当前位置： SCI文献检索 > JOURNAL OF REPRODUCTIVE IMMUNOLOGY期刊下所有文献 > Studies on the subunit and polypeptide structure of a polymeric form of pregnancy-specific beta 1-glycoprotein.

Studies on the subunit and polypeptide structure of a polymeric form of pregnancy-specific beta 1-glycoprotein.

Abstract：

:The structure of a high-molecular-weight form of Pregnancy-Specific beta 1-Glycoprotein designated PSB1G-I that had been previously isolated from maternal serum was studied by gel chromatography in guanidine hydrochloride dissociating solvent. Evidence was obtained that subunits of identical size (bonded together non-covalently) but of differing polypeptide compositions constitute the PSB1G-I molecule. The subunits of PSB1G-I have been designated alpha and beta subunits. Reduction of PSB1G-I results in an intact alpha chain and two beta chains (beta 1 and beta 2) that are linked in the parent beta subunit by covalent bonds. The collective molecular weights of the alpha, beta 1 and beta 2 chains are equal to 97 800 which is assumed to represent the 'true' molecular weight of 'native' serum PSB1G.

journal_name

J Reprod Immunol

journal_title

Journal of reproductive immunology

authors

Griffiths BW,Godard A

doi

10.1016/0165-0378(81)90017-6

subject

Has Abstract

pub_date

1981-06-01 00:00:00

pages

131-6

issue

2

eissn

0165-0378

issn

1872-7603

pii

0165-0378(81)90017-6

journal_volume

3

pub_type

杂志文章

相关文献

JOURNAL OF REPRODUCTIVE IMMUNOLOGY文献大全
  • Demonstration of the low affinity alpha subunit of the granulocyte-macrophage colony-stimulating factor receptor (GM-CSF-R alpha) on human trophoblast and uterine cells.

    abstract：:Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a classical haematopoietic cytokine which has also been implicated in placental growth and development. In this study we have performed a detailed immunohistological localization of the low affinity GM-CSF receptor (GM-CSF-R alpha) in human first trimester i...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(94)90037-x

    authors： Jokhi PP,King A,Jubinsky PT,Loke YW

    更新日期：1994-03-01 00:00:00

  • Risk factors for pregnancy failure in patients with antiphospholipid antibody positivity and prior pregnancy losses: A retrospective study.

    abstract：OBJECTIVES:To analyze the risk factors associated with pregnancy failure in patients with positive antiphospholipid antibodies (aPL) and prior pregnancy losses, with or without a diagnosis of antiphospholipid syndrome. METHODS:We retrospectively reviewed the medical records of all the pregnant patients with positive a...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2020.103171

    authors： Duan H,Li X,Liu C,Ge Y,Deng X

    更新日期：2020-09-01 00:00:00

  • Complement component deposition in uteroplacental (spiral) arteries in normal human pregnancy.

    abstract：:There is conflicting evidence for the deposition of complement in spiral arteries in normal and abnormal human pregnancies. The immunogold silver staining (IGSS) technique was used to investigate the distribution of C1q, C3d, C4, C6 and C9 within the spiral arteries of formalin-fixed normal pregnancy hysterectomy spec...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(87)90040-4

    authors： Wells M,Bennett J,Bulmer JN,Jackson P,Holgate CS

    更新日期：1987-10-01 00:00:00

  • Peritoneal fluid from endometriosis patients switches differentiation of monocytes from dendritic cells to macrophages.

    abstract：:Immunological abnormalities of cell-mediated and humoral immunity might be associated with the pathogenesis of endometriosis. This study has examined the effects of peritoneal fluid obtained from patients with endometriosis (ePF) on the phenotypic characteristics of macrophages and dendritic cells (DCs) derived from m...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2007.03.013

    authors： Na YJ,Jin JO,Lee MS,Song MG,Lee KS,Kwak JY

    更新日期：2008-01-01 00:00:00

  • Progesterone and estradiol exert an inhibitory effect on the production of anti-inflammatory cytokine IL-10 by activated MZ B cells.

    abstract：:The main message of this work is the fact that female sex hormones, progesterone and estradiol, whose levels significantly rise during pregnancy, inhibit the production of anti-inflammatory cytokine IL-10 with no apparent effect on pro-inflammatory cytokine TNF-α by activated MZ B cells. This is an important piece of ...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2016.05.008

    authors： Bommer I,Muzzio DO,Zygmunt M,Jensen F

    更新日期：2016-08-01 00:00:00

  • NK cell subsets in idiopathic recurrent miscarriage and renal transplant patients.

    abstract：:The present review article compares NK cell subsets and cytokine patterns determined in the peripheral blood as well as results of functional in-vitro assays using peripheral NK cells of idiopathic recurrent miscarriage (iRM) patients with corresponding results obtained in female healthy controls and female renal tran...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jri.2020.103098

    authors： Toth B,Zhu L,Karakizlis H,Weimer R,Morath C,Opelz G,Kuon RJ,Daniel V

    更新日期：2020-04-01 00:00:00

  • Quantitative comparison of stem cell marker-positive cells in fetal and term human amnion.

    abstract：:Scattered in the amniotic epithelium of the human term placenta are pluripotent stem cell marker-positive cells. Unlike other parts of the placenta, amniotic epithelial (AE) cells are derived from pluripotent epiblasts. It is hypothesized that most epiblast-derived fetal AE cells are positive for stem cell markers at ...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2009.02.007

    authors： Izumi M,Pazin BJ,Minervini CF,Gerlach J,Ross MA,Stolz DB,Turner ME,Thompson RL,Miki T

    更新日期：2009-07-01 00:00:00

  • The role of visfatin (PBEF/Nampt) in pregnancy complications.

    abstract：:Visfatin (PBEF/Nampt) is an adipocytokine that exerts pleiotropic effects within the human body, particularly affecting its metabolism and immunity. Visfatin was originally identified as being secreted by peripheral blood lymphocytes acting as a pre-B-cell colony-enhancing factor (PBEF). However, it was subsequently r...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jri.2015.09.004

    authors： Pavlová T,Novák J,Bienertová-Vašků J

    更新日期：2015-11-01 00:00:00

  • Indomethacin blocks the immunosuppressive activity of rat testicular macrophages cultured in vitro.

    abstract：:Macrophages are a prominent resident cell type in the interstitial tissue of the testis in several mammalian species. This presence in an immunologically-privileged site prompted an investigation of their ability to initiate and regulate lymphocyte proliferation in vitro. Isolated rat peripheral blood lymphocytes (PBL...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(95)91391-q

    authors： Kern S,Maddocks S

    更新日期：1995-03-01 00:00:00

  • In vitro production of human anti-sperm antibodies: effect of an oligoclonal antibody (F6) on sperm-egg interaction.

    abstract：:A method has been developed to establish lines of transformed lymphocytes able to produce in vitro the same anti-sperm antibodies as those naturally occurring in immuno-infertile individuals. We utilized lymphocytes from a male donor whose serum contained anti-sperm antibodies of the IgG class up to the dilution 1:10,...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(95)00939-i

    authors： Fusi FM,Besuschio F,De Santis L,Lorenzetti I,Ferrari A

    更新日期：1995-07-01 00:00:00

  • Colony Stimulating Factors 1, 2, 3 and early pregnancy steps: from bench to bedside.

    abstract：:Reproductive immunology applies general immunology principles to specialised targets, reproduction and development. The involvement of colony-stimulating factors (CSFs) in reproduction illustrates this. The CSF family includes CSF-1 or macrophage CSF (M-CSF), CSF-2 or granulocyte macrophage CSF (GM-CSF), and CSF-3 or ...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jri.2015.01.005

    authors： Rahmati M,Petitbarat M,Dubanchet S,Bensussan A,Chaouat G,Ledee N

    更新日期：2015-06-01 00:00:00

  • Reduction in uterine intra-epithelial lymphocytes during early gestation in pigs.

    abstract：:The numbers of intra-epithelial lymphocytes per 5 mm of uterine epithelium were counted in cyclic (n = 18) and pregnant (n = 18) gilts on days 10, 13, 16 and 19 postestrus. In cyclic animals these cells increased (P less than 0.01) from 26.4 +/- 1.1 per 5 mm at the mid-luteal phase (day 10) to 47.7 +/- 1.5 per 5 mm at...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(88)90034-4

    authors： King GJ

    更新日期：1988-10-01 00:00:00

  • Acute systemic immune activation following vaginal exposure to staphylococcal enterotoxin B--implications for menstrual shock.

    abstract：:Menstrual toxic shock syndrome (mTSS) is an acute systemic inflammatory disease associated with the superantigenic exotoxin, toxic shock syndrome toxin (TSST)-1, produced by Staphylococcus aureus and the use of high absorbency tampons. Even though S. aureus is capable of elaborating several other superantigenic exotox...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2006.06.007

    authors： Rajagopalan G,Smart MK,Murali N,Patel R,David CS

    更新日期：2007-02-01 00:00:00

  • Association of a maternal CD14 -159 gene polymorphism with preterm premature rupture of membranes and spontaneous preterm birth in multi-fetal pregnancies.

    abstract：:CD14, the major receptor for bacterial lipopolysaccharide (LPS) as well as other microbial antigens, is a component of the innate immune system. We hypothesized that a single nucleotide C>T polymorphism at position -159 in the CD14 gene that results in elevated CD14 production would influence susceptibility to preterm...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2005.12.002

    authors： Kalish RB,Vardhana S,Normand NJ,Gupta M,Witkin SS

    更新日期：2006-06-01 00:00:00

  • High serum IGF-1 levels are associated with pregnancy loss following frozen-thawed euploid embryo transfer cycles.

    abstract：:An elevated level of insulin growth factor (IGF-1) in rat uterine fluid has been shown to exert detrimental effects of embryo development possibly leading to an increase in pregnancy loss. Interestingly, the administration of somatostatin to rats undergoing superovulation reduced IGF-1 levels in uterine luminal fluid ...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2018.03.002

    authors： Irani M,Nasioudis D,Witkin SS,Gunnala V,Spandorfer SD

    更新日期：2018-06-01 00:00:00

  • Identification and characterization of human acrosomal antigen defined by a monoclonal antibody with blocking effect on in vitro fertilization.

    abstract：:A monoclonal anti-human sperm antibody (Mab 1A1) has been produced by fusion of myeloma cells with splenocytes from a BALB/c mouse immunized with in vitro capacitated human spermatozoa. Immunofluorescence studies with Mab 1A1 show that it recognizes an antigen(s) (Ag 1A1) which is located in the acrosome of human sper...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(91)90039-s

    authors： Dubova-Mihailova M,Mollova M,Ivanova M,Kehayov I,Kyurkchiev S

    更新日期：1991-04-01 00:00:00

  • Serum but not follicular fluid cytokine levels are increased in stimulated versus natural cycle IVF: a multiplexed assay study.

    abstract：:Throughout follicular growth the number of immune cells increases, enhanced under stimulation with exogenous gonadotropins. This treatment, however, may adversely influence folliculogenesis and negatively affect oocyte quality through modifications in the follicular concentrations of cytokines released by these immune...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2014.06.003

    authors： Bersinger NA,Kollmann Z,Von Wolff M

    更新日期：2014-12-01 00:00:00

  • Serum leptin level in women with unexplained infertility.

    abstract：INTRODUCTION:The aim of this study was to compare serum levels of leptin in women with unexplained infertility with fertile subjects. MATERIAL AND METHOD:Serum leptin levels of 27 infertile and 30 fertile women on day 3 of the menstrual cycle were assessed and compared in this prospective age and body mass index (BMI)...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2007.04.001

    authors： Demir B,Guven S,Guven ES,Atamer Y,Gunalp GS,Gul T

    更新日期：2007-10-01 00:00:00

  • Adenovirus mediated CTLA4Ig transgene therapy alleviates abortion by inhibiting spleen lymphocyte proliferation and regulating apoptosis in the feto-placental unit.

    abstract：:Pregnancy is thought to be a state of immunological tolerance. The mechanisms underlying this phenomenon are still poorly understood. In our previous study, adenovirus mediated CTLA4Ig transgene (Ad-CTLA4Ig) therapy was demonstrated to improve pregnancy outcome in an abortion-prone mouse model by skewing the Th2/Th1 c...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2013.01.002

    authors： Li W,Li B,Li S

    更新日期：2013-04-01 00:00:00

  • Secondary recurrent miscarriage is associated with previous male birth.

    abstract：:Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor h...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2010.10.004

    authors： Ooi PV,Russell N,O'Donoghue K

    更新日期：2011-01-01 00:00:00

  • Immunomodulatory effects of Salvianolic acid B in a spontaneous abortion mouse model.

    abstract：:Pregnancy is a kind of natural immune tolerance. Immune factors play an important role in recurrent spontaneous abortion and repeated implantation failure. Salvianolic acid B (SalB) has anti-tumor, anti-inflammatory, anti-oxidation and immunomodulatory functions. However, there are few reports on the relationship betw...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2019.103075

    authors： Wang J,Liu C,Que W,Fujino M,Tong G,Yan H,Li XK

    更新日期：2020-02-01 00:00:00

  • Pravastatin prevents miscarriages in antiphospholipid antibody-treated mice.

    abstract：:Miscarriages in patients with antiphospholipid (aPL) antibodies have been attributed to thrombosis of placental vessels. However, we have shown that inflammation plays a crucial role in fetal injury. We identified tissue factor (TF), the major cellular activator of the coagulation cascade, as a key mediator in inflamm...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2009.03.003

    authors： Girardi G

    更新日期：2009-11-01 00:00:00

  • Expression of retrovirus-related antigen in pregnancy. I. Antigens cross-reacting with simian retroviruses in human foetal tissues and cord blood lymphocytes.

    abstract：:Antisera to Mason-Pfizer or Baboon Endogenous Virus possessed complement-dependent cytotoxicity for cell lines chronically infected with these viruses, with some degree of cross-reaction. When appropriately absorbed with virus-free cells, the antisera were not cytotoxic for lymphocytes of adult males but lysed lymphoc...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(81)90001-2

    authors： Thiry L,Sprecher-Goldberger S,Hard RC,Bossens M,Neuray F

    更新日期：1981-03-01 00:00:00

  • Isolation of a sperm autoantigen from the kidneys of vasectomized rabbits.

    abstract：:The rabbit sperm membrane autoantigen, RSA-1, has been isolated from the kidneys of bilaterally vasectomized rabbits. Using detergent extraction the IgG-RSA-1 complex in the kidney was isolated first on an anti-IgG immunocolumn. The eluted IgG-RSA-1 complex was then applied to an anti-sperm autoantibody column which b...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(84)90006-8

    authors： O'Rand MG,Porter JP,Alexander NJ

    更新日期：1984-02-01 00:00:00

  • Characteristics of peripheral blood NK and NKT-like cells in euthyroid and subclinical hypothyroid women with thyroid autoimmunity experiencing reproductive failure.

    abstract：:Thyroid autoimmunity (TAI) appears to play a crucial role in female infertility, recurrent pregnancy loss and IVF failure. Thyroid autoantibodies against thyroid peroxidase and thyroglobulin have been shown to represent an independent risk factor for infertility and miscarriage. Moreover, thyroxin hormone administrati...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2017.09.008

    authors： Miko E,Meggyes M,Doba K,Farkas N,Bogar B,Barakonyi A,Szereday L,Szekeres-Bartho J,Mezosi E

    更新日期：2017-11-01 00:00:00

  • Delineation of epitopes on porcine zona pellucida relevant for binding of sperm to oocyte using monoclonal antibodies.

    abstract：:Seven monoclonal antibodies (MAs) generated against porcine zona pellucida glycoprotein, ZP3 (comprising both ZP3 alpha and ZP3 beta) were characterized for their specificities to ZP3 alpha (MA 7 and MA 28) or ZP3 beta (MA 1, MA 2, MA 10, MA 27 and MA 30) and their relative affinities in competitive ELISA. Among the s...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(93)90047-l

    authors： Bagavant H,Yurewicz EC,Sacco AG,Talwar GP,Gupta SK

    更新日期：1993-04-01 00:00:00

  • Sperm/DNA interaction: integration of foreign DNA sequences in the mouse sperm genome.

    abstract：:Foreign DNA is spontaneously taken up by mouse epididymal sperm cells and is further internalized into nuclei. The interaction and/or internalization of the exogenous DNA triggers the activation of sperm endogenous nucleases which mediate rearrangements of the internalized DNA. Foreign DNA sequences are found to be ti...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章,评审

    doi：10.1016/s0165-0378(98)00058-8

    authors： Magnano AR,Giordano R,Moscufo N,Baccetti B,Spadafora C

    更新日期：1998-12-01 00:00:00

  • The effect of neonatal thymectomy on the induction of autoimmune orchitis in rats.

    abstract：:The objective of these experiments was to determine the effects of neonatal thymectomy on the induction of experimental autoimmune orchitis in inbred rats of the Fischer 344 and Lewis strains. It was found that thymectomy alone in Lewis rats, and thymectomy followed by immunization with testicular extract in both Lewi...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(79)90001-9

    authors： Lipscomb HL,Gardner PJ,Sharp JG

    更新日期：1979-12-01 00:00:00

  • Antisperm autoantibody responses to vasectomy and vasovasostomy in Fischer and Lewis rats.

    abstract：:Antisperm autoantibodies were studied in Fischer and Lewis strains of rats after either vasectomy, vasectomy followed one month later by vasovasostomy, or sham operations. The time course of antibody response to sperm protein autoantigens was assayed by Western blot analysis of sera obtained at intervals up to 3 month...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(94)00904-l

    authors： Flickinger CJ,Howards SS,Bush LA,Baker LA,Herr JC

    更新日期：1995-02-01 00:00:00

  • Expression of indoleamine 2,3-dioxygenase in the rhesus monkey and common marmoset.

    abstract：:Indoleamine 2,3-dioxygenase (IDO) catalyzes the initial and rate-limiting step of tryptophan degradation along the kynurenine pathway, and is hypothesized to limit tryptophan availability at embryo implantation and prevent maternal T cell activation at the maternal-fetal interface. To determine if nonhuman primates ar...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2008.03.005

    authors： Drenzek JG,Breburda EE,Burleigh DW,Bondarenko GI,Grendell RL,Golos TG

    更新日期：2008-07-01 00:00:00