Abstract：
:Energy and nitrogen balances were measured in growing low birthweight infants fed either mother's expressed breast milk or a 20 kcal per ounce formula to determine whether or not there were differences between the two dietary groups in (1) the partition of energy among excretion, expenditure, and storage and (2) the relation of energy storage and nitrogen retention to weight gain. There were no significant differences between the human milk fed infants and formula fed infants in gross energy intake, metabolizable energy intake, nitrogen intake, or nitrogen retention. Energy expenditure was significantly lower in the human milk fed infants than in formula fed infants (221 kJ/(kg. day) and 244 kJ/(kg. day), respectively). There was no difference in mean energy storage between the two groups. Although weight gains were similar in both dietary groups, the ratio of energy storage to weight gain was significantly greater in infants fed with human milk (15.3 kJ/g, S.D. 2.0) than in infants fed formula (13.2 kJ/g S.D. 1.8). There was no significant difference between the two groups in the ratio of nitrogen stored to weight gain.
journal_name
Pediatr Resjournal_title
Pediatric researchauthors
Whyte RK,Haslam R,Vlainic C,Shannon S,Samulski K,Campbell D,Bayley HS,Sinclair JCdoi
10.1203/00006450-198311000-00011subject
Has Abstractpub_date
1983-11-01 00:00:00pages
891-8issue
11eissn
0031-3998issn
1530-0447journal_volume
17pub_type
杂志文章abstract：:Despite the availability of successful prevention strategies to prevent excessive hyperbilirubinemia, the neurological sequelae of bilirubin neurotoxicity (BNTx) still occur throughout the world. Kernicterus, encephalopathy due to BNTx, is now understood to be a spectrum of severity and phenotypes known as kernicterus...
journal_title：Pediatric research
pub_type： 杂志文章,评审
doi：10.1038/s41390-019-0608-0
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Later life metabolic dysfunction is a well-recognized consequence of being born small for gestational age (SGA). This study has applied metabolomics to identify whether there are changes in these pathways in prepubertal short SGA children and aimed to compare the intracellular and extracellular metabolome in...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1038/pr.2016.72
更新日期：2016-08-01 00:00:00
abstract：:Immune and lectin histochemical and microchemical methods were employed to study growth cartilage from seven cases of achondrogenesis type II (Langer-Saldino). The normal architecture of the epiphyseal and growth plate cartilage was replaced by a morphologically heterogeneous tissue. Some areas were comprised of vascu...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-198709000-00017
更新日期：1987-09-01 00:00:00
abstract：:Bone disease is an important complication among very low birth weight (VLBW, <1500 g) infants. In adults, osteoporosis is associated with polymorphisms of vitamin D receptor (VDR), estrogen receptor (ER), and collagen Ialpha1 (COLIA1) genes. However, limited information is available regarding the role of these polymor...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/01.pdr.0000242340.45676.5d
更新日期：2006-11-01 00:00:00
abstract：:In the fetal rat, nitrofen induces congenital diaphragmatic hernia (CDH) and pulmonary vascular remodeling similar to what is observed in the human condition. Airway hyperactivity is common in infants with CDH and attributed to the ventilator-induced airway damage. The purpose of this study was to test the hypothesis ...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/01.PDR.0000057986.74037.7B
更新日期：2003-05-01 00:00:00
abstract：:Serum insulin, growth hormone (GH), insulin-like growth factors (IGFs) I and II, cortisol, and albumin concentrations were measured in 15 children with kwashiorkor, 15 with marasmic-kwashiorkor, and 21 with marasmus, before and in the survivors, after nutritional rehabilitation, as well as in 10 underweight and eight ...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-198611000-00012
更新日期：1986-11-01 00:00:00
abstract：:The effect of hypertension in pregnant women on fetal maturation is an issue of considerable importance. Because of a possible role of prolactin in fetal adrenal steroidogenesis and in fetal lung maturation, we have investigated the relationship between hypertension in pregnant women and levels of prolactin and dehydr...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-198609000-00014
更新日期：1986-09-01 00:00:00
abstract：:11-Beta hydroxysteroid dehydrogenase type 2 (HSD2) oxidizes the biologically active glucocorticoid (GC), cortisol, to inactive cortisone. We characterized HSD2 gene expression and activity in human adult and fetal lung tissues and in cultured fetal lung explants, and examined the potential regulation of HSD2 in the fe...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/PDR.0b013e3180676cf3
更新日期：2007-07-01 00:00:00
abstract：:The fetal and maternal concentration of various plasma proteins alters during pregnancy. Cells in the livers of fetal hamsters accumulate serum amyloid A (SAA) and C-reactive protein (CRP) mRNA, major acute phase reactants, when lipopolysaccharide is administered to the fetal circulation. No fetal SAA or CRP mRNA resp...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-199111000-00010
更新日期：1991-11-01 00:00:00
abstract：:Neonatal susceptibility to overwhelming bacterial infection is commonly attributed to a relative deficiency in serum opsonic activity. However, few studies have compared the functional capacity of the classical complement pathway with that of the alternative complement pathway in the neonate. The opsonic activity of n...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-197912000-00008
更新日期：1979-12-01 00:00:00
abstract：:Soft bedding has been shown in epidemiologic studies to increase the risk for sudden, unexpected death in prone-sleeping infants. We compared the physical properties of conventional bedding to bedding from two sources: 1) bedding that covered the airways of victims of sudden infant death syndrome (SIDS) lying prone an...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-199407001-00002
更新日期：1994-07-01 00:00:00
abstract：:Essential fatty acid deficiency (EFAD) occurs in infants fed fat-free mixtures of glucose and amino acids. Although infusion of lipid emulsion rapidly reverses clinical symptoms, little is known about effects on tissue fatty acids. To study this question, five groups (n = 4/group) of neonatal pigs were studied. Three ...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-198412000-00027
更新日期：1984-12-01 00:00:00
abstract：:To assess the National Institutes of Health extramural activity in the area of pediatric nephrology research, the rate of submission of grant applications to the National Institutes of Health and available indicators of the quality of these applications were analyzed. This was accomplished by utilizing the grant appli...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-198511000-00001
更新日期：1985-11-01 00:00:00
abstract：BACKGROUND:Risk factors for diastolic dysfunction in hypertrophic cardiomyopathy (HCM) are poorly understood. We investigated the association of variants in hypoxia-response genes with phenotype severity in pediatric HCM. METHODS:A total of 80 unrelated patients <21 y and 14 related members from eight families with HC...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1038/pr.2012.126
更新日期：2012-12-01 00:00:00
abstract：:To clarify the prevalence of Japanese children thought to be at a risk for infection with GB virus-C (GBV-C)/hepatitis G virus (HGV), we investigated the detection rates of serum GBV-C/ HGV ribonucleic acid (RNA) by reverse transcription-seminested PCR and serum anti-HGV-E2 antibody by ELISA in 162 children with histo...
journal_title：Pediatric research
pub_type： 临床试验,杂志文章
doi：10.1203/00006450-199901000-00021
更新日期：1999-01-01 00:00:00
abstract：:Platelet-activating factor (PAF) has been implicated in the pathogenesis of gastrointestinal diseases such as necrotizing enterocolitis, Crohn's disease, and ulcerative colitis. However, neither the physiologic role of PAF in the intestine, nor the mechanisms by which PAF participates in the pathogenesis of disease ar...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-200208000-00005
更新日期：2002-08-01 00:00:00
abstract：:Our aim was to obtain a better understanding of the differences between breast-feeding and bottle-feeding, particularly with regard to how sucking performance changes from nonnutritive sucking (NNS) to nutritive sucking (NS). Twenty-two normal term infants were studied while breast-feeding at 4 and 5 d postpartum. Fiv...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/01.pdr.0000214993.82214.1c
更新日期：2006-05-01 00:00:00
abstract：:Long-term EEG monitoring (LTM) with several electrodes could be a useful tool for surveillance of the brain during the first critical days of life. This study aimed to assess the feasibility of multichannel LTM for automated analysis of EEG activity from d 1 to 3 using eight electrodes. Premature infants (GA <31 wk; n...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/PDR.0b013e31821267d2
更新日期：2011-05-01 00:00:00
abstract：:Cerebral magnetic resonance imaging (MRI) has revealed white matter changes in patients with phenylketonuria (PKU), an inborn error of metabolism with increased plasma phenylalanine level. Because the significance of these lesions is unknown, this study was undertaken to determine whether glucose metabolism was depres...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-199607000-00004
更新日期：1996-07-01 00:00:00
abstract：:New information is emerging concerning the influence of environmental factors (e.g., viruses, pollutants, nutrients) on fetal lung development and the prenatal modulation of cellular and molecular effectors essential to the control of airway function, which may shed new light into the pathogenesis of chronic obstructi...
journal_title：Pediatric research
pub_type： 杂志文章,评审
doi：10.1038/s41390-019-0657-4
更新日期：2020-01-01 00:00:00
abstract：:After an initial postnatal diuresis, neonates are in positive sodium balance. Because atrial natriuretic peptide (ANP) contributes to sodium homeostasis, this study was designed to evaluate the maturational effects of increased dietary sodium intake on cardiac ANP production. Preweaned Sprague-Dawley rat pups were art...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-199503000-00010
更新日期：1995-03-01 00:00:00
abstract：:Breast-fed infants have higher bilirubin levels than formula-fed infants, possibly because of variations in the composition of the breast milk. The aim of this study was to investigate whether there is a relationship between cytokine levels in the colostrum of nursing mothers and neonatal jaundice (NJ). Breast milk sa...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/PDR.0b013e31809871c9
更新日期：2007-08-01 00:00:00
abstract：:In a patient with extrapyramidal movement disorder and extremely low creatinine concentrations in serum and urine, in vivo proton magnetic resonance spectroscopy disclosed a generalized depletion of creatinine in the brain. Oral substitution of arginine, a substrate for creatine synthesis, resulted in an increase of b...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-199409000-00023
更新日期：1994-09-01 00:00:00
abstract：INTRODUCTION:Current advances in neonatology have improved survival among preterm and low-birth-weight infants. However, the risk of neonatal death in preterm infants is much greater than in full-term neonates and is frequently associated with infections. METHODS:Little is known about the immune status of preterm neon...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1038/pr.2012.6
更新日期：2012-05-01 00:00:00
abstract：:Prematurity is associated with delayed postnatal activation of mitochondrial oxidative phosphorylation and impaired switch from glycolytic to oxidative metabolism. Fatty acids (FA), which represent a major energy substrate in mature muscle cells, are engaged in the postnatal activation of genes of energy metabolism an...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/01.PDR.0000054687.07095.0B
更新日期：2003-04-01 00:00:00
abstract：:In view of the suggested relationship between substrate availability, fetal growth and circulating fetal IGF-I concentrations, we investigated the effect of maternal starvation on plasma IGF-I levels in the late gestation ovine fetus. Ten fetuses aged 125-130 d gestation were sampled daily from indwelling arterial cat...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-199004000-00015
更新日期：1990-04-01 00:00:00
abstract：:Local delivery of Escherichia coli beta-galactosidase gene (beta-gal) to surfactant protein-A (SP-A)-producing cells by a replication-defective recombinant adenovirus (AdCMV.beta-gal) was tested in human 8-12-wk-old fetal lung explants cultured in Waymouth's medium. In contrast to uninfected explants, direct addition ...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-199607000-00024
更新日期：1996-07-01 00:00:00
abstract：:Hemophagocytic lymphohistiocytosis (HLH) and Langerhans cell histiocytosis (LCH) are members of a group of rare heterogenous disorders, the histiocytoses, characterized by uncontrolled accumulation of pleomorphic infiltrates of leukocytes. The etiology of these diseases is mainly unknown. CD45 is a hemopoietic cell sp...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/01.PDR.0000106803.15344.72
更新日期：2004-03-01 00:00:00
abstract：:We have investigated the impaired secretion response of neonatal platelets. We compared the response of washed neonatal and adult platelets to thrombin and collagen, and to specific activators of calcium flux (inositol trisphosphate) and protein kinase C activation (oleoyl-acetyl glycerol). Neonatal platelets show no ...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-199004000-00004
更新日期：1990-04-01 00:00:00
abstract：:Alpha-mannosidosis is a lysosomal storage disorder resulting from deficient activity of lysosomal alpha-mannosidase. It has been described previously in humans, cattle, and cats, and is characterized in all of these species principally by neuronal storage leading to progressive mental deterioration. Two guinea pigs wi...
journal_title：Pediatric research
pub_type： 杂志文章
doi：10.1203/00006450-199911000-00003
更新日期：1999-11-01 00:00:00
