Cartilage of I-cell disease.

abstract：:Genetic factors are implicated in pathogenesis of neonatal hyperbilirubinemia. In this nested case-control study, we determined 1) frequency of thymine-adenine (TA)n promoter polymorphism and Gly71Arg mutation in uridine diphosphoglucuronate-glucuronosyltransferase 1A1 (UGT1A1) gene in neonates > or =35-wk gestation p...

journal_title：Pediatric research

authors： Agrawal SK,Kumar P,Rathi R,Sharma N,DAS R,Prasad R,Narang A

更新日期：2009-06-01 00:00:00

abstract：:Spleens from 1-20-wk-old guinea pigs infected in utero with Treponema pallidum and age-matched controls, born to normal and heat-killed (56 degrees C, 2 h.) T. pallidum-injected mothers, were examined for their in vitro lymphoproliferative response to phytohemagglutinin, concanavalin A, and lipopolysaccharide. Additio...

journal_title：Pediatric research

authors： Wicher V,Zhao J,Dilwith R,Burger R,Wicher K

更新日期：1997-12-01 00:00:00

abstract：:Kawasaki disease, which is characterized by systemic vasculitis causing coronary arterial involvement in childhood, shows a variety of immunoregulatory abnormalities. Especially the direct or indirect deleterious effects on endothelial cells of cytokines and anti-endothelial cell antibodies (AECA) are considered to be...

journal_title：Pediatric research

authors： Sakata K,Kita M,Imanishi J,Onouchi Z,Liu Y,Mitsui Y

更新日期：1995-10-01 00:00:00

abstract：:We used an in vitro assay to study and compare the growth-promotional activity of protein and nonprotein components in human milk (HM) and cow milk (CM) samples for infant strains of Bifidobacterium species. HM samples varied considerably in growth-promotion activity for Bifidobacterium bifidum var pennsylvanicus, Bif...

journal_title：Pediatric research

authors： Petschow BW,Talbott RD

更新日期：1991-02-01 00:00:00

abstract：:To study the course of regional metabolite concentrations during early brain development, we measured in vivo metabolites [N-acetyl-aspartate (NAA), choline-containing compounds, and myoinositol (M-Ino)] in the precentral area of the cerebrum by short echo-time single volume proton magnetic resonance spectroscopy and ...

journal_title：Pediatric research

authors： Hüppi PS,Fusch C,Boesch C,Burri R,Bossi E,Amato M,Herschkowitz N

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Kawasaki disease was well known for coronary artery abnormalities with few reports of incidence of acute kidney injury (AKI). Our aim was to identify the rate of AKI in patients with Kawasaki disease and its associated factors. METHODS:All patients with Kawasaki disease admitted to a medical center from Feb...

journal_title：Pediatric research

authors： Chuang GT,Tsai IJ,Lin MT,Chang LY

更新日期：2016-08-01 00:00:00

abstract：:Premature infants are at risk for bilirubin-associated brain damage. In cell cultures bilirubin causes neuronal apoptosis and necrosis. Ibuprofen is used to close the ductus arteriosus, and is often given when hyperbilirubinemia is at its maximum. Ibuprofen is known to interfere with bilirubin-albumin binding. We hypo...

journal_title：Pediatric research

authors： Berns M,Toennessen M,Koehne P,Altmann R,Obladen M

更新日期：2009-04-01 00:00:00

abstract：:In dissociated whole brain cell cultures from newborn mice, we have previously shown that during glucose deprivation under normoxia, D-beta-hydroxybutyrate and oleic acid are increasingly used for energy production. We now asked whether this glucose dependency of the utilization of D-beta-hydroxybutyrate and oleic aci...

journal_title：Pediatric research

authors： Bossi E,Kohler E,Herschkowitz N

更新日期：1989-11-01 00:00:00

abstract：:This study determines the inotropic effects of prostaglandin D2 (PGD2) and prostaglandin E1 (PGE1) in the isolated, arterial perfused newborn (NB) and adult (A) rabbit heart. Significant positive inotropism of PGD2 was observed at all concentrations studied (1 X 10(-17) to 1 X 10(-7) M) in the two age groups; the effe...

journal_title：Pediatric research

authors： Uemura S,Nakanishi T,Matsuoka S,Friedman WF,Jarmakani JM

更新日期：1984-12-01 00:00:00

abstract：:All-trans retinoic acid (ATRA) stimulates platelet-derived growth factor (PDGF)-A expression and enhances alveolarization in rat lungs. On d 16 of gestation, pregnant Sprague-Dawley rats were randomly assigned to either a retinoic acid group (intragastric ATRA at 10 mg/kg body weight) or a vehicle group. We punctured ...

journal_title：Pediatric research

authors： Chen CM,Chou HC,Wang LF,Lang YD,Yeh CY

更新日期：2007-11-01 00:00:00

abstract：:Sudden infant death syndrome is the most common cause of postneonatal infant mortality in the developed world. It is a diagnosis of exclusion with peak age of incidence between 2 and 6 mo. Fifty to 63% of these infants have a preexisting upper respiratory tract infection before death. We hypothesized that the immature...

journal_title：Pediatric research

authors： Blood-Siegfried J,Nyska A,Lieder H,Joe M,Vega L,Patterson R,Germolec D

更新日期：2002-10-01 00:00:00

abstract：:A child presented with obstructive sleep apnea (OSA) and a near-fatal airway obstruction and respiratory arrest shortly after receiving chloral hydrate (CH). We, therefore, hypothesize that CH might selectively depress upper airway maintaining muscles such as the genioglossus and so predispose to airway obstruction. G...

journal_title：Pediatric research

authors： Hershenson M,Brouillette RT,Olsen E,Hunt CE

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:For the second aim of the Kellogg Foundation grant, this double-blind RCT investigated the impact of plasma vitamin D metabolite 25-hydroxyvitamin D (25(OH)D) on plasma immune-mediators during pregnancy. We hypothesized that higher 25(OH)D concentrations would associate with reduced pro-inflammatory and incr...

journal_title：Pediatric research

authors： Khatiwada A,Wolf BJ,Mulligan JK,Shary JR,Hewison M,Baatz JE,Newton DA,Hawrylowicz C,Hollis BW,Wagner CL

更新日期：2020-04-20 00:00:00

abstract：:Gaucher disease, the most common of the sphingolipidoses, results from the inherited deficiency of the enzyme glucocerebrosidase (EC 3.2.1.45). Although type 2 (acute neuronopathic) Gaucher disease is associated with rapidly progressive and fatal neurologic deterioration, the pathophysiologic mechanisms leading to the...

journal_title：Pediatric research

authors： Orvisky E,Sidransky E,McKinney CE,Lamarca ME,Samimi R,Krasnewich D,Martin BM,Ginns EI

更新日期：2000-08-01 00:00:00

abstract：:Genetic typing of serum transferrin was performed in a group of 88 extremely premature infants (gestation age less than 32 wk) and in a control group of 351 full-term infants, using isoelectric focusing technique on ultrathin layer of polyacrilamide gel. A major incidence of C2 type was found among the preterm infants...

journal_title：Pediatric research

authors： Auconi P,Biagini R,Colarizi P,Pascali V

更新日期：1982-12-01 00:00:00

abstract：:The absolute and the percentage plasma NEFA pattern of healthy children, Cystic Fibrosis (C.F.) patients and their parents have been determined (table I, III, V) and compared with those of age and sex matched control subjects (table II, Iv, V). There is a striking difference in the percentage plasma NEFA pattern of C....

journal_title：Pediatric research

authors： Rogiers V,Dab I,Crokaert R,Vis HL

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND:General movements (GMs) in infants occur as fidgety movements (FMs) between postterm 9 and 20 weeks. We aimed to evaluate FMs and motor repertoire in infants with cystic fibrosis (CF) and their relation with clinical findings. METHODS:Demographic and clinical characteristics were recorded. FMs and motor rep...

journal_title：Pediatric research

authors： Tekerlek H,Mutlu A,Inal-Ince D,Livanelioglu A,Kahraman A,Eryilmaz-Polat S,Karakaya J,Ozcelik U

更新日期：2020-07-27 00:00:00

abstract：:Human Bifidobacterium sp strain bifidum (B. bifidum) was administered to BALB/c lactating mice (n = 58) and their litters (n = 327 pups) to evaluate the ingested strain's adherent properties and ability to inhibit murine rotavirus (MRV) infection. ELISA and anaerobic bacteriologic techniques were used to measure MRV s...

journal_title：Pediatric research

authors： Duffy LC,Zielezny MA,Riepenhoff-Talty M,Dryja D,Sayahtaheri-Altaie S,Griffiths E,Ruffin D,Barrett H,Rossman J,Ogra PL

更新日期：1994-06-01 00:00:00

abstract：:Innate immunity and urinary tract response play a central role in the development of urinary tract infection (UTI). Heat shock protein (HSP) 72 and Toll-like receptor (TLR) 4 are among the key elements of innate defence mechanisms. This study assesses the role of HSPA1B A(1267)G and TLR4 A(896)G polymorphisms using al...

journal_title：Pediatric research

authors： Karoly E,Fekete A,Banki NF,Szebeni B,Vannay A,Szabo AJ,Tulassay T,Reusz GS

更新日期：2007-03-01 00:00:00

abstract：:Vitamin K deficiency is a relatively common condition in neonates. However, the role of vitamin K in neonatal bone metabolism remains to be determined. Osteocalcin (OC) is the most abundant noncollagenous protein in bone, and is regulated to be gamma-carboxylated by vitamin K. In this study, we measured gamma-carboxyl...

journal_title：Pediatric research

authors： Shimizu N,Shima M,Hirai H,Nakajima S,Nishimura K,Yamaoka K,Okada S

更新日期：2002-11-01 00:00:00

abstract：:Pesticides are chemicals that are designed specifically for the purpose of killing or suppressing another living organism. Human toxicity is possible with any pesticide, and a growing body of literature has investigated possible associations with neurodevelopmental disorders. Attention deficit disorder with or without...

journal_title：Pediatric research

authors： Roberts JR,Dawley EH,Reigart JR

更新日期：2019-01-01 00:00:00

abstract：:Lung infections are a common cause of morbidity and mortality in neonates. To evaluate neonatal lung defenses against pneumococci, we challenged rats with aerosols of encapsulated pneumococci in an airborne infection apparatus. Whereas adult rats cleared greater than 95% of inhaled type 1 or type 25 pneumococci within...

journal_title：Pediatric research

authors： Coonrod JD,Jarrells MC,Bridges RB

更新日期：1987-12-01 00:00:00

abstract：:This study investigated the effects of intraventricular/periventricular blood on cerebral cAMP production and cortical cerebrovascular reactivity. Under halothane and N2O anesthesia, 3 mL of either autologous blood or artificial cerebrospinal fluid (CSF) were injected into the left caudate nucleus; volume was adequate...

journal_title：Pediatric research

authors： Pourcyrous M,Parfenova H,Shibata M,Bada HS,Korones SB,Leffler CW

更新日期：1997-09-01 00:00:00

abstract：:The diagnosis of transient renal tubular acidosis was made in a 16 months old boy. Bicarbonate titration studies revealed that the acidification defect consisted of an association of proximal and distal tubular acidosis. The effect of experimentally induced potassium depletion revealed that hyperkalemia contributed to...

journal_title：Pediatric research

authors： Donckerwolcke RA,Valk C,van Wijngaarden-Penterman MJ,van Stekelenburg GJ

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:Encephalopathic neonates undergoing therapeutic hypothermia have increased risk for coagulopathy secondary to perinatal asphyxia and effects of cooling on the coagulation enzyme cascade. Thromboelastography (TEG) allows for a comprehensive assessment of coagulation that can be regulated for temperature. TEG ...

journal_title：Pediatric research

authors： Forman KR,Wong E,Gallagher M,McCarter R,Luban NL,Massaro AN

更新日期：2014-05-01 00:00:00

abstract：:Several hours after an hypoxic-ischemic injury to the developing brain, hyperemia, then seizures, edema, and infarction can develop. The roles of nitric oxide (NO) synthesis and excitotoxin accumulation during these later phases of injury are not known. The time course of extracellular levels of amino acids within the...

journal_title：Pediatric research

authors： Tan WK,Williams CE,During MJ,Mallard CE,Gunning MI,Gunn AJ,Gluckman PD

更新日期：1996-05-01 00:00:00

abstract：:The first days of postnatal life are energetically demanding as metabolic functions change dramatically to accommodate drastic environmental and physiologic transitions after birth. It is increasingly appreciated that metabolic pathways are not only crucial for nutrition but also play important roles in regulating inf...

journal_title：Pediatric research

authors： Conti MG,Angelidou A,Diray-Arce J,Smolen KK,Lasky-Su J,De Curtis M,Levy O

更新日期：2020-01-01 00:00:00

abstract：:Prolonged unconjugated hyperbilirubinemia in infants associated with breast milk feeding is a common pediatric problem known as breast milk jaundice (BMJ). A polymorphic mutation (G71R) of bilirubin UDP-glucuronosyltransferase (UGT1A1) is a known cause of BMJ on the infantile side, but the responsible components of br...

journal_title：Pediatric research

authors： Ota Y,Maruo Y,Matsui K,Mimura Y,Sato H,Takeuchi Y

更新日期：2011-11-01 00:00:00

abstract：:Oxidant stress has been implicated as playing a role in the pathogenesis of cholestatic liver injury. The objective of this study was to determine whether the xanthine oxidase/xanthine dehydrogenase enzyme system was involved in this oxidant stress. Adult Sprague-Dawley rats were treated with the xanthine oxidase inhi...

journal_title：Pediatric research

authors： Sokol RJ,Devereaux MW,Khandwala R

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Staphylococcus aureus is the leading cause of skin and soft tissue infections (SSTIs). To develop interventions to prevent recurrent infections, household attributes and individual practices influencing S. aureus colonization must be discerned. METHODS:Households of healthy children with methicillin-resista...

journal_title：Pediatric research

authors： Mork RL,Hogan PG,Muenks CE,Boyle MG,Thompson RM,Morelli JJ,Sullivan ML,Gehlert SJ,Ross DG,Yn A,Bubeck Wardenburg J,Rzhetsky A,Burnham CD,Fritz SA

更新日期：2018-11-01 00:00:00