Brain oxidative phosphorylation following alteration in head position in preterm and term neonates.

abstract：:Alterations of the architecture of cerebral white matter in the developing human brain can affect cortical development and result in functional disabilities. A line scan diffusion-weighted magnetic resonance imaging (MRI) sequence with diffusion tensor analysis was applied to measure the apparent diffusion coefficient...

journal_title：Pediatric research

authors： Hüppi PS,Maier SE,Peled S,Zientara GP,Barnes PD,Jolesz FA,Volpe JJ

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Pediatric myocarditis is a rare disease with substantial mortality. Little is known regarding its prognostic factors. We hypothesize that certain comorbidities and procedural needs may increase risks of poor outcomes. This study aims to identify prognostic factors for pediatric myocarditis. METHODS:The nati...

journal_title：Pediatric research

authors： Chou FS,Ghimire LV

更新日期：2020-11-18 00:00:00

abstract：BACKGROUND:Serum caffeine concentrations >20 μg/ml (100 μmol/l) in infants treated for apnea of prematurity increases TNF-α and decreases IL-10, changes that perhaps are linked to comorbidities. We hypothesize that this proinflammatory cytokine profile may be linked to differential binding of caffeine to adenosine rece...

journal_title：Pediatric research

authors： Chavez-Valdez R,Ahlawat R,Wills-Karp M,Gauda EB

更新日期：2016-07-01 00:00:00

abstract：:Plasma, amniotic fluid, and tissue concentrations of IGF-I were examined in nutritionally deprived, growth-retarded fetal rats to determine whether IGF-I concentration serves as a marker for nutritional status. Growth retardation was induced by 72 h of maternal fasting. Twenty-three control and 17 growth-retarded fetu...

journal_title：Pediatric research

authors： Bernstein IM,DeSouza MM,Copeland KC

更新日期：1991-08-01 00:00:00

abstract：:Infection with human immunodeficiency virus (HIV) causes a progressive immunodeficiency, often manifested in adults by the development of infections with relatively rare, opportunistic organisms. However, in HIV-infected children, recurrent serious infections with common encapsulated bacteria, as well as recurrent min...

journal_title：Pediatric research

authors： Mofenson LM,Moye J Jr

更新日期：1993-01-01 00:00:00

abstract：:Blue and white phototherapy was given to infant (and weanling) homozygous Gunn rats treated with different doses of riboflavin-5-phosphate (ribofl.5'p.) During the first hours after a flavin-injection, the effect of phototherapy with both types of fluorescent lamps was enhanced. With equal radiant power applied, the s...

journal_title：Pediatric research

authors： Ballowitz L,Bunjamin A,Hanefeld F,Lietz L,Stüttgen G,Wirjadi D

更新日期：1979-12-01 00:00:00

abstract：:Keratinocyte growth factor (KGF, or fibroblast growth factor 7) was previously reported to enhance the synthesis of surfactant in alveolar type II cells. We investigated the possible interactions between KGF and a glucocorticoid, dexamethasone (Dex), on surfactant protein (SP) gene expression. In cultured fetal rat ty...

journal_title：Pediatric research

authors： Mouhieddine-Gueddiche OB,Pinteur C,Chailley-Heu B,Barlier-Mur AM,Clement A,Bourbon JR

更新日期：2003-02-01 00:00:00

abstract：:A method is developed for the detection of homozygotes and heterozygote carriers of Niemann-Pick disease type A by employing a high performance liquid chromatography (HPLC) technique for the measurement of sphingomyelin (SP) as well as for the assay of the enzyme sphingomyelinase (SPase) in skin fibroblasts and amniot...

journal_title：Pediatric research

authors： Jungalwala FB,Milunsky A

更新日期：1978-05-01 00:00:00

abstract：:To describe the relation between scalp blood flow and transcutaneous PO2 and PCO2, these three signals were recorded simultaneously in eight experiments on four healthy lambs in the first weeks after birth. Scalp blood flow was recorded by a laser Doppler flow sensor that was incorporated in the transcutaneous PO2 ele...

journal_title：Pediatric research

authors： Smits TM,Aarnoudse JG,Zijlstra WG

更新日期：1990-05-01 00:00:00

abstract：:To examine uridine diphosphate hexose (UDPhexose) content of cells that have more complete metabolic patterns than erythrocytes, which have been commonly used in the study of galactosemia, the concentrations of uridine diphosphate galactose (UDPgalactose) and uridine diphosphate glucose (UDPglucose) were determined in...

journal_title：Pediatric research

authors： Gibson JB,Reynolds RA,Palmieri MJ,States B,Berry GT,Segal S

更新日期：1994-11-01 00:00:00

abstract：:To localize fetal rabbit lung beta-adrenoreceptors before and after glucocorticoid treatment, light microscopic autoradiography was performed with the reversible radiolabeled beta-adrenergic antagonist, [3H]dihydroalprenolol, on day 26 of gestation. Autoradiograms of adult lung and fetal myocardium were also prepared....

journal_title：Pediatric research

authors： Barnes P,Jacobs M,Roberts JM

更新日期：1984-11-01 00:00:00

abstract：:Studies using stable isotopically labeled glucose and palmitate as precursors of pulmonary surfactant synthesis have demonstrated slow surfactant turnover in premature infants with respiratory distress syndrome (RDS). However, only limited data about surfactant turnover are available for term infants. Because acetate ...

journal_title：Pediatric research

authors： Bohlin K,Merchak A,Spence K,Patterson BW,Hamvas A

更新日期：2003-08-01 00:00:00

abstract：:Deficient quantity of amniotic fluid causes fetal guinea pig lung hypoplasia. Oligohydramnios that lasts only 5 days in early gestation is sufficient to reduce fetal lung growth significantly. We quantitated lung structural alterations at 50 days gestation (term is 67 days) of fetal guinea pigs whose amniotic fluid wa...

journal_title：Pediatric research

authors： Collins MH,Moessinger AC,Kleinerman J,James LS,Blanc WA

更新日期：1986-10-01 00:00:00

abstract：:There is significant uncertainty over the role of assessment of long-term neurodevelopmental outcome (LTO) in neonatal clinical trials. A multidisciplinary working group was established to identify key issues in this area and to make recommendations about optimal approaches to evaluate LTO in therapeutic trials in new...

journal_title：Pediatric research

authors： Marlow N,Doyle LW,Anderson P,Johnson S,Bhatt-Mehta V,Natalucci G,Darlow BA,Davis JM,Turner MA,International Neonatal Consortium (INC).

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Using a large population-based sample, this study aims to verify whether televiewing at 29 mo, a common early childhood pastime, is prospectively associated with school readiness at 65 mo. METHODS:Participants are a prospective longitudinal cohort of 991 girls and 1,006 boys from the Quebec Longitudinal Stu...

journal_title：Pediatric research

authors： Pagani LS,Fitzpatrick C,Barnett TA

更新日期：2013-09-01 00:00:00

abstract：:A four-year-old Israeli Arab boy was found to have glycogen accumulation in both liver and muscle without clinical symptoms. Liver phosphorylase kinase (PK) activity was 20% of normal, resulting in undetectable activity of phosphorylase a. Muscle PK activity was about 25% of normal, resulting in a marked decrease of p...

journal_title：Pediatric research

authors： Bashan N,Iancu TC,Lerner A,Fraser D,Potashnik R,Moses SW

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:Short-bowel syndrome (SBS) is the most common cause of neonatal intestinal failure. Recovery requires intestinal adaptation, dependent on enteral nutrition (EN) and growth factors such as glucagon-like peptide-2 (GLP-2), which is secreted from L cells in the ileum. Neonatal SBS often results in loss of ileum...

journal_title：Pediatric research

authors： Hua Z,Turner JM,Sigalet DL,Wizzard PR,Nation PN,Mager DR,Ball RO,Pencharz PB,Wales PW

更新日期：2013-06-01 00:00:00

abstract：:The objective was to investigate any possible relationship between functional and structural vascular changes in women with low gestational age and/or low birth weight by analyzing the retinal vascular pattern in women with thoroughly documented blood pressure. Retinal vessel morphology was evaluated by digital image ...

journal_title：Pediatric research

authors： Kistner A,Jacobson L,Jacobson SH,Svensson E,Hellstrom A

更新日期：2002-06-01 00:00:00

abstract：:The development of amniotic fluid turbidity during the third trimester is a known marker of fetal lung maturity. We hypothesized that this turbidity results from detachment of vernix caseosa from the fetal skin secondary to interaction with pulmonary-derived phospholipids in the amniotic fluid. To test this hypothesis...

journal_title：Pediatric research

authors： Narendran V,Wickett RR,Pickens WL,Hoath SB

更新日期：2000-07-01 00:00:00

abstract：:In neuronal cultures from the forebrain of 14-d-old rat embryos, transient hypoxia (95% N2/5% CO2, 37 degrees C) for 6 h has been shown to trigger delayed apoptotic death through sequential changes in protein synthesis, whereas preconditioning by a brief episode of hypoxia can rescue neurons. Because hypothermia has b...

journal_title：Pediatric research

authors： Bossenmeyer-Pourié C,Koziel V,Daval JL

更新日期：2000-03-01 00:00:00

abstract：:We used an in vitro assay to study and compare the growth-promotional activity of protein and nonprotein components in human milk (HM) and cow milk (CM) samples for infant strains of Bifidobacterium species. HM samples varied considerably in growth-promotion activity for Bifidobacterium bifidum var pennsylvanicus, Bif...

journal_title：Pediatric research

authors： Petschow BW,Talbott RD

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Necrotising enterocolitis (NEC) and late-onset sepsis (LOS) are the leading causes of death among preterm infants in the developed world. This study aimed to explore the serum proteome and metabolome longitudinally in preterm infants with NEC or LOS, matched to controls. METHODS:Nineteen patients (10 cases,...

journal_title：Pediatric research

authors： Stewart CJ,Nelson A,Treumann A,Skeath T,Cummings SP,Embleton ND,Berrington JE

更新日期：2016-03-01 00:00:00

abstract：:To study the effects of cytomegalovirus infection on T-lymphocyte subpopulations, we determined helper (Lyt 1.2) and suppressor (Lyt 2.2) T-lymphocyte subset numbers using monoclonal antibodies and measured lymphocyte responsiveness to mitogen during sublethal murine cytomegalovirus (MCMV) infection of 3-wk-old Balb/c...

journal_title：Pediatric research

authors： Sell MS,Bale JF Jr,Giller RH

更新日期：1985-06-01 00:00:00

abstract：:Four protein dietary groups of rats were used in this study, namely: 27% casein diet fed throughout gestation and lactation (group C-C); 27% gestation, 10% lactation (group C-D); 10% gestation, 27% lactation (group D-C); 10% throughout gestation and lactation (group D-D). Mean body weight of group D-D at warning was 1...

journal_title：Pediatric research

authors： Kissane JQ,Hawrylewicz EJ

更新日期：1975-03-01 00:00:00

abstract：:Our objectives were to establish antecedent factors and patterns of brain injury and their prognostic value in preterm infants with hypoxic-ischemic encephalopathy (HIE). Essential inclusion criteria were gestation (GA) < or =36 wk, Apgar scores <5/<7 at 1/5 min, major resuscitation at birth, and a brain MRI <6 postna...

journal_title：Pediatric research

authors： Logitharajah P,Rutherford MA,Cowan FM

更新日期：2009-08-01 00:00:00

abstract：:We studied chloride efflux from isolated rabbit pancreatic acini in suspension, by loading with 36Cl to steady state and rapidly washing acini by filtration to determine 36Cl cpm/micrograms DNA remaining. Linear loss of acinar chloride occurred over 5 min (k = 0.038 +/- 0.008 min-1, n = 5). Forskolin (5 x 10(-5) M) in...

journal_title：Pediatric research

authors： Kopelman H,Gauthier C

更新日期：1991-06-01 00:00:00

abstract：:We have shown previously that polynucleotides enhance in vitro antibody and Ig production in response to T-dependent antigens in mice and augment Ig production by adult human peripheral blood mononuclear cells. Herein, we report their effects on umbilical cord blood mononuclear cells (CBMNC) obtained from full-term ba...

journal_title：Pediatric research

authors： Jyonouchi H,Zhang-Shanbhag L,Georgieff M,Tomita Y

更新日期：1993-11-01 00:00:00

abstract：:The worldwide burden of disease due to Epstein-Barr virus (EBV) infection is enormous. Diseases include endemic Burkitt lymphoma, infectious mononucleosis, cancers after transplantation, Hodgkin lymphoma, and nasopharyngeal carcinoma. A prophylactic EBV vaccine has the potential to significantly reduce the incidence a...

journal_title：Pediatric research

authors： Balfour HH Jr,Schmeling DO,Grimm-Geris JM

更新日期：2020-01-01 00:00:00

abstract：:Nitric oxide plays a major role in vascular tone control. Increased blood levels of bradykinin (BK), which stimulates nitric oxide biosynthesis, occur at birth. BK effects on ductus arteriosus (DA) tone were investigated in fetal rabbit under fetal (2.5% O2 "low PO2") and neonatal (30% O2 "high PO2") conditions using ...

journal_title：Pediatric research

authors： Bateson EA,Schulz R,Olley PM

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Kawasaki disease (KD) is the most common systemic vasculitis syndrome primarily affecting medium-sized arteries, particularly the coronary arteries. Though KD may be associated with immunological problems, the involvement of microRNAs (miRs) has not been fully described. METHODS:We enrolled 23 KD patients a...

journal_title：Pediatric research

authors： Saito K,Nakaoka H,Takasaki I,Hirono K,Yamamoto S,Kinoshita K,Miyao N,Ibuki K,Ozawa S,Watanabe K,Bowles NE,Ichida F

更新日期：2016-09-01 00:00:00