Adolescent stress alters ethanol ingestion and agonistic behavior in the male golden hamster.

abstract：:Calcitonin gene-related peptide has been identified by immunocytochemistry within the thymus of fetal through aged adult mice. Calcitonin gene-related peptide positive nerves are observed from embryonic day 17 throughout the lifespan of the mouse. A sparse cell population positive for CGRP is first observed during the...

journal_title：Annals of the New York Academy of Sciences

authors： Bulloch K,McEwen BS,Diwa A,Radojcic T,Hausman J,Baird S

更新日期：1994-11-25 00:00:00

abstract：:Neovascularization is a hallmark of cancer progression. Suppression of the angiogenic response in tumors has been associated with inhibition and even regression of total tumor mass. Therefore, the derivation of synthetic or natural products that could interfere with proangiogenic signaling pathways can greatly impact ...

journal_title：Annals of the New York Academy of Sciences

authors： Iruela-Arispe ML,Carpizo D,Luque A

更新日期：2003-05-01 00:00:00

abstract：:Agonist interactions with release processes do not validate autoreceptor operation. Instead, the data suggests that autoreceptors function as homoreceptors. Declining efficacy of agonist inhibition of transmitter release with increasing stimulation "intensity" is not assignable to competition with endogenous transmitt...

journal_title：Annals of the New York Academy of Sciences

authors： Kalsner S

更新日期：1990-01-01 00:00:00

abstract：:The muscular dystrophies, which cause progressive weakening of the skeletal muscles, are frequently associated with cardiomyopathy. In fact, the leading cause of mortality in patients with Duchenne muscular dystrophy, the most common and most severe type of muscular dystrophy, is heart failure due to cardiomyopathy. T...

journal_title：Annals of the New York Academy of Sciences

authors： Kuno A,Tanno M,Horio Y

更新日期：2015-08-01 00:00:00

abstract：:I2-imidazoline receptors (I2-IR) are characterized by their high affinity for imidazolines and guanidines and medium affinity for imidazolidines. The differential recognition of I2-IR by amiloride led to subtype these sites as amiloride-sensitive (I2A-IR) and amiloride-insensitive (I2B-IR). I2-IR labeled with [3H]idaz...

journal_title：Annals of the New York Academy of Sciences

authors： Olmos G,Alemany R,Boronat MA,García-Sevilla JA

更新日期：1999-06-21 00:00:00

abstract：:A rabbit antimouse brain theta reagent was made specific for cells of the T lineage by absorption in vivo in nude mice. When used in double fluorescence together with an antimouse immunoglobulin reagent, four types of cells were found in spleen and lymph nodes of both normal and nude mice: Ig+thetaBr-, Ig-thetaBr+, Ig...

journal_title：Annals of the New York Academy of Sciences

authors： Loor F,Roelants GE

更新日期：1975-06-30 00:00:00

abstract：:DNA microarray analysis was conducted to investigate the transcriptional responses of the human monocytic leukemia cell line THP-1 to infection by Chlamydia trachomatis or Coxiella burnetii. RNA was isolated from mock infected cells and cells infected for 36 hours using TRIzol reagent. Biotinylated probes synthesized ...

journal_title：Annals of the New York Academy of Sciences

authors： Ren Q,Robertson SJ,Howe D,Barrows LF,Heinzen RA

更新日期：2003-06-01 00:00:00

abstract：:As a result of intensive investigation, particularly in the pharmaceutical industry, a number of potent and selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonists have been discovered. The structure activity relationship studies that led to the discovery of these mGluR5 antagonists are presented in t...

journal_title：Annals of the New York Academy of Sciences

authors： Carroll FI

更新日期：2008-10-01 00:00:00

abstract：:It is well established for both rat and man that the total testosterone concentration within the testis is far higher than that in serum. We know for the rat that intratesticular testosterone can be reduced by 50-60% without an adverse effect on spermatogenesis but that the required intratesticular testosterone concen...

journal_title：Annals of the New York Academy of Sciences

authors： Jarow JP,Zirkin BR

更新日期：2005-12-01 00:00:00

abstract：:At the alpha(2A)-autoreceptors on the sympathetic nerve terminals of the human atrial appendages and rabbit pulmonary artery, rilmenidine and oxymetazoline exhibit different properties (antagonism and agonism, respectively). These opposite pharmacodynamic properties of alpha(2)-adrenoceptor ligands seem to be due to s...

journal_title：Annals of the New York Academy of Sciences

authors： Molderings GJ,Bonisch H,Bruss M,Gothert M

更新日期：2003-12-01 00:00:00

abstract：:The fate of a neuron in the developing brain to multiply, differentiate, or die in an apoptotic manner depends on the expression of genes that are involved in regulating the cell cycle. Recent studies determined the involvement of several genes, including cyclin A and B2, in dopamine-induced apoptosis in cultured chic...

journal_title：Annals of the New York Academy of Sciences

authors： Porat S,Simantov R

更新日期：1999-01-01 00:00:00

abstract：:Physicians have used various forms of antipyretic therapy since antiquity to lower the temperature of febrile patients. Nevertheless, it has yet to be determined whether the benefits of antipyretic therapy outweigh its risks. It is not known, for example, if core temperatures encountered during the febrile state ever ...

journal_title：Annals of the New York Academy of Sciences

authors： Mackowiak PA,Plaisance KI

更新日期：1998-09-29 00:00:00

abstract：:Explicit memory refers to the conscious retrieval of past information or experiences, whereas implicit memory refers to an unintentional or nonconscious form of retrieval. Much of the literature in cognitive psychology and cognitive neuroscience has focused on differences between explicit and implicit memory, and the ...

journal_title：Annals of the New York Academy of Sciences

authors： Dew ITZ,Cabeza R

更新日期：2011-04-01 00:00:00

abstract：:Nuclear factor-kappa B (NF-kappaB) is a transcription factor that resides in the cytoplasm of every cell and translocates to the nucleus when activated. Its activation is induced by a wide variety of agents including stress, cigarette smoke, viruses, bacteria, inflammatory stimuli, cytokines, free radicals, carcinogen...

journal_title：Annals of the New York Academy of Sciences

authors： Ahn KS,Aggarwal BB

更新日期：2005-11-01 00:00:00

abstract：:Recent studies suggest that the symptoms associated with endometriosis are the result of local peritoneal inflammation. Increased concentrations of activated pelvic macrophages and lymphocytes and the elevated levels of specific cytokines and growth factors reviewed above support this hypothesis. The precise roles of ...

journal_title：Annals of the New York Academy of Sciences

authors： Taylor RN,Ryan IP,Moore ES,Hornung D,Shifren JL,Tseng JF

更新日期：1997-09-26 00:00:00

abstract：:The mechanism by which neurons and neurosecretory cells govern the expression and the exocytic discharge of their clear and dense-core vesicles had remained unclear until recently when studies in the neurosecretory cell model PC12 revealed these processes to be orchestrated by the transcriptional repressor neuron rest...

journal_title：Annals of the New York Academy of Sciences

authors： D'Alessandro R,Klajn A,Meldolesi J

更新日期：2009-01-01 00:00:00

abstract：:This paper discusses the repatriation of human remains to indigenous peoples in Australia and the United States and the role anthropologists play in the construction of past, present, and future identities for contemporary indigenous peoples. Using examples from both countries, I suggest that many of the participants ...

journal_title：Annals of the New York Academy of Sciences

authors： Cantwell AM

更新日期：2000-01-01 00:00:00

abstract：:Phagocytes play a major role in several diseases. In particular mononuclear phagocyte-derived foam cells have a prominent role in the development of the atherosclerotic lesions. Macrophages are present in all stages of atherogenesis; they internalize lipoproteins and accumulate cholesterol. Moreover, lipid-filled macr...

journal_title：Annals of the New York Academy of Sciences

authors： Paoletti R,Bellosta S,Bernini F

更新日期：1997-12-15 00:00:00

abstract：:Entomopathogenic fungi are promising alternatives to chemical acaricides in controlling tick populations; however, biological formulations are required to improve conidial performance of these pathogens in the field. This study evaluated the effect of in vitro treatment of Rhipicephalus sanguineus with conidial formul...

journal_title：Annals of the New York Academy of Sciences

authors： Reis RC,Fernandes EK,Bittencourt VR

更新日期：2008-12-01 00:00:00

abstract：:The objective of this article is to investigate the influence of endothelin-1 (ET-1) on human monocyte Na(+)/H(+) exchanger (NHE) activity and on the atherosclerosis-related monocyte functions. ET-1 caused an increase in pHi and in (22)Na influx of monocytes. A reversal of ET-1 effect on pHi was observed in the presen...

journal_title：Annals of the New York Academy of Sciences

authors： Koliakos G,Befani C,Paletas K,Kaloyianni M

更新日期：2007-01-01 00:00:00

abstract：:Lesion, stimulation, and pharmacological studies point to separate hypothalamic control of pulsatile FSH and LH secretion. LH release is controlled by a region extending from the preoptic area to the anterior and mid-median eminence, whereas FSH release is controlled by a region extending from the dorsal anterior hypo...

journal_title：Annals of the New York Academy of Sciences

authors： McCann SM,Marubayashi U,Sun HQ,Yu WH

更新日期：1993-05-28 00:00:00

abstract：:Endometriosis is a complex gynecologic disorder that has long been recognized as showing heritable tendencies, with recurrence risks of 5-7% for first-degree relatives. Familial and epidemiologic studies support that this disease is a genetic disorder of polygenic/multifactorial inheritance. The current investigationa...

journal_title：Annals of the New York Academy of Sciences

authors： Bischoff F,Simpson JL

更新日期：2004-12-01 00:00:00

abstract：:Different estrogen-3-sulfates (estrone-3-sulfate, estradiol-3-sulfate, and estriol-3-sulfate) can provoke important biologic responses in different mammary cancer cell lines; there is a significant increase in progesterone receptor. However, no significant effect was observed with estrogen-17-sulfates. The reason for ...

journal_title：Annals of the New York Academy of Sciences

authors： Pasqualini JR,Gelly C,Nguyen BL

更新日期：1990-01-01 00:00:00

abstract：:Why does music pervade our lives and those of all known human beings living today and in the recent past? Why do we feel compelled to engage in musical activity, or at least simply enjoy listening to music even if we choose not to actively participate? I argue that this is because musicality--communication using varia...

journal_title：Annals of the New York Academy of Sciences

authors： Mithen S

更新日期：2009-07-01 00:00:00

abstract：:Research in the area of adolescent alcohol use is progressing rapidly, as exemplified by the chapters in this section. Basic animal research in rodents has revealed adolescents to be more sensitive than adults to ethanol-induced disruptions in brain plasticity, although adolescents conversely are relatively insensitiv...

journal_title：Annals of the New York Academy of Sciences

authors： Spear LP

更新日期：2004-06-01 00:00:00

abstract：:Translational medicine describes a bench-to-bedside approach that eventually converts findings from basic scientific studies into real-world clinical research. It encompasses new treatments, advanced equipment, medical procedures, preventive and diagnostic approaches creating a bridge between basic studies and clinica...

journal_title：Annals of the New York Academy of Sciences

authors： Amirmahani F,Ebrahimi N,Molaei F,Faghihkhorasani F,Jamshidi Goharrizi K,Mirtaghi SM,Borjian-Boroujeni M,Hamblin MR

更新日期：2021-01-06 00:00:00

abstract：:Between 4 and 13% of people with schizophrenia commit suicide and between 25 and 50% make a suicide attempt, a reflection of the devastating toll this syndrome takes on the quality of life, that is, the subjective and objective sense of well-being. Many risk factors for suicide in schizophrenia have been identified, t...

journal_title：Annals of the New York Academy of Sciences

authors： Meltzer HY

更新日期：2001-04-01 00:00:00

abstract：:Septic shock is a systemic response to severe bacterial infections, generally caused by Gram-negative bacterial endotoxins, with multiple manifestations such as hypotension, tissue injury, disseminated intravascular coagulation, and multi-organ failure. All these effects, are induced by the generation of pro-inflammat...

journal_title：Annals of the New York Academy of Sciences

authors： Martínez C,Arranz A,Juarranz Y,Abad C,García-Gómez M,Rosignoli F,Leceta J,Gomariz RP

更新日期：2006-07-01 00:00:00

abstract：:The risk of cardiovascular (CV) disease increases in patients with rheumatoid arthritis (RA). This is due to a number of different triggers including traditional and disease-related factors. Among established risk factors for CV disease, smoking may exert a more dangerous effect on arterial wall in RA than in the gene...

journal_title：Annals of the New York Academy of Sciences

authors： Gerli R,Sherer Y,Bocci EB,Vaudo G,Moscatelli S,Shoenfeld Y

更新日期：2007-06-01 00:00:00

abstract：:Gene regulation mechanisms have evolved allowing cells to finetune the level of "endogenous" oxidative stress and to cope with increased free radicals from external sources. Levels of H2O2 are tightly controlled in E. coli by OxyR, which is activated by H2O2 to increase scavenging activities and limit H2O2 generation ...

journal_title：Annals of the New York Academy of Sciences

authors： González-Flecha B,Demple B

更新日期：2000-01-01 00:00:00