Sleep organization and energy expenditure of breast-fed and formula-fed infants.

abstract：:Newborn piglets exposed to acute hypoxia-ischemia (HI) received i.v. cannabidiol (HI + CBD) or vehicle (HI + VEH). In HI + VEH, 72 h post-HI brain activity as assessed by amplitude-integrated EEG (aEEG) had only recovered to 42 ± 9% of baseline, near-infrared spectroscopy (NIRS) parameters remained lower than normal, ...

journal_title：Pediatric research

authors： Lafuente H,Alvarez FJ,Pazos MR,Alvarez A,Rey-Santano MC,Mielgo V,Murgia-Esteve X,Hilario E,Martinez-Orgado J

更新日期：2011-09-01 00:00:00

abstract：:Brain injury remains one of the major unsolved problems in neonatal care, with survivors at high risk of lifelong neurodisability. It is unlikely that a single intervention can ameliorate neonatal brain injury, given the complex interaction between pathological processes, developmental trajectory, genetic susceptibili...

journal_title：Pediatric research

authors： Austin T

更新日期：2019-12-18 00:00:00

abstract：:Nutrition in early life, growth, and subsequent health over a lifetime are significantly interrelated. The aim of this study was to assess body composition changes in exclusively breast-fed infants from birth up to 6 mo of age. An observational, prospective, cohort study was conducted. Fifty-nine full-term, healthy, e...

journal_title：Pediatric research

authors： Roggero P,Giannì ML,Orsi A,Piemontese P,Amato O,Liotto N,Morlacchi L,Taroni F,Fields DA,Catalano PM,Mosca F

更新日期：2010-12-01 00:00:00

abstract：:Pulmonary hypoplasia has been associated with absent or hypoplastic pulmonary artery in four cases in humans. Despite these reports, the effects of decreased pulmonary arterial flow on fetal lung growth have not been adequately studied. This study defines the effects of left pulmonary artery (LPA) ligation on fetal lu...

journal_title：Pediatric research

authors： Wallen LD,Perry SF,Alston JT,Maloney JE

更新日期：1990-02-01 00:00:00

abstract：:The effect of hypoxia-ischemia (HI) on IL-1, and IL-6 bioactivity in relation to expression of IL-1 alpha, IL-1 beta, and IL-6 mRNA was studied, and the neuroprotective efficacy of IL-1 receptor antagonist (IL-1ra) was evaluated in neonatal rats. HI was induced in 7-d-old rats by unilateral carotid artery ligation and...

journal_title：Pediatric research

authors： Hagberg H,Gilland E,Bona E,Hanson LA,Hahin-Zoric M,Blennow M,Holst M,McRae A,Söder O

更新日期：1996-10-01 00:00:00

abstract：:The rat undergoes profound maturational changes in the intestinal structure and function during the third week of its life. To investigate the role of peripheral glucocorticoid metabolism in this process, we studied the postnatal maturation of intestinal structure and function. The peripheral metabolism of glucocortic...

journal_title：Pediatric research

authors： Pácha J,Vagnerová R,Bryndová J

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Hurricane Maria struck Puerto Rico on 20 September 2017 causing catastrophic devastation. Prolonged shortage of food had been a substantial challenge to the residents after Maria. Experiencing food insecurity in utero has been associated with negative health outcomes later in life. We aim to examine whether ...

journal_title：Pediatric research

authors： Wang L,de Ángel Solá D,Acevedo Flores M,Schriefer A,Wang L,Gerónimo López K,Chang A,Warner B,Shan L,Holtz LR,Rosario Matos N

更新日期：2020-12-01 00:00:00

abstract：:Data are scarce regarding mineral bioavailability from human milk in older infants who may also be receiving solid foods (beikost). We measured the absorption of Ca, Zn, and Fe in 14 healthy, nonanemic 5-7-mo-old breast-fed infants whose mothers milk was extrinsically labeled with stable isotopes (44Ca, 70Zn, and 58Fe...

journal_title：Pediatric research

authors： Abrams SA,Wen J,Stuff JE

更新日期：1997-03-01 00:00:00

abstract：:Neurogenesis persists throughout life in the rodent subventricular zone (SVZ) and increases in the adult after brain injury. In this study, postnatal day 7 (P7) rats underwent right carotid artery ligation followed by 8% O2 exposure for 90 min, a lesioning protocol that resulted in ipsilateral forebrain hypoxic-ischem...

journal_title：Pediatric research

authors： Ong J,Plane JM,Parent JM,Silverstein FS

更新日期：2005-09-01 00:00:00

abstract：:Previous studies have demonstrated that myocardial function changes during mammalian perinatal development. The purpose of this study was to evaluate the subcellular basis underlying the slower relaxation in the developing heart by examining perinatal changes in sarcoplasmic reticulum (SR) function, and in SR Ca2+ pum...

journal_title：Pediatric research

authors： Fisher DJ,Tate CA,Phillips S

更新日期：1992-05-01 00:00:00

abstract：:Perinatal brain injury is a leading cause of death and disability in young children. Recent advances in obstetrics, reproductive medicine and neonatal intensive care have resulted in significantly higher survival rates of preterm or sick born neonates, at the price of increased prevalence of neurological, behavioural ...

journal_title：Pediatric research

authors： Bendix I,Hadamitzky M,Herz J,Felderhoff-Müser U

更新日期：2019-01-01 00:00:00

abstract：:To investigate the detailed pattern of change in circulating gonadotropin and testosterone concentrations around the onset of puberty and to determine the temporal relationship between the gonadotropin and testosterone secretion, plasma gonadotropin and testosterone were measured at 20-min intervals for 24 h in 21 nor...

journal_title：Pediatric research

authors： Goji K,Tanikaze S

更新日期：1993-08-01 00:00:00

abstract：:An increase in polymorphonuclear leukocytes (PMNs) and proinflammatory chemokines, such as IL-8 and macrophage inflammatory protein-1 alpha (MIP), are found in the airways during early stages of bronchopulmonary dysplasia. We determined whether IL-10 produces a dose-related inhibition of proinflammatory chemokine rele...

journal_title：Pediatric research

authors： Tryzmel J,Miskolci V,Castro-Alcaraz S,Vancurova I,Davidson D

更新日期：2003-09-01 00:00:00

abstract：:Antibodies of restricted specificity have been identified in the human in response to certain antigens. The present study analyzed tetanus and diphtheria antitoxins isolated from selected human sera and suggested a restricted response in antibody production to each of these antigens. Purified antibodies from eight ser...

journal_title：Pediatric research

authors： Nathenson G,Litwin SD

更新日期：1977-12-01 00:00:00

abstract：:Lipase activities were measured at pH 4 and pH 8 in the placentas of rats made diabetic by streptozotocin treatment and also in the placentas of women classified as having 1) impaired glucose tolerance or type 2 diabetes, 2) type 1 diabetes with no associated vascular complication, and 3) type 1 diabetes with associat...

journal_title：Pediatric research

authors： Kaminsky S,Sibley CP,Maresh M,Thomas CR,D'Souza SW

更新日期：1991-12-01 00:00:00

abstract：:New information is emerging concerning the influence of environmental factors (e.g., viruses, pollutants, nutrients) on fetal lung development and the prenatal modulation of cellular and molecular effectors essential to the control of airway function, which may shed new light into the pathogenesis of chronic obstructi...

journal_title：Pediatric research

authors： Piedimonte G,Harford TJ

更新日期：2020-01-01 00:00:00

abstract：:Our aim was to compare white matter (WM) microstructure in preterm infants with and without punctate WM lesions on MRI using tract-based spatial statistics (TBSS) and probabilistic tractography. We studied 23 preterm infants with punctate lesions, median GA at birth 30 (25-35) wk, and 23 GA- and sex-matched preterm co...

journal_title：Pediatric research

authors： Bassi L,Chew A,Merchant N,Ball G,Ramenghi L,Boardman J,Allsop JM,Doria V,Arichi T,Mosca F,Edwards AD,Cowan FM,Rutherford MA,Counsell SJ

更新日期：2011-06-01 00:00:00

abstract：:The purpose of this investigation was twofold: (1) to identify and characterize the enzymatic ATP hydrolysis system of epithelial cilia, and (2) to develop a quantitative, biochemical test for the ciliotoxic cystic fibrosis (CF) factor based on inhibition of ATP utilization by ciliary preparations. Our rationale for s...

journal_title：Pediatric research

authors： Farrell PM,Fox GN,Spicer SS

更新日期：1976-02-01 00:00:00

abstract：:BackroundMicrocephaly can either be isolated or it may coexist with other neurological entities and/or multiple congenital anomalies, known as syndromic microcephaly. Although many syndromic cases can be classified based on the characteristic phenotype, some others remain uncertain and require further investigation. T...

journal_title：Pediatric research

authors： Tsoutsou E,Tzetis M,Giannikou K,Braoudaki M,Mitrakos A,Amenta S,Selenti N,Kanavakis E,Zafeiriou D,Kitsiou-Tzeli S,Fryssira H

更新日期：2017-08-01 00:00:00

abstract：:N-formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP) and N-formyl-L-methionyl-L-phenylalanine (FMP) were used to investigate neutrophil (PMN) aggregation. Neutrophils were isolated from healthy adult volunteers and term newborn cord blood. Neutrophil aggregation was measured after the addition of FMLP and FMP. Adult P...

journal_title：Pediatric research

authors： Olson TA,Ruymann FB,Cook BA,Burgess DP,Henson SA,Thomas PJ

更新日期：1983-12-01 00:00:00

abstract：:Neurological injury is the primary lethal mechanism of injury in children, and the primary etiology of long-term disability after trauma. Laboratories and clinical/translational teams have sought to develop stem/progenitor cell therapies to improve recovery in a clinical setting in which there is no significant repara...

journal_title：Pediatric research

authors： Cox CS Jr

更新日期：2018-01-01 00:00:00

abstract：:Phagocytosis of apoptotic cells, e.g., neutrophils, by monocytes is essential for resolution of inflammation. Delayed removal leads to secondary necrosis, perpetuating inflammation, and tissue destruction. Common histologic features in neonatal chronic inflammatory disorders are an accumulation of apoptotic cells in i...

journal_title：Pediatric research

authors： Gille C,Steffen F,Lauber K,Keppeler H,Leiber A,Spring B,Poets CF,Orlikowsky TW

更新日期：2009-11-01 00:00:00

abstract：:Fetal dermal wounds heal scarlessly and with a minimal inflammatory response. When a robust inflammatory response is induced at the site of fetal dermal wounds by the application of cytokines, healing results in fibrosis. To test the hypothesis that the reduced inflammatory response in fetal wounds is due to impaired ...

journal_title：Pediatric research

authors： Olutoye OO,Zhu X,Cass DL,Smith CW

更新日期：2005-12-01 00:00:00

abstract：:Respiratory distress syndrome (RDS) due to surfactant deficiency is the most common cause of respiratory failure in preterm infants. Tremendous progress has been made since the original description that surfactant deficiency is the major cause of RDS. Surfactant therapy has been extensively studied in preterm infants ...

journal_title：Pediatric research

authors： Sardesai S,Biniwale M,Wertheimer F,Garingo A,Ramanathan R

更新日期：2017-01-01 00:00:00

abstract：:In the fetal rat, nitrofen induces congenital diaphragmatic hernia (CDH) and pulmonary vascular remodeling similar to what is observed in the human condition. Airway hyperactivity is common in infants with CDH and attributed to the ventilator-induced airway damage. The purpose of this study was to test the hypothesis ...

journal_title：Pediatric research

authors： Belik J,Davidge ST,Zhang W,Pan J,Greer JJ

更新日期：2003-05-01 00:00:00

abstract：:Bacterial sepsis is a relatively common problem in the neonatal period, particularly among prematurely delivered infants. The newborn rat has been widely used as a model for sepsis neonatorum, and in that model incomplete development of the neutrophil system has been postulated to be an important factor predisposing n...

journal_title：Pediatric research

authors： Christensen RD,Rothstein G

更新日期：1984-07-01 00:00:00

abstract：:The flavin-containing monooxygenases (FMOs) are important for the metabolism of numerous therapeutics and toxicants. Six mammalian FMO genes (FMO1-6) have been identified, each exhibiting developmental and tissue- and species-specific expression patterns. Previous studies demonstrated that human hepatic FMO1 is restri...

journal_title：Pediatric research

authors： Koukouritaki SB,Simpson P,Yeung CK,Rettie AE,Hines RN

更新日期：2002-02-01 00:00:00

abstract：:A new animal experimental model of human neuroblastoma is described. The model involves xenotransplantation of a poorly differentiated human neuroblastoma cell line (SH-SY5Y) to the subcutaneous tissue in the hind leg of nude rats (WAG mu/rnu). Injection of 20 million cells suspended in 0.2 mL of medium in each hind l...

journal_title：Pediatric research

authors： Wassberg E,Påhlman S,Westlin JE,Christofferson R

更新日期：1997-03-01 00:00:00

abstract：:After an initial postnatal diuresis, neonates are in positive sodium balance. Because atrial natriuretic peptide (ANP) contributes to sodium homeostasis, this study was designed to evaluate the maturational effects of increased dietary sodium intake on cardiac ANP production. Preweaned Sprague-Dawley rat pups were art...

journal_title：Pediatric research

authors： Muchant DG,Belmonte DC,Garmey MJ,Baertschi AJ,Pence RA,Chevalier RL

更新日期：1995-03-01 00:00:00

abstract：:Growth hormone (GH) regulates growth and development in the postnatal period but lacks somatotropic activity in the fetus. In contrast, the placental hormone placental lactogen (PL) stimulates amino acid transport, DNA synthesis, and somatomedin production in isolated fetal tissues, suggesting that PL may function as ...

journal_title：Pediatric research

authors： Fowlkes J,Freemark M

更新日期：1992-08-01 00:00:00