Scalp blood flow, measured by laser Doppler flowmetry, and transcutaneous PO2 and PCO2 in the lamb.

abstract：:To localize fetal rabbit lung beta-adrenoreceptors before and after glucocorticoid treatment, light microscopic autoradiography was performed with the reversible radiolabeled beta-adrenergic antagonist, [3H]dihydroalprenolol, on day 26 of gestation. Autoradiograms of adult lung and fetal myocardium were also prepared....

journal_title：Pediatric research

authors： Barnes P,Jacobs M,Roberts JM

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Bronchopulmonary dysplasia (BPD) is an important cause of morbidity. The aim of this study was to evaluate the preventive effect of cytidine 5'-diphosphocholine (CDP-choline) treatment on hyperoxic lung injury in a neonatal rat model. METHODS:A total of 30 newborn pups were divided into control, hyperoxia, ...

journal_title：Pediatric research

authors： Cetinkaya M,Cansev M,Kafa IM,Tayman C,Cekmez F,Canpolat FE,Tunc T,Sarici SU

更新日期：2013-07-01 00:00:00

abstract：:Early detection of developmental delay and childhood disorders are important for early intervention. This study aimed to describe the distribution of responses in a large population-based survey, identify cutoff points for the parent concern checklist (PCC) suitable for the Chinese language and culture, and explore ho...

journal_title：Pediatric research

authors： Lung FW,Shu BC,Chiang TL,Lin SJ

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Previous studies indicate an increased risk for neuropsychological difficulties in young children prenatally exposed to opioids and polysubstances, but longitudinal information is scarce. The present longitudinal study investigated whether these waned, persisted, or increased over time. METHODS:The cognitiv...

journal_title：Pediatric research

authors： Nygaard E,Moe V,Slinning K,Walhovd KB

更新日期：2015-09-01 00:00:00

abstract：:The purpose of this investigation was to determine whether maximal oxygen consumption (VO2max) differed between clinically obese black and white children and if a difference existed to determine whether it was related to hematological profiles and/or physical activity/inactivity levels. Twenty-three black and 21 white...

journal_title：Pediatric research

authors： Andreacci JL,Robertson RJ,Dubé JJ,Aaron DJ,Dixon CB,Arslanian SA

更新日期：2005-09-01 00:00:00

abstract：:Concanavalin A surface receptors were detected on brush border enterocytes from child intestinal biopsies by the concanavalin A-peroxidase method. On electron microscopy, these receptors appeared as electron-dense deposits, located on a band running along the innermost part of the brush border membrane glycocalyx. In ...

journal_title：Pediatric research

authors： Vasmant D,Feldmann G,Fontaine JL

更新日期：1982-06-01 00:00:00

abstract：:Heart rate variability (HRV) is reported increasingly in pediatric research, but different strategies used to identify and manage potential outlier beats impact HRV parameter values in adults and animals. Do they in pediatrics? To compare the impact of different strategies to identifying and managing outliers, we used...

journal_title：Pediatric research

authors： Kemper KJ,Hamilton C,Atkinson M

更新日期：2007-09-01 00:00:00

abstract：:Contributions from multidisciplinary investigations have focused attention on the potential of tissue engineering to yield novel therapeutics. Congenital malformations, including cleft palate, craniosynostosis, and craniofacial skeletal hypoplasias represent excellent targets for the implementation of tissue engineeri...

journal_title：Pediatric research

authors： Panetta NJ,Gupta DM,Slater BJ,Kwan MD,Liu KJ,Longaker MT

更新日期：2008-05-01 00:00:00

abstract：:Heart rate turbulence (HRT) is a chronotropic response of the sinus heart rhythm to ventricular premature beat (VPB). Children show decreasing heart rate together with the maturation of the autonomic nervous system. The aim of the research was to assess the relationship between HRT parameters, age, and heart rate and ...

journal_title：Pediatric research

authors： Kowalewski M,Alifier M,Bochen D,Urban M

更新日期：2007-12-01 00:00:00

abstract：:BackroundMicrocephaly can either be isolated or it may coexist with other neurological entities and/or multiple congenital anomalies, known as syndromic microcephaly. Although many syndromic cases can be classified based on the characteristic phenotype, some others remain uncertain and require further investigation. T...

journal_title：Pediatric research

authors： Tsoutsou E,Tzetis M,Giannikou K,Braoudaki M,Mitrakos A,Amenta S,Selenti N,Kanavakis E,Zafeiriou D,Kitsiou-Tzeli S,Fryssira H

更新日期：2017-08-01 00:00:00

abstract：:A prospective study to define the normal patterns of development of mucosal immunity in 263 children provided a unique opportunity to study the mucosal immune response in an infant who unexpectedly died from sudden infant death syndrome. The subject initially had a normal pattern of mucosal immune function, which was ...

journal_title：Pediatric research

authors： Gleeson M,Clancy RL,Cripps AW

更新日期：1993-06-01 00:00:00

abstract：:Hypothermia is a frequent occurrence in newborns, and thermoregulatory management is a fundamental part of medical stabilization. Although modest reduction in brain temperature (2-3 degrees C) before ischemia provides neuroprotection in adults, the effect of modest hypothermia on immature brain has not been examined. ...

journal_title：Pediatric research

authors： Laptook AR,Corbett RJ,Sterett R,Burns DK,Tollefsbol G,Garcia D

更新日期：1994-04-01 00:00:00

abstract：:We studied the effects of exogenously administered adrenomedullin on fetal pulmonary arterial blood flow in near-term fetal sheep. The hemodynamic effects of a single injection of adrenomedullin into the left pulmonary artery were compared with those of acetylcholine; the effects of repeated injections of adrenomedull...

journal_title：Pediatric research

authors： de Vroomen M,Takahashi Y,Gournay V,Roman C,Rudolph AM,Heymann MA

更新日期：1997-04-01 00:00:00

abstract：:Docosahexaenoic acid (DHA) is an omega-3 fatty acid that is highly concentrated in CNS tissues. Although breast milk contains the fatty acids DHA and arachidonic acid, infant formulas marketed in North America do not contain these nutrients. The potential deleterious effects of rearing infants with formulas devoid of ...

journal_title：Pediatric research

authors： Champoux M,Hibbeln JR,Shannon C,Majchrzak S,Suomi SJ,Salem N Jr,Higley JD

更新日期：2002-03-01 00:00:00

abstract：:Clinical studies have suggested that the early stages of bilirubin encephalopathy are reversible. These phenomena are investigated at the cellular level using the neuroblastoma cell line N-115 as a model system. To determine whether the cell line N-115 can recover from bilirubin toxicity, and whether the cellular func...

journal_title：Pediatric research

authors： Amit Y,Poznansky MJ,Schiff D

更新日期：1989-04-01 00:00:00

abstract：:This study was carried out to determine the influence and site of action of N omega-nitro-L-arginine methylester, an L-arginine analogue, on basal pulmonary vascular tone and hypoxic vasoconstriction in neonatal pig lungs. We studied isolated lungs from pigs, age 14.5 +/- 0.5 (SD) d and weight 3.6 +/- 0.7 kg, perfused...

journal_title：Pediatric research

authors： Nelin LD,Dawson CA

更新日期：1993-09-01 00:00:00

abstract：:To determine the influence of an altered carotid body function on the laryngeal chemoreflex (LCR) response, reflex apnea was induced by laryngeal water stimulation during normoxia or acute hypoxia in unanesthetized awake lambs in which the ventilatory response to acute hypoxia was attenuated by prolonged postnatal hyp...

journal_title：Pediatric research

authors： Sladek M,Grogaard JB,Parker RA,Sundell HW

更新日期：1993-12-01 00:00:00

abstract：:Leukotriene B4 (LTB4) is a product of arachidonic acid metabolism and a potent chemoattractant for adult polymorphonuclear leukocytes (PMN). LTB4 may be an important inflammatory mediator in neonatal lung disorders such as bronchopulmonary dysplasia, but neonatal PMN chemotaxis to LTB4 has not been studied. We compare...

journal_title：Pediatric research

authors： Dos Santos C,Davidson D

更新日期：1993-03-01 00:00:00

abstract：:The relationship between the development of cytotoxic cellular immune response to herpes simplex virus type I (HSV-1)-infected autologous cells and the production of interferon (IFN) was studied using in vitro secondary sensitization of peripheral blood leukocytes in subjects with recurrent herpes labialis (RHL) and i...

journal_title：Pediatric research

authors： Tsutsumi H,Bernstein JM,Riepenhoff-Talty M,Ogra PL

更新日期：1986-09-01 00:00:00

abstract：:The perinatal ontogeny of preprotachykinin-A gene expression was assessed in central respiration-related structures. On the day of birth, there was an enhanced expression of preprotachykinin-A mRNA in the region of the nucleus tractus solitarii, the primary relay station for respiratory and cardiovascular reflexes. Th...

journal_title：Pediatric research

authors： Srinivasan M,Yamamoto Y,Persson H,Lagercrantz H

更新日期：1991-04-01 00:00:00

abstract：:Acute kidney injury (AKI) is common in premature infants and is associated with poor outcomes. Novel biomarkers can detect AKI promptly. Because premature infants are born with underdeveloped kidneys, baseline biomarker values may differ. We describe baseline values of urinary neutrophil gelatinase-associated lipocali...

journal_title：Pediatric research

authors： Askenazi DJ,Koralkar R,Levitan EB,Goldstein SL,Devarajan P,Khandrika S,Mehta RL,Ambalavanan N

更新日期：2011-09-01 00:00:00

abstract：:Clinical trials demonstrated decreasing rates of bronchopulmonary dysplasia in preterm infants with hypoxic respiratory failure treated with inhaled nitric oxide (iNO). However, the molecular and biochemical effects of iNO on developing human fetal lungs remain vastly unknown. By using a well-characterized model of hu...

journal_title：Pediatric research

authors： Johnston LC,Gonzales LW,Lightfoot RT,Guttentag SH,Ischiropoulos H

更新日期：2010-05-01 00:00:00

abstract：:An increase in polymorphonuclear leukocytes (PMNs) and proinflammatory chemokines, such as IL-8 and macrophage inflammatory protein-1 alpha (MIP), are found in the airways during early stages of bronchopulmonary dysplasia. We determined whether IL-10 produces a dose-related inhibition of proinflammatory chemokine rele...

journal_title：Pediatric research

authors： Tryzmel J,Miskolci V,Castro-Alcaraz S,Vancurova I,Davidson D

更新日期：2003-09-01 00:00:00

abstract：:To assess the National Institutes of Health extramural activity in the area of pediatric nephrology research, the rate of submission of grant applications to the National Institutes of Health and available indicators of the quality of these applications were analyzed. This was accomplished by utilizing the grant appli...

journal_title：Pediatric research

authors： Novello AC

更新日期：1985-11-01 00:00:00

abstract：:We have previously discovered that the adult Drosophila melanogaster is tolerant to a low O2 environment, withstanding hours of total O2 deprivation without showing any evidence of cell injury. Subsequently, our laboratory embarked on the study of hypoxia tolerance using a mutagenesis and overexpression screens to beg...

journal_title：Pediatric research

authors： Zhou D,Visk DW,Haddad GG

更新日期：2009-09-01 00:00:00

abstract：:Television viewing (TVV) is considered a contributing factor to the development of childhood obesity yet it is unclear whether obesity results, in part, from increased energy intake during TVV. The objective of this study was to determine the effect of TVV on food intake (FI) of boys at a meal and its effect on calori...

journal_title：Pediatric research

authors： Bellissimo N,Pencharz PB,Thomas SG,Anderson GH

更新日期：2007-06-01 00:00:00

abstract：:Recombinant human erythropoietin (rEpo) is neuroprotective in neonatal models of hypoxic-ischemic brain injury. However, the optimal rEpo dose, dosing interval, and number of doses for reducing brain injury are still undetermined. We compared the neuroprotective efficacy of several subcutaneous rEpo treatment regimens...

journal_title：Pediatric research

authors： Kellert BA,McPherson RJ,Juul SE

更新日期：2007-04-01 00:00:00

abstract：:Chitosan is a natural, cationic polysaccharide derived from fully or partially deacetylated chitin. Chitosan is capable of inducing large phospholipid aggregates, closely resembling the function of nonionic polymers tested previously as additives to therapeutic lung surfactants. The effects of chitosan on improving th...

journal_title：Pediatric research

authors： Zuo YY,Alolabi H,Shafiei A,Kang N,Policova Z,Cox PN,Acosta E,Hair ML,Neumann AW

更新日期：2006-08-01 00:00:00

abstract：:Late Onset Central Hypoventilation Syndrome associated with Hypothalamic Dysfunction (LO-CHS/HD) is a distinct entity among the clinical and genetic heterogeneous group of patients with late onset central hypoventilation. Here we report a series of 13 patients with LO-CHS/HD. Rapid onset obesity is the first symptom o...

journal_title：Pediatric research

authors： De Pontual L,Trochet D,Caillat-Zucman S,Abou Shenab OA,Bougneres P,Crow Y,Cunningham S,Esteva B,Heberle LC,Leger J,Pinto G,Polak M,Shafik MH,Straus C,Trang H,Munnich A,Lyonnet S,Desguerre I,Amiel J

更新日期：2008-12-01 00:00:00

abstract：:Pearson's syndrome, a rare and fatal disorder characterized by refractory sideroblastic anemia and pancreatic insufficiency in infancy, is classified into mitochondrial cytopathies. To understand the molecular and genetic bases of this disorder, we have investigated the mitochondrial respiratory chain enzymes and the ...

journal_title：Pediatric research

authors： Sano T,Ban K,Ichiki T,Kobayashi M,Tanaka M,Ohno K,Ozawa T

更新日期：1993-07-01 00:00:00