Association of attention-deficit/hyperactivity disorder with diabetes: a population-based study.

Abstract:

BACKGROUND:Cognitive impairment has been documented in adult diabetes but is unclear in pediatric diabetes. No study had been conducted to explore the relationship between attention-deficit/hyperactivity disorder (ADHD) and diabetes. Using a population-based data set, we aimed to examine the association between ADHD and a prior diagnosis of diabetes mellitus (DM) in Taiwan. METHODS:A total of 4,302 patients with ADHD were selected as cases and 21,510 randomly selected subjects as controls. We used conditional logistic regression to calculate the odds ratio (OR) for having previously received a diagnosis of DM between subjects with and without ADHD. RESULTS:In this study, 116 of the 25,812 sampled subjects (0.5%) had received a diagnosis of DM prior to their index date. Subjects with ADHD had a higher proportion of prior DM diagnoses than controls (0.9% vs. 0.4%, P < 0.001). After adjusting for age, sex, index year, geographic location, and obesity, ADHD was significantly associated with a prior diagnosis of type 2 DM (OR = 2.75, 95% confidence interval (CI) = 1.82-4.16). However, no significant association was observed between ADHD and type 1 DM. CONCLUSION:The findings suggest that ADHD was associated with a previous diagnosis of type 2 DM.

journal_name

Pediatr Res

journal_title

Pediatric research

authors

Chen HJ,Lee YJ,Yeh GC,Lin HC

doi

10.1038/pr.2013.5

subject

Has Abstract

pub_date

2013-04-01 00:00:00

pages

492-6

issue

4 Pt 1

eissn

0031-3998

issn

1530-0447

pii

pr20135

journal_volume

73

pub_type

杂志文章
  • Clinical and biochemical findings before and after portacaval shunt in a girl with type Ib glycogen storage disease.

    abstract::A girl presented with an important growth retardation, hepatomegaly, fasting hypoglycemia, lactic acidosis, increased serum cholesterol, triglycerides and uric acid, and increased liver glycogen (7.5%). There was no rise in blood glucose after IV galactose or fructose, but glucagon gave a delayed response. Type Ib gly...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-198101000-00014

    authors: Corbeel L,Hue L,Lederer B,De Barsy T,Van den Berghe G,Devlieger H,Jaeken J,Bracke P,Eeckels R

    更新日期:1981-01-01 00:00:00

  • Epidermal growth factor (EGF)-like transforming growth factor (TGF) activity and EGF receptors in ovine fetal tissues: possible role for TGF in ovine fetal development.

    abstract::To determine whether epidermal growth factor (EGF) or EGF-like transforming growth factors (TGFs) are present in ovine fetal tissues, we have tested acid-ethanol extracts of ovine fetal kidney for the ability to induce anchorage-independent growth of normal rat kidney fibroblasts in soft agar and to compete with 125I-...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-198711000-00026

    authors: Freemark M,Comer M

    更新日期:1987-11-01 00:00:00

  • IGF2 gene variants and risk of hypertension in obese children and adolescents.

    abstract::Obese children have a great risk of hypertension and cardiovascular morbidity in adults. The insulin-like growth factor type II (IGF-II) regulates glucose homeostasis, cardiovascular functions, and lipid metabolism. IGF2 gene variants have shown a strong association with weight, body mass index (BMI), and metabolic pr...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/PDR.0b013e3181d22757

    authors: Faienza MF,Santoro N,Lauciello R,Calabrò R,Giordani L,Di Salvo G,Ventura A,Delvecchio M,Perrone L,Del Giudice EM,Cavallo L

    更新日期:2010-04-01 00:00:00

  • Metabolomics of prematurity: analysis of patterns of amino acids, enzymes, and endocrine markers by categories of gestational age.

    abstract:BACKGROUND:Prematurity may influence the levels of amino acids, enzymes, and endocrine markers obtained through newborn screening. Identifying which analytes are the most affected by degree of prematurity could provide insight into how prematurity impacts metabolism. METHODS:Analytes from blood spots assayed by Newbor...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1038/pr.2013.212

    authors: Wilson K,Hawken S,Ducharme R,Potter BK,Little J,Thébaud B,Chakraborty P

    更新日期:2014-02-01 00:00:00

  • Deficient alternative complement pathway activity in newborn sera.

    abstract::Neonatal susceptibility to overwhelming bacterial infection is commonly attributed to a relative deficiency in serum opsonic activity. However, few studies have compared the functional capacity of the classical complement pathway with that of the alternative complement pathway in the neonate. The opsonic activity of n...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-197912000-00008

    authors: Mills EL,Björksteń B,Quie PG

    更新日期:1979-12-01 00:00:00

  • Response of human and rat small intestinal mucosa to oral administration of Saccharomyces boulardii.

    abstract::To evaluate the response of the small intestinal mucosa to Saccharomyces boulardii (S.b.), a yeast widely used in some countries as an adjuvant drug with oral antimicrobial therapy, seven healthy adult volunteers were treated with high doses of lyophilized S.b. (250 mg four times per day) for 2 wk. A peroral jejunal s...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-198602000-00020

    authors: Buts JP,Bernasconi P,Van Craynest MP,Maldague P,De Meyer R

    更新日期:1986-02-01 00:00:00

  • Where to make a difference: research and the social determinants in pediatrics and child health in the COVID-19 era.

    abstract:IMPACT:Raises the importance of Social Determinants of Health in pediatrics. Considers the impact of Social Determinants of Health on COVID-19. Offers opportunities for research in the future. ...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1038/s41390-020-01253-0

    authors: Lachman P

    更新日期:2020-11-10 00:00:00

  • Neutrophil recruitment by fetal porcine endothelial cells: implications in scarless fetal wound healing.

    abstract::Fetal dermal wounds heal scarlessly and with a minimal inflammatory response. When a robust inflammatory response is induced at the site of fetal dermal wounds by the application of cytokines, healing results in fibrosis. To test the hypothesis that the reduced inflammatory response in fetal wounds is due to impaired ...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/01.pdr.0000184326.01884.bc

    authors: Olutoye OO,Zhu X,Cass DL,Smith CW

    更新日期:2005-12-01 00:00:00

  • Factors influencing gastrointestinal tract and microbiota immune interaction in preterm infants.

    abstract::The role of microbial colonization is indispensable for keeping a balanced immune response in life. However, the events that regulate the establishment of the microbiota, their timing, and the way in which they interact with the host are not yet fully understood. Factors such as gestational age, mode of delivery, envi...

    journal_title:Pediatric research

    pub_type: 杂志文章,评审

    doi:10.1038/pr.2015.54

    authors: Collado MC,Cernada M,Neu J,Pérez-Martínez G,Gormaz M,Vento M

    更新日期:2015-06-01 00:00:00

  • Maternal stress during pregnancy predisposes for iron deficiency in infant monkeys impacting innate immunity.

    abstract::The influence of maternal stress during pregnancy on the postpartum iron status and immune maturation of infants was investigated in a nonhuman primate model. Forty infant rhesus monkeys were generated from two types of disturbed pregnancies, early or late gestation stress, and compared with 24 undisturbed controls. P...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/pdr.0b013e318045be53

    authors: Coe CL,Lubach GR,Shirtcliff EA

    更新日期:2007-05-01 00:00:00

  • Effect of acute polycythemia on newborn renal hemodynamics and function.

    abstract::The present study investigates the effects of polycythemia on renal hemodynamics and function in 15 anesthetized newborn dogs, 2-10 days of age. Microspheres were used to study renal blood flow. Experimental animals received an exchange transfusion with adult dog packed red blood cells resulting in an increase in hema...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-198202000-00014

    authors: Kotagal UR,Kleinman LI

    更新日期:1982-02-01 00:00:00

  • Siglec-9 and SHP-1 are differentially expressed in neonatal and adult neutrophils.

    abstract::Neonatal PMN (polymorphonuclear neutrophils) exhibit altered inflammatory responsiveness and greater longevity compared with adult PMN; however, the involved mechanisms are incompletely defined. Receptors containing immunoreceptor tyrosine-based inhibitory motif (ITIM) domains promote apoptosis by activating inhibitor...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/PDR.0b013e3181b1bc19

    authors: Rashmi R,Bode BP,Panesar N,King SB,Rudloff JR,Gartner MR,Koenig JM

    更新日期:2009-09-01 00:00:00

  • Cardiovascular autonomic regulation in preterm infants: the effect of atropine.

    abstract::To study cardiovascular autonomic control, we assessed the effect of atropine on heart rate (HR) and blood pressure (BP) variability in 12 preterm infants (range 26-32 wk) before intubation for respiratory insufficiency. Spectral power analysis of R-R interval and systolic BP (SBP) series were estimated in a low-frequ...

    journal_title:Pediatric research

    pub_type: 临床试验,杂志文章

    doi:10.1203/01.PDR.0000145257.75072.BB

    authors: Andriessen P,Janssen BJ,Berendsen RC,Oetomo SB,Wijn PF,Blanco CE

    更新日期:2004-12-01 00:00:00

  • Antenatal betamethasone alters vascular reactivity in adult female ovine cerebral arteries.

    abstract::Although the use of antenatal glucocorticoids has resulted in decreased neonatal morbidity/mortality, recent animal studies have raised concerns regarding adverse effects of these medications on postnatal cardiovascular function. We hypothesized that antenatal betamethasone (Beta) exposure alters cerebral vascular rea...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/PDR.0b013e3181edb9fa

    authors: Eckman DM,Kerr BA,Fuloria M,Simandle SA,Watt SE,Rose JC,Figueroa JP

    更新日期:2010-10-01 00:00:00

  • The life span of erythrocytes transfused to preterm infants.

    abstract::This study was made to determine the life span of adult red cells transfused to early preterm infants. Nineteen very preterm infants (birth weight, 878.7 +/- 221 g; gestational age, 26.8 +/- 1.5 wk at birth) were sampled weekly after their last blood transfusion to determine the level (%) of fetal Hb in their circulat...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-199707000-00002

    authors: Bard H,Widness JA

    更新日期:1997-07-01 00:00:00

  • Glucose metabolism of human mononuclear cell subpopulations.

    abstract::Previous studies have demonstrated metabolic dysfunction in the mononuclear cells of some children with abnormal cell-mediated immunity. Interpretation of these observations has been complicated by the extreme heterogeneity of cell types examined. The glycolytic metabolism of relatively enriched T-cells, non-T mononuc...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-198002000-00005

    authors: Storch S,Klein W,Feig SA,Henderson T

    更新日期:1980-02-01 00:00:00

  • Physical properties of bedding that may increase risk of sudden infant death syndrome in prone-sleeping infants.

    abstract::Soft bedding has been shown in epidemiologic studies to increase the risk for sudden, unexpected death in prone-sleeping infants. We compared the physical properties of conventional bedding to bedding from two sources: 1) bedding that covered the airways of victims of sudden infant death syndrome (SIDS) lying prone an...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-199407001-00002

    authors: Kemp JS,Nelson VE,Thach BT

    更新日期:1994-07-01 00:00:00

  • Role of endogenous atrial natriuretic peptide in chronic anemia in the ovine fetus: effects of a non-peptide antagonist for atrial natriuretic peptide receptor.

    abstract::Chronic fetal anemia causes polyhydramnios and fetal hydrops and is associated with increased fetal diuresis and natriuresis. To determine the role of atrial natriuretic peptide (ANP) in the renal adaptation to chronic fetal anemia we studied the effects of HS-142-1 (HS), a specific inhibitor of the guanylate cyclase-...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-199511000-00015

    authors: Silberbach M,Woods LL,Hohimer AR,Shiota T,Matsuda Y,Davis LE

    更新日期:1995-11-01 00:00:00

  • Serial assessment of fat and fat-free mass accretion in very preterm infants: a randomized trial.

    abstract:BACKGROUND:Clinicians could modify dietary interventions during early infancy by monitoring fat and fat-free mass accretion in very preterm infants. METHODS:Preterm infants were randomly assigned to either having reports on infant body composition available to the clinicians caring for them (intervention group) or not...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1038/s41390-020-1052-x

    authors: Salas AA,Jerome ML,Chandler-Laney P,Ambalavanan N,Carlo WA

    更新日期:2020-11-01 00:00:00

  • Longitudinal cognitive development of children born to mothers with opioid and polysubstance use.

    abstract:BACKGROUND:Previous studies indicate an increased risk for neuropsychological difficulties in young children prenatally exposed to opioids and polysubstances, but longitudinal information is scarce. The present longitudinal study investigated whether these waned, persisted, or increased over time. METHODS:The cognitiv...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1038/pr.2015.95

    authors: Nygaard E,Moe V,Slinning K,Walhovd KB

    更新日期:2015-09-01 00:00:00

  • A novel missense mutation in the transcription factor FOXF1 cosegregating with infantile hypertrophic pyloric stenosis in the extended pedigree linked to IHPS5 on chromosome 16q24.

    abstract:BACKGROUND:The aim was to identify susceptibility alleles for infantile hypertrophic pyloric stenosis (IHPS) in a pedigree previously linked to IHPS5 on chromosome 16q24. METHODS:We screened the positional and functional candidate gene FOXF1 by Sanger sequencing in a single affected individual. All family members for ...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1038/pr.2016.244

    authors: Everett KV,Ataliotis P,Chioza BA,Shaw-Smith C,Chung EMK

    更新日期:2017-04-01 00:00:00

  • Ischemia-reperfusion injury in the intestines of newborn pigs.

    abstract::Although the pathogenesis of necrotizing enterocolitis remains uncertain, ischemia appears to be an important contributing factor to the development of this disorder. Reperfusion plays a major role in ischemia-related injury, and oxygen free radicals produced during reperfusion most likely contribute to the injury. Th...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-199708000-00009

    authors: Papparella A,DeLuca FG,Oyer CE,Pinar H,Stonestreet BS

    更新日期:1997-08-01 00:00:00

  • Molecular and genetic analyses of two patients with Pearson's marrow-pancreas syndrome.

    abstract::Pearson's syndrome, a rare and fatal disorder characterized by refractory sideroblastic anemia and pancreatic insufficiency in infancy, is classified into mitochondrial cytopathies. To understand the molecular and genetic bases of this disorder, we have investigated the mitochondrial respiratory chain enzymes and the ...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-199307000-00024

    authors: Sano T,Ban K,Ichiki T,Kobayashi M,Tanaka M,Ohno K,Ozawa T

    更新日期:1993-07-01 00:00:00

  • Effect of alpha-phenyl-N-tert-butyl nitrone (PBN) on fetal cerebral energy metabolism during intrauterine ischemia and reperfusion in rats.

    abstract::The objective of the present study was to explore whether a free radical spin trap agent, alpha-phenyl-N-tert-butyl nitrone (PBN), influences bioenergetic failure induced in the 20-day-old fetal brain by 30 min of intrauterine ischemia in Wistar rats. Fetal brains were frozen in situ at the end of ischemia and after 1...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-200004000-00007

    authors: Nakai A,Asakura H,Taniuchi Y,Koshino T,Araki T,Siesjö BK

    更新日期:2000-04-01 00:00:00

  • Medium chain acyl-CoA dehydrogenase deficiency in Pennsylvania: neonatal screening shows high incidence and unexpected mutation frequencies.

    abstract::Medium chain acyl-CoA dehydrogenase deficiency (MCAD) is a defect in the mitochondrial oxidation of fatty acids. The disorder typically presents with episodes of vomiting and hypoglycemia, sometimes with changes in mental status and hepatic failure. These Reye's-like features may culminate in coma and death. Stress, i...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-199505000-00021

    authors: Ziadeh R,Hoffman EP,Finegold DN,Hoop RC,Brackett JC,Strauss AW,Naylor EW

    更新日期:1995-05-01 00:00:00

  • Epileptogenesis is increased in rats with neonatal isolation and early-life seizure and ameliorated by MK-801: a long-term MRI and histological study.

    abstract::Early-life stress has been shown to destabilize the homeostatic synaptic plasticity and compromise the developing brain to the later encountered insults. This study would determine the long-term epileptogenic effect of neonatal isolation (NI) on early-life seizure. There were five groups: normal rearing (NR) rats; NI ...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/PDR.0b013e3181b337d2

    authors: Lai MC,Lui CC,Yang SN,Wang JY,Huang LT

    更新日期:2009-10-01 00:00:00

  • A statistical comparison of reproducibility in current pediatric two-dimensional echocardiographic nomograms.

    abstract:BACKGROUND:The aim of this study is to compare new pediatric nomograms for clinical parameters from 2D echocardiography. METHODS:2D pediatric echocardiographic parameters from four recent nomograms were used for statistical analysis. To assess the accuracy of the predictive models from each study, namely multivariate,...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1038/s41390-020-0900-z

    authors: Cantinotti M,Scalese M,Giordano R,Assanta N,Marchese P,Franchi E,Viacava C,Koestenberger M,Jani V,Kutty S

    更新日期:2020-04-24 00:00:00

  • MR imaging correlates of white-matter pathology in a preterm baboon model.

    abstract:INTRODUCTION:Cerebral white-matter (WM) abnormalities on magnetic resonance imaging (MRI) correlate with neurodevelopmental disability in infants born prematurely. RESULTS:Quantitative histological measures of WM and ventricular volumes correlated with qualitative MRI scores of WM volume loss and ventriculomegaly. Dif...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1038/pr.2011.33

    authors: Griffith JL,Shimony JS,Cousins SA,Rees SE,McCurnin DC,Inder TE,Neil JJ

    更新日期:2012-02-01 00:00:00

  • Impact of norepinephrine and fluid on cerebral oxygenation in experimental hemorrhagic shock.

    abstract::Few data exist regarding resuscitation of hypovolemic shock in infants, and alternative strategies such as vasopressor therapy merit further evaluation. However, the effects of norepinephrine on cerebral perfusion and oxygenation during hemorrhagic shock in the pediatric population are still unclear. Eight anesthetize...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/PDR.0b013e3181425858

    authors: Meybohm P,Renner J,Boening A,Cavus E,Gräsner JT,Grünewald M,Scholz J,Bein B

    更新日期:2007-10-01 00:00:00

  • Effects of dietary fish oil on intestinal adaptation in 20-day-old weanling rats after massive ileocecal resection.

    abstract::Long chain polyunsaturated fatty acids (LCPUFA)seem to be the most trophic macronutrients in inducing intestinal adaptation in adult short bowel syndrome (SBS), although their effects on intestinal adaptation in infants with SBS remain unknown.It is hypothesized that a high fat diet enriched with n-3 LCPUFA derived fr...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/PDR.0b013e3181eb2ee5

    authors: Yang Q,Kock ND

    更新日期:2010-09-01 00:00:00