Behavior problems in adolescence and subsequent mental health in early adulthood: results from the World Trade Center Health Registry Cohort.

abstract：BACKGROUND:Although it is commonly accepted that upper airway obstruction (UAO) increases gastroesophageal reflux (GER), the link is poorly understood and insufficiently documented. In addition, while hypoxia is often encountered in infants with UAO, its consequences on GER are virtually unknown. The two aims of the pr...

journal_title：Pediatric research

authors： Michaud A,Jia WL,Djeddi D,Samson N,Nadeau C,Geha S,Praud JP

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Macrosomia and child obesity are growing health-care issues worldwide. The purpose of the study was to evaluate how extremely high or low birth weight affects metabolic markers evaluated in newborn screening. METHODS:The study was register-based and included full-term singletons born in Iceland from 2009 to...

journal_title：Pediatric research

authors： Vidarsdottir H,Thorkelsson T,Halldorsson TI,Bjarnason R,Geirsson RT,Rinaldo P,Franzson L

更新日期：2020-06-29 00:00:00

abstract：:Wolfram syndrome 1 (WS1) is a rare autosomal recessive neurodegenerative disease characterized by diabetes insipidus, diabetes mellitus, optic atrophy, deafness, and other abnormalities. WS1 usually results in death before the age of 50 years. The pathogenesis of WS1 is ascribed to mutations of human WFS1 gene on chro...

journal_title：Pediatric research

authors： Rigoli L,Bramanti P,Di Bella C,De Luca F

更新日期：2018-05-01 00:00:00

abstract：:Opsonisation of heat-killed bakers yeast and C3 and C4 concentrations were determined in sera from 69 children with liver disease and 39 controls as simple screening procedures for abnormalities in the complement system. Where significant defects in these moieties were encountered, the activity of the following was me...

journal_title：Pediatric research

authors： Larcher VF,Wyke RJ,Vergani D,Mowat AP,Williams R

更新日期：1983-04-01 00:00:00

abstract：:The length of the Y chromosome was measured in 42 black patients with trisomy 21 (47,XY,+21) and a similar number of normal individuals of American black ancestry. The length of the Y was expressed as a function of Y/F ratio and arbitrarily classified into five groups using subjectively defined criteria as follows: ve...

journal_title：Pediatric research

authors： Verma RS,Huq A,Madahar C,Qazi Q,Dosik H

更新日期：1982-09-01 00:00:00

abstract：:Hypoxic-ischemic injuries can evolve over several days, and recent studies suggest that further neuronal death may occur 6 to 72 h later. Because cerebral temperature is an important determinant of outcome during the primary injury, we investigated the effect of temperature, on outcome, during the later phases of inju...

journal_title：Pediatric research

authors： Sirimanne ES,Blumberg RM,Bossano D,Gunning M,Edwards AD,Gluckman PD,Williams CE

更新日期：1996-04-01 00:00:00

abstract：:The response of cerebral blood volume (CBVR) to a small induced change in arterial carbon dioxide tension was studied by near-infrared spectroscopy in 17 newborn infants born from 26 wk of gestation to term. All 17 infants were undergoing mechanical ventilation but had apparently normal brains. The CBVR per kPa change...

journal_title：Pediatric research

authors： Wyatt JS,Edwards AD,Cope M,Delpy DT,McCormick DC,Potter A,Reynolds EO

更新日期：1991-06-01 00:00:00

abstract：:Gluconeogenesis decreases during septic shock, but its mechanism is not well known. Tumor necrosis factor alpha (TNF-alpha), which is a key cytokine in septic shock, can increase GLUT1 gene expression and glucose uptake in muscles and fatty tissues. TNF-alpha does not alter the metabolism of hepatocytes in which GLUT2...

journal_title：Pediatric research

authors： Goto M,Yoshioka T,Battelino T,Ravindranath T,Zeller WP

更新日期：2001-04-01 00:00:00

abstract：:Prenatal exposure to infection and subsequent inflammatory responses have been implicated in the etiology of schizophrenia and autism. In this review, we summarize current evidence from human and animal studies supporting the hypothesis that the pathogenesis of these two disorders is linked via exposure to inflammatio...

journal_title：Pediatric research

authors： Meyer U,Feldon J,Dammann O

更新日期：2011-05-01 00:00:00

abstract：:Sildenafil (Viagra) has been shown to be an effective pulmonary vasodilator and is increasingly used in patients with pulmonary hypertension. Its effects on the cerebral circulation are unclear and have not yet been described. We investigated the effect of i.v. sildenafil treatment on cerebral oxygenation in 13 childr...

journal_title：Pediatric research

authors： Nagdyman N,Fleck T,Bitterling B,Ewert P,Abdul-Khaliq H,Stiller B,Hübler M,Lange PE,Berger F,Schulze-Neick I

更新日期：2006-03-01 00:00:00

abstract：:The microchemical study of growth cartilage biopsies may improve the classification and the genetic advice of some types of growth disturbances and contribute to the understanding of biochemical defects. Small tibial growth cartilage biopsies were performed during orthopedic surgery in cases with achondroplasia, pseud...

journal_title：Pediatric research

authors： Stanescu V,Maroteaux P

更新日期：1975-10-01 00:00:00

abstract：:Epidermal growth factor (EGF), a potent mitogen present in milk, is postulated to play an important physiologic role in the ontogeny of the intestine. An artificial rat milk, free of EGF, was developed and fed to newborn rats in an effort to evaluate the physiologic role of EGF on intestinal glucose transport. Compari...

journal_title：Pediatric research

authors： Greene HL,Moore MC,Said HM,Ghishan FK,Orth DN

更新日期：1987-04-01 00:00:00

abstract：:The relationship between the development of cytotoxic cellular immune response to herpes simplex virus type I (HSV-1)-infected autologous cells and the production of interferon (IFN) was studied using in vitro secondary sensitization of peripheral blood leukocytes in subjects with recurrent herpes labialis (RHL) and i...

journal_title：Pediatric research

authors： Tsutsumi H,Bernstein JM,Riepenhoff-Talty M,Ogra PL

更新日期：1986-09-01 00:00:00

abstract：:Two infants with disorders of propionate metabolism were studied at 7 months of age to determine optimum levels of intake of protein and calories to meet the requirements for essential amino acid for growth in infancy, and at the same time minimize the accumulation of toxic intermediates. An effect of alanine was foun...

journal_title：Pediatric research

authors： Kelts DG,Ney D,Bay C,Saudubray JM,Nyhan WL

更新日期：1985-01-01 00:00:00

abstract：:The development of the intestinal mucosal immune barrier is an important protective adaptation for postnatal life. The distribution and phenotype of T and B lymphocytes in human fetal intestine and lymphoid tissues have been characterized and compared to the distribution and phenotype of lymphocytes in postnatal intes...

journal_title：Pediatric research

authors： Russell GJ,Bhan AK,Winter HS

更新日期：1990-03-01 00:00:00

abstract：:In dissociated whole brain cell cultures from newborn mice, we have previously shown that during glucose deprivation under normoxia, D-beta-hydroxybutyrate and oleic acid are increasingly used for energy production. We now asked whether this glucose dependency of the utilization of D-beta-hydroxybutyrate and oleic aci...

journal_title：Pediatric research

authors： Bossi E,Kohler E,Herschkowitz N

更新日期：1989-11-01 00:00:00

abstract：:Conversion of adenosine to inosine is decreased in adenosine deaminase (ADA)-deficient fibroblasts at all concentrations of adenosine tested. Adenosine is not differentially toxic to ADA-deficient fibroblasts except at very high (5 X 10(-4) -1 X 10(-3) M) adenosine levels. Conversion of [14C] adenosine to GTP is not d...

journal_title：Pediatric research

authors： Benke PJ,Dittmar D

更新日期：1976-07-01 00:00:00

abstract：:The sp act of galactose-1-phosphate uridyltransferase has been measured in individual regions of adult rat brain to see if site-specific differences in enzyme activity can aid in the understanding of brain abnormalities observed in well-treated galactosemic patients. The sp act in the cerebellum, brain stem, and midbr...

journal_title：Pediatric research

authors： Rogers S,Heidenreich R,Mallee J,Segal S

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Serum caffeine concentrations >20 μg/ml (100 μmol/l) in infants treated for apnea of prematurity increases TNF-α and decreases IL-10, changes that perhaps are linked to comorbidities. We hypothesize that this proinflammatory cytokine profile may be linked to differential binding of caffeine to adenosine rece...

journal_title：Pediatric research

authors： Chavez-Valdez R,Ahlawat R,Wills-Karp M,Gauda EB

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Insulin-like growth factor (IGF)-I and -II play an important role in prenatal growth. During the first 2 months from birth, body fat doubles, and rapid weight gain during this time increases future risk of cardiometabolic disease. The aim of this study was to determine whether IGF measurements at birth assoc...

journal_title：Pediatric research

authors： Hawkes CP,Grimberg A,Kenny LC,Kiely M,Hourihane JOB,Irvine AD,McPhaul MJ,Caulfield MP,Zemel BS,Murray DM

更新日期：2019-04-01 00:00:00

abstract：:Circadian rhythms of plasma renin activity (PRA) and plasma aldosterone (PA) were studied in eight healthy children, 7 to 15 years old. Blood samples were obtained at 7:00 AM, 10:00 AM, 1:00 PM, 4:00 PM, 5:00 PM, 8.00 PM, and midnight on day 1 and 4:00 AM and 7:00 AM on day 2. Children had normal activity during this ...

journal_title：Pediatric research

authors： Dechaux M,Broyer M,Lenoir G,Limal JM,Sachs C

更新日期：1982-05-01 00:00:00

abstract：:The perinatal ontogeny of preprotachykinin-A gene expression was assessed in central respiration-related structures. On the day of birth, there was an enhanced expression of preprotachykinin-A mRNA in the region of the nucleus tractus solitarii, the primary relay station for respiratory and cardiovascular reflexes. Th...

journal_title：Pediatric research

authors： Srinivasan M,Yamamoto Y,Persson H,Lagercrantz H

更新日期：1991-04-01 00:00:00

abstract：:Plasma selenium concentration and glutathione peroxidase activity in red blood cells were determined in subjects from different age groups. The selenium level (mean +/- SD) found in infancy (0 to 6 months) was 2 +/- 0.6 micrograms/dl, with the lowest value of 1 microgram/dl observed in a 4-month-old infant. These leve...

journal_title：Pediatric research

authors： van Caillie-Bertrand M,Degenhart HJ,Fernandes J

更新日期：1986-06-01 00:00:00

abstract：:Prenatal maternal therapy with glucocorticoid reduces the incidence of respiratory distress syndrome (RDS) in premature infants. To investigate the effects of this treatment on the fetal endocrine system, we determined serum concentrations of betamethasone, cortisol, dehydroepiandrosterone sulfate, growth hormone, and...

journal_title：Pediatric research

authors： Ballard PL,Gluckman PD,Liggins GC,Kaplan SL,Grumbach MM

更新日期：1980-02-01 00:00:00

abstract：:The use of erythrocyte entrapment as a strategy to deliver and protect exogenously administered enzymes for replacement therapy in selected genetic diseases has been evaluated in a mammalian model system. The uptake, tissue distribution, intracellular localization, and in vivo lifetime of erythrocyte-entrapped bovine ...

journal_title：Pediatric research

authors： Thorpe SR,Fiddler MB,Desnick RJ

更新日期：1975-12-01 00:00:00

abstract：:Guinea pig gallbladder smooth muscle contractility undergoes a period of postnatal maturation. Because tissues from adult animals contract more forcefully than tissues from newborn animals when stimulated with agonists that activate the contractile process through different mechanisms (receptor activation, membrane de...

journal_title：Pediatric research

authors： Lambert R,Ryan JP

更新日期：1990-10-01 00:00:00

abstract：:A method is developed for the detection of homozygotes and heterozygote carriers of Niemann-Pick disease type A by employing a high performance liquid chromatography (HPLC) technique for the measurement of sphingomyelin (SP) as well as for the assay of the enzyme sphingomyelinase (SPase) in skin fibroblasts and amniot...

journal_title：Pediatric research

authors： Jungalwala FB,Milunsky A

更新日期：1978-05-01 00:00:00

abstract：:Children with inborn errors of urea synthesis who survive neonatal hyperammonemic coma commonly exhibit cognitive deficits and neurologic abnormalities. Yet, there is evidence that ammonia is not the only neurotoxin. Hyperammonemia appears to induce a number of neurochemical alterations. In rodent models of hyperammon...

journal_title：Pediatric research

authors： Robinson MB,Heyes MP,Anegawa NJ,Gorry E,Djali S,Mellits ED,Batshaw ML

更新日期：1992-10-01 00:00:00

abstract：:There is significant uncertainty over the role of assessment of long-term neurodevelopmental outcome (LTO) in neonatal clinical trials. A multidisciplinary working group was established to identify key issues in this area and to make recommendations about optimal approaches to evaluate LTO in therapeutic trials in new...

journal_title：Pediatric research

authors： Marlow N,Doyle LW,Anderson P,Johnson S,Bhatt-Mehta V,Natalucci G,Darlow BA,Davis JM,Turner MA,International Neonatal Consortium (INC).

更新日期：2019-11-01 00:00:00

abstract：:An alteration in head position, which effects cerebral blood flow, may increase the risk for intraventricular hemorrhage in the critically ill infant. The purpose of this study was to evaluate in vivo cerebral oxidative metabolism as an index of tissue oxygen delivery reflecting brain blood flow, in healthy preterm an...

journal_title：Pediatric research

authors： Lawson B,Anday E,Guillet R,Wagerle LC,Chance B,Delivoria-Papadopoulos M

更新日期：1987-09-01 00:00:00