuka Y,Ikegami T,Izumi H,Namura M,Ikeda T,Ikuse T,Baba Y,Kudo T,Suzuki R,Shimizu T

更新日期：2012-01-01 00:00:00

abstract：:Leukotrienes C4 and D4 and thromboxane A2 are potent vasoconstrictors that may mediate pulmonary vasoconstriction in many clinical situations. There is a complex interaction among leukotrienes and thromboxane A2, because inhibition of thromboxane synthesis prevents some of the hemodynamic effects of exogenous leukotri...

journal_title：Pediatric research

authors： Soifer SJ,Schreiber MD,Heymann MA

更新日期：1989-08-01 00:00:00

abstract：:C3H/HeJ mice develop an increase in terminal air space area detectable by postnatal d 14 that persists into adulthood compared with strain-matched controls (C3H/SnJ, C3H/OuJ). Morphometric quantification revealed a 50% increase in terminal air space area by postnatal d 14 and a 2.3-fold increase by 2 mo of age in C3H/...

journal_title：Pediatric research

authors： Sampath V,Davis K,Senft AP,Richardson TR,Kitzmiller JA,Berclaz PY,Korfhagen TR

更新日期：2006-12-01 00:00:00

abstract：:Soft bedding has been shown in epidemiologic studies to increase the risk for sudden, unexpected death in prone-sleeping infants. We compared the physical properties of conventional bedding to bedding from two sources: 1) bedding that covered the airways of victims of sudden infant death syndrome (SIDS) lying prone an...

journal_title：Pediatric research

authors： Kemp JS,Nelson VE,Thach BT

更新日期：1994-07-01 00:00:00

abstract：:EBV has been associated with several malignancies in humans. EBV can also infect marmoset B lymphocytes, which, as opposed to human B cells, are permissive for lytic Epstein-Barr viral replication. Mice with a severe combined immunodeficiency phenotype (SCID mice) are extremely susceptible to EBV-induced lymphomagenes...

journal_title：Pediatric research

authors： Katz BZ,Salimi B,Saini U,McNamara JG,Eisen R

更新日期：1994-10-01 00:00:00

abstract：:Twelve critically ill neonates mechanically ventilated for respiratory failure (mean weight 1.33 kg, mean gestation 31 wk) were studied to quantitate the effects of radiant power from a radiant warming device, body weight, and body surface area on insensible water loss. Radiant power density (Mw/cm2) was measured usin...

journal_title：Pediatric research

authors： Baumgart S,Engle WD,Fox WW,Polin RA

更新日期：1981-12-01 00:00:00

abstract：:The flavin-containing monooxygenases (FMOs) are important for the metabolism of numerous therapeutics and toxicants. Six mammalian FMO genes (FMO1-6) have been identified, each exhibiting developmental and tissue- and species-specific expression patterns. Previous studies demonstrated that human hepatic FMO1 is restri...

journal_title：Pediatric research

authors： Koukouritaki SB,Simpson P,Yeung CK,Rettie AE,Hines RN

更新日期：2002-02-01 00:00:00

abstract：:Continuous EEG monitoring has not been used widely in neonatal intensive care, especially in the care of extremely premature infants, probably in part because of a lack of a reliable quantitative method. The purpose of this study was to quantify the EEG of the very premature infants just after birth by using spectral ...

journal_title：Pediatric research

authors： Victor S,Appleton RE,Beirne M,Marson AG,Weindling AM

更新日期：2005-03-01 00:00:00

abstract：:We have previously demonstrated that enterally administered heparin-binding EGF-like growth factor (HB-EGF) produced in Escherichia coli decreases the incidence and severity of intestinal injury in a neonatal rat model of necrotizing enterocolitis (NEC). In preparation for upcoming human clinical trials, large-scale p...

journal_title：Pediatric research

authors： Radulescu A,Zorko NA,Yu X,Besner GE

更新日期：2009-04-01 00:00:00

abstract：:The effect of intrauterine growth retardation (IUGR) on cerebral and adrenal monoamine metabolism was studied in the fetuses of eight nulliparous rat dams after unilateral uterine artery ligation on d 18 of gestation. On d 22 (term = 23 d), four dams were subjected to normoxia and four to hypoxia (10% O2) for 58 min w...

journal_title：Pediatric research

authors： Thordstein M,Hedner T

更新日期：1992-02-01 00:00:00

abstract：:Sleep organization of infants may be influenced by differences in nutrient intakes from human milk and formula. Because sleep/awake and sleep stage patterns affect energy expenditure, we hypothesized that differences in sleep organization between breast-fed and formula-fed infants might account in part for differences...

journal_title：Pediatric research

authors： Butte NF,Jensen CL,Moon JK,Glaze DG,Frost JD Jr

更新日期：1992-11-01 00:00:00

abstract：:Insulin is a potent mitogen for many cell types in vitro. During tissue culture, supraphysiological concentrations of insulin are necessary to promote cell replication in connective or musculoskeletal tissues. Insulin promotes the growth of these cells by binding, with low affinity, to the type I insulin-like growth f...

journal_title：Pediatric research

authors： Hill DJ,Milner RD

更新日期：1985-09-01 00:00:00

abstract：:Sodium deficiency is associated with decreased muscle growth and protein synthesis. We investigated the influence of diet-induced sodium deficiency on the rate and extent of compensatory growth of the right lung after left pneumonectomy in young rats of 83 +/- 1 g body weight. Starting 1 wk before surgery, all rats we...

journal_title：Pediatric research

authors： Gallaher KJ,Wolpert E,Wassner S,Rannels DE

更新日期：1990-11-01 00:00:00

abstract：:Television viewing (TVV) is considered a contributing factor to the development of childhood obesity yet it is unclear whether obesity results, in part, from increased energy intake during TVV. The objective of this study was to determine the effect of TVV on food intake (FI) of boys at a meal and its effect on calori...

journal_title：Pediatric research

authors： Bellissimo N,Pencharz PB,Thomas SG,Anderson GH

更新日期：2007-06-01 00:00:00

abstract：:Our aim was to compare white matter (WM) microstructure in preterm infants with and without punctate WM lesions on MRI using tract-based spatial statistics (TBSS) and probabilistic tractography. We studied 23 preterm infants with punctate lesions, median GA at birth 30 (25-35) wk, and 23 GA- and sex-matched preterm co...

journal_title：Pediatric research

authors： Bassi L,Chew A,Merchant N,Ball G,Ramenghi L,Boardman J,Allsop JM,Doria V,Arichi T,Mosca F,Edwards AD,Cowan FM,Rutherford MA,Counsell SJ

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Volatile organic compounds (VOCs) are hydrocarbons that originate within different healthy and diseased tissues. VOCs can be secreted into the circulation and then excreted in the urine and faeces. In the lungs, VOCs are locally produced and can be detected in exhaled breath. VOCs can be identified using non...

journal_title：Pediatric research

authors： Wright H,Bannaga AS,Iriarte R,Mahmoud M,Arasaradnam RP

更新日期：2020-03-02 00:00:00

abstract：:Epithelial hyperplasia is an early feature of the renal and biliary lesions in autosomal recessive polycystic kidney disease (ARPKD). To explore the cellular basis of this hyperplasia we isolated, cultured, and characterized biliary tract epithelium from common bile duct explants of mice with ARPKD (the BPK mouse) and...

journal_title：Pediatric research

authors： Nauta J,Sweeney WE,Rutledge JC,Avner ED

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:In infants admitted to an ICU with respiratory failure, there is an association between the ratio of CD8+ to CD4+ T cells within the upper respiratory tract and disease severity. Whether this ratio is associated with respiratory disease severity within children presenting to a pediatric emergency department ...

journal_title：Pediatric research

authors： Cosgrove PR,Redhu NS,Tang Y,Monuteaux MC,Horwitz BH

更新日期：2021-01-27 00:00:00

abstract：:Prenatal exposure to infection and subsequent inflammatory responses have been implicated in the etiology of schizophrenia and autism. In this review, we summarize current evidence from human and animal studies supporting the hypothesis that the pathogenesis of these two disorders is linked via exposure to inflammatio...

journal_title：Pediatric research

authors： Meyer U,Feldon J,Dammann O

更新日期：2011-05-01 00:00:00

abstract：:Wu and colleagues analyzed the placental pathology from a subset of the neonates in the NEATO trial who had reports available and correlated the placental pathology findings with outcomes. This study highlights the importance of placental pathology, and its potential to bring precision medicine to critically-ill neona...

journal_title：Pediatric research

authors： Jantzie LL,Robinson S

更新日期：2020-04-01 00:00:00

abstract：INTRODUCTION:Data regarding neonatal arterial ischemic stroke (NAIS) topography are still sparse and inaccurate. Despite the importance of locating NAIS to predict the long-term outcome of neonates, a map of arterial territories is not yet available. Our aim was therefore to generate the first three-dimensional map of ...

journal_title：Pediatric research

authors： Núñez C,Arca G,Agut T,Stephan-Otto C,García-Alix A

更新日期：2020-06-01 00:00:00

abstract：:The aim of the present study was to determine the proportion of gamma/delta T-lymphocytes and CD16/CD56 (CD3- and CD3+) cells in the peripheral blood of children and adolescents with Graves' disease (GD; n = 27; mean age, 15.5 +/- 5.1 y) and nontoxic nodular goiter (NTNG; n = 25; mean age, 15.2 +/- 5.7 y), in comparis...

journal_title：Pediatric research

authors： Bossowski A,Urban M,Stasiak-Barmuta A

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Heterozygous ATP-binding-cassette subfamily A member 3 (ABCA3) mutations are associated with neonatal respiratory complications. In an adult murine model, we investigated whether Abca3 haploinsufficiency is a predisposing factor for lung injury induced by hyperoxia or mechanical ventilation. METHODS:Abca3 h...

journal_title：Pediatric research

authors： Herber-Jonat S,Mittal R,Huppmann M,Hammel M,Liebisch G,Yildirim AÖ,Eickelberg O,Schmitz G,Hrabé de Angelis M,Flemmer AW,Holzinger A

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:This study aimed to assess cortical gray matter growth and maturation in neonates with congenital heart disease (CHD). METHODS:Thirty-one (near) term neonates with severe CHD (8 univentricular heart malformation (UVH), 21 d-transposition of great arteries (d-TGA) and 2 aortic coarctation) underwent cerebral...

journal_title：Pediatric research

authors： Claessens NH,Moeskops P,Buchmann A,Latal B,Knirsch W,Scheer I,Išgum I,de Vries LS,Benders MJ,von Rhein M

更新日期：2016-11-01 00:00:00

abstract：:Severely birth-asphyxiated human infants develop delayed ("secondary") cerebral energy failure, which carries a poor prognosis, during the first few days of life. This study tested the hypothesis that i.v. magnesium sulfate (MgSO4) after severe transient cerebral hypoxia-ischemia decreases the severity of delayed ener...

journal_title：Pediatric research

authors： Penrice J,Amess PN,Punwani S,Wylezinska M,Tyszczuk L,D'Souza P,Edwards AD,Cady EB,Wyatt JS,Reynolds EO

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:We examined the extent of fetal lung hypoplasia and lung maturation using the amniotic lamellar body count (LBC) in congenital diaphragmatic hernia (CDH). METHODS:We obtained 30 amniotic fluid samples from human CDH cases during cesarean section. We assessed LBC, magnetic resonance imaging (MRI), and ultras...

journal_title：Pediatric research

authors： Watanabe Y,Tsuda H,Kotani T,Sumigama S,Mano Y,Hayakawa M,Sato Y,Kikkawa F

更新日期：2013-03-01 00:00:00

abstract：:Few data exist regarding resuscitation of hypovolemic shock in infants, and alternative strategies such as vasopressor therapy merit further evaluation. However, the effects of norepinephrine on cerebral perfusion and oxygenation during hemorrhagic shock in the pediatric population are still unclear. Eight anesthetize...

journal_title：Pediatric research

authors： Meybohm P,Renner J,Boening A,Cavus E,Gräsner JT,Grünewald M,Scholz J,Bein B

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Caffeine is a nonspecific adenosine receptor antagonist used in premature neonates to treat apnea of prematurity. While its use may reduce the incidence of bronchopulmonary dysplasia (BPD), the precise mechanisms remain unknown. Evidence of increased adenosine levels are noted in chronic lung diseases includ...

journal_title：Pediatric research

authors： Dayanim S,Lopez B,Maisonet TM,Grewal S,Londhe VA

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:To understand the increased susceptibility of preterm neonates to infection. METHODS:A murine listeriosis model using immunohistochemistry, microarray technology, and real-time polymerase chain reaction (PCR). RESULTS:We report that recombinant serum amyloid A (SAA) administered prophylactically 18 h befor...

journal_title：Pediatric research

authors： Hawkins JS,Wu Q,Wang Y,Lu CY

更新日期：2013-12-01 00:00:00