L-selectin expression enhances clonogenesis of CD34+ cord blood progenitors.

abstract：:BackgroundPoor aerobic fitness is associated with worsening of asthma symptoms, and fitness training may improve asthma control. The mechanism linking fitness with asthma is not known. We hypothesized that repeated bouts of exercise would lead to a downregulation of glucocorticoid receptor (GR) expression on circulati...

journal_title：Pediatric research

authors： Lu KD,Cooper D,Haddad F,Zaldivar F,Kraft M,Radom-Aizik S

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Preterm infants have a greater risk of necrotizing enterocolitis following transfusion. It is hypothesized that high glucose concentrations in red blood cell (RBC) preservatives lead to increased methylglyoxal (MG) metabolism, causing glycation-driven damage to transfused RBCs. Such changes to the RBCs could...

journal_title：Pediatric research

authors： Kiefer AS,Fleming T,Eckert GJ,Poindexter BB,Nawroth PP,Yoder MC

更新日期：2014-03-01 00:00:00

abstract：:Neonatal hypoxic-ischemic encephalopathy (HIE) is a clinically defined neurological condition after lack of oxygen and often associated with cardiac dysfunction in term infants. Therapeutic hypothermia (HT) after birth is neuroprotective in infants with HIE. However, it is not known whether HT is also cardioprotective...

journal_title：Pediatric research

authors： Liu X,Tooley J,Løberg EM,Suleiman MS,Thoresen M

更新日期：2011-10-01 00:00:00

abstract：:A series of in vivo experiments is described in which [1-13C]phytanic acid was given as an oral substrate to a healthy subject and two patients showing an impairment in phytanic acid degradation, one with Refsum's disease and one with chondrodysplasia punctata. After intake of the substrate by the control in a dose of...

journal_title：Pediatric research

authors： ten Brink HJ,Schor DS,Kok RM,Stellaard F,Kneer J,Poll-The BT,Saudubray JM,Jakobs C

更新日期：1992-11-01 00:00:00

abstract：:Bilirubin-IX alpha photooxidation products were detected by high performance liquid chromatography in the urine of neonates undergoing phototherapy for hyperbilirubinemia. The in vivo photoproducts were identified by chromatographic comparison with authentic synthetic standards using two complementary methods. Bilirub...

journal_title：Pediatric research

authors： Lightner DA,Linnane WP 3rd,Ahlfors CE

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:Scoring tools used to quantify withdrawal in infants with neonatal abstinence syndrome (NAS) are often confounded by subjective measurements. This study assessed salivary cortisol as an objective biomarker of withdrawal severity in opioid-exposed newborns. METHODS:A prospective study was conducted in 25 ful...

journal_title：Pediatric research

authors： Rodriguez N,Vining M,Bloch-Salisbury E

更新日期：2020-05-01 00:00:00

abstract：:The role of nitric oxide (NO) as well as its interaction with prostaglandins (PG) in setting the limits of autoregulation of retinal blood flow (RBF) and choroidal blood flow (ChBF) were studied in newborn pigs (1-5 d old). Blood flows were measured by the microsphere technique. Low and high ocular perfusion pressures...

journal_title：Pediatric research

authors： Hardy P,Nuyt AM,Abran D,St-Louis J,Varma DR,Chemtob S

更新日期：1996-03-01 00:00:00

abstract：:Our objectives were to establish antecedent factors and patterns of brain injury and their prognostic value in preterm infants with hypoxic-ischemic encephalopathy (HIE). Essential inclusion criteria were gestation (GA) < or =36 wk, Apgar scores <5/<7 at 1/5 min, major resuscitation at birth, and a brain MRI <6 postna...

journal_title：Pediatric research

authors： Logitharajah P,Rutherford MA,Cowan FM

更新日期：2009-08-01 00:00:00

abstract：:In Krabbe's disease (globoid cell leukodystrophy), galactosylsphingosine (psychosine) is considered to be a causative agent of the pathology found in the nervous system of the patients. In our study, we examined the cytotoxic effect of psychosine in neural cell cultures derived from the rat nervous system. The concent...

journal_title：Pediatric research

authors： Sugama S,Kim SU,Ida H,Eto Y

更新日期：1990-11-01 00:00:00

abstract：:Although tyrosine is considered indispensable during the neonatal period, its poor solubility has limited its inclusion in parenteral amino acid solutions to less than 1% of total amino acids. Dipeptides of tyrosine are highly soluble, have been shown to be well used and safe in animal models and humans, and, therefor...

journal_title：Pediatric research

authors： Roberts SA,Ball RO,Moore AM,Filler RM,Pencharz PB

更新日期：2001-01-01 00:00:00

abstract：:Ambulatory blood pressure (ABP) monitoring offers a reliable method for determining blood pressure (BP) in children. The aim of this cohort study was to examine whether maternal preeclampsia is associated with elevated BP in an offspring. The study population consisted of 57 children born to preeclamptic mothers (PRE)...

journal_title：Pediatric research

authors： Tenhola S,Rahiala E,Halonen P,Vanninen E,Voutilainen R

更新日期：2006-02-01 00:00:00

abstract：:Stimulation of cutaneous thermoreceptors may be an important factor in the initiation of continuous breathing at birth. Maintenance of a patent airway is also important in the continuation of effective ventilation after birth, but whereas in the adult the principal pharyngeal dilator is the genioglossus muscle, in the...

journal_title：Pediatric research

authors： Johnston BM,Gunn TR,Gluckman PD

更新日期：1988-03-01 00:00:00

abstract：INTRODUCTION:Corticosteroids have been widely used in clinical medicine as a first-line therapy to modify the inflammatory response in many pulmonary and systemic diseases. Inhaled and intratracheally administered corticosteroids have a particular interest in that their use allows the clinician to circumvent systemic s...

journal_title：Pediatric research

authors： Zhang H,Wang YE,Neal CR,Zuo YY

更新日期：2012-04-01 00:00:00

abstract：:We studied properties of saliva and of dental plaque which affect the caries process in an effort to understand the low prevalence of caries in patients with chronic renal failure. Plaque pH, before and following carbohydrate exposure, saliva pH, and saliva composition were evaluated in children and adolescents with c...

journal_title：Pediatric research

authors： Peterson S,Woodhead J,Crall J

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Short forms of IQ (S-IQ) assessments are time efficient and highly predictive of the full IQ (F-IQ) in healthy individuals. To investigate the validity of S-IQs for patients with neurodevelopmental impairments, this study tested a well-established S-IQ version in patients with congenital heart disease (CHD)....

journal_title：Pediatric research

authors： Ehrler M,Latal B,Polentarutti S,von Rhein M,Held L,Wehrle FM

更新日期：2020-04-01 00:00:00

abstract：:Permeability of the blood brain barrier (BBB) for bilirubin and 125I-albumin was studied in 2-d- and 2-wk-old piglets. 125I-albumin was given by bolus at the beginning of each study. Hyperbilirubinemia was produced by an initial bolus infusion of bilirubin and sustained at a plasma bilirubin:albumin molar ratio of app...

journal_title：Pediatric research

authors： Lee C,Oh W,Stonestreet BS,Cashore WJ

更新日期：1989-05-01 00:00:00

abstract：:Fetal growth and development is dependent on the transfer of amino acids from maternal to fetal blood across the microvillous plasma membrane (MVM) and basal plasma membrane of placental syncytiotrophoblast. The aim of this study was to determine the relationship of system A amino acid transporter (SysA) activity in M...

journal_title：Pediatric research

authors： Harrington B,Glazier J,D'Souza S,Sibley C

更新日期：1999-06-01 00:00:00

abstract：:Simultaneous measurements of serum immunoreactive thyrocalcitonin (iTCT), immunoreactive parathyroid hormone (iPTH), calcium, inorganic phosphate, magnesium, and alkaline phosphatase were made in 37 normal children whose ages ranged from 6-12 years. Between the ages of 6 and 12 there is a statistically significant ris...

journal_title：Pediatric research

authors： Shainkin-Kerstenbaum R,Funkenstein B,Conforti A,Shani S,Berlyne GM

更新日期：1977-02-01 00:00:00

abstract：:The ability of erythrocytes from newborn babies and adults to maintain reduced glutathione levels during oxidative stress was studied. In vitro incubation of erythrocytes with H2O2, with or without inactivation of catalase, caused a rapid depletion of reduced glutathione (GSH) and concomitant accumulation of oxidized ...

journal_title：Pediatric research

authors： Clahsen PC,Moison RM,Holtzer CA,Berger HM

更新日期：1992-10-01 00:00:00

abstract：:In mice, secondary alveolar septal formation primarily occurs during a brief postnatal period and is accompanied by transient expansion of the interstitial lung fibroblast (LF) population. PDGF-A, which solely signals through PDGF-receptor-alpha (PDGF-Rα), is required for expansion, but the receptor's relevant downstr...

journal_title：Pediatric research

authors： McGowan SE,McCoy DM

更新日期：2011-07-01 00:00:00

abstract：:Serial plasma concentrations of immunoreactive 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), the stable hydration product of prostacyclin (PGI2), were measured with radioimmunoassay during the first month of life in 25 preterm infants with idiopathic respiratory distress syndrome (IRDS) and 38 preterm controls wi...

journal_title：Pediatric research

authors： Kääpä P,Koivisto M,Viinikka L,Ylikorkala O

更新日期：1982-10-01 00:00:00

abstract：:A model of patent ductus arteriosus in premature lambs was created to examine the lamb's ability to handle the volume load imposed by a patent ductus arteriosus and to determine the lamb's ability to handle any additional volume load. Fifteen preterm lambs [133 +/- 2 (+/- SD) days gestation, term 145 days], whose duct...

journal_title：Pediatric research

authors： Clyman RI,Roman C,Heymann MA,Mauray F

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Irisin is a myokine secreted by skeletal muscle during physical activity. Irisin treatment increased cortical bone mineral density (BMD) in young healthy mice and restored bone and muscle mass loss in a mouse model of disuse-induced osteoporosis and muscular atrophy. In humans, Irisin was positively correlat...

journal_title：Pediatric research

authors： Colaianni G,Faienza MF,Sanesi L,Brunetti G,Pignataro P,Lippo L,Bortolotti S,Storlino G,Piacente L,D'Amato G,Colucci S,Grano M

更新日期：2019-03-01 00:00:00

abstract：:Recombinant human erythropoietin (rEpo) is neuroprotective in neonatal models of hypoxic-ischemic brain injury. However, the optimal rEpo dose, dosing interval, and number of doses for reducing brain injury are still undetermined. We compared the neuroprotective efficacy of several subcutaneous rEpo treatment regimens...

journal_title：Pediatric research

authors： Kellert BA,McPherson RJ,Juul SE

更新日期：2007-04-01 00:00:00

abstract：:Genetic variants of surfactant protein B (SP-B) have been associated with respiratory distress syndrome (RDS) in the prematurely born infant. We wished to determine linkage between RDS and SP-B single nucleotide polymorphisms (SNPs) [-18 (A/C), 1013 (A/C), 1580 (C/T), and 9306 (A/G)] or SP-B-linked microsatellite [(D2...

journal_title：Pediatric research

authors： Floros J,Thomas NJ,Liu W,Papagaroufalis C,Xanthou M,Pereira S,Fan R,Guo X,Diangelo S,Pavlovic J

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:A growing body of evidence defines inflammation as a hallmark feature of disease pathogenesis of Duchenne muscular dystrophy. To tailor potential immune modulatory interventions, a better understanding of immune dysregulation in Duchenne muscular dystrophy is needed. We now asked whether dystrophin deficienc...

journal_title：Pediatric research

authors： Kranig SA,Tschada R,Braun M,Patry C,Pöschl J,Frommhold D,Hudalla H

更新日期：2019-08-01 00:00:00

abstract：:We determined the concentrations of copper, the activities of ceruloplasmin and peptidylglycine alpha-amidating monooxygenase (PAM), and the stimulation index of PAM by the in vitro addition of copper in plasma samples obtained from three male patients with occipital horns and a milder Menkes disease phenotype, having...

journal_title：Pediatric research

authors： Prohaska JR,Tamura T,Percy AK,Turnlund JR

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:To systematically evaluate short-term efficacy of UCM versus other interventions in preterm infants. METHODS:Six engines were searched until February 2020 for randomized controlled trials (RCTs) assessing UCM versus immediate cord clamping (ICC), delayed cord clamping (DCC), or no intervention. Primary outc...

journal_title：Pediatric research

authors： Barboza JJ,Albitres-Flores L,Rivera-Meza M,Rodriguez-Huapaya J,Caballero-Alvarado J,Pasupuleti V,Hernandez AV

更新日期：2020-04-21 00:00:00

abstract：:Response characteristics of a transcutaneous PO2 electrode to step changes in PaO2 were determined. In vitro lag time and 95% response time of a transcutaneous PO2 monitor were compared to in vivo response. Release of arterial occlusion was used to produce rapid local PaO2 changes in human infants and adults. In vitro...

journal_title：Pediatric research

authors： Abu-Osba YK,Thach BT,Brouillette RT

更新日期：1981-02-01 00:00:00

abstract：:The head sizes of 38 patients, growth hormone (GH) deficient following craniospinal (n = 26) or cranial irradiation (n = 12), have been assessed before (n = 38) and on completion of GH therapy (n = 15) or at the end of a similar period of observation without GH (n = 7). These results were compared to the change in hea...

journal_title：Pediatric research

authors： Clayton PE,Shalet SM,Price DA,Surtees RA,Pearson D

更新日期：1987-10-01 00:00:00