Suppression of sigma spindle electroencephalographic activity as a measure of transient arousal after spontaneous and occlusion-evoked sighs and startles.

abstract：:Carbonic anhydrase II (CA II) is the only soluble isozyme of CA which is known to be expressed in kidney. We recently identified a deficiency of this enzyme as the basis for the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification. In order to explore the physiological i...

journal_title：Pediatric research

authors： Sly WS,Whyte MP,Krupin T,Sundaram V

更新日期：1985-10-01 00:00:00

abstract：:The factors that mediate the postnatal fall in pulmonary vascular resistance, which is crucial for normal gas exchange, are not fully understood. The endothelium has been implicated in this phenomenon, through the release of vasorelaxant factors such as nitric oxide (NO). Human pulmonary expression of endothelial NO s...

journal_title：Pediatric research

authors： Lévy M,Maurey C,Dinh-Xuan AT,Vouhé P,Israël-Biet D

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The aim of this study is to compare new pediatric nomograms for clinical parameters from 2D echocardiography. METHODS:2D pediatric echocardiographic parameters from four recent nomograms were used for statistical analysis. To assess the accuracy of the predictive models from each study, namely multivariate,...

journal_title：Pediatric research

authors： Cantinotti M,Scalese M,Giordano R,Assanta N,Marchese P,Franchi E,Viacava C,Koestenberger M,Jani V,Kutty S

更新日期：2020-04-24 00:00:00

abstract：UNLABELLED:The hGH response to an ornithin or an insulin test was measured in 105 children from 11-18 yr old with delay of growth more than 2 SD. Besides 74 subjects with normal values and 7 with complete lack of response, 24 subjects exhibited a partial rise of GH. Most of the latter had decreasing growth rate and no ...

journal_title：Pediatric research

authors： Gourmelen M,Pham-Huu-Trung MT,Girard F

更新日期：1979-04-01 00:00:00

abstract：:Immunosuppressive effects of carrageenan, a high-molecular-weight polysaccharide, on antibody and T cell responses have been previously demonstrated. However, its effect on anaphylaxis is unknown. Our objectives were to test carrageenan-mediated oral tolerance induction in young mice subsequently sensitized to a commo...

journal_title：Pediatric research

authors： Frossard CP,Hauser C,Eigenmann PA

更新日期：2001-03-01 00:00:00

abstract：:Cell-mediated immunity is not well characterized in very low birth weight infants, and abnormalities may represent a significant vulnerability to infection. This report describes 165 serial studies in 58 infants between 700 and 1300 g birth weight during the first 8 wk of life. Two ml of blood were drawn at 2-wk inter...

journal_title：Pediatric research

authors： Bussel JB,Cunningham-Rundles S,LaGamma EF,Shellabarger M

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Bradycardia and oxygen desaturation episodes are common among preterm very low birth weight (VLBW) infants in the Neonatal Intensive Care Unit (NICU), and their association with adverse outcomes such as bronchopulmonary dysplasia (BPD) is unclear. METHODS:For 502 VLBW infants we quantified bradycardias (HR ...

journal_title：Pediatric research

authors： Fairchild KD,Nagraj VP,Sullivan BA,Moorman JR,Lake DE

更新日期：2019-06-01 00:00:00

abstract：:Children with inflammatory bowel disease are known to be at risk of osteopenia. The cause of this osteopenia is likely to be multifactorial, but the inflammatory process with its characteristic overproduction of cytokines has been implicated. To investigate this possible contribution of the disease activity to the dev...

journal_title：Pediatric research

authors： Harbour ME,Gregory JW,Jenkins HR,Evans BA

更新日期：2000-08-01 00:00:00

abstract：:Quantitative determinations of cryoglobulins (IgG, IgA, IgM, and C3) were performed by a laser nephelometry microtechnique on 250 serum samples from a group of pediatric patients suspected of having immune complex-mediated disorders. Approximately 50% of these samples were cryoglobulin positive. Patients with cryoglob...

journal_title：Pediatric research

authors： Yang LC,Norman ME,Doughty RA

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND:Cardiovascular instability immediately after birth is associated with intraventricular hemorrhage (IVH) in very-low-birth-weight (VLBW) infants. For circulatory management, evaluation of organ blood flow is important. In this study, the relationship between peripheral perfusion within 48 h after birth and IV...

journal_title：Pediatric research

authors： Ishiguro A,Suzuki K,Sekine T,Sudo Y,Kawasaki H,Itoh K,Kanai M,Kato I,Sobajima H,Tamura M

更新日期：2014-02-01 00:00:00

abstract：INTRODUCTION:Cerebral white-matter (WM) abnormalities on magnetic resonance imaging (MRI) correlate with neurodevelopmental disability in infants born prematurely. RESULTS:Quantitative histological measures of WM and ventricular volumes correlated with qualitative MRI scores of WM volume loss and ventriculomegaly. Dif...

journal_title：Pediatric research

authors： Griffith JL,Shimony JS,Cousins SA,Rees SE,McCurnin DC,Inder TE,Neil JJ

更新日期：2012-02-01 00:00:00

abstract：:Neuroblastoma, a neural crest-derived childhood tumor of the sympathetic nervous system, may in some cases differentiate to a benign ganglioneuroma or regress due to apoptosis. However, the majority of neuroblastomas are diagnosed as metastatic tumors with a poor prognosis despite intensive multimodal therapy. The neu...

journal_title：Pediatric research

authors： Borgström P,Hassan M,Wassberg E,Refai E,Jonsson C,Larsson SA,Jacobsson H,Kogner P

更新日期：1999-09-01 00:00:00

abstract：:BackroundMicrocephaly can either be isolated or it may coexist with other neurological entities and/or multiple congenital anomalies, known as syndromic microcephaly. Although many syndromic cases can be classified based on the characteristic phenotype, some others remain uncertain and require further investigation. T...

journal_title：Pediatric research

authors： Tsoutsou E,Tzetis M,Giannikou K,Braoudaki M,Mitrakos A,Amenta S,Selenti N,Kanavakis E,Zafeiriou D,Kitsiou-Tzeli S,Fryssira H

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Type 1 diabetes (T1D) is a serious diagnosis with the prospect of grave short- and long-term complications and even death if poorly managed. An attempt has been made to describe how clinical and immunological deviations might influence each other close to the diagnosis of T1D. METHODS:Sixty-nine newly diagn...

journal_title：Pediatric research

authors： Rydén A,Ludvigsson J,Fredrikson M,Faresjö M

更新日期：2014-01-01 00:00:00

abstract：:The mononuclear cells of newborn infants compared to those of normal adults contain diminished activity of pyruvate kinase (PK) (14.9 +/- 1.2 vs. 22.3 +/- 1.3 mumol/10(10) cells/min) and phosphoglycerate kinase (PGK) (195 +/- 10 vs. 415 +/- 19). These deficiencies are accentuated in the cells of premature infants (4.9...

journal_title：Pediatric research

authors： Das M,Klein W,Feig SA

更新日期：1977-10-01 00:00:00

abstract：:Altered pulmonary vascular resistance might be a factor for delayed closure of the ductus arteriosus (DA) in preterm infants. Angiotensin II plays a central role in the elevation of pulmonary vascular resistance. Angiotensin II exerts its vasoconstrictor effect on the angiotensin II type 1 receptor (AT1R). Homozygous ...

journal_title：Pediatric research

authors： Treszl A,Szabo M,Dunai G,Nobilis A,Kocsis I,Machay T,Tulassay T,Vasarhelyi B

更新日期：2003-11-01 00:00:00

abstract：:It has been shown that glucocorticoids accelerate lung development by limiting alveolar formation resulting from a premature maturation of the alveolar septa. Based on these data, the aim of the present work was to analyze the influence of dexamethasone on cell cycle control mechanisms during postnatal lung developmen...

journal_title：Pediatric research

authors： Corroyer S,Schittny JC,Djonov V,Burri PH,Clement A

更新日期：2002-02-01 00:00:00

abstract：:Hyperprostaglandin E syndrome (HPS), the prenatal variant of Bartter's syndrome, is characterized by a marked and selective stimulation of prostaglandin E (PGE2) synthesis. In the study group HPS patients showed increased urinary levels of PGE2, an index of renal, and of 11 alpha-hydroxy-9,15-dioxo-2,3,4,5,20-pentanor...

journal_title：Pediatric research

authors： Nüsing RM,Schaub TP,Klein T,Schweer H,Seyberth HW

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Risk factors for diastolic dysfunction in hypertrophic cardiomyopathy (HCM) are poorly understood. We investigated the association of variants in hypoxia-response genes with phenotype severity in pediatric HCM. METHODS:A total of 80 unrelated patients <21 y and 14 related members from eight families with HC...

journal_title：Pediatric research

authors： Alkon J,Friedberg MK,Manlhiot C,Manickaraj AK,Kinnear C,McCrindle BW,Benson LN,Addonizio LJ,Colan SD,Mital S

更新日期：2012-12-01 00:00:00

abstract：:We studied the mechanisms by which C16:0 lysophosphatidylcholine (LPC) and albumin inhibit the surface activity of calf lung surfactant extract (CLSE) by using a pulsating bubble apparatus with a specialized hypophase exchange system, plus adsorption and Wilhelmy balance measurements. In the absence of inhibitors, CLS...

journal_title：Pediatric research

authors： Holm BA,Wang Z,Notter RH

更新日期：1999-07-01 00:00:00

abstract：:Hypoxic-ischemic injuries can evolve over several days, and recent studies suggest that further neuronal death may occur 6 to 72 h later. Because cerebral temperature is an important determinant of outcome during the primary injury, we investigated the effect of temperature, on outcome, during the later phases of inju...

journal_title：Pediatric research

authors： Sirimanne ES,Blumberg RM,Bossano D,Gunning M,Edwards AD,Gluckman PD,Williams CE

更新日期：1996-04-01 00:00:00

abstract：:Energy and nitrogen balances were measured in growing low birthweight infants fed either mother's expressed breast milk or a 20 kcal per ounce formula to determine whether or not there were differences between the two dietary groups in (1) the partition of energy among excretion, expenditure, and storage and (2) the r...

journal_title：Pediatric research

authors： Whyte RK,Haslam R,Vlainic C,Shannon S,Samulski K,Campbell D,Bayley HS,Sinclair JC

更新日期：1983-11-01 00:00:00

abstract：:Plasma amino acid levels in newborn babies are often measured as part of a screening for inherited metabolic disease, or less commonly as part of a nutritional assessment. We have examined certain factors which affect the levels as measured in low birth weight babies during the first 3 wk of life. As in other studies,...

journal_title：Pediatric research

authors： Scott PH,Berger HM,Wharton BA

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Abnormal PCO2 is common in infants with hypoxic ischemic encephalopathy (HIE). The objective was to determine whether hypocapnia was independently associated with unfavorable outcome (death or severe neurodevelopmental disability at 18 mo) in infants with moderate-to-severe HIE. METHODS:This was a post hoc ...

journal_title：Pediatric research

authors： Lingappan K,Kaiser JR,Srinivasan C,Gunn AJ

更新日期：2016-08-01 00:00:00

abstract：:Compliant immature airways sustain significant deformation following positive pressure ventilation. To evaluate the structural changes induced by in vivo positive pressure ventilation, tracheae of preterm lambs (107-116 d gestational age) were studied histologically. Nonventilated (group I: n = 7) and ventilated (grou...

journal_title：Pediatric research

authors： Deoras KS,Wolfson MR,Bhutani VK,Shaffer TH

更新日期：1989-11-01 00:00:00

abstract：:Biochemical analysis and morphologic observation of the iliac crest cartilage from 8-year-old girl with I-cell disease were performed. Instead of hypertrophic change of chondrocytes in the zone of cartilage-bone junction, there were small atrophic cells having many inclusion bodies accumulated with lamellar materials....

journal_title：Pediatric research

authors： Nogami H,Oohira A,Suzuki F,Tsuda K

更新日期：1981-04-01 00:00:00

abstract：:Hypercholesterolemia is common in preterm infants administered 10% Intralipid perhaps because of excess phospholipid in plasma causing efflux of cholesterol from tissues. The purpose of this study was to determine if cholesterol synthesis (as measured by plasma lathosterol) is increased in preterm infants (23-32 wk ge...

journal_title：Pediatric research

authors： Hamilton JJ,Phang M,Innis SM

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Following our clinical observation of tonic responses in response to the knee jerk in infants at very high risk for cerebral palsy (VHR infants), we systematically studied tonic responses, clonus, and reflex irradiation. We questioned (i) whether these responses occurred more often in VHR infants than in typ...

journal_title：Pediatric research

authors： Hamer EG,Dijkstra LJ,Hooijsma SJ,Zijdewind I,Hadders-Algra M

更新日期：2016-09-01 00:00:00

abstract：:In persistent hyperinsulinemic hypoglycemia of infancy, ketone body concentrations are abnormally low at times of hypoglycemia, depriving the brain of its most important alternative fuel. The neuroprotective effect of endogenous ketone bodies is evidenced by animal and human studies, but knowledge about exogenous supp...

journal_title：Pediatric research

authors： Plecko B,Stoeckler-Ipsiroglu S,Schober E,Harrer G,Mlynarik V,Gruber S,Moser E,Moeslinger D,Silgoner H,Ipsiroglu O

更新日期：2002-08-01 00:00:00

abstract：:The ciliated, mucus-secreting urn cell complex (UCC) is found swimming in the coelomic cavity of the marine invertebrate Sipunculus nudus. This cell complex, which can be maintained in suspension cultures, responds to various stimuli by hypersecreting mucus in the form of a cohesive mucus "tail." This tail can be meas...

journal_title：Pediatric research

authors： Kurlandsky LE,Berninger RW,Talamo RC

更新日期：1980-11-01 00:00:00