Abstract:
:Heart rate variability (HRV) is reported increasingly in pediatric research, but different strategies used to identify and manage potential outlier beats impact HRV parameter values in adults and animals. Do they in pediatrics? To compare the impact of different strategies to identifying and managing outliers, we used interbeat interval (IBI) data from three different populations: 10 stable premature infants, 33 stable pediatric oncology patients, and 15 healthy adults. Five commonly reported HRV parameters were compared using three identification and two management strategies to filter potential outliers. The three populations had different resting heart rates: 155 +/- 9 beats per minute (bpm) in infants, 105 +/- 17 bpm in children, and 87 +/- 12 bpm in adults. All three identification strategies flagged fewer than 2% of IBIs; the threshold identification strategy, excluding IBIs denoting heart rates <30 or >300 bpm, identified significantly fewer outliers than the other two strategies and generated higher HRV parameters in all populations (p < 0.001). There were no significant differences in HRV parameters calculated by managing identified outliers by "tossing" them versus "interpolating" values. Different strategies for identifying potential outliers are associated with significant differences in HRV parameters. Pediatric researchers who report HRV should detail their outlier filtering strategies.
journal_name
Pediatr Resjournal_title
Pediatric researchauthors
Kemper KJ,Hamilton C,Atkinson Mdoi
10.1203/PDR.0b013e318123fbccsubject
Has Abstractpub_date
2007-09-01 00:00:00pages
337-42issue
3eissn
0031-3998issn
1530-0447journal_volume
62pub_type
杂志文章abstract::Spring steel coils have been used to occlude abnormal vessels in patients with a congenital heart malformation. However, long-term adverse effects of steel spring coils remain uncertain, although some long-term results appear to be good. The purpose of this study was to evaluate the angiographic and histologic results...
journal_title:Pediatric research
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doi:10.1203/00006450-199804000-00016
更新日期:1998-04-01 00:00:00
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journal_title:Pediatric research
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journal_title:Pediatric research
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journal_title:Pediatric research
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abstract::Insulin treatment of prepubertal children with insulin-dependent diabetes improves body protein balance by decreasing the rate of protein degradation without stimulating protein synthesis. However, insulin also causes hypoaminoacidemia, so the inability of insulin to stimulate protein synthesis may have been limited b...
journal_title:Pediatric research
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journal_title:Pediatric research
pub_type: 杂志文章,评审
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更新日期:2015-01-01 00:00:00
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更新日期:2016-03-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
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更新日期:1980-02-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
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更新日期:2013-03-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1038/s41390-019-0560-z
更新日期:2020-03-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1203/00006450-199905010-00008
更新日期:1999-05-01 00:00:00
abstract::Intrahepatic and intracerebral metabolic responses to neonatal fasting or enteric carbohydrate alimentation were investigated among newborn dogs. Pups were either fasted or given an intravenous glucose infusion (alimented) before an enteric feeding of physiologic quantities of either glucose or galactose. These pups w...
journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1203/00006450-198304000-00012
更新日期:1983-04-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1203/00006450-197609000-00002
更新日期:1976-09-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1038/pr.2013.212
更新日期:2014-02-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1203/00006450-198412000-00010
更新日期:1984-12-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1203/00006450-199106010-00006
更新日期:1991-06-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1203/00006450-198105000-00008
更新日期:1981-05-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1203/PDR.0b013e3181a1fb3d
更新日期:2009-07-01 00:00:00
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更新日期:2004-07-01 00:00:00
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更新日期:1978-08-01 00:00:00
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doi:10.1203/00006450-199712000-00013
更新日期:1997-12-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章,评审
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更新日期:2011-05-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
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更新日期:1981-09-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2004-12-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
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更新日期:1996-01-01 00:00:00
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journal_title:Pediatric research
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更新日期:1987-09-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1203/00006450-199804000-00006
更新日期:1998-04-01 00:00:00
abstract::The primary manifestations of Pompe disease are muscle weakness and cardiomyopathy. Although accumulation of glycogen has also been seen in the nervous system in patients, the significance of brain involvement in infantile-onset Pompe disease is not clear. In this study, brain development in five cases of infantile-on...
journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1203/01.pdr.0000233014.84318.4e
更新日期:2006-09-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1038/s41390-019-0724-x
更新日期:2020-06-01 00:00:00