Feasibility of long-term continuous EEG monitoring during the first days of life in preterm infants: an automated quantification of the EEG activity.

abstract：:Essential fatty acid deficiency (EFAD) occurs in infants fed fat-free mixtures of glucose and amino acids. Although infusion of lipid emulsion rapidly reverses clinical symptoms, little is known about effects on tissue fatty acids. To study this question, five groups (n = 4/group) of neonatal pigs were studied. Three ...

journal_title：Pediatric research

authors： Andersen DW,Filer LJ Jr,Stegink LD

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:Following our clinical observation of tonic responses in response to the knee jerk in infants at very high risk for cerebral palsy (VHR infants), we systematically studied tonic responses, clonus, and reflex irradiation. We questioned (i) whether these responses occurred more often in VHR infants than in typ...

journal_title：Pediatric research

authors： Hamer EG,Dijkstra LJ,Hooijsma SJ,Zijdewind I,Hadders-Algra M

更新日期：2016-09-01 00:00:00

abstract：:Long chain polyunsaturated fatty acids (LCPUFA)seem to be the most trophic macronutrients in inducing intestinal adaptation in adult short bowel syndrome (SBS), although their effects on intestinal adaptation in infants with SBS remain unknown.It is hypothesized that a high fat diet enriched with n-3 LCPUFA derived fr...

journal_title：Pediatric research

authors： Yang Q,Kock ND

更新日期：2010-09-01 00:00:00

abstract：:The ability of erythrocytes from newborn babies and adults to maintain reduced glutathione levels during oxidative stress was studied. In vitro incubation of erythrocytes with H2O2, with or without inactivation of catalase, caused a rapid depletion of reduced glutathione (GSH) and concomitant accumulation of oxidized ...

journal_title：Pediatric research

authors： Clahsen PC,Moison RM,Holtzer CA,Berger HM

更新日期：1992-10-01 00:00:00

abstract：:A method is developed for the detection of homozygotes and heterozygote carriers of Niemann-Pick disease type A by employing a high performance liquid chromatography (HPLC) technique for the measurement of sphingomyelin (SP) as well as for the assay of the enzyme sphingomyelinase (SPase) in skin fibroblasts and amniot...

journal_title：Pediatric research

authors： Jungalwala FB,Milunsky A

更新日期：1978-05-01 00:00:00

abstract：:Medium chain acyl-CoA dehydrogenase deficiency (MCAD) is a defect in the mitochondrial oxidation of fatty acids. The disorder typically presents with episodes of vomiting and hypoglycemia, sometimes with changes in mental status and hepatic failure. These Reye's-like features may culminate in coma and death. Stress, i...

journal_title：Pediatric research

authors： Ziadeh R,Hoffman EP,Finegold DN,Hoop RC,Brackett JC,Strauss AW,Naylor EW

更新日期：1995-05-01 00:00:00

abstract：:Functional disturbances in microcirculation in juvenile type 1 diabetes (T1D) are believed to underlie, in part, the later occurrence of cardiovascular complications. Some epidemiologic studies suggested greater risk of microvascular complications in those with T1D-risk genotypes of human leukocyte antigen (HLA). We i...

journal_title：Pediatric research

authors： Odermarsky M,Lernmark A,Truedsson L,Liuba P

更新日期：2008-04-01 00:00:00

abstract：:Concanavalin A surface receptors were detected on brush border enterocytes from child intestinal biopsies by the concanavalin A-peroxidase method. On electron microscopy, these receptors appeared as electron-dense deposits, located on a band running along the innermost part of the brush border membrane glycocalyx. In ...

journal_title：Pediatric research

authors： Vasmant D,Feldmann G,Fontaine JL

更新日期：1982-06-01 00:00:00

abstract：:In muscle, sepsis reduces protein synthesis (MPS) by restraining translation in neonates and adults. Even though protein accretion decreases with development as neonatal MPS rapidly declines by maturation, the changes imposed by development on the sepsis-associated decrease in MPS have not been described. Pigs at 7 an...

journal_title：Pediatric research

authors： Orellana RA,Wilson FA,Gazzaneo MC,Suryawan A,Davis TA,Nguyen HV

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Cognitive impairment has been documented in adult diabetes but is unclear in pediatric diabetes. No study had been conducted to explore the relationship between attention-deficit/hyperactivity disorder (ADHD) and diabetes. Using a population-based data set, we aimed to examine the association between ADHD an...

journal_title：Pediatric research

authors： Chen HJ,Lee YJ,Yeh GC,Lin HC

更新日期：2013-04-01 00:00:00

abstract：:Newborn Sprague-Dawley rat pups were found to have reduced net tubular reclamation of the beta-amino acid taurine in vivo. The reabsorption of this compound increased between the 2nd and 4th week of life and the excreted taurine fell despite a rise in glomerular filtration rate indicative of increased transport with m...

journal_title：Pediatric research

authors： Chesney RW,Jax DK

更新日期：1979-07-01 00:00:00

abstract：:Biotin responsive multiple carboxylase deficiency was suspected in a third trimester conceptus on the basis of enzymatic confirmation in fibroblasts cultured from an earlier sibling who suffered a demise in the immediate neonatal period. Maternal urinary organic acid profile was normal throughout the final 4 wk of pre...

journal_title：Pediatric research

authors： Roth KS,Yang W,Allan L,Saunders M,Gravel RA,Dakshinamurti K

更新日期：1982-02-01 00:00:00

abstract：:Pulmonary surfactant proteins SP-B and SP-C were isolated from lavage fluids of bovine lungs and recombined (lipid/proteins, 9/1, wt/wt) with dipalmitoyl phosphatidylcholine for testing in vitro and in surfactant-deficient adult rats. Using a pulsating bubble surfactometer, we found that inflation pressures of bubbles...

journal_title：Pediatric research

authors： Smith GB,Taeusch HW,Phelps DS,Keough KM

更新日期：1988-05-01 00:00:00

abstract：:We investigated the developmental changes in the pattern of urinary metabolites of theophylline, a substrate for CYP1A2, to study when CYP1A2, which is absent in the perinatal period, fully develops during childhood. The urinary ratios of three metabolites (1-methyluric acid, 3-methylxanthine, and 1,3-dimethyluric aci...

journal_title：Pediatric research

authors： Tateishi T,Asoh M,Yamaguchi A,Yoda T,Okano YJ,Koitabashi Y,Kobayashi S

更新日期：1999-01-01 00:00:00

abstract：:Oxidant stress has been implicated as playing a role in the pathogenesis of cholestatic liver injury. The objective of this study was to determine whether the xanthine oxidase/xanthine dehydrogenase enzyme system was involved in this oxidant stress. Adult Sprague-Dawley rats were treated with the xanthine oxidase inhi...

journal_title：Pediatric research

authors： Sokol RJ,Devereaux MW,Khandwala R

更新日期：1998-09-01 00:00:00

abstract：:To clarify the prevalence of Japanese children thought to be at a risk for infection with GB virus-C (GBV-C)/hepatitis G virus (HGV), we investigated the detection rates of serum GBV-C/ HGV ribonucleic acid (RNA) by reverse transcription-seminested PCR and serum anti-HGV-E2 antibody by ELISA in 162 children with histo...

journal_title：Pediatric research

authors： Goto K,Sugiyama K,Li R,Miyake Y,Ando T,Mizutani F,Terabe K,Mizuno K,Wada Y

更新日期：1999-01-01 00:00:00

abstract：:C3H/HeJ mice develop an increase in terminal air space area detectable by postnatal d 14 that persists into adulthood compared with strain-matched controls (C3H/SnJ, C3H/OuJ). Morphometric quantification revealed a 50% increase in terminal air space area by postnatal d 14 and a 2.3-fold increase by 2 mo of age in C3H/...

journal_title：Pediatric research

authors： Sampath V,Davis K,Senft AP,Richardson TR,Kitzmiller JA,Berclaz PY,Korfhagen TR

更新日期：2006-12-01 00:00:00

abstract：:Normative body composition during the first 2 y of life was derived from a prospective study of 76 children. We present 1) fat free mass (FFM) and its components, and fat mass (FM), 2) incremental growth rates partitioned into chemical components, and 3) age-specific and gender-specific constants for converting chemic...

journal_title：Pediatric research

authors： Butte NF,Hopkinson JM,Wong WW,Smith EO,Ellis KJ

更新日期：2000-05-01 00:00:00

abstract：:In view of the suggested relationship between substrate availability, fetal growth and circulating fetal IGF-I concentrations, we investigated the effect of maternal starvation on plasma IGF-I levels in the late gestation ovine fetus. Ten fetuses aged 125-130 d gestation were sampled daily from indwelling arterial cat...

journal_title：Pediatric research

authors： Bassett NS,Oliver MH,Breier BH,Gluckman PD

更新日期：1990-04-01 00:00:00

abstract：:BackgroundPatent ductus arteriosus (PDA) is a common complication seen in preterm infants. Indomethacin is routinely used to treat PDA. Evidence suggests that the response of indomethacin is highly heritable. This study investigated the association between single-nucleotide polymorphisms (SNPs) in CYP2C9 and the closu...

journal_title：Pediatric research

authors： Smith CJ,Ryckman KK,Bahr TM,Dagle JM

更新日期：2017-11-01 00:00:00

abstract：IMPACT:Raises the importance of Social Determinants of Health in pediatrics. Considers the impact of Social Determinants of Health on COVID-19. Offers opportunities for research in the future. ...

journal_title：Pediatric research

authors： Lachman P

更新日期：2020-11-10 00:00:00

abstract：:Innate immunity and urinary tract response play a central role in the development of urinary tract infection (UTI). Heat shock protein (HSP) 72 and Toll-like receptor (TLR) 4 are among the key elements of innate defence mechanisms. This study assesses the role of HSPA1B A(1267)G and TLR4 A(896)G polymorphisms using al...

journal_title：Pediatric research

authors： Karoly E,Fekete A,Banki NF,Szebeni B,Vannay A,Szabo AJ,Tulassay T,Reusz GS

更新日期：2007-03-01 00:00:00

abstract：:Five patients with Bartter's syndrome were investigated. Sodium restriction (less than 10 mEq/day for at least 5 days) showed a renal sodium wastage in only two patients (I and II) in spite of increased aldosterone secretion rate (from 151-427 to 680-842 mug/day). The effect of angiotensin II (A II) 80ng/kg/min for 30...

journal_title：Pediatric research

authors： Sann L,David M,Richard P,Floret D,Sassard J,Bizollon CA,Francois R

更新日期：1976-12-01 00:00:00

abstract：:Clinical studies have suggested that the early stages of bilirubin encephalopathy are reversible. These phenomena are investigated at the cellular level using the neuroblastoma cell line N-115 as a model system. To determine whether the cell line N-115 can recover from bilirubin toxicity, and whether the cellular func...

journal_title：Pediatric research

authors： Amit Y,Poznansky MJ,Schiff D

更新日期：1989-04-01 00:00:00

abstract：:We have previously shown that milk sensitization aggravates intestinal dysfunction in the malnourished guinea pigs, suggesting that it may also impair the recovery from malnutrition. To test this hypothesis, the growing guinea pigs were malnourished by feeding only maize for 7 d and then were refed for 21 d with a bal...

journal_title：Pediatric research

authors： Darmon N,Abdoul E,Roucayrol AM,Blaton MA,Briend A,Desjeux JF,Heyman M

更新日期：1998-12-01 00:00:00

abstract：:Children treated for acute lymphoblastic leukemia may develop reduced bone mineral density during treatment, but there is little information on the mechanisms involved. In a prospective, longitudinal study on 15 children with ALL, we undertook serial measurements of markers of bone and collagen turnover, insulin-like ...

journal_title：Pediatric research

authors： Crofton PM,Ahmed SF,Wade JC,Elmlinger MW,Ranke MB,Kelnar CJ,Wallace WH

更新日期：2000-10-01 00:00:00

abstract：:A girl presented with an important growth retardation, hepatomegaly, fasting hypoglycemia, lactic acidosis, increased serum cholesterol, triglycerides and uric acid, and increased liver glycogen (7.5%). There was no rise in blood glucose after IV galactose or fructose, but glucagon gave a delayed response. Type Ib gly...

journal_title：Pediatric research

authors： Corbeel L,Hue L,Lederer B,De Barsy T,Van den Berghe G,Devlieger H,Jaeken J,Bracke P,Eeckels R

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:The pathogenesis of BPD includes inflammation and oxidative stress in the immature lung. Corticosteroids improve respiratory status and outcome, but the optimal treatment regimen for benefit with low systemic effects is uncertain. METHODS:In a pilot dose escalation trial, we administered ≤5 daily doses of b...

journal_title：Pediatric research

authors： Ballard PL,Torgerson D,Wadhawan R,Hudak ML,Weitkamp JH,Harris J,Asselin J,Chapin C,Ballard RA,McEvoy CT

更新日期：2021-01-19 00:00:00

abstract：:Simultaneous measurements of serum immunoreactive thyrocalcitonin (iTCT), immunoreactive parathyroid hormone (iPTH), calcium, inorganic phosphate, magnesium, and alkaline phosphatase were made in 37 normal children whose ages ranged from 6-12 years. Between the ages of 6 and 12 there is a statistically significant ris...

journal_title：Pediatric research

authors： Shainkin-Kerstenbaum R,Funkenstein B,Conforti A,Shani S,Berlyne GM

更新日期：1977-02-01 00:00:00

abstract：:Neonatal group B streptococcal (GBS) sepsis produces pulmonary arterial hypertension and hypoxemia that are preventable by pretreatment with the selective thromboxane A2 synthase inhibitor, dazmegrel. In the present experiment we administered dazmegrel (8 mg/kg) 2 h after the initiation of a 2 1/2 h infusion of 5 X 10...

journal_title：Pediatric research

authors： Truog WE,Gibson RL,Juul SE,Henderson WR,Redding GJ

更新日期：1988-04-01 00:00:00