Role of aerobic fitness and aging on cerebral white matter integrity.

Abstract:

:Neuroimaging research suggests that cerebral white matter (WM) integrity, as reflected in fractional anisotropy (FA) via diffusion tensor imaging (DTI), is decreased in older adults, especially in the prefrontal regions of the brain. Behavioral investigations of cognitive functioning suggest that some aspects of cognition may be better preserved in older adults who possess higher levels of aerobic fitness. There are only a few studies, however, investigating potential mechanisms for the improvements in aerobic fitness. Our study suggests that greater aerobic fitness may be related to greater WM integrity in select brain regions.

journal_name

Ann N Y Acad Sci

authors

Marks BL,Madden DJ,Bucur B,Provenzale JM,White LE,Cabeza R,Huettel SA

doi

10.1196/annals.1379.022

subject

Has Abstract

pub_date

2007-02-01 00:00:00

pages

171-4

eissn

0077-8923

issn

1749-6632

pii

1097/1/171

journal_volume

1097

pub_type

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