当前位置： SCI文献检索 > JOURNAL OF REPRODUCTIVE IMMUNOLOGY期刊下所有文献 > Isolation of a sperm autoantigen from the kidneys of vasectomized rabbits.

Isolation of a sperm autoantigen from the kidneys of vasectomized rabbits.

Abstract：

:The rabbit sperm membrane autoantigen, RSA-1, has been isolated from the kidneys of bilaterally vasectomized rabbits. Using detergent extraction the IgG-RSA-1 complex in the kidney was isolated first on an anti-IgG immunocolumn. The eluted IgG-RSA-1 complex was then applied to an anti-sperm autoantibody column which bound the RSA-1, displacing the kidney anti-RSA-1 IgG. RSA-1 was subsequently eluted from the anti-sperm autoantibody column. This is the first identification of a known sperm antigen in the kidneys of vasectomized animals. Furthermore, this methodology should be applicable to the isolation of antigens from a variety of other tissues and immune complexes.

journal_name

J Reprod Immunol

journal_title

Journal of reproductive immunology

authors

O'Rand MG,Porter JP,Alexander NJ

doi

10.1016/0165-0378(84)90006-8

subject

Has Abstract

pub_date

1984-02-01 00:00:00

pages

121-8

issue

2

eissn

0165-0378

issn

1872-7603

pii

0165-0378(84)90006-8

journal_volume

6

pub_type

杂志文章

相关文献

JOURNAL OF REPRODUCTIVE IMMUNOLOGY文献大全
  • Differential actions of progesterone and cortisol on lymphocyte and monocyte interaction during lymphocyte activation--relevance to immunosuppression in pregnancy.

    abstract：:Progesterone and glucocorticoids share important anti-inflammatory and immunosuppressive properties. Both hormones have potent anti-proliferative effects in MLR, mitogen activation and cytotoxic T-cell generation. We investigated the cellular target of this in vitro anti-proliferative activity by comparing the effects...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(83)90237-1

    authors： Stites DP,Bugbee S,Siiteri PK

    更新日期：1983-07-01 00:00:00

  • Intrauterine infusion of bacterial lipopolysaccharide (LPS) prior to mating has no adverse effect on fertility, fetal survival and fetal development.

    abstract：:Lipopolysaccharide (LPS, endotoxin) is a component of the cell wall of gram-negative bacteria and a potent inducer of severe inflammatory reactions. In mice, systemically administered LPS induces fetal resorption and increases fetal mortality. However, effects of intrauterine LPS on fertility, fetal survival and devel...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/s0165-0378(98)00078-3

    authors： Tuo W,Ott TL,Liu S,Bazer FW

    更新日期：1999-01-01 00:00:00

  • The placental regulatory factor involved in the asymmetric IgG antibody synthesis responds to IL-6 features.

    abstract：:Pregnancy success is attributed to the joint action of several factors such as regulatory placental molecules and components of the mother's immune system, among others. Asymmetrical glycosilated and functionally univalent IgG antibodies are suggested to influence the immune balance between the mother and foetus, play...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/s0165-0378(00)00074-7

    authors： Gutiérrez G,Malan Borel I,Margni RA

    更新日期：2001-01-01 00:00:00

  • Pravastatin prevents miscarriages in antiphospholipid antibody-treated mice.

    abstract：:Miscarriages in patients with antiphospholipid (aPL) antibodies have been attributed to thrombosis of placental vessels. However, we have shown that inflammation plays a crucial role in fetal injury. We identified tissue factor (TF), the major cellular activator of the coagulation cascade, as a key mediator in inflamm...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2009.03.003

    authors： Girardi G

    更新日期：2009-11-01 00:00:00

  • Fibrinogen, an endogenous ligand of Toll-like receptor 4, activates monocytes in pre-eclamptic patients.

    abstract：:Pre-eclampsia (PE) remains the leading cause of pregnancy-associated mortality and morbidity, urging the need for a better understanding of its aetiology and pathophysiological progression. A key characteristic of PE is a systemic, exaggerated, inflammatory condition involving abnormal cytokine levels in serum, altere...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2014.02.004

    authors： Al-ofi E,Coffelt SB,Anumba DO

    更新日期：2014-06-01 00:00:00

  • Monoclonal antibodies affecting sperm-zona binding and/or zona-induced acrosome reaction.

    abstract：:The majority of anti-sperm monoclonal antibodies which were shown to inhibit in vitro fertilization in our laboratory react with antigens in the acrosomal region of spermatozoa. To elucidate the mechanism of human and/or mouse fertilization inhibition, the effects of these antibodies on mouse sperm-zona binding and mo...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(92)90023-w

    authors： Fann CH,Lee CY

    更新日期：1992-03-01 00:00:00

  • Antibody reactivity with porcine zona pellucida.

    abstract：:A comparative study on anti-zona antibody activities in the sera from clinically defined categories of patients registered at the WHO Reference Bank for Reproductive Immunology was performed at five different laboratories with different detection methods. Considerably higher incidences of positive reactions were detec...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(85)90008-7

    authors： Mori T,Kamada M,Hasebe H,Irahara M,Shivers A,Czuppon AB,Mettler L,Mathur S,Dunbar BS

    更新日期：1985-12-01 00:00:00

  • Reflections upon immunological mechanisms involved in fertility, pregnancy and parasite infections.

    abstract：:During a pregnancy, the mother accepts her semi-allogeneic fetus with no signs of immunological rejection. Therefore, some modulation of the maternal immune system must occur. Similarly, changes in the host's immune system occurs during infections with parasites. In a study conducted in an endemic area in Bolivia, it ...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jri.2019.08.001

    authors： Persson G,Ekmann JR,Hviid TVF

    更新日期：2019-11-01 00:00:00

  • Prostaglandin-E2 released by pre-implantation human conceptuses.

    abstract：:This work investigates the production of prostaglandin E2 (PGE2), a well known modulator for the suppression of immune cells, by pre-implantation human conceptuses from the 4-cell stage to the hatched blastocyst and by cumulus oophorus cells, these being obtained from an IVF/ET program. Cumulus cell complexes cultured...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(90)90041-4

    authors： Holmes PV,Sjögren A,Hamberger L

    更新日期：1990-03-01 00:00:00

  • Bone-marrow origin of endometrial granulocytes in the early human placental bed.

    abstract：:A large number of cells in the first trimester human placenta have been shown to express leucocyte-common antigen by the use of a monoclonal antibody in an immunoperoxidase technique. The distribution of endometrial granulocytes in the decidua of early pregnancy indicates that a large proportion of these cells bear th...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(83)90247-4

    authors： Bulmer JN,Sunderland CA

    更新日期：1983-11-01 00:00:00

  • Autoantibody screening for infertility: explaining the unexplained?

    abstract：:Several laboratories currently offer panels of serum autoantibody assays to screen women with unexplained infertility and those undergoing in vitro fertilization (IVF). Offering these tests implies that they have predictive value for the outcome of proposed infertility treatments such that the results of the testing w...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章,评审

    doi：10.1016/s0165-0378(97)00027-2

    authors： Hatasaka HH,Branch DW,Kutteh WH,Scott JR

    更新日期：1997-09-01 00:00:00

  • The lymphocyte and macrophage profile in the pancreas and spleen of NOD mice: percentage of interleukin-2 and prolactin receptors on immunocompetent cell subsets.

    abstract：:The NOD mouse is a model for autoimmune diabetes that develops symptoms similar to Type I diabetes. The incidence of diabetes is greater in females but the degree of insulitis is comparable in both sexes. The purpose of this study was to assess the populations of lymphocytes and macrophages in the pancreas and spleen ...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/s0165-0378(96)00986-2

    authors： Hawkins TA,Gala RR,Dunbar JC

    更新日期：1996-11-01 00:00:00

  • Expression and localization of cell adhesion molecules in human fetal membranes during parturition.

    abstract：:There is increasing evidence to support the view that human parturition represents an inflammatory process. We have previously demonstrated that parturition is associated with leukocyte invasion and pro-inflammatory cytokine production in the cervix and myometrium. Furthermore, we have shown that several cell adhesion...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2004.04.003

    authors： Osman I,Crawford M,Jordan F,Young A,Norman J,Thomson A

    更新日期：2004-08-01 00:00:00

  • Spliceosome protein EFTUD2 is upregulated in the trophoblast of spontaneous miscarriage and hydatidiform mole.

    abstract：BACKGROUND:Elongation factor Tu GTP binding domain containing 2 (EFTUD2) is an alternative splicing factor that modulates cell differentiation and activation processes. EFTUD2 is known to modulate immune responses and mutation of the EFTUD2-gene lead to fetal malformation. Little is known about its expression and role ...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2020.103149

    authors： Löb S,Vattai A,Kuhn C,Schmoeckel E,Mahner S,Wöckel A,Kolben T,Szekeres-Bartho J,Jeschke U,Vilsmaier T

    更新日期：2020-08-01 00:00:00

  • Antisperm autoantibody responses to vasectomy and vasovasostomy in Fischer and Lewis rats.

    abstract：:Antisperm autoantibodies were studied in Fischer and Lewis strains of rats after either vasectomy, vasectomy followed one month later by vasovasostomy, or sham operations. The time course of antibody response to sperm protein autoantigens was assayed by Western blot analysis of sera obtained at intervals up to 3 month...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(94)00904-l

    authors： Flickinger CJ,Howards SS,Bush LA,Baker LA,Herr JC

    更新日期：1995-02-01 00:00:00

  • Characteristics of peripheral blood NK and NKT-like cells in euthyroid and subclinical hypothyroid women with thyroid autoimmunity experiencing reproductive failure.

    abstract：:Thyroid autoimmunity (TAI) appears to play a crucial role in female infertility, recurrent pregnancy loss and IVF failure. Thyroid autoantibodies against thyroid peroxidase and thyroglobulin have been shown to represent an independent risk factor for infertility and miscarriage. Moreover, thyroxin hormone administrati...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2017.09.008

    authors： Miko E,Meggyes M,Doba K,Farkas N,Bogar B,Barakonyi A,Szereday L,Szekeres-Bartho J,Mezosi E

    更新日期：2017-11-01 00:00:00

  • Epidemiological studies on primipaternity and immunology in preeclampsia--a statement after twelve years of workshops.

    abstract：:Hypertensive disorders of pregnancy (HDP) represent 10% of human births globally and the major complication preeclampsia has a 3-5% prevalence. The etiology of HDP remains uncertain; however, major advances have been made over the last 25 years. The Seventh International Workshop on Reproductive Immunology, Immunologi...

    journal_title：Journal of reproductive immunology

    pub_type： 历史文章,杂志文章,评审

    doi：10.1016/j.jri.2011.02.003

    authors： Robillard PY,Dekker G,Chaouat G,Hulsey TC,Saftlas A

    更新日期：2011-05-01 00:00:00

  • Immunomodulatory effects of Salvianolic acid B in a spontaneous abortion mouse model.

    abstract：:Pregnancy is a kind of natural immune tolerance. Immune factors play an important role in recurrent spontaneous abortion and repeated implantation failure. Salvianolic acid B (SalB) has anti-tumor, anti-inflammatory, anti-oxidation and immunomodulatory functions. However, there are few reports on the relationship betw...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2019.103075

    authors： Wang J,Liu C,Que W,Fujino M,Tong G,Yan H,Li XK

    更新日期：2020-02-01 00:00:00

  • Galectins in angiogenesis: consequences for gestation.

    abstract：:Members of the galectin family have been shown to exert several roles in the context of reproduction. They contribute to placentation, maternal immune regulation and facilitate angiogenesis encompassing decidualisation and placenta formation during pregnancy. In the context of neo-vascularisation, galectins have been ...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jri.2014.12.001

    authors： Blois SM,Conrad ML,Freitag N,Barrientos G

    更新日期：2015-04-01 00:00:00

  • Potential contraceptive use of epididymal proteins: evidence for the participation of specific antibodies against rat epididymal protein DE in male and female fertility inhibition.

    abstract：:Previous studies in our laboratory indicated that immunization of male and female Wistar and Lewis rats with epididymal protein DE, resulted in the development of anti-DE antibodies in over 90% of the animals, with a significant and reversible reduction of fertility. In the present study, ELISA assays performed to ana...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(95)00927-d

    authors： Perez Martinez S,Conesa D,Cuasnicú PS

    更新日期：1995-05-01 00:00:00

  • Colony Stimulating Factors 1, 2, 3 and early pregnancy steps: from bench to bedside.

    abstract：:Reproductive immunology applies general immunology principles to specialised targets, reproduction and development. The involvement of colony-stimulating factors (CSFs) in reproduction illustrates this. The CSF family includes CSF-1 or macrophage CSF (M-CSF), CSF-2 or granulocyte macrophage CSF (GM-CSF), and CSF-3 or ...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jri.2015.01.005

    authors： Rahmati M,Petitbarat M,Dubanchet S,Bensussan A,Chaouat G,Ledee N

    更新日期：2015-06-01 00:00:00

  • Indomethacin blocks the immunosuppressive activity of rat testicular macrophages cultured in vitro.

    abstract：:Macrophages are a prominent resident cell type in the interstitial tissue of the testis in several mammalian species. This presence in an immunologically-privileged site prompted an investigation of their ability to initiate and regulate lymphocyte proliferation in vitro. Isolated rat peripheral blood lymphocytes (PBL...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(95)91391-q

    authors： Kern S,Maddocks S

    更新日期：1995-03-01 00:00:00

  • Quantitative comparison of stem cell marker-positive cells in fetal and term human amnion.

    abstract：:Scattered in the amniotic epithelium of the human term placenta are pluripotent stem cell marker-positive cells. Unlike other parts of the placenta, amniotic epithelial (AE) cells are derived from pluripotent epiblasts. It is hypothesized that most epiblast-derived fetal AE cells are positive for stem cell markers at ...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2009.02.007

    authors： Izumi M,Pazin BJ,Minervini CF,Gerlach J,Ross MA,Stolz DB,Turner ME,Thompson RL,Miki T

    更新日期：2009-07-01 00:00:00

  • Proacrosin binding protein: immunocomparative studies in boar, bovine, hamster, human and ram.

    abstract：:The cross reactivities of acidic extracts from boar, bovine, hamster, human and ram spermatozoa to a polyclonal antibody of the boar proacrosin binding protein has been investigated. The pH 3.0 extracts of the washed spermatozoa from each species were subjected to Western blot analysis using a polyclonal antibody deve...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/0165-0378(92)90033-z

    authors： Yi LS,Polakoski KL

    更新日期：1992-04-01 00:00:00

  • Antenatal inflammation and gestational diabetes mellitus risk among pregnant African-American women.

    abstract：:Although inflammation is associated with risk of gestational diabetes mellitus (GDM), little is known if there is an association between inflammation and GDM in African-American women, a group at higher risk for GDM complications. In the present study, we aimed to determine if selected inflammatory cytokines (i.e. TNF...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2016.03.005

    authors： Bossick AS,Peters RM,Burmeister C,Kakumanu N,Shill JE,Cassidy-Bushrow AE

    更新日期：2016-06-01 00:00:00

  • Priming of peripheral monocytes with prolactin (PRL) sensitizes IFN-gamma-mediated indoleamine 2,3-dioxygenase (IDO) expression without affecting IFN-gamma signaling.

    abstract：:Prolactin (PRL) was originally identified by its ability to stimulate mammary development and lactation, and its essential roles other than lactation have recently been implicated in female reproduction. However, little is known about PRL-mediated events in pregnancy. The tryptophan catabolism enzyme indoleamine 2,3-d...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2007.08.003

    authors： Kawaguchi R,Shimokawa T,Umehara N,Nunomura S,Tanaka T,Ra C

    更新日期：2008-04-01 00:00:00

  • Interleukin-18 and interleukin-12 in maternal serum and spontaneous preterm delivery.

    abstract：INTRODUCTION:Mice disrupted for the interleukin (IL)-18 gene appear more disposed to preterm delivery (PTD) induced by inflammation. A synergy between IL-18 and IL-12 has been suggested. The objective of this study was to investigate a possible relation between human maternal serum levels of IL-18, IL-12 and spontaneou...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2007.07.002

    authors： Ekelund CK,Vogel I,Skogstrand K,Thorsen P,Hougaard DM,Langhoff-Roos J,Jacobsson B

    更新日期：2008-04-01 00:00:00

  • Local and systemic levels of cytokines and danger signals in endometriosis-affected women.

    abstract：:Endometriosis is a prevalent gynaecological disorder with a still unclear pathogenesis. So far inflammatory mechanisms are associated with disease progression and critical reviews have discussed the so-called 'danger theory' related to endometriosis. Hence, we performed immunoassays to evaluate whether local inflammat...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2018.07.006

    authors： Jaeger-Lansky A,Schmidthaler K,Kuessel L,Gstöttner M,Waidhofer-Söllner P,Zlabinger GJ,Wenzl R,Eiwegger T

    更新日期：2018-11-01 00:00:00

  • Antiretroviral therapy-associated modulation of Th1 and Th2 immune responses in HIV-infected pregnant women.

    abstract：:A successful pregnancy is characterised by an increase in Th2 cytokines and suppression of Th1 cytokine production. A Th1 to Th2 cytokine shift is also observed in the disease progression of HIV infection. Highly active antiretroviral therapy (HAART) suppresses HIV viremia, increases CD4+ cell counts and counteracts t...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章

    doi：10.1016/j.jri.2005.12.001

    authors： Fiore S,Newell ML,Trabattoni D,Thorne C,Gray L,Savasi V,Tibaldi C,Ferrazzi E,Clerici M

    更新日期：2006-06-01 00:00:00

  • Cytokine production in chorioamnionitis.

    abstract：:Lymphohematopoietic cytokines play a significant role in many biological mechanisms including a number of reproductive processes such as ovulation, implantation, placentation, cervical dilation and parturition. Recent experiments have suggested that cytokines play a crucial role in the mechanisms of preterm labor and ...

    journal_title：Journal of reproductive immunology

    pub_type： 杂志文章,评审

    doi：10.1016/s0165-0378(00)00064-4

    authors： Saji F,Samejima Y,Kamiura S,Sawai K,Shimoya K,Kimura T

    更新日期：2000-07-01 00:00:00