Noninvasive assessments of oxygen delivery from the microcirculation to skin in hypothermia-treated asphyxiated newborn infants.

abstract：:Iron is essential for fetal organ development, but the effect of isolated iron deficiency on nephrogenesis is unknown. Human premature infants are at risk for disrupted nephrogenesis because glomerular development is incomplete until 36-wk gestation. We modeled the effects of iron on postnatal glomerulogenesis in four...

journal_title：Pediatric research

authors： Drake KA,Sauerbry MJ,Blohowiak SE,Repyak KS,Kling PJ

更新日期：2009-12-01 00:00:00

abstract：:Establishment of Helicobacter pylori infection as an etiologic agent of peptic ulcer disease and other gastric pathologies marked a revolution in gastroenterology which spurred an enormous interest in gastric physiology and immunology research. The association was soon also demonstrated in children as well. Applicatio...

journal_title：Pediatric research

authors： Blanchard TG,Czinn SJ

更新日期：2017-01-01 00:00:00

abstract：:Pediatric research may be entering a period of failure to thrive. This is despite impressive scientific achievements, significant financial benefits, intriguing unanswered questions and a rewarding life for the pediatric researcher. Many of the difficulties are financial and situational, including small departments an...

journal_title：Pediatric research

authors： Stiehm ER

更新日期：1985-06-01 00:00:00

abstract：:The influence of maternal stress during pregnancy on the postpartum iron status and immune maturation of infants was investigated in a nonhuman primate model. Forty infant rhesus monkeys were generated from two types of disturbed pregnancies, early or late gestation stress, and compared with 24 undisturbed controls. P...

journal_title：Pediatric research

authors： Coe CL,Lubach GR,Shirtcliff EA

更新日期：2007-05-01 00:00:00

abstract：:In 1975-1976, an experiment was performed at three sites of an HMO to investigate the effect of a protocol on drug prescribing for otitis media. A large and unexpected difference in encounter rates for otitis media was found among the sites. In the first 6 months of 1975, the rate of children less than 15 years with a...

journal_title：Pediatric research

authors： Bush PJ,Rabin DL

更新日期：1980-10-01 00:00:00

abstract：:Pulmonary surfactant proteins SP-B and SP-C were isolated from lavage fluids of bovine lungs and recombined (lipid/proteins, 9/1, wt/wt) with dipalmitoyl phosphatidylcholine for testing in vitro and in surfactant-deficient adult rats. Using a pulsating bubble surfactometer, we found that inflation pressures of bubbles...

journal_title：Pediatric research

authors： Smith GB,Taeusch HW,Phelps DS,Keough KM

更新日期：1988-05-01 00:00:00

abstract：:In the fetal rat, nitrofen induces congenital diaphragmatic hernia (CDH) and pulmonary vascular remodeling similar to what is observed in the human condition. Airway hyperactivity is common in infants with CDH and attributed to the ventilator-induced airway damage. The purpose of this study was to test the hypothesis ...

journal_title：Pediatric research

authors： Belik J,Davidge ST,Zhang W,Pan J,Greer JJ

更新日期：2003-05-01 00:00:00

abstract：INTRODUCTION:Very early preterm infants (VPIs) are exposed to unpredictable noise in neonatal intensive care units. Their ability to perceive moderate acoustic environmental changes has not been fully investigated. RESULTS:Physiological values of the 598 isolated sound peaks (SPs) that were 5-10 and 10-15 dB slow-resp...

journal_title：Pediatric research

authors： Kuhn P,Zores C,Pebayle T,Hoeft A,Langlet C,Escande B,Astruc D,Dufour A

更新日期：2012-04-01 00:00:00

abstract：:A girl presented with an important growth retardation, hepatomegaly, fasting hypoglycemia, lactic acidosis, increased serum cholesterol, triglycerides and uric acid, and increased liver glycogen (7.5%). There was no rise in blood glucose after IV galactose or fructose, but glucagon gave a delayed response. Type Ib gly...

journal_title：Pediatric research

authors： Corbeel L,Hue L,Lederer B,De Barsy T,Van den Berghe G,Devlieger H,Jaeken J,Bracke P,Eeckels R

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:The present study examined the association between 9/11-related adolescent behavioral problems on mental health outcomes in early adulthood. METHODS:Data from enrollees of the World Trade Center Health Registry, who completed at least one adolescent (2006-2007 or 2011-2012) and adult survey (2011-2012 or 20...

journal_title：Pediatric research

authors： Gargano LM,Locke S,Li J,Farfel MR

更新日期：2018-08-01 00:00:00

abstract：:To determine the effects of age, feeding regimen, and antenatal glucocorticoids on intestinal permeability, preterm infants (n = 132) were stratified by gestational age and by diet (mothers' own milk versus preterm formula), and assigned randomly to one of four feeding regimens: early-continuous, early-bolus, standard...

journal_title：Pediatric research

authors： Shulman RJ,Schanler RJ,Lau C,Heitkemper M,Ou CN,Smith EO

更新日期：1998-10-01 00:00:00

abstract：:To evaluate the maturation of glucose homeostasis in the small for gestational age (SGA) neonate, glucose kinetics were measured with 78% enriched D-[U-13C]glucose by the prime plus constant infusion technique in nine SGA infants and compared with the rate obtained in seven term appropriate for gestational age infants...

journal_title：Pediatric research

authors： Cowett RM,Susa JB,Oh W,Schwartz R

更新日期：1984-01-01 00:00:00

abstract：:Neutrophils contribute to ischemic brain injury in adult animals. The role of neutrophils in perinatal hypoxic-ischemic (HI) brain injury is unknown. Allopurinol reduces neutrophil accumulation after tissue ischemia and is protective against HI brain injury. This study was designed to investigate how neutrophils contr...

journal_title：Pediatric research

authors： Hudome S,Palmer C,Roberts RL,Mauger D,Housman C,Towfighi J

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Neonatal encephalopathy (NE) carries high risk for neurodevelopmental impairments. Therapeutic hypothermia (TH) reduces this risk, particularly for moderate encephalopathy (ME). Nevertheless, these infants often have subtle functional deficits, including abnormal memory function. Detection of deficits at the...

journal_title：Pediatric research

authors： Pfister KM,Zhang L,Miller NC,Hultgren S,Boys CJ,Georgieff MK

更新日期：2016-12-01 00:00:00

abstract：:Children treated for acute lymphoblastic leukemia may develop reduced bone mineral density during treatment, but there is little information on the mechanisms involved. In a prospective, longitudinal study on 15 children with ALL, we undertook serial measurements of markers of bone and collagen turnover, insulin-like ...

journal_title：Pediatric research

authors： Crofton PM,Ahmed SF,Wade JC,Elmlinger MW,Ranke MB,Kelnar CJ,Wallace WH

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Gender is increasingly recognized as an important influence on brain development, disease susceptibility, and response to pharmacologic/rehabilitative treatments. In regenerative medicine, it remains entirely unknown whether there is an interaction between transplanted stem cells and host gender that might b...

journal_title：Pediatric research

authors： Ashwal S,Ghosh N,Turenius CI,Dulcich M,Denham CM,Tone B,Hartman R,Snyder EY,Obenaus A

更新日期：2014-05-01 00:00:00

abstract：:The purpose of this study was to investigate the effect of constant light in a neonatal care unit on the development of the sleep-and-wakefulness rhythm in preterm infants. Two groups of infants (57 preterm infants without other complications and 58 healthy term infants) were prospectively studied over infancy by a da...

journal_title：Pediatric research

authors： Shimada M,Segawa M,Higurashi M,Akamatsu H

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:The rate of accrual of muscle mass in neonates has not been assessed. We describe the D3-creatine (D3Cr) dilution method, a noninvasive assessment of muscle mass in neonates. METHODS:A total of 76 neonates >26-week-old corrected gestational age were enrolled and measured at 2-week intervals while admitted t...

journal_title：Pediatric research

authors： Evans WJ,Scottoline B,Imam F,Hellerstein M,Garton K,Czerwieniec G,Nyangau E,Shankaran M

更新日期：2020-09-12 00:00:00

abstract：:Heart rate variability (HRV) is reported increasingly in pediatric research, but different strategies used to identify and manage potential outlier beats impact HRV parameter values in adults and animals. Do they in pediatrics? To compare the impact of different strategies to identifying and managing outliers, we used...

journal_title：Pediatric research

authors： Kemper KJ,Hamilton C,Atkinson M

更新日期：2007-09-01 00:00:00

abstract：:This report describes a third mucopolysaccharidosis in animals: canine mucopolysaccharidosis VII. The affected dog was the offspring of a father-daughter mating. Weakness in the rear legs was evident at 8 weeks of age and became progressively worse. He had a large head, a shortened maxilla, and corneal granularities. ...

journal_title：Pediatric research

authors： Haskins ME,Desnick RJ,DiFerrante N,Jezyk PF,Patterson DF

更新日期：1984-10-01 00:00:00

abstract：:Supine sleeping, recommended to prevent sudden infant death, should be started in the delivery hospital, but meets concern that neonates may exhibit more intermittent hypoxia in this position. We aimed to demonstrate that intermittent hypoxia is equally rare in supine and side position. We enrolled 609 term neonates i...

journal_title：Pediatric research

authors： Poets A,Urschitz MS,Poets CF

更新日期：2009-06-01 00:00:00

abstract：:Genetic factors are implicated in pathogenesis of neonatal hyperbilirubinemia. In this nested case-control study, we determined 1) frequency of thymine-adenine (TA)n promoter polymorphism and Gly71Arg mutation in uridine diphosphoglucuronate-glucuronosyltransferase 1A1 (UGT1A1) gene in neonates > or =35-wk gestation p...

journal_title：Pediatric research

authors： Agrawal SK,Kumar P,Rathi R,Sharma N,DAS R,Prasad R,Narang A

更新日期：2009-06-01 00:00:00

abstract：:Necrotizing enterocolitis (NEC) is the most common life-threatening gastrointestinal emergency encountered in the neonatal intensive care unit. Despite advances in neonatal care, NEC remains a leading cause of morbidity and mortality among premature infants. Epidemiologic studies have identified multiple factors that ...

journal_title：Pediatric research

authors： Hunter CJ,Upperman JS,Ford HR,Camerini V

更新日期：2008-02-01 00:00:00

abstract：:We determined whether closing the ductus arteriosus of the fetal lamb several d before birth would cause persistent pulmonary hypertension after birth. Six experimental fetuses who had their ductus arteriosus ligated 3-17 d before delivery, three control fetuses who had sham ligation of the ductus arteriosus 14 d befo...

journal_title：Pediatric research

authors： Morin FC 3rd

更新日期：1989-03-01 00:00:00

abstract：:Endothelin (ET)-1 is a potent vasoconstrictor peptide that modulates basal pulmonary vascular resistance (PVR) in the normal ovine fetus and contributes to high PVR after chronic intrauterine pulmonary hypertension. Although high PVR is present in premature lambs with severe hyaline membrane disease (HMD), whether ET-...

journal_title：Pediatric research

authors： Ivy DD,Parker TA,Kinsella JP,Abman SH

更新日期：1998-08-01 00:00:00

abstract：:Our objective was to determine the quantitative changes of individual triacylglycerol (TG) species in liver and carcass during early postnatal growth. Pregnant rats were killed at d 21 of pregnancy, and neonatal rats were killed at d 3 or 9 after birth. Quantitative changes in fatty acids and TG species of fetal/neona...

journal_title：Pediatric research

authors： Chen ZY,Cunnane SC

更新日期：1992-01-01 00:00:00

abstract：:Human Bifidobacterium sp strain bifidum (B. bifidum) was administered to BALB/c lactating mice (n = 58) and their litters (n = 327 pups) to evaluate the ingested strain's adherent properties and ability to inhibit murine rotavirus (MRV) infection. ELISA and anaerobic bacteriologic techniques were used to measure MRV s...

journal_title：Pediatric research

authors： Duffy LC,Zielezny MA,Riepenhoff-Talty M,Dryja D,Sayahtaheri-Altaie S,Griffiths E,Ruffin D,Barrett H,Rossman J,Ogra PL

更新日期：1994-06-01 00:00:00

abstract：:Sodium deficiency is associated with decreased muscle growth and protein synthesis. We investigated the influence of diet-induced sodium deficiency on the rate and extent of compensatory growth of the right lung after left pneumonectomy in young rats of 83 +/- 1 g body weight. Starting 1 wk before surgery, all rats we...

journal_title：Pediatric research

authors： Gallaher KJ,Wolpert E,Wassner S,Rannels DE

更新日期：1990-11-01 00:00:00

abstract：:BackgroundThe mechanisms underlying aberrant activation of intestinal Toll-like receptor 4 (TLR4) signaling in necrotizing enterocolitis (NEC) remain unclear. In this study, we examined the role of single-immunoglobulin interleukin-1 receptor-related molecule (SIGIRR), an inhibitor of TLR signaling, in modulating expe...

journal_title：Pediatric research

authors： Fawley J,Cuna A,Menden HL,McElroy S,Umar S,Welak SR,Gourlay DM,Li X,Sampath V

更新日期：2018-01-01 00:00:00

abstract：:We studied the mechanisms by which C16:0 lysophosphatidylcholine (LPC) and albumin inhibit the surface activity of calf lung surfactant extract (CLSE) by using a pulsating bubble apparatus with a specialized hypophase exchange system, plus adsorption and Wilhelmy balance measurements. In the absence of inhibitors, CLS...

journal_title：Pediatric research

authors： Holm BA,Wang Z,Notter RH

更新日期：1999-07-01 00:00:00