Effect of Kawasaki disease on migration of human umbilical vein endothelial cells.

abstract：:The classical model of gene regulation by hormones involves a hormone-bound receptor interacting with a DNA response element to increase or decrease gene transcription. Steroid hormone regulation more commonly involves atypical cis-elements, co-receptors, accessory proteins, and unique modes of interaction on differen...

journal_title：Pediatric research

authors： McNab TC,Tseng YT,Stabila JP,McGonnigal BG,Padbury JF

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Although it is commonly accepted that upper airway obstruction (UAO) increases gastroesophageal reflux (GER), the link is poorly understood and insufficiently documented. In addition, while hypoxia is often encountered in infants with UAO, its consequences on GER are virtually unknown. The two aims of the pr...

journal_title：Pediatric research

authors： Michaud A,Jia WL,Djeddi D,Samson N,Nadeau C,Geha S,Praud JP

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether small-for-gestational-age (SGA) infants born very prematurely had increased respiratory morbidity in the neonatal period and at follow-up. METHODS:Data were examined from infants recruited into the United Kingdom Oscillation Study (UKOS). Of the 797 infants who...

journal_title：Pediatric research

authors： Peacock JL,Lo JW,D'Costa W,Calvert S,Marlow N,Greenough A

更新日期：2013-04-01 00:00:00

abstract：:To delineate the role of growth hormone (GH) in the development and function of the immune system, immunological parameters including quantitative immunoglobulins, T and B lymphocytes, phytohemagglutinin lymphoproliferative response and delayed hypersensitivity skin tests were studied in nine GH-deficient children pri...

journal_title：Pediatric research

authors： Abbassi V,Bellanti JA

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:The prevalence of vitamin D (vitD) deficiency presenting as rickets is increasing worldwide. Insufficient sun exposure, vitD administration, and/or calcium intake are the main causes. However, vitD system-related genes may also have a role. METHODS:Prospective study: 109 rachitic children completed a 6-mo s...

journal_title：Pediatric research

authors： El Kholy M,Elsedfy H,Fernández-Cancio M,Hamza RT,Amr NH,Ahmed AY,Toaima NN,Audí L

更新日期：2017-02-01 00:00:00

abstract：:Oxygen is critical for multicellular existence. Its reduction to water by the mitochondrial electron transport chain helps supply the metabolic demands of human life. The incompletely reduced, reactive oxygen byproducts of this reaction, however, can be quite toxic. In this review, we explore the mechanisms responsibl...

journal_title：Pediatric research

authors： Maltepe E,Saugstad OD

更新日期：2009-03-01 00:00:00

abstract：:Progress has been made in the reduction of morbidity and mortality from neonatal sepsis. However, diagnosis continues to rely primarily on conventional microbiologic techniques, which can be inaccurate. The objective of this review is to provide the clinician with an overview of the current information available on di...

journal_title：Pediatric research

authors： Iroh Tam PY,Bendel CM

更新日期：2017-10-01 00:00:00

abstract：:Although the use of antenatal glucocorticoids has resulted in decreased neonatal morbidity/mortality, recent animal studies have raised concerns regarding adverse effects of these medications on postnatal cardiovascular function. We hypothesized that antenatal betamethasone (Beta) exposure alters cerebral vascular rea...

journal_title：Pediatric research

authors： Eckman DM,Kerr BA,Fuloria M,Simandle SA,Watt SE,Rose JC,Figueroa JP

更新日期：2010-10-01 00:00:00

abstract：:We hypothesized that cardiac and respiratory modulation of postganglionic peroneal activity appeared in an age-related manner. In anesthetized, paralyzed and artificially ventilated piglets, simultaneous recordings of efferent phrenic and peroneal discharges were obtained during hyperoxia (fraction of inspired oxygen,...

journal_title：Pediatric research

authors： Sica AL,Hundley BW,Gootman PM

更新日期：1996-01-01 00:00:00

abstract：:To determine whether human milk contained soluble receptors and cytokine antagonists that might contribute to its anti-inflammatory properties, ELISA and enzyme-amplified sensitivity immunoassay methods were used to quantitate soluble intercellular and vascular cell adhesion molecules, soluble E-selectin, soluble IL-6...

journal_title：Pediatric research

authors： Buescher ES,Malinowska I

更新日期：1996-12-01 00:00:00

abstract：:The effects of early protein-deficiency on lung development were studied in the rat. Newborn male rats were nursed in groups of eight. Control dams and pups received a 15% protein diet during the whole experiment. Test mothers only received 12 and 8% proteins from the 7th and the 14th day of lactation. Test rats fed a...

journal_title：Pediatric research

authors： Kalenga M,Henquin JC

更新日期：1987-07-01 00:00:00

abstract：:Seven essentially healthy term infants who received gentamicin starting on the 1st day of life for prolonged rupture of membranes and maternal fever were compared with nine healthy term infants to determine whether this drug induces alterations in the auditory pathway. The auditory pathway was studied on the 3rd day o...

journal_title：Pediatric research

authors： Kohelet D,Usher M,Arbel E,Arlazoroff A,Goldberg M

更新日期：1990-09-01 00:00:00

abstract：:We have previously demonstrated that enterally administered heparin-binding EGF-like growth factor (HB-EGF) produced in Escherichia coli decreases the incidence and severity of intestinal injury in a neonatal rat model of necrotizing enterocolitis (NEC). In preparation for upcoming human clinical trials, large-scale p...

journal_title：Pediatric research

authors： Radulescu A,Zorko NA,Yu X,Besner GE

更新日期：2009-04-01 00:00:00

abstract：:Localized proton magnetic resonance spectra were recorded from human cerebellum in vivo with a 1.5-T magnet. The spectra from healthy adults and preterm and term babies showed resonances from N-acetylaspartate, creatine and phosphocreatine, choline-containing compounds such as phosphocholine and glycerophosphocholine,...

journal_title：Pediatric research

authors： Hüppi PS,Posse S,Lazeyras F,Burri R,Bossi E,Herschkowitz N

更新日期：1991-12-01 00:00:00

abstract：:This study was carried out to determine the influence and site of action of N omega-nitro-L-arginine methylester, an L-arginine analogue, on basal pulmonary vascular tone and hypoxic vasoconstriction in neonatal pig lungs. We studied isolated lungs from pigs, age 14.5 +/- 0.5 (SD) d and weight 3.6 +/- 0.7 kg, perfused...

journal_title：Pediatric research

authors： Nelin LD,Dawson CA

更新日期：1993-09-01 00:00:00

abstract：:In a patient with extrapyramidal movement disorder and extremely low creatinine concentrations in serum and urine, in vivo proton magnetic resonance spectroscopy disclosed a generalized depletion of creatinine in the brain. Oral substitution of arginine, a substrate for creatine synthesis, resulted in an increase of b...

journal_title：Pediatric research

authors： Stöckler S,Holzbach U,Hanefeld F,Marquardt I,Helms G,Requart M,Hänicke W,Frahm J

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:After birth, breastfeeding is the exclusive source of hormonal signaling between mother and infant. Hospitalized infants often receive donor milk when their own mother's milk is unavailable. METHODS:The presence of insulin, leptin, cortisol, progesterone, and testosterone was examined in samples from milk b...

journal_title：Pediatric research

authors： Vass RA,Bell EF,Colaizy TT,Schmelzel ML,Johnson KJ,Walker JR,Ertl T,Roghair RD

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Macrosomia and child obesity are growing health-care issues worldwide. The purpose of the study was to evaluate how extremely high or low birth weight affects metabolic markers evaluated in newborn screening. METHODS:The study was register-based and included full-term singletons born in Iceland from 2009 to...

journal_title：Pediatric research

authors： Vidarsdottir H,Thorkelsson T,Halldorsson TI,Bjarnason R,Geirsson RT,Rinaldo P,Franzson L

更新日期：2020-06-29 00:00:00

abstract：:Several studies analyzing the immune responses in patients with cow's milk allergy (CMA) have used T-cell lines or T-cell clones that require prolonged in vitro cell culturing and may result in a switched cell phenotype and function. We investigated immune responses to beta-lactoglobulin (b-LG) in peripheral blood mon...

journal_title：Pediatric research

authors： Vocca I,Canani RB,Camarca A,Ruotolo S,Nocerino R,Radano G,Del Mastro A,Troncone R,Gianfrani C

更新日期：2011-12-01 00:00:00

abstract：:Insulin administration is the primary therapy for type 1 diabetes mellitus (T1DM). Current available insulin therapies do not successfully enable children with T1DM to reach glycemic goals without side effects such as hypoglycemia and weight gain. Pramlintide is a synthetic analog of human amylin that acts in conjunct...

journal_title：Pediatric research

authors： Raman VS,Heptulla RA

更新日期：2009-04-01 00:00:00

abstract：:To determine whether epidermal growth factor (EGF) or EGF-like transforming growth factors (TGFs) are present in ovine fetal tissues, we have tested acid-ethanol extracts of ovine fetal kidney for the ability to induce anchorage-independent growth of normal rat kidney fibroblasts in soft agar and to compete with 125I-...

journal_title：Pediatric research

authors： Freemark M,Comer M

更新日期：1987-11-01 00:00:00

abstract：:Epidermal growth factor (EGF), a potent mitogen present in milk, is postulated to play an important physiologic role in the ontogeny of the intestine. An artificial rat milk, free of EGF, was developed and fed to newborn rats in an effort to evaluate the physiologic role of EGF on intestinal glucose transport. Compari...

journal_title：Pediatric research

authors： Greene HL,Moore MC,Said HM,Ghishan FK,Orth DN

更新日期：1987-04-01 00:00:00

abstract：:Nitric Oxide (NO) can be cytotoxic or cytoprotective depending on amount and location of its generation. eNOS is important in modulating blood flow and is allosterically regulated. Inducible NOS (iNOS) tends to produce large quantities of NO leading to cell injury. We studied the role and regulation of NOS in carbon t...

journal_title：Pediatric research

authors： Liu H,Subramony C,Nowicki M

更新日期：2008-06-01 00:00:00

abstract：:The effect of various lipids, proteins, and other substances on the adsorption rate of dipalmitoyl phosphatidylcholine (DPC) was investigated. Each substance was added to a sonicated suspension of DPC in saline, and the surface pressure of the adsorbed surface film was measured using a platinum plate suspended from an...

journal_title：Pediatric research

authors： Meban C

更新日期：1981-07-01 00:00:00

abstract：:Spontaneous preterm birth is a serious and common pregnancy complication associated with hormonal dysregulation, infection, inflammation, immunity, rupture of fetal membranes, stress, bleeding, and uterine distention. Heredity is 25-40% and mostly involves the maternal genome, with contribution of the fetal genome. Si...

journal_title：Pediatric research

authors： Hallman M,Haapalainen A,Huusko JM,Karjalainen MK,Zhang G,Muglia LJ,Rämet M

更新日期：2019-03-01 00:00:00

abstract：:The isobutyryl-CoA dehydrogenase (IBD) enzyme is involved in the degradation of valine. IBD deficiency was first reported in 1998 and subsequent genetic investigations identified acyl-CoA dehydrogenase (ACAD) 8, now IBD, as the gene responsible for IBD deficiency. Only three individuals homozygous or compound heterozy...

journal_title：Pediatric research

authors： Pedersen CB,Bischoff C,Christensen E,Simonsen H,Lund AM,Young SP,Koeberl DD,Millington DS,Roe CR,Roe DS,Wanders RJ,Ruiter JP,Keppen LD,Stein Q,Knudsen I,Gregersen N,Andresen BS

更新日期：2006-09-01 00:00:00

abstract：:Small for gestational age (SGA) children have a higher prevalence of cardiovascular risk factors at a young age. It is not known whether this increased risk is caused by their size at birth, a familial predisposition for cardiovascular disease or smallness at birth or a combination of these factors. The cardiovascular...

journal_title：Pediatric research

authors： De Kort SW,Van Dijk M,Willemsen RH,Ester WA,Viet L,De Rijke YB,Hokken-Koelega AC

更新日期：2008-07-01 00:00:00

abstract：:As the mechanisms controlling the amount and timing of growth saltations are not well understood, the identification of physiologic coupling in weight and length growth are important for further understanding normal growth biology. Thirty-four healthy infants (13 males, 21 females) participated in a longitudinal growt...

journal_title：Pediatric research

authors： Lampl M,Thompson AL,Frongillo EA

更新日期：2005-12-01 00:00:00

abstract：:Increased expression of CD38 on CD8(+) T cells is associated with activation of the immune system, progression of HIV disease, and death in adults. The prognostic significance of these cells in HIV-infected children, where the picture is complicated by age-related differences in CD38 expression, remains controversial....

journal_title：Pediatric research

authors： Sherman GG,Scott LE,Galpin JS,Kuhn L,Tiemessen CT,Simmank K,Meddows-Taylor S,Meyers TM

更新日期：2002-06-01 00:00:00

abstract：:The ability of intravenously administered glucose or glucose oligosaccharides to supply 12% of the energy requirement of the growing miniature pig was determined. All pigs were fed a stock diet from days 5-28 of life, and a central venous catheter was inserted at 29 days. For the next 30 days, all pigs were fed both e...

journal_title：Pediatric research

authors： Andersen DW,Filer LJ Jr,Wu-Rideout YC,White LB,Stegink LD

更新日期：1982-04-01 00:00:00