Neonatal group B streptococcal sepsis: effects of late treatment with dazmegrel.

abstract：:Low IGF-I levels are found in patients with chronic liver disease, but it is not known whether these reductions in IGF-I are secondary to hepatic dysfunction or to malnutrition. To determine whether malnutrition associated with hepatic dysfunction causes the decrease in these levels, serum and liver IGF-I concentratio...

journal_title：Pediatric research

authors： Descos BP,Berry SA,Sharp HL,Gross CR,Weisdorf SA,Pescovitz OH

更新日期：1989-11-01 00:00:00

abstract：:Chitosan is a natural, cationic polysaccharide derived from fully or partially deacetylated chitin. Chitosan is capable of inducing large phospholipid aggregates, closely resembling the function of nonionic polymers tested previously as additives to therapeutic lung surfactants. The effects of chitosan on improving th...

journal_title：Pediatric research

authors： Zuo YY,Alolabi H,Shafiei A,Kang N,Policova Z,Cox PN,Acosta E,Hair ML,Neumann AW

更新日期：2006-08-01 00:00:00

abstract：:The key enzymes in the synthesis of the naturally occurring polyamines, ornithine decarboxylase (ODC) and S-adenosyl methionine (SAM) decarboxylase, were investigated during cell growth and aging in fibroblast cultures from normal patients and patients with cystic fibrosis. A linear correlation between increased S-ade...

journal_title：Pediatric research

authors： Buehler B,Wright R,Schott S,Darby B,Rennert OM

更新日期：1977-03-01 00:00:00

abstract：:A male child presented on the first day of life with metabolic acidosis with elevated blood lactate (15 mM), pyruvate (0.4 mM), and free fatty acid (1.3 mM) levels and a blood pH of 7.16. The severity of the acidosis was diminished by intravenous administration of glucose in large doses and by bicarbonate. On two occa...

journal_title：Pediatric research

authors： Robinson BH,Sherwood WG

更新日期：1975-12-01 00:00:00

abstract：:Premature newborns are highly susceptible to severe bacterial infections. This is partially due to their immature innate immune system, characterized by decreased neutrophil and monocyte activity as well as by reduced concentrations of complement factors. However, additional mechanisms might be important for innate im...

journal_title：Pediatric research

authors： Förster-Waldl E,Sadeghi K,Tamandl D,Gerhold B,Hallwirth U,Rohrmeister K,Hayde M,Prusa AR,Herkner K,Boltz-Nitulescu G,Pollak A,Spittler A

更新日期：2005-07-01 00:00:00

abstract：:Altered transfer of nutrients from mother to conceptus may be involved in the pathogenesis of the developmental disturbances in offspring of diabetic mothers. In our study, the embryonic uptake of a saturated (palmitic acid) and a nonsaturated (arachidonic acid) fatty acid was evaluated in a normal and a diabetes-like...

journal_title：Pediatric research

authors： Engström E,Haglund A,Eriksson UJ

更新日期：1991-08-01 00:00:00

abstract：:The role of microbial colonization is indispensable for keeping a balanced immune response in life. However, the events that regulate the establishment of the microbiota, their timing, and the way in which they interact with the host are not yet fully understood. Factors such as gestational age, mode of delivery, envi...

journal_title：Pediatric research

authors： Collado MC,Cernada M,Neu J,Pérez-Martínez G,Gormaz M,Vento M

更新日期：2015-06-01 00:00:00

abstract：:This prospective randomized pilot study aimed to test the hypotheses that partial liquid ventilation combined with a high positive end-expiratory pressure (PEEP) and a moderate tidal volume results in improved gas exchange and lung mechanics without negative hemodynamic influences compared with conventional mechanical...

journal_title：Pediatric research

authors： Rödl S,Urlesberger B,Knez I,Dacar D,Zobel G

更新日期：2002-08-01 00:00:00

abstract：:Deficiency of the lipoprotein complex, surfactant, can lead to respiratory distress syndrome (RDS) in the prematurely born infant. The surfactant proteins (SP) play important roles in the function of surfactant. Previously, we have characterized four allelic variants of the SP-A1 gene (6A, 6A2, 6A3, and 6A4) and five ...

journal_title：Pediatric research

authors： Kala P,Ten Have T,Nielsen H,Dunn M,Floros J

更新日期：1998-02-01 00:00:00

abstract：:Interrelationships of high-density lipoprotein cholesterol (C-HDL) with total plasma cholesterol (TC), triglyceride, and low-density lipoprotein cholesterol, as well as longitudinal maintenance of C-HDL rank order (tracking) from birth to age 2 years were assessed in 76 hypercholesterolemic neonates (cord blood, TC gr...

journal_title：Pediatric research

authors： Tsang RC,Neely K,Glueck CJ

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Congenital portosystemic shunt (CPSS) has the potential to cause hepatic encephalopathy and thus needs long-term follow-up, but an effective follow-up method has not yet been established. We aimed to evaluate the importance of per-rectal portal scintigraphy (PRPS) for long-term follow-up of CPSS. METHODS:We...

journal_title：Pediatric research

authors： Cho Y,Tokuhara D,Shimono T,Yamamoto A,Higashiyama S,Kotani K,Kawabe J,Okano Y,Shiomi S,Shintaku H

更新日期：2014-05-01 00:00:00

abstract：:Respiratory parameters of skeletal muscle were determined in permeabilized muscle fibers by adapting a technique described by Veksler et al. for cardiac fibers (Biochim Biophys Acta, 892:191-196, 1987). This method consists of the permeabilization of muscle fibers by saponin by allowing respiratory substrates and inhi...

journal_title：Pediatric research

authors： Letellier T,Malgat M,Coquet M,Moretto B,Parrot-Roulaud F,Mazat JP

更新日期：1992-07-01 00:00:00

abstract：:Birth is characterized by swift and complex transitions in hemodynamic and respiratory variables. Unrecognized pathologies or incidents may quickly become fatal or cause permanent damage. This article introduces an essential component of an acute perinatal care simulator, namely a model for educational simulation of n...

journal_title：Pediatric research

authors： Sá-Couto CD,Andriessen P,Van Meurs WL,Ayres-de-Campos D,Sá-Couto PM

更新日期：2010-02-01 00:00:00

abstract：:Fifty patients with haemophilia B, belonging to 29 kindreds, were investigated with a highly sensitive immunoradiometric assay based on a homologous antibody to factor IX. The assay measures factor IX antigen (f.IX:Ag) in plasma down to 0.025 U/dl. Seventeen of 18 investigated patients with severe haemophilia B had ve...

journal_title：Pediatric research

authors： Ljung R,Holmberg L

更新日期：1982-03-01 00:00:00

abstract：:Docosahexaenoic acid (DHA), a 22-carbon, highly unsaturated, n-3 fatty acid, is important for optimal nervous system function. In this study, designed to quantify how preformed dietary DHA regulates metabolic pathways in vivo, 8-d-old rat pups were divided into four groups and fed artificial rat milk diets. One group ...

journal_title：Pediatric research

authors： Lefkowitz W,Lim SY,Lin Y,Salem N Jr

更新日期：2005-01-01 00:00:00

abstract：:This study characterizes cardiorespiratory dysregulation in young girls with MECP2 mutation-confirmed Rett syndrome (RS). Respiratory inductance plethysmography of chest/abdomen and ECG was obtained during daytime wakefulness in 47 girls with MECP2 mutation-confirmed RS and 47 age-, gender-, and ethnicity-matched cont...

journal_title：Pediatric research

authors： Weese-Mayer DE,Lieske SP,Boothby CM,Kenny AS,Bennett HL,Silvestri JM,Ramirez JM

更新日期：2006-10-01 00:00:00

abstract：:Fetuin-A prevents tissue calcification by forming soluble complexes with calcium and phosphate. A pathological depletion of serum fetuin-A has been observed in children on dialysis or after renal transplantation but knowledge on physiologic age-related changes in serum fetuin-A is limited. We prospectively evaluated s...

journal_title：Pediatric research

authors： Häusler M,Schäfer C,Osterwinter C,Jahnen-Dechent W

更新日期：2009-12-01 00:00:00

abstract：:Stimulation of cutaneous thermoreceptors may be an important factor in the initiation of continuous breathing at birth. Maintenance of a patent airway is also important in the continuation of effective ventilation after birth, but whereas in the adult the principal pharyngeal dilator is the genioglossus muscle, in the...

journal_title：Pediatric research

authors： Johnston BM,Gunn TR,Gluckman PD

更新日期：1988-03-01 00:00:00

abstract：:A study using fractional clearances during orally induced water diuresis was designed to delineate the mechanism underlying defective tubular reabsorption of sodium in very low-birth-weight neonates. The use of clearance methodology during maximal water diuresis may give an indirect estimate of distal sodium delivery ...

journal_title：Pediatric research

authors： Rodríguez-Soriano J,Vallo A,Oliveros R,Castillo G

更新日期：1983-12-01 00:00:00

abstract：:The objective of the present study is to compare the emergence of a circadian respiratory pattern in subsequent siblings of SIDS and controls infants to see whether the unique time and age of SIDS is correlated with altered circadian manifestations. During the first three months of life, a pattern in respiratory rates...

journal_title：Pediatric research

authors： Hoppenbrouwers T,Jensen DK,Hodgman JE,Harper RM,Sterman MB

更新日期：1980-04-01 00:00:00

abstract：:Irreversible congenital heart block (CHB) and the transient rash of neonatal lupus are strongly associated with maternal antibodies to SSA/Ro and SSB/La proteins; however, the precise mechanism by which these antibodies mediate organ-specific injury is not yet defined. Culturing of keratinocytes has provided critical ...

journal_title：Pediatric research

authors： Tseng CE,Miranda E,Di Donato F,Boutjdir M,Rashbaum W,Chan EK,Buyon JP

更新日期：1999-02-01 00:00:00

abstract：:Infants fed soy-based infant formulas are exposed to high levels of genistein, an isoflavone, with potential estrogen-like activity. This study determined whether neonatal exposure of mice to genistein resulted in higher bone mineral density (BMD) and greater resistance to fracture at adulthood. Male and female CD-1 m...

journal_title：Pediatric research

authors： Piekarz AV,Ward WE

更新日期：2007-01-01 00:00:00

abstract：:To investigate the detailed pattern of change in circulating gonadotropin and testosterone concentrations around the onset of puberty and to determine the temporal relationship between the gonadotropin and testosterone secretion, plasma gonadotropin and testosterone were measured at 20-min intervals for 24 h in 21 nor...

journal_title：Pediatric research

authors： Goji K,Tanikaze S

更新日期：1993-08-01 00:00:00

abstract：:Severe tetrahydrobiopterin (BH4) deficiency is a naturally occurring model of cerebral catecholamine and serotonin shortage. Examination of the stimulated release and physiologic secretion pattern of several hormones in affected individuals permits certain conclusions concerning the involvement of these neurotransmitt...

journal_title：Pediatric research

authors： Birnbacher R,Scheibenreiter S,Blau N,Bieglmayer C,Frisch H,Waldhauser F

更新日期：1998-04-01 00:00:00

abstract：:We studied choline uptake by slices of adult and 10-day-old rat intestine which were exposed on their mucosal surface to radiolabeled choline. Both neonatal and adult intestine transported choline. Choline uptake was observed in duodenum, jejunum, ileum, and colon of the adult rat. In the small intestine, choline upta...

journal_title：Pediatric research

authors： Sheard NF,Zeisel SH

更新日期：1986-08-01 00:00:00

abstract：:The effect of diet, human milk or formula, on gastric function (lipase and pepsin activity, pH, and volume) and intragastric digestion of fat was assessed in 28 appropriate for gestational age preterm infants (gestational age, 28.9 +/- 1.4, 29.1 +/- 0.9, 29.5 +/- 0.6 wk; birth weight, 1.00 +/- 0.14 to 1.18 +/- 0.07 kg...

journal_title：Pediatric research

authors： Armand M,Hamosh M,Mehta NR,Angelus PA,Philpott JR,Henderson TR,Dwyer NK,Lairon D,Hamosh P

更新日期：1996-09-01 00:00:00

abstract：:Evidence is increasing for a role of polymorphisms in maternal or fetal innate immune response genes in preterm birth. Toll-like receptors (TLRs) are important receptors in the innate immunity. The genotype distribution of two TLR2 single nucleotide polymorphisms (SNPs) and one TLR4 SNP were determined among 524 neona...

journal_title：Pediatric research

authors： Krediet TG,Wiertsema SP,Vossers MJ,Hoeks SB,Fleer A,Ruven HJ,Rijkers GT

更新日期：2007-10-01 00:00:00

abstract：:Uteroplacental insufficiency alters the anabolic metabolism of the fetus, resulting in intrauterine growth retardation (IUGR). The metabolic and physiologic factors that cause IUGR have long standing consequences after birth. Postnatal growth and glucose metabolism are altered in the IUGR infant. Skeletal muscle is an...

journal_title：Pediatric research

authors： Lane RH,Chandorkar AK,Flozak AS,Simmons RA

更新日期：1998-05-01 00:00:00

abstract：:Completely penetrant mutations in the surfactant protein B gene (SFTPB) and >75% reduction of SFTPB expression disrupt pulmonary surfactant function and cause neonatal respiratory distress syndrome. To inform studies of genetic regulation of SFTPB expression, we created a catalogue of SFTPB variants by comprehensive r...

journal_title：Pediatric research

authors： Hamvas A,Wegner DJ,Carlson CS,Bergmann KR,Trusgnich MA,Fulton L,Kasai Y,An P,Mardis ER,Wilson RK,Cole FS

更新日期：2007-08-01 00:00:00

abstract：:Breast-fed infants have higher bilirubin levels than formula-fed infants, possibly because of variations in the composition of the breast milk. The aim of this study was to investigate whether there is a relationship between cytokine levels in the colostrum of nursing mothers and neonatal jaundice (NJ). Breast milk sa...

journal_title：Pediatric research

authors： Zanardo V,Golin R,Amato M,Trevisanuto D,Favaro F,Faggian D,Plebani M

更新日期：2007-08-01 00:00:00