Heterogeneity of anion exchangers mediating chloride transport in the proximal tubule.

abstract：:Bacteria can exhibit high levels of resistance to one or more environmental stresses such as temperature, osmolarity, radiation, pH, starvation, as well as resistance to noxious chemicals and antibiotics. Yet evolution has not optimized stress resistance in all bacteria to all stresses. Even within a species like Esch...

journal_title：Annals of the New York Academy of Sciences

authors： Ferenci T,Spira B

更新日期：2007-10-01 00:00:00

abstract：:The autonomic nervous system consists of sympathetic, parasympathetic, and enteric ganglia and also of a specialized neuroendocrine derivative, the adrenomedullary chromaffin cells. ...

journal_title：Annals of the New York Academy of Sciences

authors： Kalcheim C,Langley K,Unsicker K

更新日期：2002-10-01 00:00:00

abstract：:Gene regulation mechanisms have evolved allowing cells to finetune the level of "endogenous" oxidative stress and to cope with increased free radicals from external sources. Levels of H2O2 are tightly controlled in E. coli by OxyR, which is activated by H2O2 to increase scavenging activities and limit H2O2 generation ...

journal_title：Annals of the New York Academy of Sciences

authors： González-Flecha B,Demple B

更新日期：2000-01-01 00:00:00

abstract：:We found that gamma-tocopherol, the predominant vitamin E form in diets, but not alpha-tocopherol, which is the exclusive form of vitamin E in most supplements, exhibited antiproliferation effect on prostate (PC-3, LNCaP) and lung (A549) cancer cells. gamma-Tocopherol induced apoptosis in androgen-sensitive LNCaP but ...

journal_title：Annals of the New York Academy of Sciences

authors： Jiang Q,Wong J,Ames BN

更新日期：2004-12-01 00:00:00

abstract：:Francisella tularensis is one of the most pathogenic pathogens known, especially when disseminated as a small particle aerosol. Because of this, it was developed into a biological warfare agent by several states during the 20th century. Nowadays, concerns remain about the potential of this pathogen to cause widespread...

journal_title：Annals of the New York Academy of Sciences

authors： Wayne Conlan J,Oyston PC

更新日期：2007-06-01 00:00:00

abstract：:Human alpha 2-antiplasmin (alpha 2AP) is the primary inhibitor of plasmin-mediated fibrinolysis and is an efficient substrate of activated factor XIII (FXIIIa). Among 452 amino acid residues in alpha 2AP, Gln2 is believed to be the sole FXIIIa-reactive site that participates in crosslinking alpha 2AP to fibrin. We stu...

journal_title：Annals of the New York Academy of Sciences

authors： Lee KN,Lee CS,Tae WC,Jackson KW,Christiansen VJ,McKee PA

更新日期：2001-01-01 00:00:00

abstract：:Relaxin has been validated as a cardiotropic hormone, being produced by the heart and acting on specific heart receptors. Evidence is accumulating that it could hamper the pathophysiologic mechanisms of ischemic heart disease. Time is ripe to study relaxin as a cardiotropic drug, as recombinant human relaxin (hrRLX) i...

journal_title：Annals of the New York Academy of Sciences

authors： Bani D,Nistri S,Sacchi TB,Bigazzi M

更新日期：2005-05-01 00:00:00

abstract：:The hyperactivation of glutamate receptors, especially those of the N-methyl-d-aspartate subtype (NMDA), can induce excess calcium entry into cells, leading to neuronal death. Since the anesthetic gas xenon behaves as an NMDA antagonist, the present article investigated, by distinct morphological approaches and after ...

journal_title：Annals of the New York Academy of Sciences

authors： Natale G,Cattano D,Abramo A,Forfori F,Fulceri F,Fornai F,Paparelli A,Giunta F

更新日期：2006-08-01 00:00:00

abstract：:Without landmarks, navigation is based on information about self-velocity, which is transformed to position or orientation by a process called path integration. Simple path integration tasks, such as reaching a previously seen goal by blindfolded locomotion, were often considered to be automatic and not influenced by ...

journal_title：Annals of the New York Academy of Sciences

authors： Glasauer S,Stein A,Günther AL,Flanagin VL,Jahn K,Brandt T

更新日期：2009-05-01 00:00:00

abstract：:These studies demonstrate that photochemotherapy can be successfully evaluated in animal models. The therapy mediates specific suppression of immune responses and appears to operate at the level of the effector T cells. Future studies will focus on isolation and characterization of the host response to photochemothera...

journal_title：Annals of the New York Academy of Sciences

authors： Berger CL,Edelson RL,Edwards N,Sanchez J,Coppey L,He X,Marboe C,Rose E

更新日期：1991-12-30 00:00:00

abstract：:This article focuses on the importance of social engagement and the behavioral and neurophysiological mechanisms that allow individuals to reduce psychological and physical distance. A model of social engagement derived from the Polyvagal Theory is presented. The model emphasizes phylogeny as an organizing principle a...

journal_title：Annals of the New York Academy of Sciences

authors： Porges SW

更新日期：2003-12-01 00:00:00

abstract：:Neuroendocrine tumors are very heterogeneous, develop from a variety of tissues, and can be difficult to diagnose. Without the clinical manifestation of metastases, it is often difficult to characterize them as malignant. Even so-called completely (R0) resected tumors can spread clinically visible metastases within a ...

journal_title：Annals of the New York Academy of Sciences

authors： Koch CA,Gimm O,Vortmeyer AO,Al-Ali HK,Lamesch P,Ott R,Kluge R,Bierbach U,Tannapfel A

更新日期：2006-08-01 00:00:00

abstract：:Imatinib is a selective tyrosine kinase inhibitor used for the treatment of Philadelphia chromosome-positive leukemias and other malignancies. An important clinical observation is that imatinib can affect the function of normal nonmalignant cells resulting in myelosuppression in treated patients. This observation is s...

journal_title：Annals of the New York Academy of Sciences

authors： Balabanov S,Appel S,Kanz L,Brossart P,Brümmendorf TH

更新日期：2005-06-01 00:00:00

abstract：:Bioelectrical impedance spectroscopy (BIS) can provide estimates of body composition for both whole body (WB) and body segments (BS). In normal, healthy subjects, BS measurements may be expected to serve as surrogates for WB indices; however, very little is known about this correspondence in people suffering from acut...

journal_title：Annals of the New York Academy of Sciences

authors： Mazariegos M,Klassen P,Solomons NW,Fürst P

更新日期：2000-05-01 00:00:00

abstract：:Tularemia is a disease caused by several subspecies of Francisella tularensis, although the severity of the disease varies greatly from subspecies to subspecies. Currently, there are four recognized subspecies (tularensis, holarctica, mediasiatica, and novicida), in addition to a second Francisella species, F. philomi...

journal_title：Annals of the New York Academy of Sciences

authors： Keim P,Johansson A,Wagner DM

更新日期：2007-06-01 00:00:00

abstract：:Eighty-seven reports of patients with seizures induced by listening and/or playing music and one personal observation are reviewed. Music-induced (or musicogenic) seizures are currently classified among the reflex seizures precipitated by complex stimuli. According to the available information, they are defined as foc...

journal_title：Annals of the New York Academy of Sciences

authors： Avanzini G

更新日期：2003-11-01 00:00:00

abstract：:Red spruce (Picea rubens Sarg.) and balsam fir (Abies balsamea (L.) Mill.) were present by 13,700 years B.C.E. in the Catskills Mountains of southeastern New York State. These conifers were, and still are, largely confined to the eastern and far western portions of the region. A gap in the distribution exists between ...

journal_title：Annals of the New York Academy of Sciences

authors： Kudish M

更新日期：2013-09-01 00:00:00

abstract：:Nicergoline (NE)--a cerebral vasodilator with nicotinic acid esterified in its molecule--and Antagonic-Stress (AS) composition--a neurometabolic nootropic, also containing nicotinic acid but with fast and prolonged release--were evaluated in senile dementia of Alzheimer's type (SDAT), mild to moderate intensity (DSM-I...

journal_title：Annals of the New York Academy of Sciences

authors： Schneider F,Popa R,Mihalas G,Stefanigă P,Mihalas IG,Măties R,Mateescu R

更新日期：1994-06-30 00:00:00

abstract：:Bone marrow cells of various animal species and the human produce a group of bioregulatory peptides called myelopeptides (MPs). A highly purified myelopeptide (MP) fraction and some individual molecules have been isolated from the supernatant of the porcine bone marrow cell culture by successive gel chromatography and...

journal_title：Annals of the New York Academy of Sciences

authors： Petrov RV

更新日期：1993-06-23 00:00:00

abstract：:Plasmacytoid dendritic cells (pDCs) are a rare population of circulating cells that selectively express Toll-like receptors (TLR)7 and TLR9 and have the capacity to produce large amounts of type I interferons (IFNs) in response to viruses or host-derived nucleic acid-containing complexes. Through the production of typ...

journal_title：Annals of the New York Academy of Sciences

authors： Lande R,Gilliet M

更新日期：2010-01-01 00:00:00

abstract：:Corn flour and maize meal fortification can benefit the consumer when the added nutrient contents are in amounts appropriate to address nutrient gaps. Legislative instruments (standards and regulations) are needed to provide guidance to the producers and food control authorities. We reviewed a number of national stand...

journal_title：Annals of the New York Academy of Sciences

authors： Makhumula P,Dary O,Guamuch M,Tom C,Afidra R,Rambeloson Z

更新日期：2014-04-01 00:00:00

abstract：:The pregnant uterus is unique because of the dramatic functional changes that occur in the peripartum period. To promote the concept that we have a relatively poor understanding of the physiology of parturition, we will posit 10 facts that are so obvious and so clearly accepted as facts that they probably are not even...

journal_title：Annals of the New York Academy of Sciences

authors： Young RC

更新日期：2007-04-01 00:00:00

abstract：:We and others recently showed that fever induced by intravenously or intraperitoneally injected lipopolysaccharide (LPS) may involve brain signaling via hepatic vagal afferents. This suggests that LPS fever may be initiated by mediators released mainly by cells in the liver, presumably macrophages (Kupffer cells, Kc)....

journal_title：Annals of the New York Academy of Sciences

authors： Blatteis CM,Sehic E,Li S

更新日期：1998-09-29 00:00:00

abstract：:Pelizaeus-Merzbacher disease (PMD) is a dysmyelinating disorder of the central nervous system typically caused by duplications or missense mutations of the proteolipid protein (PLP) gene. Most investigators have found that peripheral nerve function and structure is normal in PMD patients. We have found that null mutat...

journal_title：Annals of the New York Academy of Sciences

authors： Garbern JY,Cambi F,Lewis R,Shy M,Sima A,Kraft G,Vallat JM,Bosch EP,Hodes ME,Dlouhy S,Raskind W,Bird T,Macklin W,Kamholz J

更新日期：1999-09-14 00:00:00

abstract：:Neurologic symptoms were the earliest and most prominent symptoms recorded in Michigan farm residents exposed to PBB as compared to a non-PBB exposed control farm population in Wisconsin. In Michigan (particularly among males) those who exhibited the most marked symptoms tended to show diminished performance as assess...

journal_title：Annals of the New York Academy of Sciences

authors： Valciukas JA,Lilis R,Anderson HA,Wolff MS,Petrocci M

更新日期：1979-05-31 00:00:00

abstract：:We review the effects of two transcription factor decoy oligonucleotides on apoptosis of human osteoclasts (OCs). The first decoy molecule was designed to inhibit nuclear factor kappa-B (NF-kappaB) binding to target sequence, the second to increase estrogen receptor (ER) alpha expression. We found that both decoy mole...

journal_title：Annals of the New York Academy of Sciences

authors： Piva R,Penolazzi L,Zennaro M,Bianchini E,Magri E,Borgatti M,Lampronti I,Lambertini E,Tavanti E,Gambari R

更新日期：2006-12-01 00:00:00

abstract：:The loss of E-cadherin expression or function in epithelial carcinomas has long been thought as a primary reason for disruption of tight epithelial cell-cell contacts and release of invasive tumor cells from the primary tumor. Indeed, E-cadherin serves as a widely acting suppressor of invasion and growth of epithelial...

journal_title：Annals of the New York Academy of Sciences

authors： Hazan RB,Qiao R,Keren R,Badano I,Suyama K

更新日期：2004-04-01 00:00:00

abstract：:Auditory brainstem potentials were recorded from various scalp and nasopharyngeal sites referenced both to a noncephalic site and to certain scalp locations in normal humans. The distribution of amplitudes and latencies of the components were defined. There were significant amplitude, polarity, and latency asymmetries...

journal_title：Annals of the New York Academy of Sciences

authors： Starr A,Squires K

更新日期：1982-01-01 00:00:00

abstract：:Neovascularization is a hallmark of cancer progression. Suppression of the angiogenic response in tumors has been associated with inhibition and even regression of total tumor mass. Therefore, the derivation of synthetic or natural products that could interfere with proangiogenic signaling pathways can greatly impact ...

journal_title：Annals of the New York Academy of Sciences

authors： Iruela-Arispe ML,Carpizo D,Luque A

更新日期：2003-05-01 00:00:00

abstract：:Rocky Mountain spotted fever (RMSF) caused by Rickettsia rickettsii is a severe rickettsiosis that occurs in nearly every state of the continental USA. RMSF is endemic in Central and Southern America, with recent well-documented cases in Mexico, Costa Rica, Panama, Colombia, Brazil, and Argentina. RMSF is the most mal...

journal_title：Annals of the New York Academy of Sciences

authors： Eremeeva ME,Dasch GA

更新日期：2009-05-01 00:00:00