Renal handling of sodium in premature and full-term neonates: a study using clearance methods during water diuresis.

abstract：:Many trials of mesenchymal stem cells (MSCs) have been published in the past 5-6 y. MSCs inhibit T-cell alloreactivity in vitro by soluble factors and direct cell-to-cell contact. They are safe to infuse in humans with no acute toxicity and no ectopic tissue formation. Promising results of MSC infusion for graft-vs.-h...

journal_title：Pediatric research

authors： Dalal J,Gandy K,Domen J

更新日期：2012-04-01 00:00:00

abstract：:Phototherapy results in the conversion of bilirubin to more water-soluble isomers. Six clinically used phototherapy lamps which differ in their emission spectra have been compared in their ability to produce configurational and structural isomers of bilirubin in vitro. For all of the lamps, the initial rate of configu...

journal_title：Pediatric research

authors： Ennever JF,Sobel M,McDonagh AF,Speck WT

更新日期：1984-07-01 00:00:00

abstract：:Cerebral magnetic resonance imaging (MRI) has revealed white matter changes in patients with phenylketonuria (PKU), an inborn error of metabolism with increased plasma phenylalanine level. Because the significance of these lesions is unknown, this study was undertaken to determine whether glucose metabolism was depres...

journal_title：Pediatric research

authors： Hasselbalch S,Knudsen GM,Toft PB,Høgh P,Tedeschi E,Holm S,Videbaek C,Henriksen O,Lou HC,Paulson OB

更新日期：1996-07-01 00:00:00

abstract：:Recent data suggest that umbilical venous perfusion of the fetal liver has an important influence on fetal growth and postnatal liver function, and that maternal factors in late pregnancy modify this circulation. In a longitudinal study of 160 low-risk pregnancies, we determined how umbilical and portal venous blood f...

journal_title：Pediatric research

authors： Kessler J,Rasmussen S,Godfrey K,Hanson M,Kiserud T

更新日期：2008-03-01 00:00:00

abstract：:Serial plasma concentrations of immunoreactive 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), the stable hydration product of prostacyclin (PGI2), were measured with radioimmunoassay during the first month of life in 25 preterm infants with idiopathic respiratory distress syndrome (IRDS) and 38 preterm controls wi...

journal_title：Pediatric research

authors： Kääpä P,Koivisto M,Viinikka L,Ylikorkala O

更新日期：1982-10-01 00:00:00

abstract：:Experiments were done to investigate the effects of increased inspired oxygen on the arousal response from sleep to upper airway obstruction in 10 newborn lambs. Each lamb was anesthetized and instrumented for recordings of electrocorticograms, electrooculogram, nuchal and diaphragm electromyograms, and measurements o...

journal_title：Pediatric research

authors： Baker SB,Fewell JE

更新日期：1987-02-01 00:00:00

abstract：:Newly identified forms of electron transfer flavoprotein (ETF) deficiency in two patients with glutaric aciduria type II (GA II) were described. GA II has been attributed to a defect of either ETF or ETF dehydrogenase, resulting in multiple acyl-CoA dehydrogenation deficiency. ETF is a mitochondrial flavoprotein consi...

journal_title：Pediatric research

authors： Yamaguchi S,Orii T,Suzuki Y,Maeda K,Oshima M,Hashimoto T

更新日期：1991-01-01 00:00:00

abstract：:The mononuclear cells of newborn infants compared to those of normal adults contain diminished activity of pyruvate kinase (PK) (14.9 +/- 1.2 vs. 22.3 +/- 1.3 mumol/10(10) cells/min) and phosphoglycerate kinase (PGK) (195 +/- 10 vs. 415 +/- 19). These deficiencies are accentuated in the cells of premature infants (4.9...

journal_title：Pediatric research

authors： Das M,Klein W,Feig SA

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:Therapeutic hypothermia (HT) is the only intervention that improves outcomes in neonatal hypoxic-ischemic encephalopathy (HIE). However, the multifactorial mechanisms by which HT impacts HIE are incompletely understood. The complement system plays a major role in the pathogenesis of ischemia-reperfusion inju...

journal_title：Pediatric research

authors： Shah TA,Nejad JE,Pallera HK,Lattanzio FA,Farhat R,Kumar PS,Hair PS,Bass WT,Krishna NK

更新日期：2017-04-01 00:00:00

abstract：:To evaluate the maturation of glucose homeostasis in the small for gestational age (SGA) neonate, glucose kinetics were measured with 78% enriched D-[U-13C]glucose by the prime plus constant infusion technique in nine SGA infants and compared with the rate obtained in seven term appropriate for gestational age infants...

journal_title：Pediatric research

authors： Cowett RM,Susa JB,Oh W,Schwartz R

更新日期：1984-01-01 00:00:00

abstract：:Antenatal cocaine administration is associated with increases in catecholamines and glucocorticoids and results in fetal hypoxemia, with the speculated potential for increased free radical formation in the fetus. Because of this, we hypothesized that antenatal cocaine exposure would produce not only accelerated pulmon...

journal_title：Pediatric research

authors： Sosenko IR

更新日期：1993-04-01 00:00:00

abstract：:Carbohydrate and lipid intakes have both been found to modulate the metabolism of long-chain fatty acids. To define the respective influence of these two energy substrates on plasma fatty acid concentrations, 32 studies were performed in 16 parenterally fed newborn infants (mean +/- SEM, birth wt: 2.15 +/- 0.1 kg, age...

journal_title：Pediatric research

authors： Pineault M,Lepage G,Bisaillon S,Roy CC,Chessex P

更新日期：1989-10-01 00:00:00

abstract：:The use of nebulized racemic epinephrine to improve ventilatory function in the newborn postextubation was studied. Forty-five infants intubated for more than 3 days were randomized to receive racemic epinephrine by nebulization immediately postextubation or to receive only warmed, humidified gas. Measurements of air ...

journal_title：Pediatric research

authors： Courtney SE,Wachtl JP,Hopson JF,Siervogel RM

更新日期：1987-04-01 00:00:00

abstract：:We have previously demonstrated that vagal phase-response curves (PRC), which characterize the effects of critically timed, brief vagal stimuli on sinus node automaticity, exhibit a fundamentally different shape in the canine newborn than in the adult. In this study we analyzed the changes in sinus cycle length in res...

journal_title：Pediatric research

authors： Pickoff AS,Rios R,Stolfi A,Wang SN

更新日期：1994-01-01 00:00:00

abstract：:Nasopharyngeal radium irradiation (NRI) was widely used from 1940 through 1970 to treat otitis serosa in children and barotrauma in airmen and submariners. We assessed whether NRI-exposed individuals were at higher risk for benign tumors, nonmelanoma skin cancer, thyroid disorders, and conditions related to regulatory...

journal_title：Pediatric research

authors： Ronckers CM,Land CE,Hayes RB,Verduijn PG,Stovall M,van Leeuwen FE

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:The present study examined the association between 9/11-related adolescent behavioral problems on mental health outcomes in early adulthood. METHODS:Data from enrollees of the World Trade Center Health Registry, who completed at least one adolescent (2006-2007 or 2011-2012) and adult survey (2011-2012 or 20...

journal_title：Pediatric research

authors： Gargano LM,Locke S,Li J,Farfel MR

更新日期：2018-08-01 00:00:00

abstract：:Whether severe hypoglycemia alone or in combination with hyperketonemia might cause deterioration of cardiac function has been controversial. Therefore, the influence of acute hypoglycemia (mean 33 mg/dL) with and without hyperketonemia (mean 1.3 and 3.3 mM) on cardiac function, substrate utilization, and myocardial h...

journal_title：Pediatric research

authors： Breuer J,Chung KJ,Pesonen E,Haas RH,Guth BD,Sahn DJ,Hesselink JR

更新日期：1989-12-01 00:00:00

abstract：:Our aim was to compare white matter (WM) microstructure in preterm infants with and without punctate WM lesions on MRI using tract-based spatial statistics (TBSS) and probabilistic tractography. We studied 23 preterm infants with punctate lesions, median GA at birth 30 (25-35) wk, and 23 GA- and sex-matched preterm co...

journal_title：Pediatric research

authors： Bassi L,Chew A,Merchant N,Ball G,Ramenghi L,Boardman J,Allsop JM,Doria V,Arichi T,Mosca F,Edwards AD,Cowan FM,Rutherford MA,Counsell SJ

更新日期：2011-06-01 00:00:00

abstract：:In view of their known high incidence of noninsulin dependent diabetes (NIDDM), we sought to determine whether Native American (Plains Indian) children and adolescents show evidence of risk factors for both NIDDM and cardiovascular disease. Children and adolescents between the ages of 4 and 19 y were recruited, and fi...

journal_title：Pediatric research

authors： Blackett PR,Taylor T,Russell D,Lu M,Fesmire J,Lee ET

更新日期：1996-07-01 00:00:00

abstract：:Previous studies have demonstrated metabolic dysfunction in the mononuclear cells of some children with abnormal cell-mediated immunity. Interpretation of these observations has been complicated by the extreme heterogeneity of cell types examined. The glycolytic metabolism of relatively enriched T-cells, non-T mononuc...

journal_title：Pediatric research

authors： Storch S,Klein W,Feig SA,Henderson T

更新日期：1980-02-01 00:00:00

abstract：:The aim of the present study was to determine the proportion of gamma/delta T-lymphocytes and CD16/CD56 (CD3- and CD3+) cells in the peripheral blood of children and adolescents with Graves' disease (GD; n = 27; mean age, 15.5 +/- 5.1 y) and nontoxic nodular goiter (NTNG; n = 25; mean age, 15.2 +/- 5.7 y), in comparis...

journal_title：Pediatric research

authors： Bossowski A,Urban M,Stasiak-Barmuta A

更新日期：2003-09-01 00:00:00

abstract：:We injected 3-day-old (neonatal), 8-day-old (infant), and 8-wk-old (adult) Sprague-Dawley rats with monocrotaline to examine the effect of a toxic agent at various stages of lung development. Two and four weeks after injection the rats were killed and the heart and lungs removed: the right and left ventricles were sep...

journal_title：Pediatric research

authors： Todd L,Mullen M,Olley PM,Rabinovitch M

更新日期：1985-07-01 00:00:00

abstract：:Pesticides are chemicals that are designed specifically for the purpose of killing or suppressing another living organism. Human toxicity is possible with any pesticide, and a growing body of literature has investigated possible associations with neurodevelopmental disorders. Attention deficit disorder with or without...

journal_title：Pediatric research

authors： Roberts JR,Dawley EH,Reigart JR

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Near-infrared spectroscopy (NIRS) is an upcoming clinical method for monitoring regional cerebral oxygen saturation (rScO2) in neonates. There is a growing market offering different devices and sensors. Even though this technique is increasingly clinically applied, little is known about the similarities and/...

journal_title：Pediatric research

authors： Dix LM,van Bel F,Baerts W,Lemmers PM

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Postnatal growth restriction (PNGR) in premature infants increases risk of pulmonary hypertension (PH). In a rodent model, PNGR causes PH, while combining PNGR and hyperoxia increases PH severity. We hypothesized that PNGR causes intestinal dysbiosis and that treatment with a probiotic attenuates PNGR-associ...

journal_title：Pediatric research

authors： Wedgwood S,Warford C,Agvatisiri SR,Thai PN,Chiamvimonvat N,Kalanetra KM,Lakshminrusimha S,Steinhorn RH,Mills DA,Underwood MA

更新日期：2020-02-01 00:00:00

abstract：:Nutrition in early life, growth, and subsequent health over a lifetime are significantly interrelated. The aim of this study was to assess body composition changes in exclusively breast-fed infants from birth up to 6 mo of age. An observational, prospective, cohort study was conducted. Fifty-nine full-term, healthy, e...

journal_title：Pediatric research

authors： Roggero P,Giannì ML,Orsi A,Piemontese P,Amato O,Liotto N,Morlacchi L,Taroni F,Fields DA,Catalano PM,Mosca F

更新日期：2010-12-01 00:00:00

abstract：:The regionalization of pediatric services has resulted in differential access to care, sometimes creating barriers to those living in underserved, rural communities. These disparities in access contribute to inferior healthcare outcomes among infants and children. We review the medical literature on telemedicine and i...

journal_title：Pediatric research

authors： Marcin JP,Shaikh U,Steinhorn RH

更新日期：2016-01-01 00:00:00

abstract：:Infants with polycythemia and hyperviscosity are known to have a reduced cerebral blood flow. Eight newborn lambs were studied to determine what effect the reduction in cerebral blood flow might have on the cerebral delivery and uptake of oxygen, glucose, lactate, pyruvate, beta-hydroxybutyrate, and acetoacetate. Meas...

journal_title：Pediatric research

authors： Rosenkrantz TS,Philipps AF,Skrzypczak PS,Raye JR

更新日期：1988-03-01 00:00:00

abstract：:There are substantial alterations in fuel homeostasis immediately after birth. Leptin is a putative regulator of energy metabolism. Consequently, the aim of this study was to examine whether there are changes in circulating leptin concentrations during the early postnatal period. Umbilical cord mixed blood samples wer...

journal_title：Pediatric research

authors： Hytinantti T,Koistinen HA,Koivisto VA,Karonen SL,Andersson S

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Although cardiopulmonary bypass (CPB) has been previously studied as risking infection and inflammatory responses, few studies evaluate the relationship of preoperative high total immunoglobulin E (tIgE) to outcomes in pediatric patients predisposed to atopy undergoing cardiac surgery with CPB. METHODS:Seru...

journal_title：Pediatric research

authors： Li Y,Zhu L,Chen J,Singson MTG,Rui X,Li N,Zhou L,Liu J

更新日期：2018-11-01 00:00:00