Increased sensitivity of the baroreceptor reflex after bacterial endotoxin.

abstract：:Neuroimaging research suggests that cerebral white matter (WM) integrity, as reflected in fractional anisotropy (FA) via diffusion tensor imaging (DTI), is decreased in older adults, especially in the prefrontal regions of the brain. Behavioral investigations of cognitive functioning suggest that some aspects of cogni...

journal_title：Annals of the New York Academy of Sciences

authors： Marks BL,Madden DJ,Bucur B,Provenzale JM,White LE,Cabeza R,Huettel SA

更新日期：2007-02-01 00:00:00

abstract：:Will the development of safe, accurate prenatal diagnosis for Cooley's anemia result in a reduction in the unwanted birth of children with Cooley's anemia in the United States? Since detection of couples at risk only through the birth of an affected child will lead to a minimal reduction in the incidence of the diseas...

journal_title：Annals of the New York Academy of Sciences

authors： Rowley PT,Loader S,Walden ME

更新日期：1985-01-01 00:00:00

abstract：:The proto-oncogene c-myc is involved in multiple cell pathways with opposite effects on cell outcome of death or proliferation. It has been proposed that these different roles depend on the sequestration of c-Myc protein in cellular compartments and/or its phosphorylation. We speculated that subcellular localization o...

journal_title：Annals of the New York Academy of Sciences

authors： Supino R,Favini E,Cuccuru G,Zunino F,Scovassi AI

更新日期：2007-01-01 00:00:00

abstract：:Though only a decade has elapsed since the default network (DN) was first defined as a large-scale brain system, recent years have brought great insight into the network's adaptive functions. A growing theme highlights the DN as playing a key role in internally directed or self-generated thought. Here, we synthesize r...

journal_title：Annals of the New York Academy of Sciences

authors： Andrews-Hanna JR,Smallwood J,Spreng RN

更新日期：2014-05-01 00:00:00

abstract：:Much has been learned during the past decade about the specific retinoid-binding proteins that exist in plasma, and in the intracellular compartment in a number of tissues. Vitamin A is mobilized from liver stores and transported in plasma in the form of the lipid alcohol retinol, bound to a specific transport protein...

journal_title：Annals of the New York Academy of Sciences

authors： Goodman DS

更新日期：1981-02-27 00:00:00

abstract：:Methamphetamine (METH) is a widely used "club drug" that produces neural damage in the brain, including the loss of some neurons. METH-induced striatal neuronal loss has been attenuated by pretreatment with the neurokinin-1 receptor antagonist WIN-51,708 in mice. Using a histologic method, we have observed the interna...

journal_title：Annals of the New York Academy of Sciences

authors： Wang J,Xu W,Ali SF,Angulo JA

更新日期：2008-10-01 00:00:00

abstract：:Globally, increasing acquired antimicrobial resistance among pathogenic bacteria presents an urgent challenge to human and animal health. As a result, significant efforts, such as the One Health Initiative, are underway to curtail and optimize the use of critically important antimicrobials for human medicine in all ap...

journal_title：Annals of the New York Academy of Sciences

authors： Scott HM,Acuff G,Bergeron G,Bourassa MW,Gill J,Graham DW,Kahn LH,Morley PS,Salois MJ,Simjee S,Singer RS,Smith TC,Storrs C,Wittum TE

更新日期：2019-04-01 00:00:00

abstract：:The endometrium acquires the ability to implant the developing embryo within a specific time window, termed the "receptive phase." During this period, the endometrium undergoes pronounced structural and functional changes induced by the ovarian steroids, estrogen and progesterone, which prepare it to be receptive to i...

journal_title：Annals of the New York Academy of Sciences

authors： Bagchi IC,Li Q,Cheon YP

更新日期：2001-09-01 00:00:00

abstract：:In this chapter, we have presented evidence for several potential levels of interaction of NT/N gene products with dopaminergic systems of the brain. We have focused on one manifestation of this interaction related to the effects of antipsychotic drugs on expression of the NT/N gene in two anatomically discrete popula...

journal_title：Annals of the New York Academy of Sciences

authors： Merchant KM,Dobie DJ,Dorsa DM

更新日期：1992-01-01 00:00:00

abstract：:Therapy for mitochondrial diseases is woefully inadequate. How-ever, lack of cure does not equate with lack of treatment. In this review, we consider sequentially several different therapeutic approaches. Palliative therapy is dictated by good medical practice and includes anticonvulsant medication, control of endocri...

journal_title：Annals of the New York Academy of Sciences

authors： Dimauro S,Mancuso M,Naini A

更新日期：2004-04-01 00:00:00

abstract：:Beta-carotene acts as an antioxidant or a pro-oxidant depending on the concentrations that cells are treated with. Oxidative DNA damage is related to apoptosis of various cells. Ataxia-telangiectasia-mutated (ATM), a sensor for DNA-damaging agents, activates a variety of effectors in multiple signaling pathways, such ...

journal_title：Annals of the New York Academy of Sciences

authors： Jang SH,Lim JW,Kim H

更新日期：2009-08-01 00:00:00

abstract：:Tocopherols and tocotrienols (vitamin E) and ascorbic acid (vitamin C) as well as the carotenoids react with free radicals, notably peroxyl radicals, and with singlet molecular oxygen (1O2), this being the basis of their function as antioxidants. RRR-alpha-tocopherol is the major peroxyl radical scavenger in biologica...

journal_title：Annals of the New York Academy of Sciences

authors： Sies H,Stahl W,Sundquist AR

更新日期：1992-09-30 00:00:00

abstract：:Helicobacter pylori is a definite carcinogen whose mechanism of action is still unknown. The aim of this work was (1) to determine the presence of p53 protein and related antibodies in patients affected by various gastric pathologies and chronically infected with H. pylori, and (2) to try to discover a test to be used...

journal_title：Annals of the New York Academy of Sciences

authors： Losi E,Molinari AM,Gazzerro P,Ortega De Luna L,Fera MT,Carbone M,Catania MR,Hasty DL,Rossano F

更新日期：2002-06-01 00:00:00

abstract：:Though several studies show that genetic factors influence individual differences in musical engagement, aptitude, and achievement, no study to date has investigated whether specialization among musically active individuals in terms of choice of instrument and genre is heritable. Using a large twin cohort, we explored...

journal_title：Annals of the New York Academy of Sciences

authors： Mosing MA,Ullén F

更新日期：2018-05-09 00:00:00

abstract：:MRI assessment of myocardial iron and function has revolutionized the treatment of thalassemia major patients. While knowledge of somatic iron stores is vital for iron chelation management, it does not adequately monitor cardiac risk. MRI monitoring of cardiac T2* allows preclinical recognition of myocardial iron, str...

journal_title：Annals of the New York Academy of Sciences

authors： Wood JC,Noetzli L

更新日期：2010-08-01 00:00:00

abstract：:The nearly neutral theory represents a development of Kimura's neutral theory of molecular evolution that makes testable predictions that go beyond a mere null model. Recent evidence has strongly supported several of these predictions, including the prediction that slightly deleterious variants will accumulate in a sp...

journal_title：Annals of the New York Academy of Sciences

authors： Hughes AL

更新日期：2008-01-01 00:00:00

abstract：:The Na,K-ATPase gamma subunit is present primarily in kidney as two splice variants, gammaa and gammab, which differ only at their extracellular N-termini. Two distinct effects of gamma are seen in biochemical Na,K-ATPase assays of mammalian (HeLa) cells transfected with gammaa or gammab, namely, (i) a decrease in K'(...

journal_title：Annals of the New York Academy of Sciences

authors： Blostein R,Pu HX,Scanzano R,Zouzoulas A

更新日期：2003-04-01 00:00:00

abstract：:Acylated aldose dialkyl dithioacetals with bromine undergo replacement of one alkylthio group by bromine. These unstable bromides react, as by fusion with 2,4-bis(trimethylsilyloxy)pyrimidine, to give acylated 1-(pyrimidin-1-yl) derivatives that upon saponification afford acyclic sugar nucleoside analogues, some as se...

journal_title：Annals of the New York Academy of Sciences

authors： Horton D,Baker DC,Kokrady SS

更新日期：1975-08-08 00:00:00

abstract：:The issues of temporal coding and the temporal organization of activity have aroused a great deal of interest in sensory systems, cortex, thalamus, and hippocampus. Strangely, despite the important timing roles attributed to the cerebellum, little consideration has been given to the organization of activity within the...

journal_title：Annals of the New York Academy of Sciences

authors： Isope P,Dieudonné S,Barbour B

更新日期：2002-12-01 00:00:00

abstract：:It is believed that HDL exerts its anti-atherogenic effects through the process of delivering cholesterol from peripheral tissues back to the liver for removal from the body (i.e., reverse cholesterol transport). The metabolic life cycle of HDL lipid and apolipoproteins during reverse cholesterol transport involves bo...

journal_title：Annals of the New York Academy of Sciences

authors： Silver DL,Jiang XC,Arai T,Bruce C,Tall AR

更新日期：2000-05-01 00:00:00

abstract：:The familial myelodysplastic (MDS)/acute leukemia (AL) predisposition syndromes are inherited disorders that lead to significantly increased lifetime risks of MDS and AL development. At present, four recognized syndromes have Clinical Laboratory Improvement Amendments--certified testing for their respective germ-line ...

journal_title：Annals of the New York Academy of Sciences

authors： West AH,Godley LA,Churpek JE

更新日期：2014-03-01 00:00:00

abstract：:Positron emission tomography (PET) is currently the only technology affording three-dimensional measurement of the brain's energy metabolism which is closely coupled to brain function. Studies of glucose metabolism by PET of (18F)-2-fluoro-2-deoxy-D-glucose are therefore widely applied to show the contribution of vari...

journal_title：Annals of the New York Academy of Sciences

authors： Heiss WD,Szelies B,Kessler J,Herholz K

更新日期：1991-01-01 00:00:00

abstract：:Osmotic opening of the blood-brain barrier (BBB) most likely is mediated by modification of interendothelial tight junctions, subsequent to shrinkage of cerebrovascular endothelial cells, and not by stimulation of transendothelial vesicular transport or by channel formation. This paper summarizes evidence for this con...

journal_title：Annals of the New York Academy of Sciences

authors： Rapoport SI,Robinson PJ

更新日期：1986-01-01 00:00:00

abstract：:Three distinct anion exchangers are described that directly or indirectly mediate Cl- transport across the luminal membrane of the proximal tubule cell. Studies on the intact proximal tubule indicate that the Cl(-)-formate exchanger is a major mechanism for Cl- transport under physiologic conditions. As just discussed...

journal_title：Annals of the New York Academy of Sciences

authors： Aronson PS,Kuo SM

更新日期：1989-01-01 00:00:00

abstract：:Structural analysis of secretin in solution has demonstrated extended helical domains within both amino- and carboxyl-terminal halves, with a possible turn in between. However, the conformation of this peptide as it resides in its binding site within the receptor has not been established. In the work reported here, we...

journal_title：Annals of the New York Academy of Sciences

authors： Dong M,Wang Y,Miller LJ

更新日期：2000-01-01 00:00:00

abstract：:Jopock (Jpk), a transacting factor associated with the position-specific regulatory element of murine Hoxa-7, has shown to induce cell death in both prokaryotic and eukaryotic cells when introduced and overexpressed. Since Jpk protein harbors a transmembrane domain (TM) and a putative endoplasmic reticulum (ER) -reten...

journal_title：Annals of the New York Academy of Sciences

authors： Kim HS,Kong KA,Chung H,Park S,Kim MH

更新日期：2007-01-01 00:00:00

abstract：:Over the last years, El Sistema--the Venezuelan project started in 1975 and now acknowledged worldwide as the most significant example of collective music education--has inspired a profusion of remarkable initiatives on all continents. From the original impulse by founder José Antonio Abreu, strong social principles o...

journal_title：Annals of the New York Academy of Sciences

authors： Majno M

更新日期：2012-04-01 00:00:00

abstract：:Eighty-seven reports of patients with seizures induced by listening and/or playing music and one personal observation are reviewed. Music-induced (or musicogenic) seizures are currently classified among the reflex seizures precipitated by complex stimuli. According to the available information, they are defined as foc...

journal_title：Annals of the New York Academy of Sciences

authors： Avanzini G

更新日期：2003-11-01 00:00:00

abstract：:Mustard gas (sulfur mustard, SM), a highly vesicating chemical warfare agent, was first deployed in warfare in 1917 and recently during the Iraq-Iran war (1980s) and Syrian conflicts (2000s); however, the threat of exposure from stockpiles and old artillery shells still looms large. Whereas research has been long ongo...

journal_title：Annals of the New York Academy of Sciences

authors： Mishra N,Raina K,Agarwal R

更新日期：2020-12-10 00:00:00

abstract：:The relationship between chaos and quantum mechanics has been somewhat uneasy--even stormy, in the minds of some people. However, much of the confusion may stem from inappropriate comparisons using formal analyses. In contrast, our starting point here is that a complete dynamical description requires a full understand...

journal_title：Annals of the New York Academy of Sciences

authors： Habib S,Bhattacharya T,Greenbaum B,Jacobs K,Shizume K,Sundaram B

更新日期：2005-06-01 00:00:00