Effect of neonatal exposure to genistein on bone metabolism in mice at adulthood.

abstract：:Alveolar macrophages were isolated from three cystic fibrosis patients, and the structure and function of these cells were compared to that of normal alveolar macrophages. The cystic fibrosis (CF) and normal alveolar macrophages were able to phagocytize Pseudomonas in the presence of normal serum, but cells from both ...

journal_title：Pediatric research

authors： Thomassen MJ,Demko CA,Wood RE,Tandler B,Dearborn DG,Boxerbaum B,Kuchenbrod PJ

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:Genotyping tests were developed to attenuate the impact of viral resistance. Information about the efficacy in genotype base antiretroviral therapy in children is rare and even more in low- and middle-income countries. METHODS:Sixteen children with antiretroviral therapy (ART) failure and triple-class drug-...

journal_title：Pediatric research

authors： Huerta-García G,Vazquez-Rosales JG,Mata-Marín JA,Peregrino-Bejarano L,Flores-Ruiz E,Solórzano-Santos F

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Bronchopulmonary dysplasia (BPD) is an important cause of morbidity. The aim of this study was to evaluate the preventive effect of cytidine 5'-diphosphocholine (CDP-choline) treatment on hyperoxic lung injury in a neonatal rat model. METHODS:A total of 30 newborn pups were divided into control, hyperoxia, ...

journal_title：Pediatric research

authors： Cetinkaya M,Cansev M,Kafa IM,Tayman C,Cekmez F,Canpolat FE,Tunc T,Sarici SU

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Prematurity may influence the levels of amino acids, enzymes, and endocrine markers obtained through newborn screening. Identifying which analytes are the most affected by degree of prematurity could provide insight into how prematurity impacts metabolism. METHODS:Analytes from blood spots assayed by Newbor...

journal_title：Pediatric research

authors： Wilson K,Hawken S,Ducharme R,Potter BK,Little J,Thébaud B,Chakraborty P

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Kawasaki disease (KD) is associated with expression and methylation of Fc gamma receptor genes. We characterized immunoglobulin A (IgA), IgE, IgG, and IgM receptor expression levels in KD. METHODS:Fc receptor expression levels were characterized using GeneChip Human Transcriptome Array 2.0 (HTA 2.0) with 18...

journal_title：Pediatric research

authors： Chang LS,Ming-Huey Guo M,Lo MH,Kuo HC

更新日期：2019-12-09 00:00:00

abstract：:Oxidant stress has been implicated as playing a role in the pathogenesis of cholestatic liver injury. The objective of this study was to determine whether the xanthine oxidase/xanthine dehydrogenase enzyme system was involved in this oxidant stress. Adult Sprague-Dawley rats were treated with the xanthine oxidase inhi...

journal_title：Pediatric research

authors： Sokol RJ,Devereaux MW,Khandwala R

更新日期：1998-09-01 00:00:00

abstract：:Cerebellar injury has been increasingly recognized as a complication of preterm birth, with decreased cerebellar volumes seen on follow-up neuroimaging. A cohort of 38 preterm newborns, including 14 with two scans, was studied with MRI, including single-shot fast spin-echo diffusion tensor imaging (DTI) sequence speci...

journal_title：Pediatric research

authors： Tam EW,Ferriero DM,Xu D,Berman JI,Vigneron DB,Barkovich AJ,Miller SP

更新日期：2009-07-01 00:00:00

abstract：:Apoptosis of CD4+ and CD8+ T cells has been shown in peripheral blood mononuclear cells (PBMCs) from HIV-infected adults analyzed after overnight culture. Because cell death may be an artifact of in vitro culture, and because there is little information on apoptosis in pediatric HIV disease, we undertook a cross-secti...

journal_title：Pediatric research

authors： Cotton MF,Ikle DN,Rapaport EL,Marschner S,Tseng PO,Kurrle R,Finkel TH

更新日期：1997-11-01 00:00:00

abstract：:Blood volume (BV), red cell mass (RCM; Cr-51) and plasma volume (125I-labeled albumin) were measured in 205 piglets from 28 litters shortly after birth. Spontaneous cord rupture in healthy piglets occurred during delivery (n = 25) or within 190 sec of birth (n = 82). Spontaneous and induced delay of cord rupture resul...

journal_title：Pediatric research

authors： Linderkamp O,Betke K,Güntner M,Jap GH,Riegel KP,Walser K

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Long-term prefrontal cortex (PFC)- and hippocampus-based cognitive deficits are the sequelae of perinatal iron deficiency, despite iron supplementation starting in the newborn period. Whether high-dose iron supplementation prevents these deficits is yet to be determined. METHODS:Perinatal iron deficiency wa...

journal_title：Pediatric research

authors： Rao R,Tkac I,Unger EL,Ennis K,Hurst A,Schallert T,Connor J,Felt B,Georgieff MK

更新日期：2013-01-01 00:00:00

abstract：:We describe a method based on a Fabry-Perot interferometer at the tip of an optic fiber with a diameter of 0.25 mm for direct measurement of tracheal pressure in pediatric respiratory monitoring. The response time of the pressure transducer and its influence on the resistance of pediatric endotracheal tubes (internal ...

journal_title：Pediatric research

authors： Sondergaard S,Karason S,Hanson A,Nilsson K,Hojer S,Lundin S,Stenqvist O

更新日期：2002-03-01 00:00:00

abstract：:An imbalance in apoptosis or survival of immune cells plays an essential role in the pathophysiology of sepsis. Phagocytosis-induced cell death (PICD) is a common result of the pathogen-host cell interaction mediated by reactive oxygen species (ROS). Neonatal sepsis is frequently characterized by hyperinflammation. Co...

journal_title：Pediatric research

authors： Gille C,Leiber A,Spring B,Kempf VA,Loeffler J,Poets CF,Orlikowsky TW

更新日期：2008-01-01 00:00:00

abstract：:Genetic typing of serum transferrin was performed in a group of 88 extremely premature infants (gestation age less than 32 wk) and in a control group of 351 full-term infants, using isoelectric focusing technique on ultrathin layer of polyacrilamide gel. A major incidence of C2 type was found among the preterm infants...

journal_title：Pediatric research

authors： Auconi P,Biagini R,Colarizi P,Pascali V

更新日期：1982-12-01 00:00:00

abstract：:Many trials of mesenchymal stem cells (MSCs) have been published in the past 5-6 y. MSCs inhibit T-cell alloreactivity in vitro by soluble factors and direct cell-to-cell contact. They are safe to infuse in humans with no acute toxicity and no ectopic tissue formation. Promising results of MSC infusion for graft-vs.-h...

journal_title：Pediatric research

authors： Dalal J,Gandy K,Domen J

更新日期：2012-04-01 00:00:00

abstract：:Leukotriene B4 (LTB4) is a product of arachidonic acid metabolism and a potent chemoattractant for adult polymorphonuclear leukocytes (PMN). LTB4 may be an important inflammatory mediator in neonatal lung disorders such as bronchopulmonary dysplasia, but neonatal PMN chemotaxis to LTB4 has not been studied. We compare...

journal_title：Pediatric research

authors： Dos Santos C,Davidson D

更新日期：1993-03-01 00:00:00

abstract：:Several studies analyzing the immune responses in patients with cow's milk allergy (CMA) have used T-cell lines or T-cell clones that require prolonged in vitro cell culturing and may result in a switched cell phenotype and function. We investigated immune responses to beta-lactoglobulin (b-LG) in peripheral blood mon...

journal_title：Pediatric research

authors： Vocca I,Canani RB,Camarca A,Ruotolo S,Nocerino R,Radano G,Del Mastro A,Troncone R,Gianfrani C

更新日期：2011-12-01 00:00:00

abstract：:Thrombocytopenia in the first days of life, in association with evidence of reduced megakaryocytopoiesis and platelet production at birth, is common in sick preterm babies. Thrombopoietin (Tpo) is the major regulator of platelet production in adults. However, these babies have low Tpo levels at birth, suggesting that ...

journal_title：Pediatric research

authors： Watts TL,Murray NA,Roberts IA

更新日期：1999-07-01 00:00:00

abstract：:Blood mononuclear cells from newborns and from adults, immune or nonimmune to herpes simplex virus, were cultured with IL 2 and herpes simplex virus and the amount of gamma-interferon in the supernatant measured after 3 days. The newborn and nonimmune adult cells made equivalent trace amounts of gamma-interferon in cu...

journal_title：Pediatric research

authors： Hayward AR,Herberger M,Saunders D

更新日期：1986-05-01 00:00:00

abstract：:Twenty-two reported cases of neuroblastoma missed by the mass screening programs were reviewed (six cases in Sapporo City where a quantitative measurement for both vanillylmandelic acid (VMA) and homovanillic acid (HVA) is used and 16 cases in the districts of qualitative judgment only for VMA), and some potential fac...

journal_title：Pediatric research

authors： Nishi M,Miyake H,Takeda T,Takasugi N,Sato Y,Hanai J,Kawai T

更新日期：1989-12-01 00:00:00

abstract：:Lung infections are a common cause of morbidity and mortality in neonates. To evaluate neonatal lung defenses against pneumococci, we challenged rats with aerosols of encapsulated pneumococci in an airborne infection apparatus. Whereas adult rats cleared greater than 95% of inhaled type 1 or type 25 pneumococci within...

journal_title：Pediatric research

authors： Coonrod JD,Jarrells MC,Bridges RB

更新日期：1987-12-01 00:00:00

abstract：:Labeled choline incorporation into adult rat lung alveolar epithelial cells and adult rat lung fibroblasts in monolayer culture was determined after incubation with insulin (Ins) 10 micrograms/ml, Dexamethasone (Dex) 10(-6)M, or no drug (ND). Incubation periods were 1, 3, 4, and 5 hours. The lecithin (phosphatidyl cho...

journal_title：Pediatric research

authors： Sharp MJ,Borer RC Jr,Vadnay L,Douglas WH

更新日期：1980-07-01 00:00:00

abstract：:We investigated early postnatal changes of the mesenteric circulation and its relationship to the systemic circulation in two groups of newborn infants. Group I (n = 10) was studied before the first feeding at 1 h and preprandially at 6 and 24 h. Group II (n = 10) was studied before the first feeding at 2 h of age and...

journal_title：Pediatric research

authors： Martinussen M,Brubakk AM,Linker DT,Vik T,Yao AC

更新日期：1994-09-01 00:00:00

abstract：:Human intestinal mucosa consists of highly active epithelial cells in continual renewal and differentiation processes located at different portions of the villi. The crypt contains abundant replicating cells which, upon reaching the villus tip, acquire their fully differentiated state. Besides its well recognized role...

journal_title：Pediatric research

authors： Delvin EE,Lopez V,Levy E,Ménard D

更新日期：1996-11-01 00:00:00

abstract：:Late Onset Central Hypoventilation Syndrome associated with Hypothalamic Dysfunction (LO-CHS/HD) is a distinct entity among the clinical and genetic heterogeneous group of patients with late onset central hypoventilation. Here we report a series of 13 patients with LO-CHS/HD. Rapid onset obesity is the first symptom o...

journal_title：Pediatric research

authors： De Pontual L,Trochet D,Caillat-Zucman S,Abou Shenab OA,Bougneres P,Crow Y,Cunningham S,Esteva B,Heberle LC,Leger J,Pinto G,Polak M,Shafik MH,Straus C,Trang H,Munnich A,Lyonnet S,Desguerre I,Amiel J

更新日期：2008-12-01 00:00:00

abstract：:Neutrophils contribute to ischemic brain injury in adult animals. The role of neutrophils in perinatal hypoxic-ischemic (HI) brain injury is unknown. Allopurinol reduces neutrophil accumulation after tissue ischemia and is protective against HI brain injury. This study was designed to investigate how neutrophils contr...

journal_title：Pediatric research

authors： Hudome S,Palmer C,Roberts RL,Mauger D,Housman C,Towfighi J

更新日期：1997-05-01 00:00:00

abstract：:Beta cells are partially replaced in neonatal rodents after deletion with streptozotocin (STZ). Exposure of pregnant rats to a low protein (LP) diet impairs endocrine pancreas development in the offspring, leading to glucose intolerance in adulthood. Our objective was to determine whether protein restriction has a sim...

journal_title：Pediatric research

authors： Cox AR,Gottheil SK,Arany EJ,Hill DJ

更新日期：2010-07-01 00:00:00

abstract：:Sarcoplasmic reticulum (SR) Ca release has been shown not to be the predominant mechanism responsible for excitation-contraction (E-C) coupling in fetal myocytes. However, most of the studies have been conducted either on primary cultures or acutely isolated cells, in which an apparent reduction of ryanodine receptor ...

journal_title：Pediatric research

authors： Takizawa M,Ishiwata T,Kawamura Y,Kanai T,Kurokawa T,Nishiyama M,Ishida H,Asano Y,Nonoyama S

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:We previously demonstrated that the proliferative response to lipopolysaccharide (LPS) in cord blood mononuclear cells (CBMCs) is negatively correlated with the induced expression of interleukin (IL)-4. Our aim, therefore, was to examine whether an impaired cellular response to LPS in infancy is associated w...

journal_title：Pediatric research

authors： Goldberg MR,Elizur A,Luknar-Gabor N,Koch P,Tovbin J,Katz Y

更新日期：2013-08-01 00:00:00

abstract：:Pups delivered by rats fed during pregnancy a choline-deficient (CD) diet containing 1% N,N-dimethylaminoethanol (DME) die within 36 hr of birth. The concentrations of sphingomyelins, phosphatidyl cholines, and disaturated phosphatidyl cholines in the lungs of these pups are lower than those in the lungs of pups deliv...

journal_title：Pediatric research

authors： Katyal SL,Lombardi B

更新日期：1978-09-01 00:00:00

abstract：:To investigate the role of nutrition in the regulation of IGFs during the perinatal period, 10-d-old rats were infused intravenously with various concentrations of nutrients for 24 h. Breast-fed litter mates served as controls. The effect of caloric intake on concentrations of IGF-I and IGF-II as well as IGF-binding p...

journal_title：Pediatric research

authors： Philipps A,Drakenberg K,Persson B,Sjögren B,Eklöf AC,Hall K,Sara V

更新日期：1989-08-01 00:00:00