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Hormonal regulation of serum and endometrial IL-1 alpha, IL-1 beta and IL-1ra: IL-1 endometrial microenvironment of the human embryo at the apposition phase under physiological and supraphysiological steroid level conditions.

Abstract：

:We have investigated serum and intracavitary levels of IL-1 alpha, IL-1 beta and IL-1ra from agonadal women undergoing mock cycles (n = 20) of oocyte donation as a clinical model of controlled hormonal stimulation. Further, we compared the intracavitary IL-1 alpha, IL-1 beta and IL-1ra levels in the microenvironment of the human embryo at the apposition phase, day 5 after progesterone (P) administration using two different clinical models: oocyte donation (n = 20) which provides physiological steroid levels and a higher implantation rate per embryo, and in vitro fertilization (n = 6) with supraphysiological hormonal levels and a lower implantation rate.

journal_name

J Reprod Immunol

journal_title

Journal of reproductive immunology

authors

Simón C,Mercader A,Frances A,Gimeno MJ,Polan ML,Remohí J,Pellicer A

doi

10.1016/0165-0378(96)00982-5

subject

Has Abstract

pub_date

1996-10-01 00:00:00

pages

165-84

issue

3

eissn

0165-0378

issn

1872-7603

pii

0165037896009825

journal_volume

31

pub_type

杂志文章

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