Abstract:
BACKGROUND:The aim of this study is to compare new pediatric nomograms for clinical parameters from 2D echocardiography. METHODS:2D pediatric echocardiographic parameters from four recent nomograms were used for statistical analysis. To assess the accuracy of the predictive models from each study, namely multivariate, linear, and nonlinear regression, mean values and 5th and 95th percentiles (μ ± 1.65σ) were calculated. A Z-score calculator was created. RESULTS:Mean values and 5th and 95th percentiles have been provided for a range of BSA (0.15-2.20 m2) for each nomogram assessed in this study. Moreover, plots of Z-scores over the same range of BSA have been generated to assess trends among different studies. For most measurements from the two most recent nomograms, namely Lopez et al. and Cantinotti et al., differences were within a Z-score of 0.5 (Z-score range: 0.001-1.26). Measurements from Sluysmans and Colan and Pettersen et al. were observed to diverge from Lopez et al. at the upper extremities of BSA. Differences among various nomograms emerged at lower extremes of BSA. CONCLUSIONS:The two most recent echocardiographic nomograms were observed to have the most statistically similar ranges of normality. Significant deviations in ranges of normality were observed at extremes of BSA. IMPACT:Echocardiographic nomograms for pediatric age are discordant.Comparison of current pediatric echocardiographic nomograms.A Z-score calculator was created.Clinical relevance of differences among nomograms is highlighted.
journal_name
Pediatr Resjournal_title
Pediatric researchauthors
Cantinotti M,Scalese M,Giordano R,Assanta N,Marchese P,Franchi E,Viacava C,Koestenberger M,Jani V,Kutty Sdoi
10.1038/s41390-020-0900-zsubject
Has Abstractpub_date
2020-04-24 00:00:00eissn
0031-3998issn
1530-0447pii
10.1038/s41390-020-0900-zpub_type
杂志文章abstract::A series of in vivo experiments is described in which [1-13C]phytanic acid was given as an oral substrate to a healthy subject and two patients showing an impairment in phytanic acid degradation, one with Refsum's disease and one with chondrodysplasia punctata. After intake of the substrate by the control in a dose of...
journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1203/00006450-199211000-00016
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journal_title:Pediatric research
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更新日期:1987-05-01 00:00:00
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journal_title:Pediatric research
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pub_type: 杂志文章
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更新日期:2020-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1203/00006450-199005000-00021
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abstract::A specific, enzyme-linked immunoabsorbent assay was used to determine the concentration of the 35,000 mol wt surfactant apoprotein (SP-A) in samples of amniotic fluid obtained from nondiabetic (n = 358) and diabetic (n = 29) women. The enzyme-linked immunoabsorbent assay was performed with rabbit antibodies directed a...
journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1203/00006450-198812000-00016
更新日期:1988-12-01 00:00:00
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更新日期:2003-08-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2013-08-01 00:00:00
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更新日期:2010-10-01 00:00:00
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更新日期:1991-06-01 00:00:00
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更新日期:1997-09-01 00:00:00
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更新日期:1996-07-01 00:00:00
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更新日期:2006-04-01 00:00:00
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