Effect of racemic epinephrine on ventilatory function in the neonate postextubation.

abstract：:Sleep organization of infants may be influenced by differences in nutrient intakes from human milk and formula. Because sleep/awake and sleep stage patterns affect energy expenditure, we hypothesized that differences in sleep organization between breast-fed and formula-fed infants might account in part for differences...

journal_title：Pediatric research

authors： Butte NF,Jensen CL,Moon JK,Glaze DG,Frost JD Jr

更新日期：1992-11-01 00:00:00

abstract：:Ventilation of immature airways has been shown to result in pressure-induced deformation and alteration of mechanical properties. These changes in mechanical properties may alter the effect of compressive pressures on pressure-flow relationships. To test this hypothesis, unventilated (Group I, n = 8) and ventilated (g...

journal_title：Pediatric research

authors： Penn RB,Wolfson MR,Shaffer TH

更新日期：1988-05-01 00:00:00

abstract：:Television viewing (TVV) is considered a contributing factor to the development of childhood obesity yet it is unclear whether obesity results, in part, from increased energy intake during TVV. The objective of this study was to determine the effect of TVV on food intake (FI) of boys at a meal and its effect on calori...

journal_title：Pediatric research

authors： Bellissimo N,Pencharz PB,Thomas SG,Anderson GH

更新日期：2007-06-01 00:00:00

abstract：:The mitochondria play a major role in the regulation of intracellular calcium. Despite the fact that the enterocytes receive the majority of absorbed calcium, the role of the intestinal mitochondria in calcium transport during maturation is not known. Therefore, the current studies were designed to characterize calciu...

journal_title：Pediatric research

authors： Kikuchi T,Kikuchi K,Arab N,Ghishan FK

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Animal models have shown that insulin-like growth factor I (IGF-I) may mediate protein-induced kidney growth. Our aim was to analyze the effect of IGF-I on protein-induced kidney growth in healthy infants. METHODS:This is a secondary analysis of a randomized trial that compared growth of infants fed with a ...

journal_title：Pediatric research

authors： Luque V,Escribano J,Grote V,Ferre N,Koletzko B,Gruszfeld D,Socha P,Langhendries JP,Goyens P,Closa-Monasterolo R,European Childhood Obesity Project.

更新日期：2013-08-01 00:00:00

abstract：:Early-onset neonatal group B beta-hemolytic streptococcus (GBS) infection exhibits pathophysiologic characteristics of a toxic shock syndrome, in which a cascade of inflammatory mediators are involved. Thromboxane A2 (TXA2) is thought to play an important role as a mediator of the pulmonary response to GBS toxin, beca...

journal_title：Pediatric research

authors： Sandberg K,Edberg KE,Fish W,Parker RA,Hellerqvist C,Sundell H

更新日期：1994-05-01 00:00:00

abstract：:Defective arousal mechanisms are viewed as contributory to sleep hypopnea disorders and sudden infant death syndrome. Sighs (i.e. augmented breaths) as well as startles have not traditionally been viewed as arousal-related phenomena in infants. We hypothesized that, if sighs and startles are the initial event in a seq...

journal_title：Pediatric research

authors： Wulbrand H,McNamara F,Thach BT

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:The pathogenesis of BPD includes inflammation and oxidative stress in the immature lung. Corticosteroids improve respiratory status and outcome, but the optimal treatment regimen for benefit with low systemic effects is uncertain. METHODS:In a pilot dose escalation trial, we administered ≤5 daily doses of b...

journal_title：Pediatric research

authors： Ballard PL,Torgerson D,Wadhawan R,Hudak ML,Weitkamp JH,Harris J,Asselin J,Chapin C,Ballard RA,McEvoy CT

更新日期：2021-01-19 00:00:00

abstract：:DGCR6 is the most centromeric gene in the human DiGeorge critical region and is the only gene in the region with a second functional copy on a repeat localized more distally on chromosome 22. We isolated the chicken ortholog of DGCR6 and showed an embryonic expression pattern that is initially broad but becomes gradua...

journal_title：Pediatric research

authors： Hierck BP,Molin DG,Boot MJ,Poelmann RE,Gittenberger-de Groot AC

更新日期：2004-09-01 00:00:00

abstract：:L-selectin, a surface adhesion glycoprotein expressed on leukocytes, has a well-established role in mediating inflammation and lymphocyte recirculation. Recent evidence suggests that L-selectin may also influence hematopoiesis. We observed that a greater proportion of CD34+ cells express L-selectin in cord blood compa...

journal_title：Pediatric research

authors： Koenig JM,Baron S,Luo D,Benson NA,Deisseroth AB

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Angiotensin (ANG) II is involved in experimental hyperoxia-induced lung fibrosis. Angiotensin-converting enzyme-2 (ACE-2) degrades ANG II and is thus protective, but is downregulated in adult human and experimental lung fibrosis. Hyperoxia is a known cause of chronic fibrotic lung disease in neonates, but th...

journal_title：Pediatric research

authors： Oarhe CI,Dang V,Dang M,Nguyen H,Gopallawa I,Gewolb IH,Uhal BD

更新日期：2015-05-01 00:00:00

abstract：:It has been shown that glucocorticoids accelerate lung development by limiting alveolar formation resulting from a premature maturation of the alveolar septa. Based on these data, the aim of the present work was to analyze the influence of dexamethasone on cell cycle control mechanisms during postnatal lung developmen...

journal_title：Pediatric research

authors： Corroyer S,Schittny JC,Djonov V,Burri PH,Clement A

更新日期：2002-02-01 00:00:00

abstract：:Gitelman disease was diagnosed in two unrelated children with hypokalemic metabolic alkalosis and growth failure (a boy and a girl aged 7 mo and 9.5 y, respectively, at clinical presentation) on the basis of mutations detected in the gene encoding the thiazide-sensitive NaCl cotransporter of the distal convoluted tubu...

journal_title：Pediatric research

authors： Bettinelli A,Rusconi R,Ciarmatori S,Righini V,Zammarchi E,Donati MA,Isimbaldi C,Bevilacqua M,Cesareo L,Tedeschi S,Garavaglia R,Casari G

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Irisin is a myokine secreted by skeletal muscle during physical activity. Irisin treatment increased cortical bone mineral density (BMD) in young healthy mice and restored bone and muscle mass loss in a mouse model of disuse-induced osteoporosis and muscular atrophy. In humans, Irisin was positively correlat...

journal_title：Pediatric research

authors： Colaianni G,Faienza MF,Sanesi L,Brunetti G,Pignataro P,Lippo L,Bortolotti S,Storlino G,Piacente L,D'Amato G,Colucci S,Grano M

更新日期：2019-03-01 00:00:00

abstract：:Epidermal growth factor (EGF) and transforming growth factor-alpha (TGF-alpha) are mitogenic to the intestinal epithelium. To further clarify their role in the developing human fetal gut, their expression was studied in fetuses at 15 to 20 wk of gestation. TGF-alpha mRNA was present throughout the gastrointestinal tra...

journal_title：Pediatric research

authors： Miettinen PJ

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Prolonged hypoglycemia leads to brain injury, despite treatment with 10% dextrose. Whether induction of hyperglycemia or ketonemia achieves better neuroprotection is unknown. Hyperglycemia is neuroprotective in other brain injuries during development; however, it worsens hypoglycemia-induced injury in the ad...

journal_title：Pediatric research

authors： Ennis K,Dotterman H,Stein A,Rao R

更新日期：2015-01-01 00:00:00

abstract：:Branching morphogenesis, defined as growth and branching of epithelial tubules during embryogenesis, is a fundamental feature of renal, lung, mammary gland, submandibular gland, and pancreatic morphogenesis in mammals. Disruption of branching morphogenesis has been demonstrated to result in maldevelopment of some of t...

journal_title：Pediatric research

authors： Hu MC,Rosenblum ND

更新日期：2003-10-01 00:00:00

abstract：:The regionalization of pediatric services has resulted in differential access to care, sometimes creating barriers to those living in underserved, rural communities. These disparities in access contribute to inferior healthcare outcomes among infants and children. We review the medical literature on telemedicine and i...

journal_title：Pediatric research

authors： Marcin JP,Shaikh U,Steinhorn RH

更新日期：2016-01-01 00:00:00

abstract：:Data are scant regarding the development of cerebrovascular autoregulation in intrauterine growth-restricted (IUGR) newborns. We tested the hypothesis that IUGR improves the ability of neonates to withstand critical periods of gradual hemorrhagic hypotension by optimizing cerebrovascular autoregulation. Studies were c...

journal_title：Pediatric research

authors： Bauer R,Walter B,Vollandt R,Zwiener U

更新日期：2004-10-01 00:00:00

abstract：:To determine the importance of peroxisomes and mitochondria in hydroxyeicosatetraenoic acid (HETE) oxidation in vivo, urinary excretion of 12- and 15-HETE was measured in eight patients with a peroxisome deficiency disorder (Zellweger syndrome) showing normal mitochondrial beta-oxidation capacity, in three patients wi...

journal_title：Pediatric research

authors： Mayatepek E,Lehmann WD

更新日期：1996-01-01 00:00:00

abstract：:There is great interest in the regenerative potential of the neural stem cells and progenitors that populate the germinal zones of the immature brain. Studies using animal models of pediatric brain injuries have provided a clearer understanding of the responses of these progenitors to injury. In this review, we have c...

journal_title：Pediatric research

authors： Niimi Y,Levison SW

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Secreted frizzled-related protein 5 (SFRP5) is an adipokine protecting against obesity-related insulin resistance and diabetes. SFRP5 binds to wingless type mouse mammary tumor virus (MMTV) integration site family member 5A (WNT5A) to improve insulin sensitivity. We performed the first study of SFRP5 and WNT...

journal_title：Pediatric research

authors： Prats-Puig A,Soriano-Rodríguez P,Carreras-Badosa G,Riera-Pérez E,Ros-Miquel M,Gomila-Borja A,de Zegher F,Ibáñez L,Bassols J,López-Bermejo A

更新日期：2014-06-01 00:00:00

abstract：:To examine uridine diphosphate hexose (UDPhexose) content of cells that have more complete metabolic patterns than erythrocytes, which have been commonly used in the study of galactosemia, the concentrations of uridine diphosphate galactose (UDPgalactose) and uridine diphosphate glucose (UDPglucose) were determined in...

journal_title：Pediatric research

authors： Gibson JB,Reynolds RA,Palmieri MJ,States B,Berry GT,Segal S

更新日期：1994-11-01 00:00:00

abstract：:There is increasing evidence that cortisol contributes to cardiovascular risk. It is unclear whether physiological concentrations of serum cortisol are related to vascular risk markers in children. The cross-sectional associations between morning serum cortisol and cardiovascular risk markers: blood pressure (BP) and ...

journal_title：Pediatric research

authors： Soriano-Rodríguez P,Osiniri I,Grau-Cabrera P,Riera-Pérez E,Prats-Puig A,Carbonell-Alferez M,Schneider S,Mora-Maruny C,De Zegher F,Ibánez L,Bassols J,López-Bermejo A

更新日期：2010-11-01 00:00:00

abstract：:Medium chain acyl-CoA dehydrogenase deficiency (MCAD) is a defect in the mitochondrial oxidation of fatty acids. The disorder typically presents with episodes of vomiting and hypoglycemia, sometimes with changes in mental status and hepatic failure. These Reye's-like features may culminate in coma and death. Stress, i...

journal_title：Pediatric research

authors： Ziadeh R,Hoffman EP,Finegold DN,Hoop RC,Brackett JC,Strauss AW,Naylor EW

更新日期：1995-05-01 00:00:00

abstract：:Argininosuccinate synthetase and argininosuccinate lyase catalyze the conversion of citrulline to arginine in kidney. Immunohistochemical staining of mouse kidney sections with antibodies to these two enzymes, compared with the staining patterns of known markers for proximal tubules, demonstrated that these enzymes ar...

journal_title：Pediatric research

authors： Morris SM Jr,Sweeney WE Jr,Kepka DM,O'Brien WE,Avner ED

更新日期：1991-02-01 00:00:00

abstract：:The effect of alpha-adrenergic blockade by phentolamine on the pulmonary vascular response to dopamine was studied in chronically prepared newborn lambs. Dopamine was administered at doses of 2.7 micrograms . kg-1 . min-1, 27 micrograms . kg-1 . min-1 and 270 micrograms . kg-1 . min-1 with and without alpha-adrenergic...

journal_title：Pediatric research

authors： Williams BJ,Drummond WH

更新日期：1983-06-01 00:00:00

abstract：UNLABELLED:The hGH response to an ornithin or an insulin test was measured in 105 children from 11-18 yr old with delay of growth more than 2 SD. Besides 74 subjects with normal values and 7 with complete lack of response, 24 subjects exhibited a partial rise of GH. Most of the latter had decreasing growth rate and no ...

journal_title：Pediatric research

authors： Gourmelen M,Pham-Huu-Trung MT,Girard F

更新日期：1979-04-01 00:00:00

abstract：:Pearson's syndrome, a rare and fatal disorder characterized by refractory sideroblastic anemia and pancreatic insufficiency in infancy, is classified into mitochondrial cytopathies. To understand the molecular and genetic bases of this disorder, we have investigated the mitochondrial respiratory chain enzymes and the ...

journal_title：Pediatric research

authors： Sano T,Ban K,Ichiki T,Kobayashi M,Tanaka M,Ohno K,Ozawa T

更新日期：1993-07-01 00:00:00

abstract：:Mucosal samples from rabbit jejunum were incubated (30 min, 25 degrees C) with (125I)glycinin in the presence of buffer, soybean lectin (50 micrograms/ml) soyasaponins (1 mg/ml), or both lectin and saponins. The mucosal uptake of (125I)glycinin was negligible with buffer, and increased progressively with additions of ...

journal_title：Pediatric research

authors： Alvarez JR,Torres-Pinedo R

更新日期：1982-09-01 00:00:00