Glucose metabolism of human mononuclear cell subpopulations.

abstract：:A sensitive and rapid high-performance liquid chromatography method for determining lecithin/sphingomyelin (L/S) ratios in small volume tracheal aspirates has been evaluated in 115 infants sampled within 3 h of delivery. Respiratory distress syndrome was present in 41 infants and all had L/S ratios of less than or equ...

journal_title：Pediatric research

authors： D'Costa M,Dassin R,Bryan H

更新日期：1987-08-01 00:00:00

abstract：:Immunologic consequences of exposure to HIV-1 in utero are still poorly understood. This study investigates relationships between type-1 [interferon-gamma (IFN-gamma)] and type-2 (IL-10) cytokine production and maternal-infant HIV-1 transmission. Cord blood leukocytes from deliveries of 71 HIV-1-infected and 11 uninfe...

journal_title：Pediatric research

authors： Kuhn L,Coutsoudis A,Moodley D,Mngqundaniso N,Trabattoni D,Shearer GM,Clerici M,Coovadia HM

更新日期：2001-09-01 00:00:00

abstract：:Maternal smoking doubles the risk of delivering a low birth weight infant. The purpose of this study was to analyze differential gene expression in umbilical cord tissue as a function of maternal smoking, with an emphasis on growth-related genes. We recruited 15 pregnant smokers and 15 women who never smoked during pr...

journal_title：Pediatric research

authors： Hussain N,Krueger W,Covault J,Walsh S,Kranzler HR,Oncken C

更新日期：2008-08-01 00:00:00

abstract：:Late Onset Central Hypoventilation Syndrome associated with Hypothalamic Dysfunction (LO-CHS/HD) is a distinct entity among the clinical and genetic heterogeneous group of patients with late onset central hypoventilation. Here we report a series of 13 patients with LO-CHS/HD. Rapid onset obesity is the first symptom o...

journal_title：Pediatric research

authors： De Pontual L,Trochet D,Caillat-Zucman S,Abou Shenab OA,Bougneres P,Crow Y,Cunningham S,Esteva B,Heberle LC,Leger J,Pinto G,Polak M,Shafik MH,Straus C,Trang H,Munnich A,Lyonnet S,Desguerre I,Amiel J

更新日期：2008-12-01 00:00:00

abstract：:Normal values for the percentages of lymphocytes carrying surface membrane-bound immunoglobulin, or rosetting with sheep erythrocytes, ox erythrocytes coated with rabbit immunoglobulin G, or ox erythrocytes coated with rabbit immunoglobulin M and reacted with human serum partially de-complemented with zymozan, have be...

journal_title：Pediatric research

authors： Stern CM

更新日期：1979-06-01 00:00:00

abstract：:Early childhood overweight and obesity have alarmingly increased over the years. Adulthood obesity is a well demonstrated significant independent predictor of cardiovascular risk (CVR) and/or mortality, which predisposes to the major components of metabolic syndrome (MS). Evidence of MS in obese children has been also...

journal_title：Pediatric research

authors： Aggoun Y

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:To minimize secondary lung injury, ventilated preterm infants are extubated as soon as possible. To maximize extubation success, they are often placed in prone position. The effect of extubation and subsequent prone positioning on lung volumes is currently unknown. METHODS:Changes in end-expiratory lung vol...

journal_title：Pediatric research

authors： van der Burg PS,Miedema M,de Jongh FH,Frerichs I,van Kaam AH

更新日期：2015-03-01 00:00:00

abstract：:In seven patients with mucopolysaccharidoses (1 Hurler, 1 Hurler-Scheie, 4 Hunter, 1 Sly), cranial (1)H-magnetic resonance spectroscopy was performed to evaluate the accumulation of mucopolysaccharides and biochemical changes in the CNS in vivo before and after bone marrow transplantation (BMT). In two of seven patien...

journal_title：Pediatric research

authors： Takahashi Y,Sukegawa K,Aoki M,Ito A,Suzuki K,Sakaguchi H,Watanabe M,Isogai K,Mizuno S,Hoshi H,Kuwata K,Tomatsu S,Kato S,Ito T,Kondo N,Orii T

更新日期：2001-03-01 00:00:00

abstract：:Diarrheal disease is a worldwide problem that still causes significant morbidity and mortality among children. Currently, oral rehydration solution (ORS) is the standard of care for acute diarrhea in pediatric patients. Although effective in reducing mortality, ORS does not alleviate diarrheal symptoms, thus reducing ...

journal_title：Pediatric research

authors： Harrell JE,Cheng SX

更新日期：2018-03-01 00:00:00

abstract：:Treatment with phototherapy or with the lipase inhibitor orlistat decreases plasma unconjugated bilirubin (UCB) concentrations in hyperbilirubinemic Gunn rats. We investigated the mechanism(s) underlying the effects of orlistat, phototherapy, and combined treatment, using steady-state 3H-UCB kinetics. After three week...

journal_title：Pediatric research

authors： Hafkamp AM,Havinga R,Ostrow JD,Tiribelli C,Pascolo L,Sinaasappel M,Verkade HJ

更新日期：2006-04-01 00:00:00

abstract：:We investigated the early postnatal changes of the mesenteric circulation and its relation to the systemic circulation in 15 preterm infants. The infants were studied before the first feeding on d 1 and pre- and postprandially on d 3, 4, 5, and 7. Blood flow velocity was measured by ultrasound Doppler in the superior ...

journal_title：Pediatric research

authors： Martinussen M,Brubakk AM,Vik T,Yao AC

更新日期：1996-02-01 00:00:00

abstract：:Platelet volume was measured in 20 healthy children, 18 patients with acute idiopathic thrombocytopenic purpura (ITP), 24 patients with chronic ITP, 22 patients with aplastic anemia, and 17 patients with acute leukemia in childhood. The authors compared the platelet volume of these patients by use of peak platelet vol...

journal_title：Pediatric research

authors： Tomita E,Akatsuka JI,Kokubun Y

更新日期：1980-02-01 00:00:00

abstract：:We investigated, using a human placental choriocarcinoma cell line as a model, the effects of the immunosuppressive drug cyclosporin A on several placental transport systems mediating the transfer of glucose and amino acids from mother to fetus. The results of the investigation show that the transport system responsib...

journal_title：Pediatric research

authors： Ramamoorthy S,Leibach FH,Mahesh VB,Ganapathy V

更新日期：1992-07-01 00:00:00

abstract：INTRODUCTION:The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) serves 50% of infants and 25% of preschool-aged children in the United States and collects height and weight measurements from eligible children every 6 mo, making WIC data a valuable resource for studying childhood growth an...

journal_title：Pediatric research

authors： Crespi CM,Alfonso VH,Whaley SE,Wang MC

更新日期：2012-03-01 00:00:00

abstract：:Diabetes mellitus is characterized by microangiopathy and increased angiogenic response in various organs. Basic fibroblast growth factor (bFGF) as well as vascular endothelial growth factor (VEGF) are both angiogenic and are involved in vascular endothelial cell growth. The purpose of this study was to determine seru...

journal_title：Pediatric research

authors： Malamitsi-Puchner A,Sarandakou A,Tziotis J,Dafogianni C,Bartsocas CS

更新日期：1998-12-01 00:00:00

abstract：:Automated microanalytic chromogenic coagulation assays allow serial monitoring of critically ill newborn infants. In this study 84 premature infants [26 healthy prematures and 58 neonates with idiopathic respiratory distress syndrome (IRDS)] were studied daily during the first week of life, to investigate the possible...

journal_title：Pediatric research

authors： Peters M,Ten Cate JW,Breederveld C,De Leeuw R,Emeis J,Koppe J

更新日期：1984-03-01 00:00:00

abstract：:Premature infants are at risk for bilirubin-associated brain damage. In cell cultures bilirubin causes neuronal apoptosis and necrosis. Ibuprofen is used to close the ductus arteriosus, and is often given when hyperbilirubinemia is at its maximum. Ibuprofen is known to interfere with bilirubin-albumin binding. We hypo...

journal_title：Pediatric research

authors： Berns M,Toennessen M,Koehne P,Altmann R,Obladen M

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The basal ganglia are vulnerable to injury during cardiac arrest. Movement disorders are a common morbidity in survivors. Yet, neuronal motor network changes post-arrest remain poorly understood. METHODS:We compared function of the motor network in adult rats that, during postnatal week 3, underwent 9.5 min...

journal_title：Pediatric research

authors： Aravamuthan BR,Shoykhet M

更新日期：2015-10-01 00:00:00

abstract：:In blood vessels with diameters less than 500 microns, both the hematocrit and viscosity decrease with decreasing tube diameter [Fåhraeus effect (FE) and Fåhraeus-Lindqvist effect (FLE)]. Because both effects may be influenced by red blood cell (RBC) volume and osmolality, the effects of RBC type and suspending medium...

journal_title：Pediatric research

authors： McKay CB,Linderkamp O,Meiselman HJ

更新日期：1993-10-01 00:00:00

abstract：:Unconjugated bilirubin promotes intestinal secretion without affecting nutrient digestion or absorption. In the current study, the effects of unconjugated bilirubin (UCB) on the barrier function of the intestinal epithelium were investigated. The apical side of human intestinal cell line Caco-2 monolayers was challeng...

journal_title：Pediatric research

authors： Raimondi F,Crivaro V,Capasso L,Maiuri L,Santoro P,Tucci M,Barone MV,Pappacoda S,Paludetto R

更新日期：2006-07-01 00:00:00

abstract：:The incidence of allergic diseases has increased, and a relation between allergy and dietary fatty acids has been proposed. Modulation of the maternal immune function during pregnancy may have an impact on future clinical outcomes in the child. The aim of this study was to determine the effects of omega (omega)-3 long...

journal_title：Pediatric research

authors： Warstedt K,Furuhjelm C,Duchén K,Fälth-Magnusson K,Fagerås M

更新日期：2009-08-01 00:00:00

abstract：:Hyperprostaglandin E syndrome (HPS), the prenatal variant of Bartter's syndrome, is characterized by a marked and selective stimulation of prostaglandin E (PGE2) synthesis. In the study group HPS patients showed increased urinary levels of PGE2, an index of renal, and of 11 alpha-hydroxy-9,15-dioxo-2,3,4,5,20-pentanor...

journal_title：Pediatric research

authors： Nüsing RM,Schaub TP,Klein T,Schweer H,Seyberth HW

更新日期：1997-08-01 00:00:00

abstract：:We investigated the developmental changes in the pattern of urinary metabolites of theophylline, a substrate for CYP1A2, to study when CYP1A2, which is absent in the perinatal period, fully develops during childhood. The urinary ratios of three metabolites (1-methyluric acid, 3-methylxanthine, and 1,3-dimethyluric aci...

journal_title：Pediatric research

authors： Tateishi T,Asoh M,Yamaguchi A,Yoda T,Okano YJ,Koitabashi Y,Kobayashi S

更新日期：1999-01-01 00:00:00

abstract：:We have previously demonstrated that enterally administered heparin-binding EGF-like growth factor (HB-EGF) produced in Escherichia coli decreases the incidence and severity of intestinal injury in a neonatal rat model of necrotizing enterocolitis (NEC). In preparation for upcoming human clinical trials, large-scale p...

journal_title：Pediatric research

authors： Radulescu A,Zorko NA,Yu X,Besner GE

更新日期：2009-04-01 00:00:00

abstract：:Hypoxia and other adverse conditions are commonly encountered by rapidly growing cells. The RNA-binding protein RBM3 (RNA-binding motif protein 3), which is transcriptionally induced by low temperature and hypoxia, has recently been implicated in survival of colon cancer cells by mechanisms involving cyclooxygenase-2 ...

journal_title：Pediatric research

authors： Wellmann S,Truss M,Bruder E,Tornillo L,Zelmer A,Seeger K,Bührer C

更新日期：2010-01-01 00:00:00

abstract：:Lung development requires extracellular matrix remodeling. This involves matrix metalloproteinases (MMPs) and their endogenous inhibitors [tissue inhibitors of metalloproteinases (TIMPs)]. Because these have been generally studied only in whole lung, we focused specifically on mesenchymal and epithelial cells freshly ...

journal_title：Pediatric research

authors： Boucherat O,Bourbon JR,Barlier-Mur AM,Chailley-Heu B,D'Ortho MP,Delacourt C

更新日期：2007-07-01 00:00:00

abstract：:Branching morphogenesis, defined as growth and branching of epithelial tubules during embryogenesis, is a fundamental feature of renal, lung, mammary gland, submandibular gland, and pancreatic morphogenesis in mammals. Disruption of branching morphogenesis has been demonstrated to result in maldevelopment of some of t...

journal_title：Pediatric research

authors： Hu MC,Rosenblum ND

更新日期：2003-10-01 00:00:00

abstract：:Tolazoline is used in neonatal intensive care to treat hypoxia secondary to persistent pulmonary hypertension of the newborn. Its use is often complicated by systemic hypotension. We compared the effect of tolazoline-induced hypotension on organ blood flow, regional brain blood flow, and cerebral metabolism in hypoxic...

journal_title：Pediatric research

authors： Balsan MJ,Cronin CM,Shaw MD,Milley JR

更新日期：1990-08-01 00:00:00

abstract：:This investigation was undertaken to determine the nature of acute alterations in renal function following the production of hypoxemia, hypercarbia, and acidosis in newborn piglets 6-96 hr of age. After completion of the surgical procedure piglets were allowed to recover from the effects of anesthesia. When respirator...

journal_title：Pediatric research

authors： Alward CT,Hook JB,Helmbrath TA,Bailie MD

更新日期：1978-03-01 00:00:00

abstract：:Docosahexaenoic acid (DHA), a 22-carbon, highly unsaturated, n-3 fatty acid, is important for optimal nervous system function. In this study, designed to quantify how preformed dietary DHA regulates metabolic pathways in vivo, 8-d-old rat pups were divided into four groups and fed artificial rat milk diets. One group ...

journal_title：Pediatric research

authors： Lefkowitz W,Lim SY,Lin Y,Salem N Jr

更新日期：2005-01-01 00:00:00