Therapeutic hypothermia modulates complement factor C3a and C5a levels in a rat model of hypoxic ischemic encephalopathy.

abstract：:The response of cerebral blood volume (CBVR) to a small induced change in arterial carbon dioxide tension was studied by near-infrared spectroscopy in 17 newborn infants born from 26 wk of gestation to term. All 17 infants were undergoing mechanical ventilation but had apparently normal brains. The CBVR per kPa change...

journal_title：Pediatric research

authors： Wyatt JS,Edwards AD,Cope M,Delpy DT,McCormick DC,Potter A,Reynolds EO

更新日期：1991-06-01 00:00:00

abstract：:We investigated the role of circulating bone marrow cells (BMC) in cardiomyocyte regeneration. BMC, isolated from transgenic mice expressing enhanced green fluorescent protein (GFP), were transplanted into lethally irradiated C57BL6 mice. Five weeks after bone marrow transplantation (BMT), flow cytometric analysis for...

journal_title：Pediatric research

authors： Kuramochi Y,Fukazawa R,Migita M,Hayakawa J,Hayashida M,Uchikoba Y,Fukumi D,Shimada T,Ogawa S

更新日期：2003-09-01 00:00:00

abstract：:Human GH is encoded by the GH-1 gene which belongs to the GH gene cluster encompassing a distance of about 65 kb on the long arm of chromosome 17. Familial isolated growth hormone deficiency (IGHD) is associated with at least four Mendelian disorders. These include two forms that have autosomal recessive inheritance (...

journal_title：Pediatric research

authors： Wagner JK,Eblé A,Hindmarsh PC,Mullis PE

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Bilirubin-induced neurologic dysfunction (BIND) is a spectrum of preventable neurological sequelae in jaundiced newborns. Current total plasma bilirubin (BT) concentration thresholds for phototherapy and/or exchange transfusion poorly predict BIND. METHODS:The unbound (free) bilirubin (Bf) measured at these...

journal_title：Pediatric research

authors： Ahlfors CE,Bhutani VK,Wong RJ,Stevenson DK

更新日期：2018-10-01 00:00:00

abstract：:The development of metabolic acidosis during neonatal sepsis with group B streptococci (GBS) has been attributed to progressive tissue ischemia resulting from reduced oxygen delivery (QO2). Using an animal model of GBS disease, we attempted to test this hypothesis by comparing the development of metabolic acidosis in ...

journal_title：Pediatric research

authors： Meadow WL,Rudinsky BF,Strates E,Komar KJ

更新日期：1987-11-01 00:00:00

abstract：:In the human fetus, liver macrophages appear to be the primary source of erythropoietin (Epo). Epo production shifts from the liver to peritubular cells in the kidney sometime during the 3rd trimester. Some preterm infants experience a hyporegenerative anemia that appears to be caused by inadequate Epo production. It ...

journal_title：Pediatric research

authors： Ohls RK,Li Y,Trautman MS,Christensen RD

更新日期：1994-02-01 00:00:00

abstract：:BackgroundCaffeine promotes spontaneous breathing by antagonizing adenosine. We assessed the direct effect of caffeine on respiratory effort in preterm infants at birth.MethodsThirty infants of 24-30 weeks of gestation were randomized for receiving caffeine directly after birth in the delivery room (caffeine DR group)...

journal_title：Pediatric research

authors： Dekker J,Hooper SB,van Vonderen JJ,Witlox RSGM,Lopriore E,Te Pas AB

更新日期：2017-08-01 00:00:00

abstract：:A comparative study of two smallpox vaccines, standard calf lymph vaccine, and an attenuated vaccine, CVI-78, was performed in 95 children. Primary vaccination with CVI-78 resulted in a more attenuated response than primary vaccination with standard vaccine. Sixty-one percent of those vaccinated with CVI-78 and 96 per...

journal_title：Pediatric research

authors： Wesley RB,Speers WC,Neff JM,Ruben FL,Lourie B

更新日期：1975-08-01 00:00:00

abstract：:We investigated the early postnatal changes of the mesenteric circulation and its relation to the systemic circulation in 15 preterm infants. The infants were studied before the first feeding on d 1 and pre- and postprandially on d 3, 4, 5, and 7. Blood flow velocity was measured by ultrasound Doppler in the superior ...

journal_title：Pediatric research

authors： Martinussen M,Brubakk AM,Vik T,Yao AC

更新日期：1996-02-01 00:00:00

abstract：:Vascular dopamine (DA1) receptors may modulate circulatory hemodynamics in lambs. We evaluated resting dopaminergic tone in lambs by pharmacologically manipulating peripheral DA1 receptors with i.v. SCH 23390, (a highly selective, competitive DA1 receptor antagonist) and i.v. fenoldopam, (a highly selective DA1 recept...

journal_title：Pediatric research

authors： Polak MJ,Drummond WH

更新日期：1993-02-01 00:00:00

abstract：:Increased concentrations of carcinoembryonic antigen (CEA) have been reported in the sera and sputum of patients with cystic fibrosis. We have found significantly higher concentrations of CEA in both extracted and unextracted saliva of patients with cystic fibrosis compared to age-matched controls and a comparable gro...

journal_title：Pediatric research

authors： MacSween JM,Gillespie CT

更新日期：1980-03-01 00:00:00

abstract：:This paper has been retracted at the request of the authors. ...

journal_title：Pediatric research

authors： Choi CW,Kim BI,Mason SN,Potts-Kant EN,Brahmajothi MV,Auten RL

更新日期：2019-11-01 00:00:00

abstract：:Studies were conducted to assess the efficacy and safety of a synthetic peptide-containing surfactant in the treatment of respiratory distress syndrome (RDS) in preterm (approximately 80% of normal gestation) infant rhesus monkeys. Surfactant was prepared consisting of the phospholipids dipalmitoylphosphatidyl choline...

journal_title：Pediatric research

authors： Revak SD,Merritt TA,Cochrane CG,Heldt GP,Alberts MS,Anderson DW,Kheiter A

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:To systematically evaluate short-term efficacy of UCM versus other interventions in preterm infants. METHODS:Six engines were searched until February 2020 for randomized controlled trials (RCTs) assessing UCM versus immediate cord clamping (ICC), delayed cord clamping (DCC), or no intervention. Primary outc...

journal_title：Pediatric research

authors： Barboza JJ,Albitres-Flores L,Rivera-Meza M,Rodriguez-Huapaya J,Caballero-Alvarado J,Pasupuleti V,Hernandez AV

更新日期：2020-04-21 00:00:00

abstract：:Twenty-four samples of breast milk from nine mothers of infants suffering from breast milk jaundice were studied. Eight samples of milk from mothers of nonjaundiced infants, along with five formula milks enriched with polyunsaturated fatty acids, served as controls. Milks from mothers with jaundiced infants had no inh...

journal_title：Pediatric research

authors： Foliot A,Ploussard JP,Housset E,Christoforov

更新日期：1976-06-01 00:00:00

abstract：:Tracheal epithelial cells obtained from adult and infant ferrets were grown in primary culture in vitro. Cells from adult animals grew readily, and many ciliated cells were observed in the cultures. Successful cultures were derived from infant animals, but cell number in infant and adult cultures began to decrease aft...

journal_title：Pediatric research

authors： Kercsmar CM,Chung Y,Davis PB

更新日期：1991-07-01 00:00:00

abstract：:Long chain polyunsaturated fatty acids (LCPUFA)seem to be the most trophic macronutrients in inducing intestinal adaptation in adult short bowel syndrome (SBS), although their effects on intestinal adaptation in infants with SBS remain unknown.It is hypothesized that a high fat diet enriched with n-3 LCPUFA derived fr...

journal_title：Pediatric research

authors： Yang Q,Kock ND

更新日期：2010-09-01 00:00:00

abstract：:Extracellular glutathione peroxidase (E-GPx) is a selenoenzyme that reduces hydrogen peroxide and organic peroxides. All plasma glutathione peroxidase (GPx) activity in humans is attributable to E-GPx. The gastrointestinal (GI) tract also synthesizes and secretes E-GPx into the extracellular milieu. Endogenously gener...

journal_title：Pediatric research

authors： Tham DM,Whitin JC,Cohen HJ

更新日期：2002-05-01 00:00:00

abstract：:Sildenafil (Viagra) has been shown to be an effective pulmonary vasodilator and is increasingly used in patients with pulmonary hypertension. Its effects on the cerebral circulation are unclear and have not yet been described. We investigated the effect of i.v. sildenafil treatment on cerebral oxygenation in 13 childr...

journal_title：Pediatric research

authors： Nagdyman N,Fleck T,Bitterling B,Ewert P,Abdul-Khaliq H,Stiller B,Hübler M,Lange PE,Berger F,Schulze-Neick I

更新日期：2006-03-01 00:00:00

abstract：:BACKGROUNDLow birth weight is associated with childhood stunting, but equivalent associations for birth body composition (BC) remain unknown. The aim of this study was to assess associations between birth BC and height-for-age z-score (HAZ) at 2 years of age.METHODSIn a prospective cohort study, fat mass (FM) and fat-...

journal_title：Pediatric research

authors： Admassu B,Wells JCK,Girma T,Andersen GS,Owino V,Belachew T,Michaelsen KF,Abera M,Wibaek R,Friis H,Kæstel P

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Gender is increasingly recognized as an important influence on brain development, disease susceptibility, and response to pharmacologic/rehabilitative treatments. In regenerative medicine, it remains entirely unknown whether there is an interaction between transplanted stem cells and host gender that might b...

journal_title：Pediatric research

authors： Ashwal S,Ghosh N,Turenius CI,Dulcich M,Denham CM,Tone B,Hartman R,Snyder EY,Obenaus A

更新日期：2014-05-01 00:00:00

abstract：:In Brazil, similar intrauterine growth restriction (IUGR) rates were observed between cities with distinct levels of socioeconomic development, challenging the current knowledge that higher rates of IUGR would necessarily be observed in poorer areas than in wealthier ones. Ribeirão Preto, a city located in the most de...

journal_title：Pediatric research

authors： De Farias Aragão VM,Barbieri MA,Moura Da Silva AA,Bettiol H,Ribeiro VS

更新日期：2005-05-01 00:00:00

abstract：:The immunological competence of neonatal rabbits inoculated intradermally with Treponema pallidum was examined. Both cellular responses and the production of humoral antibody to specific T. pallidum antigens and to nonspecific antigens or mitogens were investigated. In blast transformation assays, splenic and poplitea...

journal_title：Pediatric research

authors： Gamboa D,Miller JN,Lukehart SA,Baker-Zander SA,Sell S

更新日期：1984-10-01 00:00:00

abstract：:Branching morphogenesis, defined as growth and branching of epithelial tubules during embryogenesis, is a fundamental feature of renal, lung, mammary gland, submandibular gland, and pancreatic morphogenesis in mammals. Disruption of branching morphogenesis has been demonstrated to result in maldevelopment of some of t...

journal_title：Pediatric research

authors： Hu MC,Rosenblum ND

更新日期：2003-10-01 00:00:00

abstract：:We studied healthy and saline lavaged rabbits during high frequency oscillatory ventilation to determine what combination of frequency (f), tidal volume (Vt), and mean airway pressure (Paw) produced the lowest peak-to-peak alveolar pressure amplitude (Palv) and physiologic blood gas tensions. Sinusoidal volume changes...

journal_title：Pediatric research

authors： Kamitsuka MD,Boynton BR,Villanueva D,Vreeland PN,Frantz ID 3rd

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:A lack of consensus exists as to the timing of kidney biopsy in children with steroid-dependent nephrotic syndrome (SDNS) where minimal change disease (MCD) predominates. This study aimed at examining the applicability of a biomarker-assisted risk score model to select SDNS patients at high risk of focal seg...

journal_title：Pediatric research

authors： Chan CY,Resontoc LP,Qader MA,Chan YH,Liu ID,Lau PY,Than M,Yeo WS,Loh AH,Tan PH,Wei C,Reiser J,Biswas SK,Ng KH,Yap HK

更新日期：2019-03-01 00:00:00

abstract：:To determine the influence of an altered carotid body function on the laryngeal chemoreflex (LCR) response, reflex apnea was induced by laryngeal water stimulation during normoxia or acute hypoxia in unanesthetized awake lambs in which the ventilatory response to acute hypoxia was attenuated by prolonged postnatal hyp...

journal_title：Pediatric research

authors： Sladek M,Grogaard JB,Parker RA,Sundell HW

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Prematurity may influence the levels of amino acids, enzymes, and endocrine markers obtained through newborn screening. Identifying which analytes are the most affected by degree of prematurity could provide insight into how prematurity impacts metabolism. METHODS:Analytes from blood spots assayed by Newbor...

journal_title：Pediatric research

authors： Wilson K,Hawken S,Ducharme R,Potter BK,Little J,Thébaud B,Chakraborty P

更新日期：2014-02-01 00:00:00

abstract：:A 10-year longitudinal study was conducted on 16 prepubescent youngsters who had undergone successful weight reduction. Their ages ranged from 2 to 10 years when the study began. In all subjects, weight reduction proceeded only by a decrease in adipose cell size (from 0.62 +/- 0.02 to 0.46 +/- 0.02 micrograms lipid pe...

journal_title：Pediatric research

authors： Ginsberg-Fellner F,Knittle JL

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:We previously demonstrated that the proliferative response to lipopolysaccharide (LPS) in cord blood mononuclear cells (CBMCs) is negatively correlated with the induced expression of interleukin (IL)-4. Our aim, therefore, was to examine whether an impaired cellular response to LPS in infancy is associated w...

journal_title：Pediatric research

authors： Goldberg MR,Elizur A,Luknar-Gabor N,Koch P,Tovbin J,Katz Y

更新日期：2013-08-01 00:00:00