The life span of erythrocytes transfused to preterm infants.

abstract：BACKGROUND:Adult human airway smooth muscle (ASM) produce cytokines involved in recruitment and survival of leukocytes within airway walls. Cytokine generation by adult ASM is glucocorticoid-sensitive. Whether developing lung ASM produces cytokines in a glucocorticoid-sensitive fashion is unknown. METHODS:Cultured fet...

journal_title：Pediatric research

authors： Pearson H,Britt RD Jr,Pabelick CM,Prakash YS,Amrani Y,Pandya HC

更新日期：2015-12-01 00:00:00

abstract：:Pups delivered by rats fed during pregnancy a choline-deficient (CD) diet containing 1% N,N-dimethylaminoethanol (DME) die within 36 hr of birth. The concentrations of sphingomyelins, phosphatidyl cholines, and disaturated phosphatidyl cholines in the lungs of these pups are lower than those in the lungs of pups deliv...

journal_title：Pediatric research

authors： Katyal SL,Lombardi B

更新日期：1978-09-01 00:00:00

abstract：:Extracellular glutathione peroxidase (E-GPx) is a selenoenzyme that reduces hydrogen peroxide and organic peroxides. All plasma glutathione peroxidase (GPx) activity in humans is attributable to E-GPx. The gastrointestinal (GI) tract also synthesizes and secretes E-GPx into the extracellular milieu. Endogenously gener...

journal_title：Pediatric research

authors： Tham DM,Whitin JC,Cohen HJ

更新日期：2002-05-01 00:00:00

abstract：:It is increasingly recognized that the abnormal physiologic consequences of pulmonary hypertension (PH) may contribute to poor cardiopulmonary health in premature babies. Conflicting literature has led to clinical uncertainty, pathological misinterpretation, and variability in treatment approaches among practitioners....

journal_title：Pediatric research

authors： Giesinger RE,More K,Odame J,Jain A,Jankov RP,McNamara PJ

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Prolonged hypoglycemia leads to brain injury, despite treatment with 10% dextrose. Whether induction of hyperglycemia or ketonemia achieves better neuroprotection is unknown. Hyperglycemia is neuroprotective in other brain injuries during development; however, it worsens hypoglycemia-induced injury in the ad...

journal_title：Pediatric research

authors： Ennis K,Dotterman H,Stein A,Rao R

更新日期：2015-01-01 00:00:00

abstract：:There is in vitro evidence that the ductus venosus of the fetal and newborn lamb relaxes to administration of E-series prostaglandins. We performed this study to determine whether the ductus venosus of the newborn lamb could be reopened by an infusion of prostaglandin E1. Fifteen lambs between 4 and 28 h of life and s...

journal_title：Pediatric research

authors： Morin FC 3rd

更新日期：1987-03-01 00:00:00

abstract：:Cerebral blood flow (CBF) was measured by means of Celabeled microspheres in infant (20-day-old) and adult (3-month-old) rats, anesthetised with Na-5-ethyl-5-(1-methylpropyl)2-thiobarbituric acid. Cerebral arteriovenous differences of acetoacetate, D-beta-hydroxybutyrate, glucose, lactate, and oxygen and brain DNA con...

journal_title：Pediatric research

authors： Dahlquist G,Persson B

更新日期：1976-11-01 00:00:00

abstract：:Respiratory distress syndrome (RDS) due to surfactant deficiency is the most common cause of respiratory failure in preterm infants. Tremendous progress has been made since the original description that surfactant deficiency is the major cause of RDS. Surfactant therapy has been extensively studied in preterm infants ...

journal_title：Pediatric research

authors： Sardesai S,Biniwale M,Wertheimer F,Garingo A,Ramanathan R

更新日期：2017-01-01 00:00:00

abstract：:Injuries continue to be the leading cause of morbidity and mortality for children, adolescents, and young adults aged 1-24 years in industrialized countries in the twenty-first century. In this age group, injuries cause more fatalities than all other causes combined in the United States (U.S.). Importantly, many of th...

journal_title：Pediatric research

authors： Dorney K,Dodington JM,Rees CA,Farrell CA,Hanson HR,Lyons TW,Lee LK,and the Injury Free Coalition for Kids®.

更新日期：2020-01-01 00:00:00

abstract：:We assessed auditory event-related potentials in small-for-gestational-age (SGA; 850 +/- 258 g, 28.9 +/- 3.3 gestational wk; n = 15) and appropriate for gestational age (AGA; 1014 +/- 231 g, 26.9 +/- 1.9 gestational wk; n = 20) preterm infants and healthy term infants (n = 22). An oddball paradigm was used with a harm...

journal_title：Pediatric research

authors： Fellman V,Kushnerenko E,Mikkola K,Ceponiene R,Leipala J,Naatanen R

更新日期：2004-08-01 00:00:00

abstract：:Spring steel coils have been used to occlude abnormal vessels in patients with a congenital heart malformation. However, long-term adverse effects of steel spring coils remain uncertain, although some long-term results appear to be good. The purpose of this study was to evaluate the angiographic and histologic results...

journal_title：Pediatric research

authors： Ino T,Kishiro M,Yamashiro Y,Tanaka A,Ito H

更新日期：1998-04-01 00:00:00

abstract：:Long-term EEG monitoring (LTM) with several electrodes could be a useful tool for surveillance of the brain during the first critical days of life. This study aimed to assess the feasibility of multichannel LTM for automated analysis of EEG activity from d 1 to 3 using eight electrodes. Premature infants (GA <31 wk; n...

journal_title：Pediatric research

authors： Schumacher EM,Westvik AS,Larsson PG,Lindemann R,Westvik J,Stiris TA

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Near-infrared spectroscopy is used in the assessment of regional splanchnic oxygen saturation (rsSO2), but solid reference values are scarce. We aimed to establish reference values of rsSO2 for preterm infants during the first week after birth, both crude and modeled based on predictors. METHODS:We included...

journal_title：Pediatric research

authors： van der Heide M,Dotinga BM,Stewart RE,Kalteren WS,Hulscher JBF,Reijneveld SA,Bos AF,Kooi EMW

更新日期：2021-01-27 00:00:00

abstract：:Studies in adult animal and human subjects have suggested that the methylxanthine drugs can delay the onset or attenuate the severity of diaphragmatic fatigue. We have investigated the effect of aminophylline and caffeine on the pressure-generating capacity of the fatigued diaphragm in 1-mo-old piglets. Measurements o...

journal_title：Pediatric research

authors： Mayock DE,Standaert TA,Woodrum DE

更新日期：1992-11-01 00:00:00

abstract：:Tolazoline is used in neonatal intensive care to treat hypoxia secondary to persistent pulmonary hypertension of the newborn. Its use is often complicated by systemic hypotension. We compared the effect of tolazoline-induced hypotension on organ blood flow, regional brain blood flow, and cerebral metabolism in hypoxic...

journal_title：Pediatric research

authors： Balsan MJ,Cronin CM,Shaw MD,Milley JR

更新日期：1990-08-01 00:00:00

abstract：:Very young children with organic brain damage, intractable seizures, and developmental retardation are at particular risk of developing fatal hepatic dysfunction coincident with valproate therapy, especially if the children are also receiving other anticonvulsant drugs. The mechanism of valproate-associated hepatic fa...

journal_title：Pediatric research

authors： Thurston JH,Hauhart RE

更新日期：1992-04-01 00:00:00

abstract：:All-trans retinoic acid (ATRA) stimulates platelet-derived growth factor (PDGF)-A expression and enhances alveolarization in rat lungs. On d 16 of gestation, pregnant Sprague-Dawley rats were randomly assigned to either a retinoic acid group (intragastric ATRA at 10 mg/kg body weight) or a vehicle group. We punctured ...

journal_title：Pediatric research

authors： Chen CM,Chou HC,Wang LF,Lang YD,Yeh CY

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Intrauterine inflammation adversely affects cardiopulmonary, systemic, and cerebral hemodynamics in preterm neonates, but its impact on responses to endotracheal tube (ETT) suction, known to affect hemodynamics, is unknown. We hypothesized that intrauterine inflammation would alter the cardiopulmonary and ce...

journal_title：Pediatric research

authors： Galinsky R,Moss TJ,Polglase GR,Hooper SB

更新日期：2013-07-01 00:00:00

abstract：:Ethylmalonic aciduria is a common biochemical finding in patients with inborn errors of short chain fatty acid beta-oxidation. The urinary excretion of ethylmalonic acid (EMA) may stem from decreased oxidation by short chain acyl-CoA dehydrogenase (SCAD) of butyryl-CoA, which is alternatively metabolized by propionyl-...

journal_title：Pediatric research

authors： Corydon MJ,Gregersen N,Lehnert W,Ribes A,Rinaldo P,Kmoch S,Christensen E,Kristensen TJ,Andresen BS,Bross P,Winter V,Martinez G,Neve S,Jensen TG,Bolund L,Kølvraa S

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:The associations between prenatal exposure to endocrine disruptive chemicals (EDCs) and fetal growth are inconsistent, and few studies have considered small-for-gestational-age (SGA) birth as an outcome. Our current study of Scandinavian parous women aimed to address these inconsistencies and gaps in the lit...

journal_title：Pediatric research

authors： Lauritzen HB,Larose TL,Øien T,Sandanger TM,Odland JØ,van de Bor M,Jacobsen GW

更新日期：2017-01-01 00:00:00

abstract：:The auditory brainstem response (ABR) was monitored in nine infant rhesus monkeys during the intravenous infusion of 50-168 mg/kg of unconjugated bilirubin. Sulfisoxazole (200 mg/kg) was sometimes given near the end of or just before the bilirubin infusion if no obvious ABR change had yet occurred. Five of the animals...

journal_title：Pediatric research

authors： Ahlfors CE,Bennett SH,Shoemaker CT,Ellis WG,Davis SL,Wennberg RP,Goetzman BW

更新日期：1986-06-01 00:00:00

abstract：:The prevalence of iron deficiency was determined in Göteborg, Sweden, in a sample of 15- to 16-y-old girls (n = 220) and boys (n = 207) using serum ferritin (SF). In a recent study in women on the relationship between SF and stainable bone marrow iron, it was established that at a cutoff value for SF of < 16 microgram...

journal_title：Pediatric research

authors： Hallberg L,Hultén L,Lindstedt G,Lundberg PA,Mark A,Purens J,Svanberg B,Swolin B

更新日期：1993-11-01 00:00:00

abstract：:Phagocytosis of apoptotic cells, e.g., neutrophils, by monocytes is essential for resolution of inflammation. Delayed removal leads to secondary necrosis, perpetuating inflammation, and tissue destruction. Common histologic features in neonatal chronic inflammatory disorders are an accumulation of apoptotic cells in i...

journal_title：Pediatric research

authors： Gille C,Steffen F,Lauber K,Keppeler H,Leiber A,Spring B,Poets CF,Orlikowsky TW

更新日期：2009-11-01 00:00:00

abstract：:Monocyte chemoattractant protein-1 (MCP-1), acting through its C-C chemokine receptor 2 (CCR-2), has important roles in inflammation, angiogenesis, and wound repair. The individual and combined effects of inhaled nitric oxide (NO) and hyperoxia on lung MCP-1 and CCR-2 in relation to lung leukocyte dynamics are unknown...

journal_title：Pediatric research

authors： Ekekezie II,Thibeault DW,Garola RE,Truog WE

更新日期：2001-11-01 00:00:00

abstract：:Several lines of evidence suggest that formula with protein content of 3.0 g/100 kcal does not fully meet the protein needs of very-low-birth weight infants. Our purpose was to compare nitrogen balance, metabolic status and growth in infants fed a standard (3.0 g/100 kcal; RegPro) and high (3.6 g/100 kcal; HiPro) prot...

journal_title：Pediatric research

authors： Cooke R,Embleton N,Rigo J,Carrie A,Haschke F,Ziegler E

更新日期：2006-02-01 00:00:00

abstract：:Preterm infants are exposed to frequent painful procedures and agitating stimuli over the many weeks of their hospitalization in the neonatal intensive care unit (NICU). The adverse neurobiological impact of pain and stress in the preterm infant has been well documented, including neuroimaging and neurobehavioral outc...

journal_title：Pediatric research

authors： McPherson C,Miller SP,El-Dib M,Massaro AN,Inder TE

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Human milk oligosaccharides (HMOs) shape the intestinal microbiota in term infants. In premature infants, alterations in the intestinal microbiota (dysbiosis) are associated with risk of necrotizing enterocolitis (NEC) and sepsis, and the influence of HMOs on the microbiota is unclear. METHODS:Milk, urine, ...

journal_title：Pediatric research

authors： Underwood MA,Gaerlan S,De Leoz ML,Dimapasoc L,Kalanetra KM,Lemay DG,German JB,Mills DA,Lebrilla CB

更新日期：2015-12-01 00:00:00

abstract：:In its normal circulatory environment, the fetal left ventricle can maximally increase output less than 2-fold, in contrast to the nearly 3-fold increase that occurs at birth. Several studies have attributed this finding to fetal myocardial "immaturity," and speculated that there is a rapid maturation of the myocardiu...

journal_title：Pediatric research

authors： Teitel DF,Dalinghaus M,Cassidy SC,Payne BD,Rudolph AM

更新日期：1991-05-01 00:00:00

abstract：:To assess sleep organization in premature infants of < 35 wk gestational age (w GA), we performed polygraphic recordings in 24 neurologically normal neonates (eight per group): artificially ventilated 27-30 and 31-34 w GA infants and nonventilated 31-34 w GA infants. Sleep states were defined by concordance of EEG and...

journal_title：Pediatric research

authors： Curzi-Dascalova L,Figueroa JM,Eiselt M,Christova E,Virassamy A,d'Allest AM,Guimarâes H,Gaultier C,Dehan M

更新日期：1993-11-01 00:00:00

abstract：:Twenty-four samples of breast milk from nine mothers of infants suffering from breast milk jaundice were studied. Eight samples of milk from mothers of nonjaundiced infants, along with five formula milks enriched with polyunsaturated fatty acids, served as controls. Milks from mothers with jaundiced infants had no inh...

journal_title：Pediatric research

authors： Foliot A,Ploussard JP,Housset E,Christoforov

更新日期：1976-06-01 00:00:00