Seleno compounds and glutathione peroxidase catalyzed decomposition of S-nitrosothiols.

abstract：:Bovine brain smg p25A, a guanine nucleotide-binding protein with a Mr of about 25,000, bound specifically GTP, guanosine 5'-(3-O-thio)triphosphate (GTP gamma S) and GDP. The initial velocities of the binding of GTP gamma S to GDP-bound smg p25A and the dissociation of GDP from this protein increased by decreasing Mg2+...

journal_title：Biochemical and biophysical research communications

authors： Shoji I,Kikuchi A,Kuroda S,Takai Y

更新日期：1989-07-14 00:00:00

abstract：:The DNA segment harboring the promoter region and the exon 1 of the human tyrosinase gene has been cloned and characterized. Sequence analysis reveals the amino-terminal half of tyrosinase molecule including a signal peptide, of which six amino acid residues are not represented in the tyrosinase cDNA, pHT gamma 1 [Shi...

journal_title：Biochemical and biophysical research communications

authors： Takeda A,Tomita Y,Okinaga S,Tagami H,Shibahara S

更新日期：1989-08-15 00:00:00

abstract：:The E. coli ogt O6-alkylguanine-DNA alkyltransferase has two cysteine residues positioned identically with respect to cysteines in the E. coli ada O6-alkylguanine-DNA alkyltransferase. In order to assess their function, these residues were each substituted by a glycine to generate altered forms of the ogt protein. Mut...

journal_title：Biochemical and biophysical research communications

authors： Harris LC,Potter PM,Margison GP

更新日期：1992-08-31 00:00:00

abstract：:Peroxisomes catalyze a number of essential metabolic functions especially related to lipid metabolism. There is increasing evidence suggesting that peroxisomes are also involved in the synthesis of isoprenoids via the mevalonate pathway at least in rat liver. In order to obtain independent evidence for a role of perox...

journal_title：Biochemical and biophysical research communications

authors： Wanders RJ,Romeijn GJ

更新日期：1998-06-29 00:00:00

abstract：:Colorectal cancer is one of the most common malignant tumors worldwide with rising incidence. MicroRNAs are small non-coding RNAs that implicate in multiple physiological or pathological processes. The aberrant expression of miRNA-215 (miR-215) has been illustrated in various types of cancers. However, the expression ...

journal_title：Biochemical and biophysical research communications

authors： Chen Z,Han S,Huang W,Wu J,Liu Y,Cai S,He Y,Wu S,Song W

更新日期：2016-10-21 00:00:00

abstract：:Activin belongs to transforming growth factor (TGF)-β super family of growth and differentiation factors and activin pathway participated in broad range of cell process. Studies elaborated activin pathway maintain pluripotency in human stem cells and suggest that the function of activin/nodal signaling in self-renew w...

journal_title：Biochemical and biophysical research communications

authors： Liu R,Wang JH,Xu C,Sun B,Kang SO

更新日期：2016-10-28 00:00:00

abstract：:While mutation of alpha-synuclein is a cause of autosomal-dominant Parkinson's disease (PD), it is still elusive as to how alpha-synuclein is involved in the pathogenesis of PD. Here, we show that dopamine-dependent accumulation of alpha-synuclein in cultured cells results in apoptosis. Furthermore, activation of insu...

journal_title：Biochemical and biophysical research communications

authors： Kao SY

更新日期：2009-07-31 00:00:00

abstract：:Incubation of rabbit aortic rings with interleukin-1 (100 U/ml) in vitro led to a depressed contractile response to norepinephrine, whether the endothelium was present or not. In both cases norepinephrine-induced contraction was restored in the presence of NG-methyl-L-arginine (300 microM), an inhibitor of nitric oxid...

journal_title：Biochemical and biophysical research communications

authors： Robert R,Chapelain B,Jean T,Néliat G

更新日期：1992-01-31 00:00:00

abstract：:Protein kinase C (PKC) is a family of serine/threonine kinases whose activity is controlled, in part, by phosphorylation on three conserved residues that are located on the catalytic domain of the enzyme, known as the activation-loop, the turn-motif, and the C-terminal hydrophobic-motif sites. Using a panel of phospho...

journal_title：Biochemical and biophysical research communications

authors： Freeley M,Volkov Y,Kelleher D,Long A

更新日期：2005-08-26 00:00:00

abstract：:Thioproline (Thiazolidine-4-carboxylic acid) and proline were nitrosated by stimulated mouse macrophages in vitro. A macrophage cell line (J774.1, 1.0 x 10(6)/well, 1 ml) was incubated with Escherichia coli lipopolysaccharide, interferon-gamma and thioproline (5 mM) or proline (5 mM). After 72 hr incubation at 37 degr...

journal_title：Biochemical and biophysical research communications

authors： Miwa M,Tsuda M,Kurashima Y,Hara H,Tanaka Y,Shinohara K

更新日期：1989-03-15 00:00:00

abstract：:A bank of pTV32 (Tn 917 lacZ) - generated Bacillus subtilis mutants were examined on milk agar for the ability to produce proteases at 48 degrees C. A single mutant, BUL786, was isolated, which could hydrolyze casein after overnight incubation at 48 degrees C. This mutant secreted protease 10 fold more at 48 degrees C...

journal_title：Biochemical and biophysical research communications

authors： Qoronfleh MW,Streips UN

更新日期：1986-07-31 00:00:00

abstract：:Betaine Aldehyde Dehydrogenase (betaine aldehyde: NAD(P)+ oxidoreductase, (E.C. 1.2.1.8; BADH) catalyze the irreversible oxidation of betaine aldehyde (BA) to glycine betaine (GB) and is essential for polyamine catabolism, γ-aminobutyric acid synthesis, and carnitine biosynthesis. GB is an important osmolyte that regu...

journal_title：Biochemical and biophysical research communications

authors： Rosas-Rodríguez JA,Soñanez-Organis JG,Godoy-Lugo JA,Espinoza-Salazar JA,López-Jacobo CJ,Stephens-Camacho NA,González-Ochoa G

更新日期：2017-08-26 00:00:00

abstract：:Acetylation of lysine residues is conserved in all three kingdoms; however, its role in prokaryotes is unknown. Here we demonstrate that acetylation enables the reference bacterium Escherichia coli to withstand environmental stress. Specifically, the bacterium reaches higher cell densities and becomes more resistant t...

journal_title：Biochemical and biophysical research communications

authors： Ma Q,Wood TK

更新日期：2011-07-15 00:00:00

abstract：:Corneal epithelial stem cells are believed to reside in the basal layer of the limbal epithelium, but no definitive cell surface markers have been identified. For keratinocytes, stem/progenitor cells are known to be enriched by cell surface markers, integrin alpha(6) and CD71, as a minor subpopulation which shows high...

journal_title：Biochemical and biophysical research communications

authors： Hayashi R,Yamato M,Saito T,Oshima T,Okano T,Tano Y,Nishida K

更新日期：2008-03-07 00:00:00

abstract：:Lysine-specific methyltransferase Set7/9 (KMT7) belongs to the SET domain family of proteins. Besides the SET domain, Set7/9 also contains a so-called MORN (Membrane Occupation and Recognition Nexus) domain whose function in high eukaryotes is largely unknown. Set7/9 has been shown to specifically methylate both histo...

journal_title：Biochemical and biophysical research communications

authors： Vasileva E,Shuvalov O,Petukhov A,Fedorova O,Daks A,Nader R,Barlev N

更新日期：2020-05-14 00:00:00

abstract：:Oxygen has always been recognized as an essential element of many life forms, initially through its role as a terminal electron acceptor for the energy-generating pathways of oxidative phosphorylation. In 1955, Hayaishi et al. [Mechanism of the pyrocatechase reaction, J. Am. Chem. Soc. 77 (1955) 5450-5451] presented t...

journal_title：Biochemical and biophysical research communications

authors： Sligar SG,Makris TM,Denisov IG

更新日期：2005-12-09 00:00:00

abstract：:Plasma high density lipoprotein (HDL)-cholesterol levels are inversely correlated to the risk of atherosclerotic cardiovascular diseases. Reverse cholesterol transport (RCT) is one of the major protective systems against atherosclerosis, in which HDL particles play a crucial role to carry cholesterol derived from peri...

journal_title：Biochemical and biophysical research communications

authors： Tsubakio-Yamamoto K,Matsuura F,Koseki M,Oku H,Sandoval JC,Inagaki M,Nakatani K,Nakaoka H,Kawase R,Yuasa-Kawase M,Masuda D,Ohama T,Maeda N,Nakagawa-Toyama Y,Ishigami M,Nishida M,Kihara S,Shimomura I,Yamashita S

更新日期：2008-10-24 00:00:00

abstract：:Kruppel-like factor 2 (KLF2) is a crucial anti-angiogenic factor. However, its precise role in hepatic angiogenesis induced by liver sinusoidal endothelial cells (LSECs) remain unclear. This study was aimed to evaluate the effect of KLF2 on angiogenesis of LSECs and to explore the corresponding mechanism. Cultured hum...

journal_title：Biochemical and biophysical research communications

authors： Zeng XQ,Li N,Pan DY,Miao Q,Ma GF,Liu YM,Tseng YJ,Li F,Xu LL,Chen SY

更新日期：2015-09-04 00:00:00

abstract：:Kinetics of permeation through connexin 43-EGFP hemichannels (Cx43-EGFP HCs) were evaluated in divalent cation-free solutions, which enhance HC open probability and thus, allow measurements during initial velocity. Three cations that become fluorescent upon binding to intracellular nucleic acids [ethidium (Etd), propi...

journal_title：Biochemical and biophysical research communications

authors： Orellana JA,Díaz E,Schalper KA,Vargas AA,Bennett MV,Sáez JC

更新日期：2011-06-17 00:00:00

abstract：:We provide the first demonstration for a Na+/Ca2+ exchanger, NCX-1, in the osteoclast. We speculate that by using Na+ exchange, NCX-1 couples H+ extrusion with Ca2+ fluxes during bone resorption. Microspectrofluorimetry of fura-2-loaded osteoclasts revealed a rapid and sustained, but reversible, cytosolic Ca2+ elevati...

journal_title：Biochemical and biophysical research communications

authors： Moonga BS,Davidson R,Sun L,Adebanjo OA,Moser J,Abedin M,Zaidi N,Huang CL,Zaidi M

更新日期：2001-05-18 00:00:00

abstract：:Novel conformation-specific antibodies were raised against a cyclic chimeric dodecapeptidyl multiple antigen peptide (cCD-MAP) constructed with a spacer-armed Gly-Asp dipeptide and two pentapeptides (S(169)-Q(170)-K(171)-E(172)-G(173) of CCR5 and E(179)-A(180)-D(181)-D(182)-R(183) of CXCR4) which are components of the...

journal_title：Biochemical and biophysical research communications

authors： Misumi S,Takamune N,Ido Y,Hayashi S,Endo M,Mukai R,Tachibana K,Umeda M,Shoji S

更新日期：2001-08-03 00:00:00

abstract：:Fluorogenic substrates for endopeptidases are often prepared by attaching fluorophores and quenchers to opposite ends of the peptide substrates. Here, we describe a new approach by incorporating tryptophan and p-nitrophenylalanine into peptides to give fluorogenic substrates composed entirely of alpha-amino acids. Two...

journal_title：Biochemical and biophysical research communications

authors： Wang W,Liang TC

更新日期：1994-06-15 00:00:00

abstract：:We have isolated, in guinea-pig endometrial cells, an estrogen-induced 1.8 kb RNA called gec1. Screening of a guinea-pig genomic library led to identification of gec1 gene consisting of 4 exons and 3 introns. Exon 1 contains the 5'UTR and the ATG initiation codon. A guinea-pig gec1 cDNA was obtained by 5'-RACE. The 35...

journal_title：Biochemical and biophysical research communications

authors： Vernier-Magnin S,Muller S,Sallot M,Radom J,Musard JF,Adami P,Dulieu P,Rémy-Martin JP,Jouvenot M,Fraichard A

更新日期：2001-06-01 00:00:00

abstract：:A comparative study was conducted between the antiherpetic agents 2'-nor-2'-deoxyguanosine (2'NDG) and acyclovir (ACV) with respect to 1) the relative rates of uptake and phosphorylation to the "active" triphosphate species in tissue culture and 2) the in vitro inhibition of viral and cellular DNA polymerases by their...

journal_title：Biochemical and biophysical research communications

authors： Germershausen J,Bostedor R,Field AK,Perry H,Liou R,Bull H,Tolman RL,Karkas JD

更新日期：1983-10-31 00:00:00

abstract：:The lipase from Malassezia globosa (SMG1) was identified to be strictly specific for mono- and diacylglycerol but not triacylglycerol. The crystal structures of SMG1 were solved in the closed conformation, but they failed to provide direct evidence of factors responsible for this unique selectivity. To address this pr...

journal_title：Biochemical and biophysical research communications

authors： Liu L,Gao C,Lan D,Yang B,Wang Y

更新日期：2012-07-27 00:00:00

abstract：:The left-handed Z-DNA form of the short unmodified alternating guanine-cytosine oligonucleotides, 5'-(dGdC)(24) and 5'-(dGdC)(18), was selectively detected under physiological ionic strength and pH conditions using the anionic nickel(II) porphyrin, NiTPPS. No spectroscopic signal was observed for NiTPPS with any right...

journal_title：Biochemical and biophysical research communications

authors： D'Urso A,Choi JK,Shabbir-Hussain M,Ngwa FN,Lambousis MI,Purrello R,Balaz M

更新日期：2010-06-25 00:00:00

abstract：:The effects of substance P on cultured rabbit osteoclasts were investigated. The intracellular Ca(2+) concentration ([Ca(2+)](i)) which was monitored by the microfluorometric technique using fura-2, in osteoclasts elevated by the addition of substance P (0.3-5 microM). The EC(50) value of substance P was about 200 nM....

journal_title：Biochemical and biophysical research communications

authors： Mori T,Ogata T,Okumura H,Shibata T,Nakamura Y,Kataoka K

更新日期：1999-08-27 00:00:00

abstract：:Mutant superoxide dismutase 1 (mSOD1) is often found as aggregates at the outer-membrane of mitochondria in motor neurons of various mouse models and familial amyotrophic lateral sclerosis (f-ALS) patients. It has been postulated that disruption of mitochondrial function by physical association of misfolded mSOD1 aggr...

journal_title：Biochemical and biophysical research communications

authors： Wei R,Bhattacharya A,Chintalaramulu N,Jernigan AL,Liu Y,Van Remmen H,Chaudhuri AR

更新日期：2012-01-27 00:00:00

abstract：:Brush border membrane vesicles (BBMVs) prepared from midguts of Choristoneura fumiferana larvae were pretreated separately with the three CryIA delta-endotoxins from Bacillus thuringiensis subsp. kurstaki HD-1. Crossed affinity immunoelectrophoresis of the solubilized toxin-BBMV complexes, using antibodies raised agai...

journal_title：Biochemical and biophysical research communications

authors： Pang AS

更新日期：1994-03-30 00:00:00

abstract：:alpha-Crystallin, a major eye lens protein, has been shown to function like a molecular chaperone by suppressing the aggregation of other proteins induced by various stress conditions. Ultraviolet (UV) radiation is known to cause structural and functional alterations in the lens macromolecules. Earlier we observed tha...

journal_title：Biochemical and biophysical research communications

authors： Reddy GB,Reddy PY,Suryanarayana P

更新日期：2001-04-06 00:00:00